Folin-Ciocalteu spectrophotometric assay of ascorbic acid in pharmaceutical tablets and orange juice with pH adjustment and pre-extraction of lanthanum(III)-flavonoid complexes

Journal of the Science of Food and Agriculture

Volumn 94, Issue 12, 2014, Pages 2401-2408

  Olgun, Ayca Ozdemir ^a   Ozyurt, Dilek ^a   Berker, Kadriye Isil ^a   Demirata, Birsen ^a   Apak, Resat ^b  

^a ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Ascorbic acid assay; La(III) chelate extraction; Modified Folin Ciocalteu method; Polyphenol removal; Spectrophotometry

Indexed keywords

ANTIOXIDANT; ASCORBIC ACID; BUTANOL; CHELATING AGENT; DRUG; FLAVONOID; ION; ISOBUTANOL; LANTHANUM; PHENOL DERIVATIVE; TABLET;

ANALYSIS; BEVERAGE; CHEMICAL PHENOMENA; CHEMISTRY; HUMAN; OXIDATION REDUCTION REACTION; PH; PROCEDURES; REPRODUCIBILITY; SPECTROPHOTOMETRY; SWEET ORANGE; TABLET; VALIDATION STUDY;

ANTIOXIDANTS; ASCORBIC ACID; BEVERAGES; BUTANOLS; CHELATING AGENTS; CITRUS SINENSIS; FLAVONOIDS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IONS; LANTHANUM; OXIDATION-REDUCTION; PHARMACEUTICAL PREPARATIONS; PHENOLS; REPRODUCIBILITY OF RESULTS; SPECTROPHOTOMETRY; TABLETS;

EID: 84904406719     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.6569     Document Type: Article

References (29)

1. Kukoc-Modun L, Biocic M and Radic N, Indirect method for spectrophotometric determination of ascorbic acid in pharmaceutical preparations with 2, 4, 6-tripyridyl-s-triazine by flow-injection analysis. Talanta 96:174-179 (2012).
2. Shyla B and Nagendrappa G, Redox spectrophotometric method involving electrolytically generated manganese(III) sulphate with diphenylamine for the determination of ascorbic acid present in the samples of various fruits, commercial juices and sprouted food grains. Food Chem 138:2036-2042 (2013).
3. Deng P, Xu Z and Li J, Simultaneous determination of ascorbic acid and rutin in pharmaceutical preparations with electrochemical method based on multi-walled carbon nanotubes-chitosan composite film modified electrode. J Pharm Biomed Anal 76:234-242 (2013).
4. Tang B, Wang Y, Du M, GE J and Chen Z, Catalytic spectrophotometric determination of ascorbic acid in tea drink with 1, 5-bis(p-hydroxybenzaldene) thiocarbohydrazone as the substrate for horseradish peroxidase. J Agric Food Chem 51:4198-4201 (2003).
5. Davies SHR and Masten SJ, Spectrophotometric method for ascorbic acid using dichlorophenolindophenol: Elimination of the interference due to iron. Anal Chim Acta 248:225-227 (1991).
6. Güçlü K, Sözgen K, Tütem E, Özyürek M and Apak R, Spectrophotometric determination of ascorbic acid using copper(II)-neocuproine reagent in beverages and pharmaceuticals. Talanta 65:1226-1232 (2005).
7. Shieh HH and Sweet TR, Spectrophotometric determination of ascorbic acid. Anal Biochem 96:1-5 (1979).
8. Association of Official Analytical Chemists, Official Methods of Analysis of the Association of Official Analytical Chemists, 10th edition, ed. by Horwitz W. AOAC, Washington DC (1965).
9. Ranganna S, Manual of Analysis of Fruit and Vegetable Products. Tata McGraw-Hill, New Delhi (1977).
10. Kozar S, Bujak A, Eder-Trifunovic J and Kniewald G, Determination of L-ascorbic acid in fresh and processed fruit and vegetables by differential pulse polarography. Fresenius Z Anal Chem 329:760-763 (1988).
11. Lourençao BC, Medeiros RA, Rocha-Filho RC and Fatibello-Filho O, Simultaneous differential pulse voltammetric determination of ascorbic acid and caffeine in pharmaceutical formulations using a boron-doped diamond electrode. Electroanalysis 22:1717-1723 (2010).
12. Pandey NK, Spectrophotometric and titrimetric determinations of ascorbic acid. Anal Chem 54:793-798 (1982).
13. Esteve MJ, Farre R, Frigola A, Lopez JC, Romera JM, Ramirez M, et al., Comparison of voltammetric and high-performance liquid-chromatographic methods for ascorbic-acid determination in infant formulas. Food Chem 52:99-102 (1995).
14. Lau OW, Shiu KK and Chang ST, Determination of ascorbic acid in vegetables and fruits by differential pulse polarography. J Sci Food Agric 36:733-739 (1985).
15. Wu X, Diao Y, Sun C, Yang J, Wang Y and Sun S, Fluorimetric determination of ascorbic acid with o-phenylenediamine. Talanta 59:95-99 (2003).
16. Novakova L, Solich P and Solichova D, HPLC methods for simultaneous determination of ascorbic and dehydroascorbic acids. Trends Anal Chem 27:942-958 (2008).
17. Fenoll J, Martinez A, Hellin P and Flores P, Simultaneous determination of ascorbic and dehydroascorbic acids in vegetables and fruits by liquid chromatography with tandem-mass spectrometry. Food Chem 127:340-344 (2011).
18. Kand'ár R, Drábková P and Hampl R, The determination of ascorbic acid and uric acid in human seminal plasma using an HPLC with UV detection. J Chromatogr B 879:2834-2839 (2011).
19. Maki T, Soh N, Nakano K and Imato T, Flow injection fluorometric determination of ascorbic acid using perylenebisimide-linked nitroxide. Talanta 85:1730-1733 (2011).
20. Berker KI, Olgun FAO, Ozyurt D, Demirata B and Apak R, Modified Folin-Ciocalteu antioxidant capacity assay for measuring lipophilic antioxidants. J Agric Food Chem 61:4783-4791 (2013).
21. Singleton VL, Orthofer R and Lamuela-Raventos RM, Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol 299:152-178 (1999).
22. Ozyurek M, Guclu K, Bektasoglu B and Apak R, Spectrophotometric determination of ascorbic acid by the modified CUPRAC method with extractive separation of flavonoids-La(III) complexes. Anal Chim Acta 588:88-95 (2007).
23. Lykkesfeldt J, Loft S and Poulsen HE, Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection - are they reliable biomarkers of oxidative stress? Anal Biochem 229:329-335 (1995).
24. Long GL and Winefordner JD, Limit of detection: A closer look at the IUPAC definition. Anal Chem 55:712A-724A (1983).
25. Hewitt EJ and Dickes GJ, Spectrophotometric measurements on ascorbic acid and their use for the estimation of ascorbic acid and dehydroascorbic acid in plant tissues. Biochem J 78:384-391 (1961).
26. Isabelle M, Lee BL, Lim MT, Koh W-P, Huang D and Ong CN, Antioxidant activity and profiles of common vegetables in Singapore. Food Chem 120:993-1003 (2010).
27. Ford BL, Bai J, Manthey J and Baldwin EA, Improved removal of ascorbate interference in the Folin-Ciocalteu assay of 'total phenolic content'. Proc Florida State Hort Soc 123:220-222 (2010).
28. Sanchez-Rangel JC, Benavides J, Heredia JB, Cisneros-Zevallos L and Jacobo-Velazquez DA, The Folin-Ciocalteu assay revisited: Improvement of its specificity for total phenolic content determination. Anal Methods 5:5990-5999 (2013).
29. George S, Brat P, Alter P and Amiot MJ, Rapid determination of polyphenols and vitamin C in plant-derived products. J Agric Food Chem 53:1370-1373 (2005).