메뉴 건너뛰기




Volumn 35, Issue 10, 2011, Pages 1395-1401

Dequalinium induces human leukemia cell death by affecting the redox balance

Author keywords

Antitumoral; Apoptosis; Dequalinium; DQAsomes; Glutathione; JNK; Leukemia; P38

Indexed keywords

DEQUALINIUM; GLUTATHIONE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

EID: 80052090483     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2011.03.012     Document Type: Article
Times cited : (21)

References (40)
  • 1
    • 77953131908 scopus 로고    scopus 로고
    • Targeting mitochondria for cancer therapy. Nat Rev Drug Discov; May 14.
    • Fulda S, Galluzzi L, Kroemer G. Targeting mitochondria for cancer therapy. Nat Rev Drug Discov 2010; May 14.
    • (2010)
    • Fulda, S.1    Galluzzi, L.2    Kroemer, G.3
  • 2
    • 49149124239 scopus 로고    scopus 로고
    • Nanocarrier-assisted subcellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel
    • D'Souza G.G.M., Cheng S.M., Boddapati S.V., Horobin R.W., Weissig V. Nanocarrier-assisted subcellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel. J Drug Target 2008, 16(7):578-585.
    • (2008) J Drug Target , vol.16 , Issue.7 , pp. 578-585
    • D'Souza, G.G.M.1    Cheng, S.M.2    Boddapati, S.V.3    Horobin, R.W.4    Weissig, V.5
  • 3
    • 0035797118 scopus 로고    scopus 로고
    • Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells
    • Modica-Napolitano J.S., Aprille J.R. Delocalized lipophilic cations selectively target the mitochondria of carcinoma cells. Adv Drug Deliver Rev 2001, 49:63-70.
    • (2001) Adv Drug Deliver Rev , vol.49 , pp. 63-70
    • Modica-Napolitano, J.S.1    Aprille, J.R.2
  • 4
    • 0142122108 scopus 로고    scopus 로고
    • The selective in vitro cytotoxicity of carcinoma cells by AZT is enhanced by concurrent treatment with delocalized lipophilic cations
    • Modica-Napolitano J.S., Nalbandian R., Kidd M.E., Nalbandian A., Nguyen C.C. The selective in vitro cytotoxicity of carcinoma cells by AZT is enhanced by concurrent treatment with delocalized lipophilic cations. Cancer Lett 2003, 198:59-68.
    • (2003) Cancer Lett , vol.198 , pp. 59-68
    • Modica-Napolitano, J.S.1    Nalbandian, R.2    Kidd, M.E.3    Nalbandian, A.4    Nguyen, C.C.5
  • 5
    • 0031683986 scopus 로고    scopus 로고
    • Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity
    • Weissig V., Lizano C., Torchilin V. Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity. J Liposome Res 1998, 8:391-400.
    • (1998) J Liposome Res , vol.8 , pp. 391-400
    • Weissig, V.1    Lizano, C.2    Torchilin, V.3
  • 6
    • 0027420209 scopus 로고
    • Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro
    • Helige C., Smolle J., Zellnig G., Fink-Puches R., Kerl H., Tritthart H.A. Effect of dequalinium on K1735-M2 melanoma cell growth, directional migration and invasion in vitro. Eur J Cancer 1992, 29A:124-128.
    • (1992) Eur J Cancer , vol.29 A , pp. 124-128
    • Helige, C.1    Smolle, J.2    Zellnig, G.3    Fink-Puches, R.4    Kerl, H.5    Tritthart, H.A.6
  • 7
    • 0036883688 scopus 로고    scopus 로고
    • Expression and activity of potassium ion channels in human prostate cancer
    • Abdul M., Hoosein N. Expression and activity of potassium ion channels in human prostate cancer. Cancer Lett 2002, 186:99-105.
    • (2002) Cancer Lett , vol.186 , pp. 99-105
    • Abdul, M.1    Hoosein, N.2
  • 8
    • 0025037276 scopus 로고
    • Study of the selective cytotoxic properties of cationic, lipophilic mitochondrial-specific compounds in gynecologic malignancies
    • Christman J.E., Miller D.S., Coward P., Smith L.H., Teng N. Study of the selective cytotoxic properties of cationic, lipophilic mitochondrial-specific compounds in gynecologic malignancies. Gynecol Oncol 1990, 39:72-79.
    • (1990) Gynecol Oncol , vol.39 , pp. 72-79
    • Christman, J.E.1    Miller, D.S.2    Coward, P.3    Smith, L.H.4    Teng, N.5
  • 9
    • 77949439646 scopus 로고    scopus 로고
    • Dasatinib in chronic myeloid leukemia: a review
    • Aguilera D.G., Tsimberidou A.M. Dasatinib in chronic myeloid leukemia: a review. Ther Clin Risk Manag 2009, 5(2):281-289.
    • (2009) Ther Clin Risk Manag , vol.5 , Issue.2 , pp. 281-289
    • Aguilera, D.G.1    Tsimberidou, A.M.2
  • 10
    • 42549133659 scopus 로고    scopus 로고
    • Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia
    • Chen J., McMillan N.A. Molecular basis of pathogenesis, prognosis and therapy in chronic lymphocytic leukaemia. Cancer Biol Ther 2008, 7(2):174-179.
    • (2008) Cancer Biol Ther , vol.7 , Issue.2 , pp. 174-179
    • Chen, J.1    McMillan, N.A.2
  • 11
    • 0021674862 scopus 로고
    • An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity
    • Konopka J.B., Watanabe S.M., Witte O.N. An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 1984, 37:1035-1042.
    • (1984) Cell , vol.37 , pp. 1035-1042
    • Konopka, J.B.1    Watanabe, S.M.2    Witte, O.N.3
  • 12
    • 27144515283 scopus 로고    scopus 로고
    • Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds
    • Aichberger K.J., Mayerhofer M., Krauth M.T., Vales A., Kondo R., Derdak S., et al. Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds. Cancer Res 2005, 65(20):9436-9444.
    • (2005) Cancer Res , vol.65 , Issue.20 , pp. 9436-9444
    • Aichberger, K.J.1    Mayerhofer, M.2    Krauth, M.T.3    Vales, A.4    Kondo, R.5    Derdak, S.6
  • 13
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • McCubrey J.A., Steelman L.S., Chappell W.H., Abrams S.L., Wong E.W., Chang F., et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007, 1773(8):1263-1284.
    • (2007) Biochim Biophys Acta , vol.1773 , Issue.8 , pp. 1263-1284
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3    Abrams, S.L.4    Wong, E.W.5    Chang, F.6
  • 14
    • 33749337234 scopus 로고    scopus 로고
    • Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia
    • Kornblau S.M., Womble M., Qiu Y.H., Jackson C.E., Chen W., Konopleva M., et al. Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia. Blood 2006, 108(7):2358-2365.
    • (2006) Blood , vol.108 , Issue.7 , pp. 2358-2365
    • Kornblau, S.M.1    Womble, M.2    Qiu, Y.H.3    Jackson, C.E.4    Chen, W.5    Konopleva, M.6
  • 15
    • 37249084066 scopus 로고    scopus 로고
    • Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors
    • Champelovier P., El Atifi M., Pautre V., Rostaing B., Berger F., Seigneurin D. Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors. Exp Hematol 2008, 36(1):28-36.
    • (2008) Exp Hematol , vol.36 , Issue.1 , pp. 28-36
    • Champelovier, P.1    El Atifi, M.2    Pautre, V.3    Rostaing, B.4    Berger, F.5    Seigneurin, D.6
  • 16
    • 9144253936 scopus 로고    scopus 로고
    • The ASK1-MAP kinase cascades in mammalian stress response
    • Matsukawa J., Matsuzawa A., Takeda K., Ichijo H. The ASK1-MAP kinase cascades in mammalian stress response. J Biochem 2004, 136(3):261-265.
    • (2004) J Biochem , vol.136 , Issue.3 , pp. 261-265
    • Matsukawa, J.1    Matsuzawa, A.2    Takeda, K.3    Ichijo, H.4
  • 17
    • 38349049487 scopus 로고    scopus 로고
    • S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response
    • Townsend D.M. S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. Mol Interv 2007, 7(6):313-324.
    • (2007) Mol Interv , vol.7 , Issue.6 , pp. 313-324
    • Townsend, D.M.1
  • 18
    • 42749096619 scopus 로고    scopus 로고
    • Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells
    • Moon D.O., Kim M.O., Choi Y.H., Kim N.D., Chang J.H., Kim G.Y. Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells. Cancer Lett 2008, 264(2):316-325.
    • (2008) Cancer Lett , vol.264 , Issue.2 , pp. 316-325
    • Moon, D.O.1    Kim, M.O.2    Choi, Y.H.3    Kim, N.D.4    Chang, J.H.5    Kim, G.Y.6
  • 19
    • 60149093582 scopus 로고    scopus 로고
    • Non-classical p38 map kinase functions: cell cycle checkpoints and survival
    • Thornton T.M., Rincon M. Non-classical p38 map kinase functions: cell cycle checkpoints and survival. Int J Biol Sci 2009, 5(1):44-51.
    • (2009) Int J Biol Sci , vol.5 , Issue.1 , pp. 44-51
    • Thornton, T.M.1    Rincon, M.2
  • 20
    • 34248597065 scopus 로고    scopus 로고
    • Differential regulation and properties of MAPKs
    • Raman M., Chen W., Cobb M.H. Differential regulation and properties of MAPKs. Oncogene 2007, 26(22):3100-3112.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3100-3112
    • Raman, M.1    Chen, W.2    Cobb, M.H.3
  • 22
    • 70349172938 scopus 로고    scopus 로고
    • Apoptosis and glutathione: beyond an antioxidant
    • Franco R., Cidlowski J.A. Apoptosis and glutathione: beyond an antioxidant. Cell Death Differ 2009, 16(10):1303-1314.
    • (2009) Cell Death Differ , vol.16 , Issue.10 , pp. 1303-1314
    • Franco, R.1    Cidlowski, J.A.2
  • 23
    • 23844554815 scopus 로고    scopus 로고
    • Effects of the antitumoral Dequalinium on NB4 and K562 leukemia cell lines. Mitochondrial implication in cell death
    • Galeano E., Nieto E., García-Pérez A.I., Delgado M.D., Pinilla M., Sancho P. Effects of the antitumoral Dequalinium on NB4 and K562 leukemia cell lines. Mitochondrial implication in cell death. Leuk Res 2005, 29(10):1201-1211.
    • (2005) Leuk Res , vol.29 , Issue.10 , pp. 1201-1211
    • Galeano, E.1    Nieto, E.2    García-Pérez, A.I.3    Delgado, M.D.4    Pinilla, M.5    Sancho, P.6
  • 24
    • 34249814317 scopus 로고    scopus 로고
    • Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production
    • Sancho P., Galeano E., Nieto E., Delgado M.D., García-Pérez A.I. Dequalinium induces cell death in human leukemia cells by early mitochondrial alterations which enhance ROS production. Leuk Res 2007, 31(7):969-978.
    • (2007) Leuk Res , vol.31 , Issue.7 , pp. 969-978
    • Sancho, P.1    Galeano, E.2    Nieto, E.3    Delgado, M.D.4    García-Pérez, A.I.5
  • 25
    • 0036644215 scopus 로고    scopus 로고
    • Regulation and measurement of oxidative stress in apoptosis
    • Curtin J.F., Donovan M., Cotter T.G. Regulation and measurement of oxidative stress in apoptosis. J Immunol Methods 2002, 265:49-72.
    • (2002) J Immunol Methods , vol.265 , pp. 49-72
    • Curtin, J.F.1    Donovan, M.2    Cotter, T.G.3
  • 27
    • 2942593991 scopus 로고    scopus 로고
    • ROS stress in cancer cells and therapeutic implications
    • Pelicano H., Carney D., Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Updat 2004, 7:97-110.
    • (2004) Drug Resist Updat , vol.7 , pp. 97-110
    • Pelicano, H.1    Carney, D.2    Huang, P.3
  • 28
    • 39749106934 scopus 로고    scopus 로고
    • NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells
    • Wang J., Li L., Cang H., Shi G., Yi J. NADPH oxidase-derived reactive oxygen species are responsible for the high susceptibility to arsenic cytotoxicity in acute promyelocytic leukemia cells. Leuk Res 2008, 32(3):429-436.
    • (2008) Leuk Res , vol.32 , Issue.3 , pp. 429-436
    • Wang, J.1    Li, L.2    Cang, H.3    Shi, G.4    Yi, J.5
  • 29
    • 77649185802 scopus 로고    scopus 로고
    • NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability
    • Miyoshi T., Arai T., Yamashita K., Sasada M., Uchiyama T. NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability. Leuk Res 2010, 34(3):373-378.
    • (2010) Leuk Res , vol.34 , Issue.3 , pp. 373-378
    • Miyoshi, T.1    Arai, T.2    Yamashita, K.3    Sasada, M.4    Uchiyama, T.5
  • 30
    • 67650312376 scopus 로고    scopus 로고
    • Sodium selenite induces apoptosis in acute promyelocytic leukemia-derived NB4 cells through mitochondria-dependent pathway
    • Han B., Ren Y., Guan L., Wei W., Hua F., Yang Y., et al. Sodium selenite induces apoptosis in acute promyelocytic leukemia-derived NB4 cells through mitochondria-dependent pathway. Oncol Res 2009, 17(8):373-381.
    • (2009) Oncol Res , vol.17 , Issue.8 , pp. 373-381
    • Han, B.1    Ren, Y.2    Guan, L.3    Wei, W.4    Hua, F.5    Yang, Y.6
  • 31
    • 47249154397 scopus 로고    scopus 로고
    • Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK AMPK)
    • Sánchez Y., Amrán D., Fernández C., de Blas E., Aller P. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK AMPK). Int J Cancer 2008, 123(5):1205-1214.
    • (2008) Int J Cancer , vol.123 , Issue.5 , pp. 1205-1214
    • Sánchez, Y.1    Amrán, D.2    Fernández, C.3    de Blas, E.4    Aller, P.5
  • 32
    • 42649083649 scopus 로고    scopus 로고
    • Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines
    • Ramos A.M., Aller P. Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines. Biochem Pharmacol 2008, 75(10):1912-1923.
    • (2008) Biochem Pharmacol , vol.75 , Issue.10 , pp. 1912-1923
    • Ramos, A.M.1    Aller, P.2
  • 33
    • 0042164447 scopus 로고    scopus 로고
    • The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells
    • Troyano A., Sancho P., Fernández C., de Blas E., Bernardi P., Aller P. The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells. Cell Death Differ 2003, 10(8):889-898.
    • (2003) Cell Death Differ , vol.10 , Issue.8 , pp. 889-898
    • Troyano, A.1    Sancho, P.2    Fernández, C.3    de Blas, E.4    Bernardi, P.5    Aller, P.6
  • 34
    • 80052471102 scopus 로고    scopus 로고
    • Knockdown of SOD1 sensitizes the CD34+ CML cells to imatinib therapy
    • Epub ahead of print
    • Liu L., Chen R., Huang S., Wu Y., Li G., Liu Q., et al. Knockdown of SOD1 sensitizes the CD34+ CML cells to imatinib therapy. Med Oncol 2010 Apr, 21. Epub ahead of print.
    • (2010) Med Oncol , vol.21
    • Liu, L.1    Chen, R.2    Huang, S.3    Wu, Y.4    Li, G.5    Liu, Q.6
  • 35
    • 84861593501 scopus 로고    scopus 로고
    • Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia
    • Pajuelo L., Calviño E., Diez J.C., Boyano-Adánez M.C., Gil J., Sancho P. Dequalinium induces apoptosis in peripheral blood mononuclear cells isolated from human chronic lymphocytic leukemia. Invest New Drugs 2010 Jun, 5.
    • (2010) Invest New Drugs , pp. 5
    • Pajuelo, L.1    Calviño, E.2    Diez, J.C.3    Boyano-Adánez, M.C.4    Gil, J.5    Sancho, P.6
  • 36
    • 16544386770 scopus 로고    scopus 로고
    • The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of reactive oxygen species
    • Gao F., Yi J., Yuan J.Q., Shi G.Y., Tang X.M. The cell cycle related apoptotic susceptibility to arsenic trioxide is associated with the level of reactive oxygen species. Cell Res 2004, 14(1):81-85.
    • (2004) Cell Res , vol.14 , Issue.1 , pp. 81-85
    • Gao, F.1    Yi, J.2    Yuan, J.Q.3    Shi, G.Y.4    Tang, X.M.5
  • 37
    • 0342460503 scopus 로고    scopus 로고
    • Differentiation of U-937 promonocytic cells by etoposide and ICRF-193, two antitumour DNA topoisomerase II inhibitors with different mechanisms of action
    • Pérez C., Vilaboa N.E., García-Bermejo L., de Blas E., Creighton A.M., Aller P. Differentiation of U-937 promonocytic cells by etoposide and ICRF-193, two antitumour DNA topoisomerase II inhibitors with different mechanisms of action. J Cell Sci 1997, 110:337-343.
    • (1997) J Cell Sci , vol.110 , pp. 337-343
    • Pérez, C.1    Vilaboa, N.E.2    García-Bermejo, L.3    de Blas, E.4    Creighton, A.M.5    Aller, P.6
  • 38
    • 49749123870 scopus 로고    scopus 로고
    • A new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2
    • Kasukabe T., Okabe-Kado J., Honma Y., Cotylenin A. a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2. Cancer Sci 2008, 99(8):1693-1698.
    • (2008) Cancer Sci , vol.99 , Issue.8 , pp. 1693-1698
    • Kasukabe, T.1    Okabe-Kado, J.2    Honma, Y.3    Cotylenin, A.4
  • 39
    • 38649102191 scopus 로고    scopus 로고
    • Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives
    • Viola G., Vedaldi D., Dall'Acqua F., Fortunato E., Basso G., Bianchi N., et al. Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives. Biochem Pharmacol 2008, 75(4):810-825.
    • (2008) Biochem Pharmacol , vol.75 , Issue.4 , pp. 810-825
    • Viola, G.1    Vedaldi, D.2    Dall'Acqua, F.3    Fortunato, E.4    Basso, G.5    Bianchi, N.6
  • 40
    • 65249103361 scopus 로고    scopus 로고
    • Involvement of p38 and c-Jun N-terminal protein kinase in cardiotoxin III-induced apoptosis of K562 cells
    • Chen X.Y., Yang H.X., Qu S.F., Liu J., Lv P., Xu J.P., et al. Involvement of p38 and c-Jun N-terminal protein kinase in cardiotoxin III-induced apoptosis of K562 cells. Biol Pharm Bull 2009, 32(4):583-588.
    • (2009) Biol Pharm Bull , vol.32 , Issue.4 , pp. 583-588
    • Chen, X.Y.1    Yang, H.X.2    Qu, S.F.3    Liu, J.4    Lv, P.5    Xu, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.