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Volumn 2, Issue 1, 2014, Pages 16-20

Field cancerization in the colon: A role for aberrant DNA methylation?

Author keywords

Colorectal cancer; DNA methylation; Epigenetic alterations; Field cancerization

Indexed keywords


EID: 84904393925     PISSN: None     EISSN: 20520034     Source Type: Journal    
DOI: 10.1093/gastro/got039     Document Type: Review
Times cited : (41)

References (44)
  • 1
    • 72449176846 scopus 로고    scopus 로고
    • Molecular origins of cancer: Molecular basis of colorectal cancer
    • Markowitz SD and Bertagnolli MM. Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 2009;361: 2449-60.
    • (2009) N Engl J Med , vol.361 , pp. 2449-2460
    • Markowitz, S.D.1    Bertagnolli, M.M.2
  • 2
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM and Carethers JM. Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 2008;135: 1079-99.
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 4
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; Clinical implications of multicentric origin
    • Slaughter DP, Southwick HW and Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953;6:963-68.
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 5
    • 38349026288 scopus 로고    scopus 로고
    • Field defects in progression to gastrointestinal tract cancers
    • Bernstein C, Bernstein H, Payne CM et al. Field defects in progression to gastrointestinal tract cancers. Cancer Lett 2008;260:1-10.
    • (2008) Cancer Lett , vol.260 , pp. 1-10
    • Bernstein, C.1    Bernstein, H.2    Payne, C.M.3
  • 6
    • 84872145972 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: Special situations
    • Van Assche G, Dignass A, Bokemeyer B et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations. J Crohns Colitis 2013;7: 1-33.
    • (2013) J Crohns Colitis , vol.7 , pp. 1-33
    • Van Assche, G.1    Dignass, A.2    Bokemeyer, B.3
  • 7
    • 84861338028 scopus 로고    scopus 로고
    • Development of ulcerative colitis and its associated colorectal neoplasia as a model of the organ-specific chronic inflammation-carcinoma sequence
    • Okayasu I. Development of ulcerative colitis and its associated colorectal neoplasia as a model of the organ-specific chronic inflammation-carcinoma sequence. Pathol Int 2012;62:368-80.
    • (2012) Pathol Int , vol.62 , pp. 368-380
    • Okayasu, I.1
  • 8
    • 84873412849 scopus 로고    scopus 로고
    • Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development
    • Azer SA. Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development. Eur J Gastroenterol Hepatol 2013;25:271-81.
    • (2013) Eur J Gastroenterol Hepatol , vol.25 , pp. 271-281
    • Azer, S.A.1
  • 9
    • 84859393237 scopus 로고    scopus 로고
    • Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis
    • e8
    • Galandiuk S, Rodriguez-Justo M, Jeffery R et al. Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis. Gastroenterology 2012;142:855-864, e8.
    • (2012) Gastroenterology , vol.142 , pp. 855-864
    • Galandiuk, S.1    Rodriguez-Justo, M.2    Jeffery, R.3
  • 10
    • 84873095994 scopus 로고    scopus 로고
    • High constant incidence of second primary colorectal cancer
    • Levi F, Randimbison L, Blanc-Moya R et al. High constant incidence of second primary colorectal cancer. Int J Cancer 2013;132:1679-82.
    • (2013) Int J Cancer , vol.132 , pp. 1679-1682
    • Levi, F.1    Randimbison, L.2    Blanc-Moya, R.3
  • 11
    • 84900832822 scopus 로고    scopus 로고
    • Evidence for field effect cancerization in colorectal cancer
    • Dec 3. [Epub ahead of print]
    • Hawthorn L, Lan L and Mojica W. Evidence for field effect cancerization in colorectal cancer. Genomics 2013 Dec 3. [Epub ahead of print].
    • (2013) Genomics
    • Hawthorn, L.1    Lan, L.2    Mojica, W.3
  • 13
    • 77949656675 scopus 로고    scopus 로고
    • DNA methylation within the normal colorectal mucosa is associated with pathwayspecific predisposition to cancer
    • Worthley DL, Whitehall VL, Buttenshaw RL et al. DNA methylation within the normal colorectal mucosa is associated with pathwayspecific predisposition to cancer. Oncogene 2010;29:1653-62.
    • (2010) Oncogene , vol.29 , pp. 1653-1662
    • Worthley, D.L.1    Whitehall, V.L.2    Buttenshaw, R.L.3
  • 14
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird A. The essentials of DNA methylation. Cell 1992;70:5-8.
    • (1992) Cell , vol.70 , pp. 5-8
    • Bird, A.1
  • 15
    • 13144307115 scopus 로고    scopus 로고
    • Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
    • Veigl M, Kasturi L, Olechnowicz J et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Nat Acad Sci USA 1998;95:8698-702.
    • (1998) Proc Nat Acad Sci USA , vol.95 , pp. 8698-8702
    • Veigl, M.1    Kasturi, L.2    Olechnowicz, J.3
  • 16
    • 0034723255 scopus 로고    scopus 로고
    • Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression
    • Graff JR, Gabrielson E, Fujii H et al. Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression. J Biol Chem 2000;275:2727-32.
    • (2000) J Biol Chem , vol.275 , pp. 2727-2732
    • Graff, J.R.1    Gabrielson, E.2    Fujii, H.3
  • 17
    • 0034807280 scopus 로고    scopus 로고
    • Methylation and colorectal cancer
    • Jubb AM, Bell SM and Quirke P. Methylation and colorectal cancer. J Pathol 2001;195:111-34.
    • (2001) J Pathol , vol.195 , pp. 111-134
    • Jubb, A.M.1    Bell, S.M.2    Quirke, P.3
  • 18
    • 33745714364 scopus 로고    scopus 로고
    • CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer
    • Kim YH, Petko Z, Dzieciatkowski S et al. CpG island methylation of genes accumulates during the adenoma progression step of the multistep pathogenesis of colorectal cancer. Genes Chromosomes Cancer 2006;45:781-89.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 781-789
    • Kim, Y.H.1    Petko, Z.2    Dzieciatkowski, S.3
  • 19
    • 25144518262 scopus 로고    scopus 로고
    • MGMT promoter methylation and field defect in sporadic colorectal cancer
    • Shen L, Kondo Y, Rosner GL et al. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst 2005;97:1330-38.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1330-1338
    • Shen, L.1    Kondo, Y.2    Rosner, G.L.3
  • 20
    • 0032401808 scopus 로고    scopus 로고
    • Aging and DNA methylation in colorectal mucosa and cancer
    • Ahuja N, Li Q, Mohan M et al. Aging and DNA methylation in colorectal mucosa and cancer. Cancer Res 1998;58:5489-94.
    • (1998) Cancer Res , vol.58 , pp. 5489-5494
    • Ahuja, N.1    Li, Q.2    Mohan, M.3
  • 21
    • 32944459562 scopus 로고    scopus 로고
    • High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
    • Maekita T, Nakazawa K, Mihara M et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin Cancer Res 2006;12:989-95.
    • (2006) Clin Cancer Res , vol.12 , pp. 989-995
    • Maekita, T.1    Nakazawa, K.2    Mihara, M.3
  • 22
    • 0034847481 scopus 로고    scopus 로고
    • CpG island methylation in colorectal adenomas
    • Rashid A, Shen L, Morris JS et al. CpG island methylation in colorectal adenomas. Am J Pathol 2001;159:1129-35.
    • (2001) Am J Pathol , vol.159 , pp. 1129-1135
    • Rashid, A.1    Shen, L.2    Morris, J.S.3
  • 23
    • 0037446974 scopus 로고    scopus 로고
    • A genetic explanation of Slaughter's concept of field cancerization: Evidence and clinical implications
    • Braakhuis BJ, Tabor MP, Kummer JA et al. A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications. Cancer Res 2003;63:1727-30.
    • (2003) Cancer Res , vol.63 , pp. 1727-1730
    • Braakhuis, B.J.1    Tabor, M.P.2    Kummer, J.A.3
  • 24
    • 71049128283 scopus 로고    scopus 로고
    • Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colon
    • Hiraoka S, Kato J, Horii J et al. Methylation status of normal background mucosa is correlated with occurrence and development of neoplasia in the distal colon. Hum Pathol 41:38-47.
    • Hum Pathol , vol.41 , pp. 38-47
    • Hiraoka, S.1    Kato, J.2    Horii, J.3
  • 25
    • 33344467235 scopus 로고    scopus 로고
    • DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer
    • Kawakami K, Ruszkiewicz A, Bennett G et al. DNA hypermethylation in the normal colonic mucosa of patients with colorectal cancer. Br J Cancer 2006;94:593-98.
    • (2006) Br J Cancer , vol.94 , pp. 593-598
    • Kawakami, K.1    Ruszkiewicz, A.2    Bennett, G.3
  • 26
    • 77953942118 scopus 로고    scopus 로고
    • Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa
    • Belshaw NJ, Pal N, Tapp HS et al. Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa. Carcinogenesis 2010;31:1158-63.
    • (2010) Carcinogenesis , vol.31 , pp. 1158-1163
    • Belshaw, N.J.1    Pal, N.2    Tapp, H.S.3
  • 27
    • 0037372967 scopus 로고    scopus 로고
    • P14 methylation in human colon cancer is associated with microsatellite instability and wildtype p53
    • Shen L, Kondo Y, Hamilton SR et al. P14 methylation in human colon cancer is associated with microsatellite instability and wildtype p53. Gastroenterology 2003;124:626-33.
    • (2003) Gastroenterology , vol.124 , pp. 626-633
    • Shen, L.1    Kondo, Y.2    Hamilton, S.R.3
  • 28
    • 44449125989 scopus 로고    scopus 로고
    • Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer
    • Grady WM, Parkin RK, Mitchell PS et al. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene 2008;27:3880-88.
    • (2008) Oncogene , vol.27 , pp. 3880-3888
    • Grady, W.M.1    Parkin, R.K.2    Mitchell, P.S.3
  • 29
    • 46349091799 scopus 로고    scopus 로고
    • Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa
    • Belshaw NJ, Elliott GO, Foxall RJ et al. Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa. Br J Cancer 2008;99:136-42.
    • (2008) Br J Cancer , vol.99 , pp. 136-142
    • Belshaw, N.J.1    Elliott, G.O.2    Foxall, R.J.3
  • 30
    • 77957576132 scopus 로고    scopus 로고
    • Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas
    • Paun BC, Kukuruga D, Jin Z et al. Relation between normal rectal methylation, smoking status, and the presence or absence of colorectal adenomas. Cancer 2010;116:4495-501.
    • (2010) Cancer , vol.116 , pp. 4495-4501
    • Paun, B.C.1    Kukuruga, D.2    Jin, Z.3
  • 31
    • 84870552726 scopus 로고    scopus 로고
    • DNA demethylation in normal colon tissue predicts predisposition to multiple cancers
    • Kamiyama H, Suzuki K, Maeda T et al. DNA demethylation in normal colon tissue predicts predisposition to multiple cancers. Oncogene 2012;31:5029-37.
    • (2012) Oncogene , vol.31 , pp. 5029-5037
    • Kamiyama, H.1    Suzuki, K.2    Maeda, T.3
  • 32
    • 0033547330 scopus 로고    scopus 로고
    • Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methylatransferase gene
    • Xu G, Bestor T, Bourc'his D et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNa methylatransferase gene. Nature 1999;402:187-89.
    • (1999) Nature , vol.402 , pp. 187-189
    • Xu, G.1    Bestor, T.2    Bourc'his, D.3
  • 33
    • 66649109098 scopus 로고    scopus 로고
    • Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors
    • Figueiredo JC, Grau MV, Wallace K et al. Global DNA hypomethylation (LINE-1) in the normal colon and lifestyle characteristics and dietary and genetic factors. Cancer Epidemiol Biomarkers Prev 2009;18:1041-49.
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 1041-1049
    • Figueiredo, J.C.1    Grau, M.V.2    Wallace, K.3
  • 34
    • 78650352867 scopus 로고    scopus 로고
    • Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa
    • Wallace K, Grau MV, Levine AJ et al. Association between folate levels and CpG Island hypermethylation in normal colorectal mucosa. Cancer Prev Res (Phila) 2010;3:1552-64.
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 1552-1564
    • Wallace, K.1    Grau, M.V.2    Levine, A.J.3
  • 35
    • 4143132121 scopus 로고    scopus 로고
    • Promoter hypermethylation of resected bronchial margins: A field defect of changes?
    • Guo M, House MG, Hooker C et al. Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res 2004;10:5131-36.
    • (2004) Clin Cancer Res , vol.10 , pp. 5131-5136
    • Guo, M.1    House, M.G.2    Hooker, C.3
  • 36
    • 33845333815 scopus 로고    scopus 로고
    • Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue
    • Yan PS, Venkataramu C, Ibrahim A et al. Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clin Cancer Res 2006;12:6626-36.
    • (2006) Clin Cancer Res , vol.12 , pp. 6626-6636
    • Yan, P.S.1    Venkataramu, C.2    Ibrahim, A.3
  • 37
    • 0034665332 scopus 로고    scopus 로고
    • Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma
    • Eads CA, Lord RV, Kurumboor SK et al. Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma. Cancer Res 2000;60:5021-26.
    • (2000) Cancer Res , vol.60 , pp. 5021-5026
    • Eads, C.A.1    Lord, R.V.2    Kurumboor, S.K.3
  • 38
    • 33845325205 scopus 로고    scopus 로고
    • Higher methylation levels in gastric mucosae significantly correlate with higher risk of gastric cancers
    • Nakajima T, Maekita T, Oda I et al. Higher methylation levels in gastric mucosae significantly correlate with higher risk of gastric cancers. Cancer Epidemiol Biomarkers Prev 2006;15:2317-21.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 2317-2321
    • Nakajima, T.1    Maekita, T.2    Oda, I.3
  • 39
    • 84865510127 scopus 로고    scopus 로고
    • Inflammation-associated cancer development in digestive organs: Mechanisms and roles for genetic and epigenetic modulation
    • Chiba T, Marusawa H and Ushijima T. Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation. Gastroenterology 2012; 143:550-63.
    • (2012) Gastroenterology , vol.143 , pp. 550-563
    • Chiba, T.1    Marusawa, H.2    Ushijima, T.3
  • 40
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B and Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004;10:789-99.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 41
    • 84863393080 scopus 로고    scopus 로고
    • Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
    • Gerlinger M, Rowan AJ, Horswell S et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012;366:883-92.
    • (2012) N Engl J Med , vol.366 , pp. 883-892
    • Gerlinger, M.1    Rowan, A.J.2    Horswell, S.3
  • 42
    • 84874028404 scopus 로고    scopus 로고
    • Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: Potential for biomarker development
    • Baker AM, Graham TA and Wright NA. Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development. J Pathol 2013;229:502-14.
    • (2013) J Pathol , vol.229 , pp. 502-514
    • Baker, A.M.1    Graham, T.A.2    Wright, N.A.3
  • 43
    • 84885468504 scopus 로고    scopus 로고
    • Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study)
    • Williams EA, Welfare M, Spiers A et al. Systemic folate status, rectal mucosal folate concentration and dietary intake in patients at differential risk of bowel cancer (The FAB2 Study). Eur J Nutr 2013;52: 1801-10.
    • (2013) Eur J Nutr , vol.52 , pp. 1801-1810
    • Williams, E.A.1    Welfare, M.2    Spiers, A.3
  • 44
    • 84863800130 scopus 로고    scopus 로고
    • Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro
    • Charles MA, Johnson IT and Belshaw NJ. Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro. Epigenetics 2012;7:689-94.
    • (2012) Epigenetics , vol.7 , pp. 689-694
    • Charles, M.A.1    Johnson, I.T.2    Belshaw, N.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.