In vivo evidence for nitric oxide-mediated calcium-activated potassium-channel activation during human endotoxemia

Circulation

Volumn 114, Issue 5, 2006, Pages 414-421

  Pickkers, Peter ^a   Dorresteijn, Mirrin J ^a   Bouw, Martijn P W J M ^a   Van Der Hoeven, Johannes G ^a   Smits, Paul ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Inflammation; Ion channels; Nitric oxide synthase; Pharmacology; Regional blood flow; Vasoconstriction

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; ESCHERICHIA COLI ENDOTOXIN; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; NORADRENALIN; POTASSIUM CHANNEL BLOCKING AGENT; TETRYLAMMONIUM; ENDOTOXIN; ENDOTOXIN, ESCHERICHIA COLI; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE; TOLBUTAMIDE;

ADULT; ARTICLE; BLOOD FLOW; BRACHIAL ARTERY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTOXEMIA; ESCHERICHIA COLI; FEMALE; FOREARM BLOOD FLOW; HUMAN; IN VIVO STUDY; MALE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; VASOCONSTRICTION; VEIN OCCLUSION PLETHYSMOGRAPHY; CLINICAL TRIAL; DOSE RESPONSE; DRUG ANTAGONISM; ENTEROBACTER INFECTION; FOREARM; HEMODYNAMICS; INFLAMMATION; PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULARIZATION;

ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXEMIA; ENDOTOXINS; ENZYME INHIBITORS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; FOREARM; HEMODYNAMIC PROCESSES; HUMANS; INFLAMMATION; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; OMEGA-N-METHYLARGININE; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; REGIONAL BLOOD FLOW; TETRAETHYLAMMONIUM; TOLBUTAMIDE; VASOCONSTRICTION;

EID: 33747087878     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.590232     Document Type: Article

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