Murine GRPR and stathmin control in opposite directions both cued fear extinction and neural activities of the amygdala and prefrontal cortex

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Martel, Guillaume ^a   Hevi, Charles ^a   Wong, Alexandra ^a   Zushida, Ko ^a   Uchida, Shusaku ^a   Shumyatsky, Gleb P ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIN RELEASING PEPTIDE RECEPTOR; PROTEIN C FOS; STATHMIN; BOMBESIN RECEPTOR;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; BASOLATERAL AMYGDALA; CELL ACTIVITY; CONTROLLED STUDY; DENTATE GYRUS; FEAR; GENE ACTIVITY; GENE INACTIVATION; HIPPOCAMPUS; MALE; MOUSE; MUTANT; NERVE CELL PLASTICITY; NONHUMAN; ONCOGENE C FOS; PREFRONTAL CORTEX; PROTEIN FUNCTION; REGULATORY MECHANISM; REINFORCEMENT; WILD TYPE; ANIMAL; C57BL MOUSE; CONDITIONING; CYTOLOGY; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

ANIMALIA; MURINAE; MUS;

AMYGDALA; ANIMALS; CONDITIONING (PSYCHOLOGY); CUES; EXTINCTION, PSYCHOLOGICAL; FEAR; GENE KNOCKOUT TECHNIQUES; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; NEURONS; PREFRONTAL CORTEX; RECEPTORS, BOMBESIN; STATHMIN;

EID: 84856411172     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030942     Document Type: Article

References (31)

1. Myers KM, Davis M, (2007) Mechanisms of fear extinction. Mol Psychiatry 12: 120-150.
2. Maren S, Quirk GJ, (2004) Neuronal signalling of fear memory. Nat Rev Neurosci 5: 844-852.
3. Herry C, Ferraguti F, Singewald N, Letzkus JJ, Ehrlich I, et al. (2010) Neuronal circuits of fear extinction. Eur J Neurosci 31: 599-612.
4. Herry C, Ciocchi S, Senn V, Demmou L, Muller C, et al. (2008) Switching on and off fear by distinct neuronal circuits. Nature 454: 600-606.
5. Herry C, Trifilieff P, Micheau J, Luthi A, Mons N, (2006) Extinction of auditory fear conditioning requires MAPK/ERK activation in the basolateral amygdala. Eur J Neurosci 24: 261-269.
6. Sierra-Mercado D, Padilla-Coreano N, Quirk GJ, (2011) Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear. Neuropsychopharmacology 36: 529-538.
7. Pape HC, Pare D, (2010) Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear. Physiol Rev 90: 419-463.
8. Maren S, (2011) Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory. Neuron 70: 830-845.
9. Frielingsdorf H, Bath KG, Soliman F, Difede J, Casey BJ, et al. (2010) Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. Ann N Y Acad Sci 1208: 150-157.
10. Shumyatsky GP, Malleret G, Shin RM, Takizawa S, Tully K, et al. (2005) stathmin, a gene enriched in the amygdala, controls both learned and innate fear. Cell 123: 697-709.
11. Shumyatsky GP, Tsvetkov E, Malleret G, Vronskaya S, Hatton M, et al. (2002) Identification of a signaling network in lateral nucleus of amygdala important for inhibiting memory specifically related to learned fear. Cell 111: 905-918.
12. Kamichi S, Wada E, Aoki S, Sekiguchi M, Kimura I, et al. (2005) Immunohistochemical localization of gastrin-releasing peptide receptor in the mouse brain. Brain Res 1032: 162-170.
13. Lee K, Dixon AK, Gonzalez I, Stevens EB, McNulty S, et al. (1999) Bombesin-like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors. J Physiol 518 (Pt 3): 791-802.
14. Amat JA, Fields KL, Schubart UK, (1991) Distribution of phosphoprotein p19 in rat brain during ontogeny: stage-specific expression in neurons and glia. Brain Res Dev Brain Res 60: 205-218.
15. Martel G, Nishi A, Shumyatsky GP, (2008) Stathmin reveals dissociable roles of the basolateral amygdala in parental and social behaviors. Proc Natl Acad Sci U S A 105: 14620-14625.
16. Han JH, Yiu AP, Cole CJ, Hsiang HL, Neve RL, et al. (2008) Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear. Learn Mem 15: 443-453.
17. Sangha S, Narayanan RT, Bergado-Acosta JR, Stork O, Seidenbecher T, et al. (2009) Deficiency of the 65 kDa isoform of glutamic acid decarboxylase impairs extinction of cued but not contextual fear memory. J Neurosci 29: 15713-15720.
18. Stork O, Yamanaka H, Stork S, Kume N, Obata K, (2003) Altered conditioned fear behavior in glutamate decarboxylase 65 null mutant mice. Genes Brain Behav 2: 65-70.
19. Stork O, Ji FY, Kaneko K, Stork S, Yoshinobu Y, et al. (2000) Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65. Brain Res 865: 45-58.
20. Kash SF, Tecott LH, Hodge C, Baekkeskov S, (1999) Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A 96: 1698-1703.
21. Yee BK, Hauser J, Dolgov VV, Keist R, Mohler H, et al. (2004) GABA receptors containing the alpha5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear. Eur J Neurosci 20: 1928-1936.
22. Ehrlich I, Humeau Y, Grenier F, Ciocchi S, Herry C, et al. (2009) Amygdala inhibitory circuits and the control of fear memory. Neuron 62: 757-771.
23. Plendl W, Wotjak CT, (2010) Dissociation of within- and between-session extinction of conditioned fear. J Neurosci 30: 4990-4998.
24. Thompson BM, Baratta MV, Biedenkapp JC, Rudy JW, Watkins LR, et al. (2010) Activation of the infralimbic cortex in a fear context enhances extinction learning. Learn Mem 17: 591-599.
25. Knapska E, Maren S, (2009) Reciprocal patterns of c-Fos expression in the medial prefrontal cortex and amygdala after extinction and renewal of conditioned fear. Learn Mem 16: 486-493.
26. Lattal KM, Stafford JM, (2008) What does it take to demonstrate memory erasure? Theoretical comment on Norrholmet al. (2008). Behav Neurosci 122: 1186-1190.
27. Brocke B, Lesch KP, Armbruster D, Moser DA, Muller A, et al. (2010) Stathmin, a gene regulating neural plasticity, affects fear and anxiety processing in humans. Am J Med Genet B Neuropsychiatr Genet 153B: 243-251.
28. Uchida S, Hara K, Kobayashi A, Funato H, Hobara T, et al. (2010) Early life stress enhances behavioral vulnerability to stress through the activation of REST4-mediated gene transcription in the medial prefrontal cortex of rodents. J Neurosci 30: 15007-15018.
29. Uchida S, Hara K, Kobayashi A, Otsuki K, Yamagata H, et al. (2011) Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events. Neuron 69: 359-372.
30. Uchida S, Hara K, Kobayashi A, Fujimoto M, Otsuki K, et al. (2011) Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1. Proc Natl Acad Sci U S A 108: 1681-1686.
31. Paxinos G, Franklin KBJ, (2001) The mouse brain in stereotaxic coordinates San Diego Academic Pressxxv, 1 v. (various pagings).