Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing

Nature Communications

Volumn 5, Issue , 2014, Pages

  Uchida, Shusaku ^a,b   Martel, Guillaume ^a   Pavlowsky, Alice ^c   Takizawa, Shuichi ^a   Hevi, Charles ^a   Watanabe, Yoshifumi ^b   Kandel, Eric R ^d   Alarcon, Juan Marcos ^c   Shumyatsky, Gleb P ^a  

^a RUTGERS UNIVERSITY   (United States)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

^d Department of Neuroscience Howard Hughes Medical Institute Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; GLUA2 PROTEIN; PACLITAXEL; STATHMIN; TUBULIN; UNCLASSIFIED DRUG; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 2; MICROTUBULE PROTEIN;

ADULT; AGING; BRAIN; LEARNING; MEMORY; MUTATION; PROTEIN; RODENT;

AGING; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; FEAR; LEARNING; MALE; MEMORY; MICROTUBULE; MOUSE; MUTATION; NERVE CELL PLASTICITY; NONHUMAN; PROTEIN DEPHOSPHORYLATION; SYNAPSE; WILD TYPE; ANIMAL; C57BL MOUSE; DEFICIENCY; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; MEMORY DISORDER; MUTANT MOUSE STRAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

AGING; ANIMALS; HIPPOCAMPUS; LEARNING; MALE; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MICROTUBULE PROTEINS; MICROTUBULES; MUTATION; NEURONAL PLASTICITY; RECEPTORS, AMPA; SIGNAL TRANSDUCTION; STATHMIN; TUBULIN;

EID: 84904325387     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5389     Document Type: Article

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