Multigene pathway-based analyses identify nasopharyngeal carcinoma risk associations for cumulative adverse effects of TERT-CLPTM1L and DNA double-strand breaks repair

International Journal of Cancer

Volumn 135, Issue 7, 2014, Pages 1634-1645

  Yee Ko, Josephine Mun ^a   Dai, Wei ^a   Wun Wong, Elibe Hiu ^a   Kwong, Dora ^a   Ng, Wai Tong ^a,b   Lee, Anne ^a,c   Kai Cheong Ngan, Roger ^a,d   Chung Yau, Chun ^a,e   Tung, Stewart ^a,f   Li Lung, Maria ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b PAMELA YOUDE NETHERSOLE EASTERN HOSPITAL   (Hong Kong)

^c THE UNIVERSITY OF HONG KONG SHENZHEN HOSPITAL   (China)

^d QUEEN ELIZABETH HOSPITAL   (Hong Kong)

^e PRINCESS MARGARET HOSPITAL   (Hong Kong)

^f TUEN MUN HOSPITAL   (Hong Kong)

Author keywords

BLM; CCDC170; DNA DSB repair; familial NPC; genetic susceptibility; NHEJ; NPC; pathway associations; TERT

Indexed keywords

ATM PROTEIN; ATR PROTEIN; BLOOM SYNDROME HELICASE; BRCA1 PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; DNA POLYMERASE; FANCONI ANEMIA GROUP E PROTEIN; FANCONI ANEMIA GROUP G PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN KINASE C; PROTEIN MSH6; PROTEIN P53; RAD51 PROTEIN; TELOMERASE REVERSE TRANSCRIPTASE; XRCC4 PROTEIN;

ARTICLE; CANCER REGISTRY; CANCER RISK; CHINESE; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMOLOGOUS RECOMBINATION; HONG KONG; HUMAN; MAJOR CLINICAL STUDY; MALE; MISMATCH REPAIR; MULTIGENE FAMILY; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TERT CLPTM1L GENE; TUMOR GENE;

BLM; CCDC170; DNA DSB REPAIR; FAMILIAL NPC; GENETIC SUSCEPTIBILITY; NHEJ; NPC; PATHWAY ASSOCIATIONS; TERT;

CASE-CONTROL STUDIES; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION PROFILING; GENOTYPE; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MULTIGENE FAMILY; NASOPHARYNGEAL NEOPLASMS; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RISK FACTORS; SIGNAL TRANSDUCTION; TELOMERASE; TUMOR MARKERS, BIOLOGICAL;

EID: 84904468367     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28802     Document Type: Article

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