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Volumn 39, Issue 9, 2014, Pages 2170-2178

Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia

Author keywords

[No Author keywords available]

Indexed keywords

ARIPIPRAZOLE; NEUREXIN; NEUREXIN 1; OLANZAPINE; PLACEBO; QUETIAPINE; RISPERIDONE; UNCLASSIFIED DRUG; ZIPRASIDONE; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; NEUROLEPTIC AGENT; NRXN1 PROTEIN, HUMAN;

EID: 84904463987     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2014.65     Document Type: Article
Times cited : (22)

References (52)
  • 1
    • 84863906791 scopus 로고    scopus 로고
    • Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia
    • Apud JA, Zhang F, Decot H, Bigos KL, Weinberger DR (2012). Genetic variation in KCNH2 associated with expression in the brain of a unique hERG isoform modulates treatment response in patients with schizophrenia. Am J Psychiatry 169: 725-734.
    • (2012) Am J Psychiatry , vol.169 , pp. 725-734
    • Apud, J.A.1    Zhang, F.2    Decot, H.3    Bigos, K.L.4    Weinberger, D.R.5
  • 2
  • 3
  • 7
    • 84876374695 scopus 로고    scopus 로고
    • Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs
    • Chen X, Shen Y, Zhang F, Chiang C, Pillalamarri V, Blumenthal I et al (2013). Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs. Am J Hum Genet 92: 375-386.
    • (2013) Am J Hum Genet , vol.92 , pp. 375-386
    • Chen, X.1    Shen, Y.2    Zhang, F.3    Chiang, C.4    Pillalamarri, V.5    Blumenthal, I.6
  • 12
    • 0037630627 scopus 로고    scopus 로고
    • Introns in gene evolution
    • Fedorova L, Fedorov A (2003). Introns in gene evolution. Genetica 118: 123-131.
    • (2003) Genetica , vol.118 , pp. 123-131
    • Fedorova, L.1    Fedorov, A.2
  • 15
    • 35748929069 scopus 로고    scopus 로고
    • Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms
    • Hishimoto A, Liu QR, Drgon T, Pletnikova O, Walther D, Zhu XG et al (2007). Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms. Hum Mol Genet 16: 2880-2891.
    • (2007) Hum Mol Genet , vol.16 , pp. 2880-2891
    • Hishimoto, A.1    Liu, Q.R.2    Drgon, T.3    Pletnikova, O.4    Walther, D.5    Zhu, X.G.6
  • 16
    • 55649099694 scopus 로고    scopus 로고
    • Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia
    • Ikeda M, Yamanouchi Y, Kinoshita Y, Kitajima T, Yoshimura R, Hashimoto S et al (2008). Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia. Pharmacogenomics 9: 1437-1443.
    • (2008) Pharmacogenomics , vol.9 , pp. 1437-1443
    • Ikeda, M.1    Yamanouchi, Y.2    Kinoshita, Y.3    Kitajima, T.4    Yoshimura, R.5    Hashimoto, S.6
  • 18
    • 51649107017 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications increase risk of schizophrenia
    • International Schizophrenia Consortium
    • International Schizophrenia Consortium (2008). Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature 455: 237-241.
    • (2008) Nature , vol.455 , pp. 237-241
  • 19
    • 0345690100 scopus 로고    scopus 로고
    • Half a century of antipsychotics and still a central role for dopamine D2 receptors
    • Kapur S, Mamo D (2003). Half a century of antipsychotics and still a central role for dopamine D2 receptors. Prog Neuropsychopharmacol Biol Psychiatry 27: 1081-1090.
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 1081-1090
    • Kapur, S.1    Mamo, D.2
  • 21
    • 38349106160 scopus 로고    scopus 로고
    • Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia
    • Kirov G, Gumus D, Chen W, Norton N, Georgieva L, Sari M et al (2008). Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet 17: 458-465.
    • (2008) Hum Mol Genet , vol.17 , pp. 458-465
    • Kirov, G.1    Gumus, D.2    Chen, W.3    Norton, N.4    Georgieva, L.5    Sari, M.6
  • 23
    • 84864340439 scopus 로고    scopus 로고
    • Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110delta inhibition as a potential therapeutic strategy
    • Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F et al (2012). Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110delta inhibition as a potential therapeutic strategy. Proc Natl Acad Sci USA 109: 12165-12170.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 12165-12170
    • Law, A.J.1    Wang, Y.2    Sei, Y.3    O'donnell, P.4    Piantadosi, P.5    Papaleo, F.6
  • 26
    • 84863904206 scopus 로고    scopus 로고
    • The emerging potential of pharmacogenetics in psychiatry
    • Lotrich FE (2012). The emerging potential of pharmacogenetics in psychiatry. Am J Psychiatry 169: 681-683.
    • (2012) Am J Psychiatry , vol.169 , pp. 681-683
    • Lotrich, F.E.1
  • 27
    • 84864342355 scopus 로고    scopus 로고
    • Pharmacogenetics in psychiatry: Translating research into clinical practice
    • Malhotra AK, Zhang JP, Lencz T (2012a). Pharmacogenetics in psychiatry: translating research into clinical practice. Mol Psychiatry 17: 760-769.
    • (2012) Mol Psychiatry , vol.17 , pp. 760-769
    • Malhotra, A.K.1    Zhang, J.P.2    Lencz, T.3
  • 28
    • 84865975078 scopus 로고    scopus 로고
    • Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain
    • Malhotra AK, Correll CU, Chowdhury NI, Müller DJ, Gregersen PK, Lee AT et al (2012b). Association between common variants near the melanocortin 4 receptor gene and severe antipsychotic drug-induced weight gain. Arch Gen Psychiatry 69: 904-912.
    • (2012) Arch Gen Psychiatry , vol.69 , pp. 904-912
    • Malhotra, A.K.1    Correll, C.U.2    Chowdhury, N.I.3    Müller, D.J.4    Gregersen, P.K.5    Lee, A.T.6
  • 33
    • 67649148483 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic response in the CATIE trial: A candidate gene analysis
    • Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP et al (2009). Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur J Hum Genet 17: 946-957.
    • (2009) Eur J Hum Genet , vol.17 , pp. 946-957
    • Need, A.C.1    Keefe, R.S.2    Ge, D.3    Grossman, I.4    Dickson, S.5    McEvoy, J.P.6
  • 34
    • 44349192747 scopus 로고    scopus 로고
    • Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers
    • Nussbaum J, Xu Q, Payne TJ, Ma JZ, Huang W, Gelernter J et al (2008). Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers. Hum Mol Genet 17: 1569-1577.
    • (2008) Hum Mol Genet , vol.17 , pp. 1569-1577
    • Nussbaum, J.1    Xu, Q.2    Payne, T.J.3    Ma, J.Z.4    Huang, W.5    Gelernter, J.6
  • 35
    • 84866657557 scopus 로고    scopus 로고
    • Implications of genetic findings for understanding schizophrenia
    • Owen MJ (2012). Implications of genetic findings for understanding schizophrenia. Schizophr Bull 38: 904-907.
    • (2012) Schizophr Bull , vol.38 , pp. 904-907
    • Owen, M.J.1
  • 36
    • 29644442521 scopus 로고    scopus 로고
    • Psychiatric genetics - The new era: Genetic research and some clinical implications
    • Prathikanti S, Weinberger DR (2005). Psychiatric genetics-the new era: genetic research and some clinical implications. Br Med Bull 73-74: 107-122.
    • (2005) Br Med Bull , vol.73 , Issue.74 , pp. 107-122
    • Prathikanti, S.1    Weinberger, D.R.2
  • 37
    • 84885020424 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 13 new risk loci for schizophrenia
    • Ripke, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE et al (2013). Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 45: 1150-1159.
    • (2013) Nat Genet , vol.45 , pp. 1150-1159
    • Ripke Chambert, K.1    Moran, J.L.2    Kähler, A.K.3    Akterin, S.4    Bergen, S.E.5
  • 38
    • 0036210068 scopus 로고    scopus 로고
    • Analysis of the human neurexin genes: Alternative splicing and the generation of protein diversity
    • Rowen L, Young J, Birditt B, Kaur A, Madan A, Philipps DL et al (2002). Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity. Genomics 79: 587-597.
    • (2002) Genomics , vol.79 , pp. 587-597
    • Rowen, L.1    Young, J.2    Birditt, B.3    Kaur, A.4    Madan, A.5    Philipps, D.L.6
  • 40
    • 70649088961 scopus 로고    scopus 로고
    • The peculiarities of large intron splicing in animals
    • Shepard S, McCreary M, Fedorov A (2009). The peculiarities of large intron splicing in animals. PLoS One 4: e7853.
    • (2009) PLoS One , vol.4
    • Shepard, S.1    McCreary, M.2    Fedorov, A.3
  • 41
    • 0019462450 scopus 로고
    • Dopamine receptors, neuroleptics, and schizophrenia
    • Snyder SH (1981). Dopamine receptors, neuroleptics, and schizophrenia. Am J Psychiatry 138: 460-464.
    • (1981) Am J Psychiatry , vol.138 , pp. 460-464
    • Snyder, S.H.1
  • 45
    • 54049091941 scopus 로고    scopus 로고
    • Neuroligins and neurexins link synaptic function to cognitive disease
    • Sudhof TC (2008). Neuroligins and neurexins link synaptic function to cognitive disease. Nature 455: 903-911.
    • (2008) Nature , vol.455 , pp. 903-911
    • Sudhof, T.C.1
  • 46
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • Sullivan PF, Daly MJ, O'Donovan M (2012). Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet 13: 537-551.
    • (2012) Nat Rev Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'donovan, M.3
  • 48
    • 84866687636 scopus 로고    scopus 로고
    • Analysis of copy number variation in Alzheimer's disease: The NIALOAD/ NCRAD Family Study
    • Swaminathan S, Shen L, Kim S, Inlow M, West JD, Faber KM et al (2012). Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study. Curr Alzheimer Res 9: 801-814.
    • (2012) Curr Alzheimer Res , vol.9 , pp. 801-814
    • Swaminathan, S.1    Shen, L.2    Kim, S.3    Inlow, M.4    West, J.D.5    Faber, K.M.6
  • 50
    • 0023215296 scopus 로고
    • Implications of normal brain development for the pathogenesis of schizophrenia
    • Weinberger DR (1987). Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 44: 660-669.
    • (1987) Arch Gen Psychiatry , vol.44 , pp. 660-669
    • Weinberger, D.R.1
  • 51
    • 77952720668 scopus 로고    scopus 로고
    • Neurexins physically and functionally interact with GABA(A) receptors
    • Zhang C, Atasoy D, Arac D, Yang X, Fucillo MV, Robison AJ et al (2010). Neurexins physically and functionally interact with GABA(A) receptors. Neuron 66: 403-416.
    • (2010) Neuron , vol.66 , pp. 403-416
    • Zhang, C.1    Atasoy, D.2    Arac, D.3    Yang, X.4    Fucillo, M.V.5    Robison, A.J.6
  • 52
    • 77954224633 scopus 로고    scopus 로고
    • D2 receptor genetic variation and clinical response to antipsychotic drug treatment: A meta-analysis
    • Zhang JP, Lencz T, Malhotra AK (2010). D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis. Am J Psychiatry 167: 763-772.
    • (2010) Am J Psychiatry , vol.167 , pp. 763-772
    • Zhang, J.P.1    Lencz, T.2    Malhotra, A.K.3


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