-
2
-
-
0032537990
-
Tamoxifen for prevention of breast cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 study
-
Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 study. J Natl Cancer Inst 1998;90:1371-88. (Pubitemid 28439961)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.18
, pp. 1371-1388
-
-
Fisher, B.1
Costantino, J.P.2
Wickerham, D.L.3
Redmond, C.K.4
Kavanah, M.5
Cronin, W.M.6
Vogel, V.7
Robidoux, A.8
Dimitrov, N.9
Atkins, J.10
Daly, M.11
Wieand, S.12
Tan-Chiu, E.13
Ford, L.14
Wolmark, N.15
-
3
-
-
0035120523
-
Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-Year results from the MORE trial
-
DOI 10.1023/A:1006478317173
-
Cauley JA, Norton L, Lippman ME, Eckert S, Krueger KA, Purdie DW, et al. Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial. Breast Cancer Res Treat 2001;65:125-34. (Pubitemid 32193616)
-
(2001)
Breast Cancer Research and Treatment
, vol.65
, Issue.2
, pp. 125-134
-
-
Cauley, J.A.1
Norton, L.2
Lippman, M.E.3
Eckert, S.4
Krueger, K.A.5
Purdie, D.W.6
Farrerons, J.7
Karasik, A.8
Mellstrom, D.9
Ng, K.W.10
Stepan, J.J.11
Powles, T.J.12
Morrow, M.13
Costa, A.14
Silfen, S.L.15
Walls, E.L.16
Schmitt, H.17
Muchmore, D.B.18
Jordan, V.C.19
-
4
-
-
79959403574
-
Exemestane for breast-cancer prevention in postmenopausal women
-
Goss PE, Ingle JN, Alés-Martínez JE, Cheung AM, Chlebowski RT, Wactawski-Wende J, et al. Exemestane for breast-cancer prevention in postmenopausal women. N Engl J Med 2011;364:2381-91.
-
(2011)
N Engl J Med
, vol.364
, pp. 2381-2391
-
-
Goss, P.E.1
Ingle, J.N.2
Alés-Martínez, J.E.3
Cheung, A.M.4
Chlebowski, R.T.5
Wactawski-Wende, J.6
-
5
-
-
80755133679
-
Progress in endocrine approaches to the treatment and prevention of breast cancer
-
Obiorah I, Jordan VC. Progress in endocrine approaches to the treatment and prevention of breast cancer. Maturitas 2011;70:315-21.
-
(2011)
Maturitas
, vol.70
, pp. 315-321
-
-
Obiorah, I.1
Jordan, V.C.2
-
6
-
-
33745613829
-
Switching to anastrozole versus continued tamoxifen treatment of early breast cancer. Updated results of the Italian tamoxifen anastrozole (ITA) trial
-
DOI 10.1093/annonc/mdl941
-
Boccardo F, Rubagotti A, Guglielmini P, Fini A, Paladini G, Mesiti M, et al. Switching to anastrozole versus continued tamoxifen treatment of early breast cancer. Updated results of the Italian tamoxifen anastrozole (ITA) trial. Ann Oncol 2006;17(Suppl 7):vii10-4. (Pubitemid 43985170)
-
(2006)
Annals of Oncology
, vol.17
, Issue.SUPPL. 7
-
-
Boccardo, F.1
Rubagotti, A.2
Guglielmini, P.3
Fini, A.4
Paladini, G.5
Mesiti, M.6
Rinaldini, M.7
Scali, S.8
Porpiglia, M.9
Benedetto, C.10
Restuccia, N.11
Buzzi, F.12
Franchi, R.13
Massidda, B.14
Distante, V.15
Amadori, D.16
Sismondi, P.17
-
7
-
-
84866122895
-
Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research
-
Singh SV, Singh K. Cancer chemoprevention with dietary isothiocyanates mature for clinical translational research. Carcinogenesis 2012; 33:1833-42.
-
(2012)
Carcinogenesis
, vol.33
, pp. 1833-1842
-
-
Singh, S.V.1
Singh, K.2
-
8
-
-
84892648502
-
Molecular targets and mechanisms of cancer prevention and treatment by withaferin A, a naturally occurring steroidal lactone
-
Vyas AR, Singh SV. Molecular targets and mechanisms of cancer prevention and treatment by withaferin A, a naturally occurring steroidal lactone. AAPS J 2014;16:1-10.
-
(2014)
AAPS J
, vol.16
, pp. 1-10
-
-
Vyas, A.R.1
Singh, S.V.2
-
9
-
-
2442587889
-
Breast Cancer Risk in Premenopausal Women Is Inversely Associated with Consumption of Broccoli, a Source of Isothiocyanates, but Is Not Modified by GST Genotype
-
Ambrosone CB, McCann SE, Freudenheim JL, Marshall JR, Zhang Y, Shields PG. Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype. J Nutr 2004;134:1134-8. (Pubitemid 38619952)
-
(2004)
Journal of Nutrition
, vol.134
, Issue.5
, pp. 1134-1138
-
-
Ambrosone, C.B.1
McCann, S.E.2
Freudenheim, J.L.3
Marshall, J.R.4
Zhang, Y.5
Shields, P.G.6
-
10
-
-
0033845752
-
Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): A review
-
Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 2000;5:334-46. (Pubitemid 30660827)
-
(2000)
Alternative Medicine Review
, vol.5
, Issue.4
, pp. 334-346
-
-
Mishra, L.-C.1
Singh, B.B.2
Dagenais, S.3
-
11
-
-
33845959087
-
Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology
-
Winters M. Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology. Altern Med Rev 2006;11:269-77. (Pubitemid 46037128)
-
(2006)
Alternative Medicine Review
, vol.11
, Issue.4
, pp. 269-277
-
-
Winters, M.1
-
12
-
-
25844455596
-
Roots of Withania somnifera inhibit forestomach and skin carcinogenesis in mice
-
DOI 10.1093/ecam/neh064
-
Padmavathi B, Rath PC, Rao AR, Singh RP. Roots of Withania somnifera inhibit forestomach and skin carcinogenesis in mice. Evid Based Complement Alternat Med 2005;2:99-105. (Pubitemid 41399520)
-
(2005)
Evidence-based Complementary and Alternative Medicine
, vol.2
, Issue.1
, pp. 99-105
-
-
Padmavathi, B.1
Rath, P.C.2
Rao, A.R.3
Singh, R.P.4
-
13
-
-
84876764334
-
Effect of an extract of Withania somnifera root on estrogen receptor-positive mammary carcinomas
-
Khazal KF, Samuel T, Hill DL, Grubbs CJ. Effect of an extract of Withania somnifera root on estrogen receptor-positive mammary carcinomas. Anticancer Res 2013;33:1519-23.
-
(2013)
Anticancer Res
, vol.33
, pp. 1519-1523
-
-
Khazal, K.F.1
Samuel, T.2
Hill, D.L.3
Grubbs, C.J.4
-
14
-
-
37749007703
-
The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats
-
Hamza A, Amin A, Daoud S. The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats. Cell Biol Toxicol 2008;24:63-73.
-
(2008)
Cell Biol Toxicol
, vol.24
, pp. 63-73
-
-
Hamza, A.1
Amin, A.2
Daoud, S.3
-
15
-
-
84879326491
-
Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients
-
Biswal BM, Sulaiman SA, Ismail HC, Zakaria H, Musa KI. Effect of Withania somnifera (Ashwagandha) on the development of chemotherapy-induced fatigue and quality of life in breast cancer patients. Integr Cancer Ther 2013;12:312-22.
-
(2013)
Integr Cancer Ther
, vol.12
, pp. 312-322
-
-
Biswal, B.M.1
Sulaiman, S.A.2
Ismail, H.C.3
Zakaria, H.4
Musa, K.I.5
-
16
-
-
68649107171
-
Steroidallactones from Withania somnifera, an ancient plant for novel medicine
-
Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J. Steroidallactones from Withania somnifera, an ancient plant for novel medicine. Molecules 2009;14:2373-93.
-
(2009)
Molecules
, vol.14
, pp. 2373-2393
-
-
Mirjalili, M.H.1
Moyano, E.2
Bonfill, M.3
Cusido, R.M.4
Palazón, J.5
-
17
-
-
84881650823
-
Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model
-
Hahm ER, Lee J, Kim SH, Sehrawat A, Arlotti JA, Shiva SS, et al. Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model. J Natl Cancer Inst 2013;105: 1111-22.
-
(2013)
J Natl Cancer Inst
, vol.105
, pp. 1111-1122
-
-
Hahm, E.R.1
Lee, J.2
Kim, S.H.3
Sehrawat, A.4
Arlotti, J.A.5
Shiva, S.S.6
-
18
-
-
54749130365
-
Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo
-
Stan SD, Hahm ER, Warin R, Singh SV. Withaferin A causes FOXO3a- and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo. Cancer Res 2008;68:7661-9.
-
(2008)
Cancer Res
, vol.68
, pp. 7661-7669
-
-
Stan, S.D.1
Hahm, E.R.2
Warin, R.3
Singh, S.V.4
-
19
-
-
80051512168
-
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species
-
Hahm ER, Moura MB, Kelley EE, Van Houten B, Shiva S, Singh SV. Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species. PLoS ONE 2011;6:e23354.
-
(2011)
PLoS ONE
, vol.6
-
-
Hahm, E.R.1
Moura, M.B.2
Kelley, E.E.3
Van Houten, B.4
Shiva, S.5
Singh, S.V.6
-
20
-
-
79960020557
-
Withaferin A suppresses estrogen receptor-a expression in human breast cancer cells
-
Hahm ER, Lee J, Huang Y, Singh SV. Withaferin A suppresses estrogen receptor-a expression in human breast cancer cells. Mol Carcinog 2011;50:614-24.
-
(2011)
Mol Carcinog
, vol.50
, pp. 614-624
-
-
Hahm, E.R.1
Lee, J.2
Huang, Y.3
Singh, S.V.4
-
21
-
-
78149239365
-
Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells
-
Lee J, Hahm ER, Singh SV. Withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells. Carcinogenesis 2010;31:1991-8.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1991-1998
-
-
Lee, J.1
Hahm, E.R.2
Singh, S.V.3
-
22
-
-
84867880152
-
Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells
-
Lee J, Sehrawat A, Singh SV. Withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells. Breast Cancer Res Treat 2012;136:45-56.
-
(2012)
Breast Cancer Res Treat
, vol.136
, pp. 45-56
-
-
Lee, J.1
Sehrawat, A.2
Singh, S.V.3
-
23
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003;100:3983-8. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
25
-
-
79952616429
-
Breast cancer stem cells and their role in resistance to endocrine therapy
-
O'Brien CS, Farnie G, Howell SJ, Clarke RB. Breast cancer stem cells and their role in resistance to endocrine therapy. Horm Cancer 2011;2:91-103.
-
(2011)
Horm Cancer
, vol.2
, pp. 91-103
-
-
O'Brien, C.S.1
Farnie, G.2
Howell, S.J.3
Clarke, R.B.4
-
26
-
-
78449305061
-
Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells
-
Jo M, Eastman BM, Webb DL, Stoletov K, Klemke R, Gonias SL. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell-like properties in breast cancer cells. Cancer Res 2010; 70:8948-58.
-
(2010)
Cancer Res
, vol.70
, pp. 8948-8958
-
-
Jo, M.1
Eastman, B.M.2
Webb, D.L.3
Stoletov, K.4
Klemke, R.5
Gonias, S.L.6
-
27
-
-
84883828864
-
Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo
-
Kim SH, Sehrawat A, Singh SV. Dietary chemopreventative benzyl isothiocyanate inhibits breast cancer stem cells in vitro and in vivo. Cancer Prev Res 2013;6:782-90.
-
(2013)
Cancer Prev Res
, vol.6
, pp. 782-790
-
-
Kim, S.H.1
Sehrawat, A.2
Singh, S.V.3
-
28
-
-
0035710746
-
-ΔΔCT method
-
DOI 10.1006/meth.2001.1262
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods 2001;25:402-8. (Pubitemid 34164012)
-
(2001)
Methods
, vol.25
, Issue.4
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
29
-
-
0037972262
-
2/M arrest and inducing apoptosis
-
DOI 10.1093/carcin/bgg023
-
Xiao D, Srivastava SK, Lew KL, Zeng Y, Hershberger P, Johnson CS, et al. Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits proliferation of human prostate cancer cells by causing G2/M arrest and inducing apoptosis. Carcinogenesis 2003;24:891-7. (Pubitemid 36748905)
-
(2003)
Carcinogenesis
, vol.24
, Issue.5
, pp. 891-897
-
-
Xiao, D.1
Srivastava, S.K.2
Lew, K.L.3
Zeng, Y.4
Hershberger, P.5
Johnson, C.S.6
Trump, D.L.7
Singh, S.V.8
-
30
-
-
79953838313
-
Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer
-
Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, Nelson JB, et al. Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer. J Natl Cancer Inst 2011;103:571-84.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 571-584
-
-
Powolny, A.A.1
Bommareddy, A.2
Hahm, E.R.3
Normolle, D.P.4
Beumer, J.H.5
Nelson, J.B.6
-
31
-
-
80053309063
-
Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
-
Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, et al. Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. Int J Cancer 2011;129:2744-55.
-
(2011)
Int J Cancer
, vol.129
, pp. 2744-2755
-
-
Thaiparambil, J.T.1
Bender, L.2
Ganesh, T.3
Kline, E.4
Patel, P.5
Liu, Y.6
-
32
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S, Dontu G, Mantle ID, Patel S, Ahn NS, Jackson KW, et al. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res 2006;66:6063-71.
-
(2006)
Cancer Res
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.S.5
Jackson, K.W.6
-
33
-
-
76549084826
-
Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor
-
Harrison H, Farnie G, Howell SJ, Rock RE, Stylianou S, Brennan KR, et al. Regulation of breast cancer stem cell activity by signaling through the Notch4 receptor. Cancer Res 2010;70:709-18.
-
(2010)
Cancer Res
, vol.70
, pp. 709-718
-
-
Harrison, H.1
Farnie, G.2
Howell, S.J.3
Rock, R.E.4
Stylianou, S.5
Brennan, K.R.6
-
34
-
-
79955608022
-
Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
-
Yu F, Li J, Chen H, Fu J, Ray S, Huang S, et al. Kruppel-like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion. Oncogene 2011;30:2161-72.
-
(2011)
Oncogene
, vol.30
, pp. 2161-2172
-
-
Yu, F.1
Li, J.2
Chen, H.3
Fu, J.4
Ray, S.5
Huang, S.6
-
36
-
-
74949129868
-
Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
-
Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, Esterni B, et al. Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 2010;16:45-55.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 45-55
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Iovino, F.3
Tarpin, C.4
Diebel, M.5
Esterni, B.6
-
37
-
-
84860175405
-
Notch-1 and Notch-4 biomarker expression in triple-negative breast cancer
-
Speiser J, Foreman K, Drinka E, Godellas C, Perez C, Salhadar A, et al. Notch-1 and Notch-4 biomarker expression in triple-negative breast cancer. Int J Surg Pathol 2012;20:139-45.
-
(2012)
Int J Surg Pathol
, vol.20
, pp. 139-145
-
-
Speiser, J.1
Foreman, K.2
Drinka, E.3
Godellas, C.4
Perez, C.5
Salhadar, A.6
-
38
-
-
30144442965
-
KLF4, p21 and context-dependent opposing forces in cancer
-
DOI 10.1038/nrc1780
-
Rowland BD, Peeper DS. KLF4, p21, and context-dependent opposing forces in cancer. Nat Rev Cancer 2006;6:11-23. (Pubitemid 43053649)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.1
, pp. 11-23
-
-
Rowland, B.D.1
Peeper, D.S.2
-
39
-
-
0033693134
-
Increase of GKLF messenger RNA and protein expression during progression of breast cancer
-
Foster KW, Frost AR, McKie-Bell P, Lin CY, Engler JA, Grizzle WE, et al. Increase of GKLF messenger RNA and protein expression during progression of breast cancer. Cancer Res 2000;60:6488-95.
-
(2000)
Cancer Res
, vol.60
, pp. 6488-6495
-
-
Foster, K.W.1
Frost, A.R.2
McKie-Bell, P.3
Lin, C.Y.4
Engler, J.A.5
Grizzle, W.E.6
-
40
-
-
11144358328
-
Nuclear Localization of KLF4 Is Associated with An Aggressive Phenotype in Early-Stage Breast Cancer
-
DOI 10.1158/1078-0432.CCR-03-0484
-
Pandya AY, Talley LI, Frost AR, Fitzgerald TJ, Trivedi V, Chakravarthy M, et al. Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer. Clin Cancer Res 2004;10: 2709-19. (Pubitemid 38509146)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.8
, pp. 2709-2719
-
-
Pandya, A.Y.1
Talley, L.I.2
Frost, A.R.3
Fitzgerald, T.J.4
Trivedi, V.5
Chakravarthy, M.6
Chhieng, D.C.7
Grizzle, W.E.8
Engler, J.A.9
Krontiras, H.10
Bland, K.I.11
LoBuglio, A.F.12
Lobo-Ruppert, S.M.13
Ruppert, J.M.14
-
41
-
-
84874653875
-
Molecularly targeted therapies for metastatic triple-negative breast cancer
-
Bayraktar S, Glück S. Molecularly targeted therapies for metastatic triple-negative breast cancer. Breast Cancer Res Treat 2013;138: 21-35.
-
(2013)
Breast Cancer Res Treat
, vol.138
, pp. 21-35
-
-
Bayraktar, S.1
Glück, S.2
-
42
-
-
84892666303
-
Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with downregulation and covalent binding at cysteine-303 of β-tubulin
-
Antony ML, Lee J, Hahm ER, Kim SH, Marcus AI, Kumari V, et al. Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with downregulation and covalent binding at cysteine-303 of β-tubulin. J Biol Chem 2014;289:1852-65.
-
(2014)
J Biol Chem
, vol.289
, pp. 1852-1865
-
-
Antony, M.L.1
Lee, J.2
Hahm, E.R.3
Kim, S.H.4
Marcus, A.I.5
Kumari, V.6
-
43
-
-
79952012742
-
Molecular targets of phytochemicals for cancer prevention
-
Lee KW, Bode AM, Dong Z. Molecular targets of phytochemicals for cancer prevention. Nat Rev Cancer 2011;11:211-8.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 211-218
-
-
Lee, K.W.1
Bode, A.M.2
Dong, Z.3
|