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Volumn 17, Issue 8, 2012, Pages 760-769

Pharmacogenetics in psychiatry: Translating research into clinical practice

Author keywords

antidepressants; antipsychotics; gene; pharmacogenetics; treatment

Indexed keywords

ANTIDEPRESSANT AGENT; CLOZAPINE; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; ESCITALOPRAM; NEUROLEPTIC AGENT; NORTRIPTYLINE; OLANZAPINE; PSYCHOTROPIC AGENT; RISPERIDONE; SEROTONIN UPTAKE INHIBITOR;

EID: 84864342355     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2011.146     Document Type: Review
Times cited : (68)

References (60)
  • 1
    • 34547469943 scopus 로고    scopus 로고
    • Pharmacogenetics and pharmacogenomics of schizophrenia: A review of last decade of research
    • DOI 10.1038/sj.mp.4002009, PII 4002009
    • Arranz MJ, de Leon J. Pharmacogenetics and pharmacogenomics of Schizophrenia: a review of last decade of research. Mol Psychiatry 2007; 12: 707-747. (Pubitemid 47172693)
    • (2007) Molecular Psychiatry , vol.12 , Issue.8 , pp. 707-747
    • Arranz, M.J.1    De Leon, J.2
  • 2
    • 78650472775 scopus 로고    scopus 로고
    • Pharmacogenetics and antipsychotics: Therapeutic efficacy and side effects prediction
    • Zhang JP, Malhotra AK. Pharmacogenetics and antipsychotics: therapeutic efficacy and side effects prediction. Expert Opin Drug Metab Toxicol 2011; 7: 9-37.
    • (2011) Expert Opin Drug Metab Toxicol , vol.7 , pp. 9-37
    • Zhang, J.P.1    Malhotra, A.K.2
  • 3
    • 77951844279 scopus 로고    scopus 로고
    • Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
    • Kato M, Serretti A. Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder. Mol Psychiatry 2010; 15: 473-500.
    • (2010) Mol Psychiatry , vol.15 , pp. 473-500
    • Kato, M.1    Serretti, A.2
  • 5
    • 85027952177 scopus 로고    scopus 로고
    • Cytochrome P450 testing for prescribing antipsychotics in adults with Schizophrenia: Systematic review and meta-analyses
    • Fleeman N, Dundar Y, Dickson R, Jorgensen A, Pushpakom S, McLeod C et al. Cytochrome P450 testing for prescribing antipsychotics in adults with Schizophrenia: systematic review and meta-analyses. Pharmacogenomics J 2011; 11: 1-14.
    • (2011) Pharmacogenomics J , vol.11 , pp. 1-14
    • Fleeman, N.1    Dundar, Y.2    Dickson, R.3    Jorgensen, A.4    Pushpakom, S.5    McLeod, C.6
  • 6
    • 77956170298 scopus 로고    scopus 로고
    • Antidepressant response and the serotonin transporter gene-Linked polymorphic region
    • Taylor MJ, Sen S, Bhagwagar Z. Antidepressant response and the serotonin transporter gene-Linked polymorphic region. Biol Psychiatry 2010; 68: 536-543.
    • (2010) Biol Psychiatry , vol.68 , pp. 536-543
    • Taylor, M.J.1    Sen, S.2    Bhagwagar, Z.3
  • 7
    • 78149321346 scopus 로고    scopus 로고
    • Pharmacogenetics of lithium response in bipolar disorder
    • McCarthy MJ, Leckband SG, Kelsoe Jr. Pharmacogenetics of lithium response in bipolar disorder. Pharmacogenomics 2010; 11: 1439-1465.
    • (2010) Pharmacogenomics , vol.11 , pp. 1439-1465
    • McCarthy, M.J.1    Leckband, S.G.2    Kelsoe, J.R.3
  • 9
    • 77954224633 scopus 로고    scopus 로고
    • D2 receptor genetic variation and clinical response to antipsychotic drug treatment: A meta-analysis
    • Zhang JP, Lencz T, Malhotra AK. D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis. Am J Psychiatry 2010; 167: 763-772.
    • (2010) Am J Psychiatry , vol.167 , pp. 763-772
    • Zhang, J.P.1    Lencz, T.2    Malhotra, A.K.3
  • 10
    • 33847257284 scopus 로고    scopus 로고
    • Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients
    • DOI 10.1038/sj.mp.4001926, PII 4001926
    • Serretti A, Kato M, De Ronchi D, Kinoshita T. Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with selective serotonin reuptake inhibitor efficacy in depressed patients. Mol Psychiatry 2007; 12: 247-257. (Pubitemid 46328503)
    • (2007) Molecular Psychiatry , vol.12 , Issue.3 , pp. 247-257
    • Serretti, A.1    Kato, M.2    De Ronchi, D.3    Kinoshita, T.4
  • 11
    • 0042357440 scopus 로고    scopus 로고
    • PM frequencies of major CYPs in Asians and Caucasians
    • Mizutani T. PM frequencies of major CYPs in Asians and Caucasians. Drug Metab Rev 2003; 35: 99-106. (Pubitemid 37048293)
    • (2003) Drug Metabolism Reviews , vol.35 , Issue.2-3 , pp. 99-106
    • Mizutani, T.1
  • 12
    • 0036378713 scopus 로고    scopus 로고
    • Comprehensive survey of the relationship between serum concentration and therapeutic effect of amitriptyline in depression
    • Ulrich S, Lauter J. Comprehensive survey of the relationship between serum concentration and therapeutic effect of amitriptyline in depression. Clin Pharmacokinet 2002; 41: 853-876.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 853-876
    • Ulrich, S.1    Lauter, J.2
  • 13
    • 0031980134 scopus 로고    scopus 로고
    • Optimizing treatment with clozapine
    • Conley RR. Optimizing treatment with clozapine. J Clin Psychiatry 1998; 59(Suppl 3): 44-48. (Pubitemid 28196370)
    • (1998) Journal of Clinical Psychiatry , vol.59 , Issue.SUPPL. 3 , pp. 44-48
    • Conley, R.R.1
  • 14
    • 29544449443 scopus 로고    scopus 로고
    • Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19
    • DOI 10.1176/appi.psy.47.1.75
    • de Leon J, Armstrong SC, Cozza KL. Clinical guidelines for psychiatrists for the use of pharmacogenetic testing for CYP450 2D6 and CYP450 2C19. Psychosomatics 2006; 47: 75-85. (Pubitemid 43017126)
    • (2006) Psychosomatics , vol.47 , Issue.1 , pp. 75-85
    • De Leon, J.1    Armstrong, S.C.2    Cozza, K.L.3
  • 15
    • 66149185456 scopus 로고    scopus 로고
    • Genomewide association studies: History, rationale, and prospects for psychiatric disorders
    • Cichon S, Craddock N, Daly M, Faraone SV, Gejman PV, Kelsoe J et al. Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry 2009; 166: 540-556.
    • (2009) Am J Psychiatry , vol.166 , pp. 540-556
    • Cichon, S.1    Craddock, N.2    Daly, M.3    Faraone, S.V.4    Gejman, P.V.5    Kelsoe, J.6
  • 16
    • 77951779878 scopus 로고    scopus 로고
    • Genome-wide pharmacogenetics of antidepressant response in the GENDEP project
    • Uher R, Perroud N, Ng MY, Hauser J, Henigsberg N, Maier Wet al. Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry 2010; 167: 555-564.
    • (2010) Am J Psychiatry , vol.167 , pp. 555-564
    • Uher, R.1    Perroud, N.2    Ng, M.Y.3    Hauser, J.4    Henigsberg, N.5    Maier, W.6
  • 18
    • 69949184308 scopus 로고    scopus 로고
    • A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression
    • Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry 2009; 66: 966-975.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 966-975
    • Ising, M.1    Lucae, S.2    Binder, E.B.3    Bettecken, T.4    Uhr, M.5    Ripke, S.6
  • 19
    • 66949165513 scopus 로고    scopus 로고
    • A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder
    • Perlis RH, Smoller JW, Ferreira MA, McQuillin A, Bass N, Lawrence J et al. A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry 2009; 166: 718-725.
    • (2009) Am J Psychiatry , vol.166 , pp. 718-725
    • Perlis, R.H.1    Smoller, J.W.2    Ferreira, M.A.3    McQuillin, A.4    Bass, N.5    Lawrence, J.6
  • 21
    • 79951813616 scopus 로고    scopus 로고
    • Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs
    • Adkins DE, Aberg K, McClay JL, Bukszár J, Zhao Z, Jia P et al. Genomewide pharmacogenomic study of metabolic side effects to antipsychotic drugs. Mol Psychiatry 2011; 16: 321-332.
    • (2011) Mol Psychiatry , vol.16 , pp. 321-332
    • Adkins, D.E.1    Aberg, K.2    McClay, J.L.3    Bukszár, J.4    Zhao, Z.5    Jia, P.6
  • 22
    • 70349574008 scopus 로고    scopus 로고
    • Genomewide association study of antipsychotic-induced parkinsonism severity among Schizophrenia patients
    • Alkelai A, Greenbaum L, Rigbi A, Kanyas K, Lerer B. Genomewide association study of antipsychotic-induced parkinsonism severity among Schizophrenia patients. Psychopharmacology (Berl) 2009; 206: 491-499.
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 491-499
    • Alkelai, A.1    Greenbaum, L.2    Rigbi, A.3    Kanyas, K.4    Lerer, B.5
  • 24
    • 77957724588 scopus 로고    scopus 로고
    • Science and regulation. Regulating direct-to-consumer personal genome testing
    • McGuire AL, Evans BJ, Caulfield T, Burke W. Science and regulation. Regulating direct-to-consumer personal genome testing. Science (New York, NY) 2010; 330: 181-182.
    • (2010) Science (New York, NY) , vol.330 , pp. 181-182
    • McGuire, A.L.1    Evans, B.J.2    Caulfield, T.3    Burke, W.4
  • 26
    • 57649139354 scopus 로고    scopus 로고
    • Pharmacogenomics: The promise of personalized medicine for CNS disorders
    • de Leon J. Pharmacogenomics: the promise of personalized medicine for CNS disorders. Neuropsychopharmacology 2009; 34: 159-172.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 159-172
    • De Leon, J.1
  • 27
    • 34848907418 scopus 로고    scopus 로고
    • Genomics and the future of pharmacotherapy in psychiatry
    • DOI 10.1080/09540260701563460, PII 782452476
    • Malhotra AK, Lencz T, Correll CU, Kane JM. Genomics and the future of pharmacotherapy in psychiatry. Int Rev Psychiatry (Abingdon, England) 2007; 19: 523-530. (Pubitemid 47493739)
    • (2007) International Review of Psychiatry , vol.19 , Issue.5 , pp. 523-530
    • Malhotra, A.K.1    Lencz, T.2    Correll, C.U.3    Kane, J.M.4
  • 28
    • 0037712923 scopus 로고    scopus 로고
    • Atypical and conventional antipsychotic drugs in treatment-naive first-episode Schizophrenia: A 52-week randomized trial of clozapine vs chlorpromazine
    • Lieberman JA, Phillips M, Gu H, Stroup S, Zhang P, Kong L et al. Atypical and conventional antipsychotic drugs in treatment-naive first-episode Schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine. Neuropsychopharmacology 2003; 28: 995-1003.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 995-1003
    • Lieberman, J.A.1    Phillips, M.2    Gu, H.3    Stroup, S.4    Zhang, P.5    Kong, L.6
  • 30
    • 0034656321 scopus 로고    scopus 로고
    • Penny-wise and pound-foolish: The impact of measurement error on sample size requirements in clinical trials
    • DOI 10.1016/S0006-3223(00)00837-4, PII S0006322300008374
    • Perkins DO, Wyatt RJ, Bartko JJ. Penny-wise and pound-foolish: the impact of measurement error on sample size requirements in clinical trials. Biol Psychiatry 2000; 47: 762-766. (Pubitemid 30201674)
    • (2000) Biological Psychiatry , vol.47 , Issue.8 , pp. 762-766
    • Perkins, D.O.1    Wyatt, R.J.2    Bartko, J.J.3
  • 31
    • 67649859295 scopus 로고    scopus 로고
    • HLA-B*5701 genotype is a major determinant of druginduced liver injury due to flucloxacillin
    • Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A et al. HLA-B*5701 genotype is a major determinant of druginduced liver injury due to flucloxacillin. Nat Genet 2009; 41: 816-819.
    • (2009) Nat Genet , vol.41 , pp. 816-819
    • Daly, A.K.1    Donaldson, P.T.2    Bhatnagar, P.3    Shen, Y.4    Pe'Er, I.5    Floratos, A.6
  • 33
    • 77949600882 scopus 로고    scopus 로고
    • Common risk allele in aromatic antiepileptic-drug induced stevens-johnson syndrome and toxic epidermal necrolysis in han chinese
    • Hung SI, Chung WH, Liu ZS, Chen CH, Hsih MS, Hui RC et al. Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. Pharmacogenomics 2010; 11: 349-356.
    • (2010) Pharmacogenomics , vol.11 , pp. 349-356
    • Hung, S.I.1    Chung, W.H.2    Liu, Z.S.3    Chen, C.H.4    Hsih, M.S.5    Hui, R.C.6
  • 34
    • 70249102418 scopus 로고    scopus 로고
    • High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients
    • Kazeem GR, Cox C, Aponte J, Messenheimer J, Brazell C, Nelsen AC et al. High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients. Pharmacogenet Genomics 2009; 19: 661-665.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 661-665
    • Kazeem, G.R.1    Cox, C.2    Aponte, J.3    Messenheimer, J.4    Brazell, C.5    Nelsen, A.C.6
  • 35
    • 0023812652 scopus 로고
    • Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine
    • Kane J, Honigfeld G, Singer J, Meltzer H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45: 789-796.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 789-796
    • Kane, J.1    Honigfeld, G.2    Singer, J.3    Meltzer, H.4
  • 38
    • 79955508661 scopus 로고    scopus 로고
    • Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis
    • Athanasiou MC, Dettling M, Cascorbi I, Mosyagin I, Salisbury BA, Pierz KA et al. Candidate gene analysis identifies a polymorphism in HLA-DQB1 associated with clozapine-induced agranulocytosis. J Clin Psychiatry 2011; 72: 458-463.
    • (2011) J Clin Psychiatry , vol.72 , pp. 458-463
    • Athanasiou, M.C.1    Dettling, M.2    Cascorbi, I.3    Mosyagin, I.4    Salisbury, B.A.5    Pierz, K.A.6
  • 39
    • 64749101027 scopus 로고    scopus 로고
    • Weight effects associated with antipsychotics: A comprehensive database analysis
    • Parsons B, Allison DB, Loebel A, Williams K, Giller E, Romano S et al. Weight effects associated with antipsychotics: a comprehensive database analysis. Schizophr Res 2009; 110: 103-110.
    • (2009) Schizophr Res , vol.110 , pp. 103-110
    • Parsons, B.1    Allison, D.B.2    Loebel, A.3    Williams, K.4    Giller, E.5    Romano, S.6
  • 42
    • 55749083565 scopus 로고    scopus 로고
    • Double-blind comparison of first-and second-generation antipsychotics in early-onset Schizophrenia and schizo-affective disorder: Findings from the treatment of early-onset Schizophrenia spectrum disorders (TEOSS) study
    • Sikich L, Frazier JA, McClellan J, Findling RL, Vitiello B, Ritz L et al. Double-blind comparison of first-and second-generation antipsychotics in early-onset Schizophrenia and schizo-affective disorder: findings from the treatment of early-onset Schizophrenia spectrum disorders (TEOSS) study. Am J Psychiatry 2008; 165: 1420-1431.
    • (2008) Am J Psychiatry , vol.165 , pp. 1420-1431
    • Sikich, L.1    Frazier, J.A.2    McClellan, J.3    Findling, R.L.4    Vitiello, B.5    Ritz, L.6
  • 43
    • 70350738289 scopus 로고    scopus 로고
    • Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents
    • Correll CU, Manu P, Olshanskiy V, Napolitano B, Kane JM, Malhotra AK. Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA 2009; 302: 1765-1773.
    • (2009) JAMA , vol.302 , pp. 1765-1773
    • Correll, C.U.1    Manu, P.2    Olshanskiy, V.3    Napolitano, B.4    Kane, J.M.5    Malhotra, A.K.6
  • 44
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • DOI 10.1016/S0140-6736(02)08913-4
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet 2002; 359: 2086-2087. (Pubitemid 34680975)
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.-J.2    Zhang, X.-B.3
  • 45
    • 17644394540 scopus 로고    scopus 로고
    • Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis
    • Templeman LA, Reynolds GP, Arranz B, San L. Polymorphisms of the 5-HT2C receptor and leptin genes are associated with antipsychotic drug-induced weight gain in Caucasian subjects with a first-episode psychosis. Pharmacogenet Genomics 2005; 15: 195-200. (Pubitemid 40569890)
    • (2005) Pharmacogenetics and Genomics , vol.15 , Issue.4 , pp. 195-200
    • Templeman, L.A.1    Reynolds, G.P.2    Arranz, B.3    San, L.4
  • 46
    • 78649711976 scopus 로고    scopus 로고
    • Polymorphisms of the htr2c gene and antipsychoticinduced weight gain: An update and meta-analysis
    • Sicard MN, Zai CC, Tiwari AK, Souza RP, Meltzer HY, Lieberman JA et al. Polymorphisms of the HTR2C gene and antipsychoticinduced weight gain: an update and meta-analysis. Pharmacogenomics 2010; 11: 1561-1571.
    • (2010) Pharmacogenomics , vol.11 , pp. 1561-1571
    • Sicard, M.N.1    Zai, C.C.2    Tiwari, A.K.3    Souza, R.P.4    Meltzer, H.Y.5    Lieberman, J.A.6
  • 47
    • 77955919157 scopus 로고    scopus 로고
    • DRD2 promoter region variation predicts antipsychoticinduced weight gain in first episode Schizophrenia
    • Lencz T, Robinson DG, Napolitano B, Sevy S, Kane JM, Goldman D et al. DRD2 promoter region variation predicts antipsychoticinduced weight gain in first episode Schizophrenia. Pharmacogenet Genomics 2010; 20: 569-572.
    • (2010) Pharmacogenet Genomics , vol.20 , pp. 569-572
    • Lencz, T.1    Robinson, D.G.2    Napolitano, B.3    Sevy, S.4    Kane, J.M.5    Goldman, D.6
  • 48
    • 67650105447 scopus 로고    scopus 로고
    • Medication adherence: A review of the literature and implications for clinical practice
    • Julius RJ, Novitsky Jr MA, Dubin WR. Medication adherence: a review of the literature and implications for clinical practice. J Psychiatr Pract 2009; 15: 34-44.
    • (2009) J Psychiatr Pract , vol.15 , pp. 34-44
    • Julius, R.J.1    Novitsky Jr., M.A.2    Dubin, W.R.3
  • 49
    • 84864360977 scopus 로고    scopus 로고
    • Enhancing power in pharmacogenetic studies: Maximizing adherence and meta-analytic strategies. Symposium
    • Presented at the San Francisco, CA, 13th May
    • Zhang JP, Lencz T, Malhotra AK. Enhancing power in pharmacogenetic studies: maximizing adherence and meta-analytic strategies. Symposium Presented at the Society of Biological Psychiatry Annual Meeting. San Francisco, CA, 13th May 2011.
    • (2011) Society of Biological Psychiatry Annual Meeting
    • Zhang, J.P.1    Lencz, T.2    Malhotra, A.K.3
  • 50
    • 70349285147 scopus 로고    scopus 로고
    • The expert consensus guideline series: Adherence problems in patients with serious and persistent mental illness
    • quiz 47-48
    • Velligan DI, Weiden PJ, Sajatovic M, Scott J, Carpenter D, Ross R et al. The expert consensus guideline series: adherence problems in patients with serious and persistent mental illness. J Clin Psychiatry 2009; 70(Suppl 4): 1-46; quiz 47-48.
    • (2009) J Clin Psychiatry , vol.70 , Issue.SUPPL. 4 , pp. 1-46
    • Velligan, D.I.1    Weiden, P.J.2    Sajatovic, M.3    Scott, J.4    Carpenter, D.5    Ross, R.6
  • 51
    • 77957914609 scopus 로고    scopus 로고
    • The psychiatric GWAS consortium: Big science comes to psychiatry
    • Sullivan PF. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron 2010; 68: 182-186.
    • (2010) Neuron , vol.68 , pp. 182-186
    • Sullivan, P.F.1
  • 54
    • 78049326068 scopus 로고    scopus 로고
    • Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
    • Mega JL, Simon T, Collet JP, Anderson JL, Antman EM, Bliden K et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 2010; 304: 1821-1830.
    • (2010) JAMA , vol.304 , pp. 1821-1830
    • Mega, J.L.1    Simon, T.2    Collet, J.P.3    Anderson, J.L.4    Antman, E.M.5    Bliden, K.6
  • 56
    • 78649726626 scopus 로고    scopus 로고
    • Personalized medicine for depression: Can we match patients with treatments?
    • Simon GE, Perlis RH. Personalized medicine for depression: can we match patients with treatments? Am J Psychiatry 2010; 167: 1445-1455.
    • (2010) Am J Psychiatry , vol.167 , pp. 1445-1455
    • Simon, G.E.1    Perlis, R.H.2
  • 57
    • 79952711338 scopus 로고    scopus 로고
    • Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking
    • Johnson BA, Ait-Daoud N, Seneviratne C, Roache JD, Javors MA, Wang XQ et al. Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking. Am J Psychiatry 2011; 168: 265-275.
    • (2011) Am J Psychiatry , vol.168 , pp. 265-275
    • Johnson, B.A.1    Ait-Daoud, N.2    Seneviratne, C.3    Roache, J.D.4    Javors, M.A.5    Wang, X.Q.6
  • 58
    • 23844516328 scopus 로고    scopus 로고
    • Pharmacogenetics-based therapeutic recommendations - Ready for clinical practice?
    • DOI 10.1038/nrd1801
    • Kirchheiner J, Fuhr U, Brockmoller J. Pharmacogenetics-based therapeutic recommendations-ready for clinical practice? Nat Rev Drug Discov 2005; 4: 639-647. (Pubitemid 41149757)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.8 , pp. 639-647
    • Kirchheiner, J.1    Fuhr, U.2    Brockmoller, J.3
  • 59
    • 38049185136 scopus 로고    scopus 로고
    • Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: A randomized controlled trial
    • Wu RR, Zhao JP, Jin H, Shao P, Fang MS, Guo XF et al. Lifestyle intervention and metformin for treatment of antipsychotic-induced weight gain: a randomized controlled trial. JAMA 2008; 299: 185-193.
    • (2008) JAMA , vol.299 , pp. 185-193
    • Wu, R.R.1    Zhao, J.P.2    Jin, H.3    Shao, P.4    Fang, M.S.5    Guo, X.F.6
  • 60
    • 49849105411 scopus 로고    scopus 로고
    • Laboratory and clinical outcomes of pharmacogenetic vs. Clinical protocols for warfarin initiation in orthopedic patients
    • Lenzini PA, Grice GR, Milligan PE, Dowd MB, Subherwal S, Deych E et al. Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedic patients. J Thromb Haemost 2008; 6: 1655-1662.
    • (2008) J Thromb Haemost , vol.6 , pp. 1655-1662
    • Lenzini, P.A.1    Grice, G.R.2    Milligan, P.E.3    Dowd, M.B.4    Subherwal, S.5    Deych, E.6


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