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Volumn 592, Issue 14, 2014, Pages 3063-3073

Exercise training modulates functional sympatholysis and α-adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA ADRENERGIC RECEPTOR; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y2 RECEPTOR; TYRAMINE; ADRENERGIC RECEPTOR AFFECTING AGENT; ADRENERGIC RECEPTOR STIMULATING AGENT; PURINERGIC P2X1 RECEPTOR; VASODILATOR AGENT;

EID: 84904348536     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2014.273722     Document Type: Article
Times cited : (62)

References (47)
  • 1
    • 33847448896 scopus 로고
    • Observations in man upon a blood pressure raising reflex arising from the voluntary muscles
    • Alam M & Smirk FH (1937). Observations in man upon a blood pressure raising reflex arising from the voluntary muscles. J Physiol 89, 372-383.
    • (1937) J Physiol , vol.89 , pp. 372-383
    • Alam, M.1    Smirk, F.H.2
  • 2
    • 0013866977 scopus 로고
    • Reaction in man of resistance and capacity vessels in forearm and hand to leg exercise
    • Bevegard BS & Shepherd JT (1966). Reaction in man of resistance and capacity vessels in forearm and hand to leg exercise. J Appl Physiol 21, 123-132.
    • (1966) J Appl Physiol , vol.21 , pp. 123-132
    • Bevegard, B.S.1    Shepherd, J.T.2
  • 3
    • 84891133400 scopus 로고    scopus 로고
    • Purinergic signaling and blood vessels in health and disease
    • Burnstock G & Ralevic V (2014). Purinergic signaling and blood vessels in health and disease. Pharmacol Rev 66, 102-192.
    • (2014) Pharmacol Rev , vol.66 , pp. 102-192
    • Burnstock, G.1    Ralevic, V.2
  • 4
    • 0028031462 scopus 로고
    • Arm muscle sympathetic nerve activity during preparation for and initiation of leg-cycling exercise in humans
    • Callister R, Ng AV & Seals DR (1994). Arm muscle sympathetic nerve activity during preparation for and initiation of leg-cycling exercise in humans. J Appl Physiol 77, 1403-1410.
    • (1994) J Appl Physiol , vol.77 , pp. 1403-1410
    • Callister, R.1    Ng, A.V.2    Seals, D.R.3
  • 5
    • 26844532136 scopus 로고    scopus 로고
    • Balance between cardiac output and sympathetic nerve activity in resting humans: role in arterial pressure regulation
    • Charkoudian N, Joyner MJ, Johnson CP, Eisenach JH, Dietz NM & Wallin BG (2005). Balance between cardiac output and sympathetic nerve activity in resting humans: role in arterial pressure regulation. J Physiol 568, 315-321.
    • (2005) J Physiol , vol.568 , pp. 315-321
    • Charkoudian, N.1    Joyner, M.J.2    Johnson, C.P.3    Eisenach, J.H.4    Dietz, N.M.5    Wallin, B.G.6
  • 6
    • 0036554973 scopus 로고    scopus 로고
    • Nitric oxide-dependent modulation of sympathetic neural control of oxygenation in exercising human skeletal muscle
    • Chavoshan B, Sander M, Sybert TE, Hansen J, Victor RG & Thomas GD (2002). Nitric oxide-dependent modulation of sympathetic neural control of oxygenation in exercising human skeletal muscle. J Physiol 540, 377-386.
    • (2002) J Physiol , vol.540 , pp. 377-386
    • Chavoshan, B.1    Sander, M.2    Sybert, T.E.3    Hansen, J.4    Victor, R.G.5    Thomas, G.D.6
  • 7
    • 84868135875 scopus 로고    scopus 로고
    • ATP-mediated vasodilatation occurs via activation of inwardly-rectifying potassium channels in humans
    • Crecelius AR, Kirby BS, Luckasen GJ, Larson DG & Dinenno FA (2012). ATP-mediated vasodilatation occurs via activation of inwardly-rectifying potassium channels in humans. J Physiol 590, 5349-5359.
    • (2012) J Physiol , vol.590 , pp. 5349-5359
    • Crecelius, A.R.1    Kirby, B.S.2    Luckasen, G.J.3    Larson, D.G.4    Dinenno, F.A.5
  • 9
    • 33846946826 scopus 로고    scopus 로고
    • Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles
    • Donato AJ, Lesniewski LA & Delp MD (2007). Ageing and exercise training alter adrenergic vasomotor responses of rat skeletal muscle arterioles. J Physiol 579, 115-125.
    • (2007) J Physiol , vol.579 , pp. 115-125
    • Donato, A.J.1    Lesniewski, L.A.2    Delp, M.D.3
  • 10
    • 0023473458 scopus 로고
    • Mechanism of increased alpha adrenergic vasoconstriction in human essential hypertension
    • Egan B, Panis R, Hinderliter A, Schork N & Julius S (1987). Mechanism of increased alpha adrenergic vasoconstriction in human essential hypertension. J Clin Invest 80, 812-817.
    • (1987) J Clin Invest , vol.80 , pp. 812-817
    • Egan, B.1    Panis, R.2    Hinderliter, A.3    Schork, N.4    Julius, S.5
  • 12
    • 84863754429 scopus 로고    scopus 로고
    • Regulation of blood flow distribution in skeletal muscle: role of erythrocyte-released ATP
    • Ellsworth ML & Sprague RS (2012). Regulation of blood flow distribution in skeletal muscle: role of erythrocyte-released ATP. J Physiol 590, 4985-4991.
    • (2012) J Physiol , vol.590 , pp. 4985-4991
    • Ellsworth, M.L.1    Sprague, R.S.2
  • 13
    • 84862907947 scopus 로고    scopus 로고
    • Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate tolerant rats and humans
    • Fadel PJ, Farias M, Gallagher KM, Wang Z & Thomas GD (2012). Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate tolerant rats and humans. J Physiol 590, 395-407.
    • (2012) J Physiol , vol.590 , pp. 395-407
    • Fadel, P.J.1    Farias, M.2    Gallagher, K.M.3    Wang, Z.4    Thomas, G.D.5
  • 14
    • 11444268982 scopus 로고    scopus 로고
    • Augmented sympathetic vasoconstriction in exercising forearms of postmenopausal women is reversed by oestrogen therapy
    • Fadel PJ, Wang Z, Watanabe H, Arbique D, Vongpatanasin W & Thomas GD (2004). Augmented sympathetic vasoconstriction in exercising forearms of postmenopausal women is reversed by oestrogen therapy. J Physiol 561, 893-901.
    • (2004) J Physiol , vol.561 , pp. 893-901
    • Fadel, P.J.1    Wang, Z.2    Watanabe, H.3    Arbique, D.4    Vongpatanasin, W.5    Thomas, G.D.6
  • 15
    • 84867477826 scopus 로고    scopus 로고
    • ATP as a mediator of erythrocyte-dependent regulation of skeletal muscle blood flow and oxygen delivery in humans
    • González-Alonso J (2012). ATP as a mediator of erythrocyte-dependent regulation of skeletal muscle blood flow and oxygen delivery in humans. J Physiol 590, 5001-5013.
    • (2012) J Physiol , vol.590 , pp. 5001-5013
    • González-Alonso, J.1
  • 16
    • 0029778780 scopus 로고    scopus 로고
    • Differential sympathetic neural control of oxygenation in resting and exercising human skeletal muscle
    • Hansen J, Thomas GD, Harris SA, Parsons WJ & Victor RG (1996). Differential sympathetic neural control of oxygenation in resting and exercising human skeletal muscle. J Clin Invest 98, 584-596.
    • (1996) J Clin Invest , vol.98 , pp. 584-596
    • Hansen, J.1    Thomas, G.D.2    Harris, S.A.3    Parsons, W.J.4    Victor, R.G.5
  • 17
    • 0028050848 scopus 로고
    • Muscle metaboreflex triggers parallel sympathetic activation in exercising and resting human skeletal muscle
    • Hansen J, Thomas GD, Jacobsen TN & Victor RG (1994). Muscle metaboreflex triggers parallel sympathetic activation in exercising and resting human skeletal muscle. Am J Physiol 266, H2508-H2514.
    • (1994) Am J Physiol , vol.266
    • Hansen, J.1    Thomas, G.D.2    Jacobsen, T.N.3    Victor, R.G.4
  • 18
    • 84871077211 scopus 로고    scopus 로고
    • Vasodilator interactions in skeletal muscle blood flow regulation
    • Hellsten Y, Nyberg M, Jensen LG & Mortensen SP (2012a). Vasodilator interactions in skeletal muscle blood flow regulation. J Physiol 590, 6297-6305.
    • (2012) J Physiol , vol.590 , pp. 6297-6305
    • Hellsten, Y.1    Nyberg, M.2    Jensen, L.G.3    Mortensen, S.P.4
  • 19
    • 84866566075 scopus 로고    scopus 로고
    • Impaired formation of vasodilators in peripheral tissue in essential hypertension is normalized by exercise training: role of adenosine and prostacyclin
    • Hellsten Y, Jensen L, Thaning P, Nyberg M & Mortensen S (2012b). Impaired formation of vasodilators in peripheral tissue in essential hypertension is normalized by exercise training: role of adenosine and prostacyclin. J Hypertens 30, 2007-2014.
    • (2012) J Hypertens , vol.30 , pp. 2007-2014
    • Hellsten, Y.1    Jensen, L.2    Thaning, P.3    Nyberg, M.4    Mortensen, S.5
  • 20
    • 0016635565 scopus 로고
    • Cardiac acceleration in man elicited by a muscle-heart reflex
    • Hollander AP & Bouman LN (1975). Cardiac acceleration in man elicited by a muscle-heart reflex. J Appl Physiol 38, 272-278.
    • (1975) J Appl Physiol , vol.38 , pp. 272-278
    • Hollander, A.P.1    Bouman, L.N.2
  • 21
    • 77953810427 scopus 로고    scopus 로고
    • Sympathetic nervous system and blood pressure in humans: individualized patterns of regulation and their implications
    • Joyner MJ, Charkoudian N & Wallin BG (2010). Sympathetic nervous system and blood pressure in humans: individualized patterns of regulation and their implications. Hypertension 56, 10-16.
    • (2010) Hypertension , vol.56 , pp. 10-16
    • Joyner, M.J.1    Charkoudian, N.2    Wallin, B.G.3
  • 23
    • 0020652321 scopus 로고
    • The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways
    • Mitchell JH, Kaufman MP & Iwamoto GA (1983). The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways. Annu Rev Physiol 45, 229-242.
    • (1983) Annu Rev Physiol , vol.45 , pp. 229-242
    • Mitchell, J.H.1    Kaufman, M.P.2    Iwamoto, G.A.3
  • 24
    • 84868105599 scopus 로고    scopus 로고
    • Lifelong physical activity preserves functional sympatholysis and purinergic signalling in the ageing human leg
    • Mortensen SP, Nyberg M, Winding K & Saltin B (2012a). Lifelong physical activity preserves functional sympatholysis and purinergic signalling in the ageing human leg. J Physiol 590, 6227-6236.
    • (2012) J Physiol , vol.590 , pp. 6227-6236
    • Mortensen, S.P.1    Nyberg, M.2    Winding, K.3    Saltin, B.4
  • 26
    • 84861173125 scopus 로고    scopus 로고
    • Two weeks of muscle immobilization impairs functional sympatholysis, but increases exercise hyperemia and the vasodilatory responsiveness to infused ATP
    • Mortensen SP, Mørkeberg J, Thaning P, Hellsten Y & Saltin B (2012b). Two weeks of muscle immobilization impairs functional sympatholysis, but increases exercise hyperemia and the vasodilatory responsiveness to infused ATP. Am J Physiol Heart Circ Physiol 302, H2074-H2082.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302
    • Mortensen, S.P.1    Mørkeberg, J.2    Thaning, P.3    Hellsten, Y.4    Saltin, B.5
  • 27
    • 84873418051 scopus 로고    scopus 로고
    • Physical activity opposes the age-related increase in skeletal muscle and plasma endothelin-1 levels and normalizes plasma endothelin-1 levels in individuals with essential hypertension
    • Nyberg M, Mortensen SP & Hellsten Y (2013). Physical activity opposes the age-related increase in skeletal muscle and plasma endothelin-1 levels and normalizes plasma endothelin-1 levels in individuals with essential hypertension. Acta Physiol (Oxf) 207, 524-535.
    • (2013) Acta Physiol (Oxf) , vol.207 , pp. 524-535
    • Nyberg, M.1    Mortensen, S.P.2    Hellsten, Y.3
  • 28
    • 84868104223 scopus 로고    scopus 로고
    • Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans
    • Nyberg M, Blackwell JR, Damsgaard R, Jones AM, Hellsten Y & Mortensen SP (2012a). Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans. J Physiol 590, 5361-5370.
    • (2012) J Physiol , vol.590 , pp. 5361-5370
    • Nyberg, M.1    Blackwell, J.R.2    Damsgaard, R.3    Jones, A.M.4    Hellsten, Y.5    Mortensen, S.P.6
  • 29
    • 84858175927 scopus 로고    scopus 로고
    • Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training
    • Nyberg M, Jensen LG, Thaning P, Hellsten Y & Mortensen SP (2012b). Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training. J Physiol 590, 1481-1494.
    • (2012) J Physiol , vol.590 , pp. 1481-1494
    • Nyberg, M.1    Jensen, L.G.2    Thaning, P.3    Hellsten, Y.4    Mortensen, S.P.5
  • 30
    • 84860609944 scopus 로고    scopus 로고
    • The human sympathetic nervous system: its relevance in hypertension and heart failure
    • Parati G & Esler M (2012). The human sympathetic nervous system: its relevance in hypertension and heart failure. Eur Heart J 33, 1058-1066.
    • (2012) Eur Heart J , vol.33 , pp. 1058-1066
    • Parati, G.1    Esler, M.2
  • 31
    • 0036082346 scopus 로고    scopus 로고
    • Heterogeneous responses of human limbs to infused adrenergic agonists: a gravitational effect?
    • Pawelczyk JA & Levine BD (2002). Heterogeneous responses of human limbs to infused adrenergic agonists: a gravitational effect? J Appl Physiol 92, 2105-2113.
    • (2002) J Appl Physiol , vol.92 , pp. 2105-2113
    • Pawelczyk, J.A.1    Levine, B.D.2
  • 32
    • 0022590909 scopus 로고
    • Crucial role of endothelium in the vasodilator response to increased flow in vivo
    • Pohl U, Holtz J, Busse R & Bassenge E (1986). Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension 8, 37-44.
    • (1986) Hypertension , vol.8 , pp. 37-44
    • Pohl, U.1    Holtz, J.2    Busse, R.3    Bassenge, E.4
  • 34
    • 0028963287 scopus 로고
    • Sympathetic nerve activity to nonactive muscle of the exercising and nonexercising limb
    • Ray CA & Mark AL (1995). Sympathetic nerve activity to nonactive muscle of the exercising and nonexercising limb. Med Sci Sports Exerc 27, 183-187.
    • (1995) Med Sci Sports Exerc , vol.27 , pp. 183-187
    • Ray, C.A.1    Mark, A.L.2
  • 35
    • 0001583365 scopus 로고
    • Functional sympatholysis during muscular activity. Observations on influence of carotid sinus on oxygen uptake
    • Remensnyder J, Mitchell JH & Sarnoff SJ (1962). Functional sympatholysis during muscular activity. Observations on influence of carotid sinus on oxygen uptake. Circ Res 11, 370-380.
    • (1962) Circ Res , vol.11 , pp. 370-380
    • Remensnyder, J.1    Mitchell, J.H.2    Sarnoff, S.J.3
  • 36
    • 4043183981 scopus 로고    scopus 로고
    • Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscle
    • Rosenmeier JB, Hansen J & González-Alonso J (2004). Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscle. J Physiol 558, 351-365.
    • (2004) J Physiol , vol.558 , pp. 351-365
    • Rosenmeier, J.B.1    Hansen, J.2    González-Alonso, J.3
  • 37
    • 0345276708 scopus 로고    scopus 로고
    • Exogenous NO administration and α-adrenergic vasoconstriction in human limbs
    • Rosenmeier JB, Fritzlar SJ, Dinenno FA & Joyner MJ (2003). Exogenous NO administration and α-adrenergic vasoconstriction in human limbs. J Appl Physiol 95, 2370-2374.
    • (2003) J Appl Physiol , vol.95 , pp. 2370-2374
    • Rosenmeier, J.B.1    Fritzlar, S.J.2    Dinenno, F.A.3    Joyner, M.J.4
  • 38
    • 0003627553 scopus 로고
    • ed. Rowell LB, Oxford University Press, New York.
    • Rowell LB (1993). Human cardiovascular control. ed. Rowell LB, p. 500. Oxford University Press, New York.
    • (1993) Human cardiovascular control , pp. 500
    • Rowell, L.B.1
  • 39
    • 0027257548 scopus 로고
    • Muscle sympathetic nerve responses to graded leg cycling
    • Saito M, Tsukanaka A, Yanagihara D & Mano T (1993). Muscle sympathetic nerve responses to graded leg cycling. J Appl Physiol 75, 663-667.
    • (1993) J Appl Physiol , vol.75 , pp. 663-667
    • Saito, M.1    Tsukanaka, A.2    Yanagihara, D.3    Mano, T.4
  • 40
    • 84871055884 scopus 로고    scopus 로고
    • Inefficient functional sympatholysis is an overlooked cause of malperfusion in contracting skeletal muscle
    • Saltin B & Mortensen SP (2012). Inefficient functional sympatholysis is an overlooked cause of malperfusion in contracting skeletal muscle. J Physiol 590, 6269-6275.
    • (2012) J Physiol , vol.590 , pp. 6269-6275
    • Saltin, B.1    Mortensen, S.P.2
  • 41
    • 0025932378 scopus 로고
    • Regulation of muscle sympathetic nerve activity during exercise in humans
    • Seals DR & Victor RG (1991). Regulation of muscle sympathetic nerve activity during exercise in humans. Exerc Sport Sci Rev 19, 313-349.
    • (1991) Exerc Sport Sci Rev , vol.19 , pp. 313-349
    • Seals, D.R.1    Victor, R.G.2
  • 42
    • 0032898549 scopus 로고    scopus 로고
    • Cardiovascular control during concomitant dynamic leg exercise and static arm exercise in humans
    • Strange S (1999). Cardiovascular control during concomitant dynamic leg exercise and static arm exercise in humans. J Physiol 514, 283-291.
    • (1999) J Physiol , vol.514 , pp. 283-291
    • Strange, S.1
  • 44
    • 0027972194 scopus 로고
    • Inhibition of alpha 2-adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat hindlimb muscle
    • Thomas GD, Hansen J & Victor RG (1994). Inhibition of alpha 2-adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat hindlimb muscle. Am J Physiol 266, H920-H929.
    • (1994) Am J Physiol , vol.266
    • Thomas, G.D.1    Hansen, J.2    Victor, R.G.3
  • 45
    • 0036623916 scopus 로고    scopus 로고
    • Is sympathetic neural vasoconstriction blunted in the vascular bed of exercising human muscle?
    • Tschakovsky ME, Sujirattanawimol K, Ruble SB, Valic Z & Joyner MJ (2002). Is sympathetic neural vasoconstriction blunted in the vascular bed of exercising human muscle? J Physiol 541, 623-635.
    • (2002) J Physiol , vol.541 , pp. 623-635
    • Tschakovsky, M.E.1    Sujirattanawimol, K.2    Ruble, S.B.3    Valic, Z.4    Joyner, M.J.5
  • 47
    • 0037590102 scopus 로고    scopus 로고
    • Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions
    • Yegutkin GG, Samburski SS & Jalkanen S (2003). Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions. FASEB J 17, 1328-1330.
    • (2003) FASEB J , vol.17 , pp. 1328-1330
    • Yegutkin, G.G.1    Samburski, S.S.2    Jalkanen, S.3


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