메뉴 건너뛰기




Volumn 590, Issue 21, 2012, Pages 5361-5370

Lifelong physical activity prevents an age-related reduction in arterial and skeletal muscle nitric oxide bioavailability in humans

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

EID: 84868104223     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.239053     Document Type: Article
Times cited : (100)

References (40)
  • 1
    • 0022270890 scopus 로고
    • Maximal perfusion of skeletal muscle in man
    • Andersen P & Saltin B (1985). Maximal perfusion of skeletal muscle in man. J Physiol 366, 233-249.
    • (1985) J Physiol , vol.366 , pp. 233-249
    • Andersen, P.1    Saltin, B.2
  • 5
    • 12444339796 scopus 로고    scopus 로고
    • Pharmacokinetics of intravenous N-acetylcysteine in men at rest and during exercise
    • Brown M, Bjorksten A, Medved I & McKenna M (2004). Pharmacokinetics of intravenous N-acetylcysteine in men at rest and during exercise. Eur J Clin Pharmacol 60, 717-723.
    • (2004) Eur J Clin Pharmacol , vol.60 , pp. 717-723
    • Brown, M.1    Bjorksten, A.2    Medved, I.3    McKenna, M.4
  • 6
    • 0032880516 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibition reduces leg glucose uptake but not blood flow during dynamic exercise in humans
    • Bradley SJ, Kingwell BA & McConell GK (1999). Nitric oxide synthase inhibition reduces leg glucose uptake but not blood flow during dynamic exercise in humans. Diabetes 48, 1815-1821.
    • (1999) Diabetes , vol.48 , pp. 1815-1821
    • Bradley, S.J.1    Kingwell, B.A.2    McConell, G.K.3
  • 7
    • 3042610250 scopus 로고    scopus 로고
    • Vasodilatory mechanisms in contracting skeletal muscle
    • Clifford PS & Hellsten Y (2004). Vasodilatory mechanisms in contracting skeletal muscle. J Appl Physiol 97, 393-403.
    • (2004) J Appl Physiol , vol.97 , pp. 393-403
    • Clifford, P.S.1    Hellsten, Y.2
  • 8
    • 60449094156 scopus 로고    scopus 로고
    • The effects of ageing on capillary hemodynamics in contracting rat spinotrapezius muscle
    • Copp SW, Ferreira LF, Herspring KF, Musch TI & Poole DC (2009). The effects of ageing on capillary hemodynamics in contracting rat spinotrapezius muscle. Mircovasc Res 77, 113-119.
    • (2009) Mircovasc Res , vol.77 , pp. 113-119
    • Copp, S.W.1    Ferreira, L.F.2    Herspring, K.F.3    Musch, T.I.4    Poole, D.C.5
  • 9
    • 78249257619 scopus 로고    scopus 로고
    • Nitric oxide, but not vasodilating prostaglandins, contributes to the improvement of exercise hyperaemia via ascorbic acid in healthy older adults
    • Crecelius AR, Kirby BS, Voyles WF & Dinenno FA (2010). Nitric oxide, but not vasodilating prostaglandins, contributes to the improvement of exercise hyperaemia via ascorbic acid in healthy older adults. Am J Physiol Heart Circ Physiol 299, 1633-1641.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. 1633-1641
    • Crecelius, A.R.1    Kirby, B.S.2    Voyles, W.F.3    Dinenno, F.A.4
  • 11
    • 67650354412 scopus 로고    scopus 로고
    • Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase
    • Durrant JR, Seals DR, Connell ML, Russell MJ, Lawson BR, Folian BJ, Donato AJ & Lesniewski LA (2009). Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase. J Physiol 587, 3271-3285.
    • (2009) J Physiol , vol.587 , pp. 3271-3285
    • Durrant, J.R.1    Seals, D.R.2    Connell, M.L.3    Russell, M.J.4    Lawson, B.R.5    Folian, B.J.6    Donato, A.J.7    Lesniewski, L.A.8
  • 12
    • 1942438660 scopus 로고    scopus 로고
    • Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing
    • Eskurza I, Monahan KD, Robinson JA & Seals DR (2004). Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing. J Physiol 556, 315-324.
    • (2004) J Physiol , vol.556 , pp. 315-324
    • Eskurza, I.1    Monahan, K.D.2    Robinson, J.A.3    Seals, D.R.4
  • 13
    • 0033798760 scopus 로고    scopus 로고
    • G-monomethyl-L-arginine administration in humans: Effects of interstitial adenosine, prostacyclin and potassium concentrations in resting and contracting skeletal muscle
    • G-monomethyl-L-arginine administration in humans: Effects of interstitial adenosine, prostacyclin and potassium concentrations in resting and contracting skeletal muscle. J Vasc Res 37, 297-302.
    • (2000) J Vasc Res , vol.37 , pp. 297-302
    • Frandsen, U.1    Bangsbo, J.2    Langberg, H.3    Saltin, B.4    Hellsten, Y.5
  • 14
    • 25144467648 scopus 로고    scopus 로고
    • Functional hyperaemia is reduced in skeletal muscle of aged rats
    • Hammer LW & Boegehold MA (2005). Functional hyperaemia is reduced in skeletal muscle of aged rats. Microcirculation 12, 517-526.
    • (2005) Microcirculation , vol.12 , pp. 517-526
    • Hammer, L.W.1    Boegehold, M.A.2
  • 15
    • 0035097953 scopus 로고    scopus 로고
    • Superoxide excess in hypertension and ageing: a common cause of endothelial dysfunction
    • Hamilton CA, Brosnan MJ, McIntyre M, Graham D & Dominiczak AF (2001). Superoxide excess in hypertension and ageing: a common cause of endothelial dysfunction. Hypertension 37, 529-534.
    • (2001) Hypertension , vol.37 , pp. 529-534
    • Hamilton, C.A.1    Brosnan, M.J.2    McIntyre, M.3    Graham, D.4    Dominiczak, A.F.5
  • 16
    • 0028289885 scopus 로고
    • An improved method to calculate adipose tissue interstitial substrate recovery for microdialysis studies
    • Jansson PA, Veneman T, Nurjhan N & Gerich J (1994). An improved method to calculate adipose tissue interstitial substrate recovery for microdialysis studies. Life Sci 54, 1621-1624.
    • (1994) Life Sci , vol.54 , pp. 1621-1624
    • Jansson, P.A.1    Veneman, T.2    Nurjhan, N.3    Gerich, J.4
  • 18
    • 70349857838 scopus 로고    scopus 로고
    • The catacholamines strike back - what NO does not
    • Joyner MJ & Casey DP (2009). The catacholamines strike back - what NO does not. Circ J 73, 1783-1792.
    • (2009) Circ J , vol.73 , pp. 1783-1792
    • Joyner, M.J.1    Casey, D.P.2
  • 19
    • 65449164223 scopus 로고    scopus 로고
    • Endothelium-dependent vasodilatation and exercise hyperaemia in ageing humans: impact of acute ascorbic acid administration
    • Kirby BS, Voyles WF, Simpson CB, Carlson RE, Schrage WG & Dinenno FA (2009). Endothelium-dependent vasodilatation and exercise hyperaemia in ageing humans: impact of acute ascorbic acid administration. J Physiol 587, 1989-2003.
    • (2009) J Physiol , vol.587 , pp. 1989-2003
    • Kirby, B.S.1    Voyles, W.F.2    Simpson, C.B.3    Carlson, R.E.4    Schrage, W.G.5    Dinenno, F.A.6
  • 21
    • 84861226595 scopus 로고    scopus 로고
    • The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle
    • Larsen S, Hey-Mogensen M, Rabol R, Stride N, Helge JW & Dela F (2012). The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle. Acta Physiol 205, 423-432.
    • (2012) Acta Physiol , vol.205 , pp. 423-432
    • Larsen, S.1    Hey-Mogensen, M.2    Rabol, R.3    Stride, N.4    Helge, J.W.5    Dela, F.6
  • 22
    • 0035940415 scopus 로고    scopus 로고
    • Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action
    • Lauer T, Preik M, Rassaf T, Strauer BE, Deussen A, Feelisch M & Kelm M (2001). Plasma nitrite rather than nitrate reflects regional endothelial nitric oxide synthase activity but lacks intrinsic vasodilator action. Proc Natl Acad Sci U S A 98, 12814-12819.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 12814-12819
    • Lauer, T.1    Preik, M.2    Rassaf, T.3    Strauer, B.E.4    Deussen, A.5    Feelisch, M.6    Kelm, M.7
  • 24
    • 0037377633 scopus 로고    scopus 로고
    • N-Acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans
    • Medved I, Brown MJ, Bjorksten AR, Leppik JA, Sostaric S & McKenna MJ (2003). N-Acetylcysteine infusion alters blood redox status but not time to fatigue during intense exercise in humans. J Appl Physiol 94, 1572-1582.
    • (2003) J Appl Physiol , vol.94 , pp. 1572-1582
    • Medved, I.1    Brown, M.J.2    Bjorksten, A.R.3    Leppik, J.A.4    Sostaric, S.5    McKenna, M.J.6
  • 25
    • 84868105599 scopus 로고    scopus 로고
    • Lifelong physical activity preserves functional sympatholysis and purinergic signaling in the human leg
    • (in press).
    • Mortensen SP, Nyberg M, Winding K & Saltin B (2012). Lifelong physical activity preserves functional sympatholysis and purinergic signaling in the human leg. J Physiol (in press).
    • (2012) J Physiol
    • Mortensen, S.P.1    Nyberg, M.2    Winding, K.3    Saltin, B.4
  • 28
    • 84858175927 scopus 로고    scopus 로고
    • Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training
    • Nyberg M, Jensen LG, Thaning P, Hellsten Y & Mortensen SP (2012). Role of nitric oxide and prostanoids in the regulation of leg blood flow and blood pressure in humans with essential hypertension: effect of high-intensity aerobic training. J Physiol 590, 1481-1494.
    • (2012) J Physiol , vol.590 , pp. 1481-1494
    • Nyberg, M.1    Jensen, L.G.2    Thaning, P.3    Hellsten, Y.4    Mortensen, S.P.5
  • 30
    • 33847699009 scopus 로고    scopus 로고
    • Oxygen exchange in muscle of young and old rats: muscle-vascular-pulmonary coupling
    • Poole DC & Ferreira LF (2007). Oxygen exchange in muscle of young and old rats: muscle-vascular-pulmonary coupling. Exp Physiol 92, 341-346.
    • (2007) Exp Physiol , vol.92 , pp. 341-346
    • Poole, D.C.1    Ferreira, L.F.2
  • 32
    • 0042707789 scopus 로고    scopus 로고
    • Experimental evidence against the mitochondrial theory of ageing. A study of isolated human skeletal muscle mitochondria
    • Rasmussen UF, Krustrup P, Kjaer M & Rasmussen HN (2003). Experimental evidence against the mitochondrial theory of ageing. A study of isolated human skeletal muscle mitochondria. Exp Gerontol 38, 877-886.
    • (2003) Exp Gerontol , vol.38 , pp. 877-886
    • Rasmussen, U.F.1    Krustrup, P.2    Kjaer, M.3    Rasmussen, H.N.4
  • 33
    • 0344436089 scopus 로고    scopus 로고
    • Nitric oxide in the regulation of vasomotor tone in human skeletal muscle
    • Rådegran G & Saltin B (1999). Nitric oxide in the regulation of vasomotor tone in human skeletal muscle. Am J Physiol Heart Circ Physiol 276, H1951-1960.
    • (1999) Am J Physiol Heart Circ Physiol , vol.276
    • Rådegran, G.1    Saltin, B.2
  • 34
    • 0025751618 scopus 로고
    • The internal reference technique in microdialysis: a practical approach to monitoring dialysis efficiency and calculating tissue concentration from dialysate samples
    • Scheller D & Kolb J (1991). The internal reference technique in microdialysis: a practical approach to monitoring dialysis efficiency and calculating tissue concentration from dialysate samples. J Neurosci Methods 40, 31-38.
    • (1991) J Neurosci Methods , vol.40 , pp. 31-38
    • Scheller, D.1    Kolb, J.2
  • 35
    • 3042593405 scopus 로고    scopus 로고
    • Local inhibition of nitric oxide and prostaglandins independently reduces forearm exercise hyperaemia in humans
    • Schrage WG, Joyner MJ & Dinenno FA (2004). Local inhibition of nitric oxide and prostaglandins independently reduces forearm exercise hyperaemia in humans. J Physiol 557, 599-611.
    • (2004) J Physiol , vol.557 , pp. 599-611
    • Schrage, W.G.1    Joyner, M.J.2    Dinenno, F.A.3
  • 36
    • 33846979103 scopus 로고    scopus 로고
    • Ageing reduces nitric oxide- and prostaglandin-mediated vasodilatation in exercising humans
    • Schrage WG, Eisenach JH & Joyner MJ (2007). Ageing reduces nitric oxide- and prostaglandin-mediated vasodilatation in exercising humans. J Physiol 579, 227-236.
    • (2007) J Physiol , vol.579 , pp. 227-236
    • Schrage, W.G.1    Eisenach, J.H.2    Joyner, M.J.3
  • 37
    • 2442652730 scopus 로고    scopus 로고
    • Effects of ageing and exercise training on endothelium-dependent vasodilatation and structure of rat skeletal muscle arterioles
    • Spier SA, Delp MD, Meininger CJ, Donato AJ, Ramsey MW & Muller-Delp JM (2004). Effects of ageing and exercise training on endothelium-dependent vasodilatation and structure of rat skeletal muscle arterioles. J Physiol 556, 947-958.
    • (2004) J Physiol , vol.556 , pp. 947-958
    • Spier, S.A.1    Delp, M.D.2    Meininger, C.J.3    Donato, A.J.4    Ramsey, M.W.5    Muller-Delp, J.M.6
  • 40
    • 0016029728 scopus 로고
    • Influence of age on the local circulatory adaptation to leg exercise
    • Wahren J, Saltin B, Jorfeldt L & Pernow B (1974). Influence of age on the local circulatory adaptation to leg exercise. Scand J Clin Lab Invest 33, 79-86.
    • (1974) Scand J Clin Lab Invest , vol.33 , pp. 79-86
    • Wahren, J.1    Saltin, B.2    Jorfeldt, L.3    Pernow, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.