-
1
-
-
84893235639
-
-
United States Department of Health and Human Services. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health
-
United States Department of Health and Human Services. The Health Consequences of Smoking: 50 Years of Progress. A Report of the Surgeon General. Atlanta, GA: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 2014.
-
(2014)
The Health Consequences of Smoking: 50 Years of Progress. A Report of the Surgeon General
-
-
-
2
-
-
84961004853
-
The production of malignant primary hepatic tumors in the rat by feeding dimethylnitrosamine
-
Magee PN, Barnes JM. The production of malignant primary hepatic tumors in the rat by feeding dimethylnitrosamine. Br J Cancer 1956;10:114-22.
-
(1956)
Br J Cancer
, vol.10
, pp. 114-122
-
-
Magee, P.N.1
Barnes, J.M.2
-
3
-
-
0014188061
-
Organotrope Carcinogen Wirkungen bei 65 verschiedenen N-Nitrosoverbindungen an BD-ratten
-
Druckrey H, Preussmann R, Ivankovic S, Schmähl D. Organotrope Carcinogen Wirkungen bei 65 verschiedenen N-Nitrosoverbindungen an BD-ratten. Z Krebsforsch Klin Onkol 1967;69:103-201.
-
(1967)
Z Krebsforsch Klin Onkol
, vol.69
, pp. 103-201
-
-
Druckrey, H.1
Preussmann, R.2
Ivankovic, S.3
Schmähl, D.4
-
4
-
-
0002624810
-
N-nitroso carcinogens
-
Searle C, editor. Chemical carcinogens. 2nd ed., Vol 2. Washington, DC: American Chemical Society
-
Preussmann R, Stewart BW. N-nitroso carcinogens. In: Searle C, editor. Chemical carcinogens. 2nd ed., Vol 2. ACS Monograph 182. Washington, DC: American Chemical Society; 1981. p. 643-828.
-
(1981)
ACS Monograph
, vol.182
, pp. 643-828
-
-
Preussmann, R.1
Stewart, B.W.2
-
5
-
-
0001348856
-
Chemistry and Biology of N-nitroso compounds
-
Cambridge, UK: Cambridge University Press
-
Lijinsky W. Chemistry and Biology of N-nitroso compounds. In: Cambridge monographs on cancer research. Cambridge, UK: Cambridge University Press; 1992. p. 251-403.
-
(1992)
Cambridge Monographs on Cancer Research
, pp. 251-403
-
-
Lijinsky, W.1
-
6
-
-
0019457427
-
Animal species in which N-nitroso compounds induce cancer
-
DOI 10.1002/ijc.2910270408
-
Bogovski P, Bogovski S. Animal species in which N-nitroso compounds induce cancer. Int J Cancer 1981;27:471-4. (Pubitemid 11159732)
-
(1981)
International Journal of Cancer
, vol.27
, Issue.4
, pp. 471-474
-
-
Bogovski, P.1
Bogovski, S.2
-
7
-
-
0026347782
-
Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: A detailed dose-response study
-
Peto R, Gray R, Brantom P, Grasso P. Effects on 4080 rats of chronic ingestion of N-nitrosodiethylamine or N-nitrosodimethylamine: a detailed dose-response study. Cancer Res 1991;51:6415-51.
-
(1991)
Cancer Res
, vol.51
, pp. 6415-6451
-
-
Peto, R.1
Gray, R.2
Brantom, P.3
Grasso, P.4
-
8
-
-
76549257892
-
Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma. A study of six hundred and eighty-four proved cases
-
Wynder EL, Graham EA. Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma. A study of six hundred and eighty-four proved cases. J Am Med Assoc 1950;143:329-36.
-
(1950)
J Am Med Assoc
, vol.143
, pp. 329-336
-
-
Wynder, E.L.1
Graham, E.A.2
-
9
-
-
0008376153
-
Smoking and carcinoma of the lung: A preliminary report
-
Doll R, Hill AB. Smoking and carcinoma of the lung: a preliminary report. Br Med J 1950;ii:739-48.
-
(1950)
Br Med J
, vol.2
, pp. 739-748
-
-
Doll, R.1
Hill, A.B.2
-
10
-
-
0010490441
-
Induction of pulmonary tumours in mice by nitrosonornicotine, a possible constituent of tobacco smoke
-
Boyland E, Roe FJC, Gorrod JW. Induction of pulmonary tumours in mice by nitrosonornicotine, a possible constituent of tobacco smoke. Nature 1964;202:1126.
-
(1964)
Nature
, vol.202
, pp. 1126
-
-
Boyland, E.1
Roe, F.J.C.2
Gorrod, J.W.3
-
11
-
-
0016803076
-
Effects of N′-nitrosonornicotine and N′-nitrosoanabasine in rats
-
Hoffmann D, Raineri R, Hecht SS, Maronpot R, Wynder EL. Effects of N′-nitrosonornicotine and N′-nitrosoanabasine in rats. J Natl Cancer Inst 1975;55:977-81.
-
(1975)
J Natl Cancer Inst
, vol.55
, pp. 977-981
-
-
Hoffmann, D.1
Raineri, R.2
Hecht, S.S.3
Maronpot, R.4
Wynder, E.L.5
-
12
-
-
0018889232
-
Comparative carcinogenicity in F344 rats of the tobacco-specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl) 1-butanone
-
Hecht SS, Chen CB, Ohmori T, Hoffmann D. Comparative carcinogenicity in F344 rats of the tobacco specific nitrosamines, N′-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Res 1980;40:298-302. (Pubitemid 10140152)
-
(1980)
Cancer Research
, vol.40
, Issue.2
, pp. 298-302
-
-
Hecht, S.S.1
Chen, C.B.2
Ohmori, T.3
Hoffmann, D.4
-
13
-
-
0018096625
-
Tobacco- specific nitrosamines:formation from nicotine in vitro and during tobacco curing and carcinogenicity in strain A mice
-
Hecht SS, Chen CB, Hirota N, Ornaf RM, Tso TC, Hoffmann D. Tobacco specific nitrosamines: formation from nicotine in vitro and during tobacco curing and carcinogenicity in strain A mice. J Natl Cancer Inst 1978;60:819-24. (Pubitemid 8331120)
-
(1978)
Journal of the National Cancer Institute
, vol.60
, Issue.4
, pp. 819-824
-
-
Hecht, S.S.1
Chen C.-hong, H.B.N.2
-
14
-
-
39749170291
-
Smokeless tobacco and tobacco-specific nitrosamines
-
International Agency for Research on Cancer. Lyon, FR: IARC
-
International Agency for Research on Cancer. Smokeless tobacco and tobacco-specific nitrosamines. In: IARC monographs on the evaluation of carcinogenic risks to humans. Vol. 89. Lyon, FR: IARC; 2007. p. 421-583.
-
(2007)
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
, vol.89
, pp. 421-583
-
-
-
15
-
-
0031831381
-
Biochemistry, biology, and carcinogenicity of tobacco-specific N- nitrosamines
-
DOI 10.1021/tx980005y
-
Hecht SS. Biochemistry, biology, and carcinogenicity of tobacco-specific N-nitrosamines. Chem Res Toxicol 1998;11:559-603. (Pubitemid 28285583)
-
(1998)
Chemical Research in Toxicology
, vol.11
, Issue.6
, pp. 559-603
-
-
Hecht, S.S.1
-
16
-
-
0025297169
-
6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone. Cancer Res 1990; 50:3772-80.
-
(1990)
Cancer Res
, vol.50
, pp. 3772-3780
-
-
Belinsky, S.A.1
Foley, J.F.2
White, C.M.3
Anderson, M.W.4
Maronpot, R.R.5
-
17
-
-
0024262907
-
Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines
-
Rivenson A, Hoffmann D, Prokopczyk B, Amin S, Hecht SS. Induction of lung and exocrine pancreas tumors in F344 rats by tobacco-specific and Areca-derived N-nitrosamines. Cancer Res 1988;48:6912-7. (Pubitemid 19012226)
-
(1988)
Cancer Research
, vol.48
, Issue.23
, pp. 6912-6917
-
-
Rivenson, A.1
Hoffmann, D.2
Prokopczyk, B.3
Amin, S.4
Hecht, S.S.5
-
18
-
-
70349558869
-
Population estimates for biomarkers of exposure to cigarette smoke in adult U.S. cigarette smokers
-
Roethig HJ, Munjal S, Feng S, Liang Q, Sarkar M, Walk RA, et al. Population estimates for biomarkers of exposure to cigarette smoke in adult U.S. cigarette smokers. Nicotine Tob Res 2009;11:1216-25.
-
(2009)
Nicotine Tob Res
, vol.11
, pp. 1216-1225
-
-
Roethig, H.J.1
Munjal, S.2
Feng, S.3
Liang, Q.4
Sarkar, M.5
Walk, R.A.6
-
19
-
-
80051968583
-
The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is signi ficantly higher in passive than in active smokers
-
Vogel RI, Carmella SG, Stepanov I, Hatsukami DK, Hecht SS. The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is signi ficantly higher in passive than in active smokers. Biomarkers 2011;16:491-7.
-
(2011)
Biomarkers
, vol.16
, pp. 491-497
-
-
Vogel, R.I.1
Carmella, S.G.2
Stepanov, I.3
Hatsukami, D.K.4
Hecht, S.S.5
-
20
-
-
79951913809
-
Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol (NNAL) in smokers in the United States: NHANES 2007-2008
-
Xia Y, Bernert JT, Jain RB, Ashley DL, Pirkle JL. Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008. Biomarkers 2011;16:112-9.
-
(2011)
Biomarkers
, vol.16
, pp. 112-119
-
-
Xia, Y.1
Bernert, J.T.2
Jain, R.B.3
Ashley, D.L.4
Pirkle, J.L.5
-
21
-
-
53549092523
-
Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers
-
Stepanov I, Upadhyaya P, Feuer R, Jensen J, Hatsukami DK, Hecht SS. Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers. Cancer Epidemiol Biomarkers Prev 2008;17:1764-73.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 1764-1773
-
-
Stepanov, I.1
Upadhyaya, P.2
Feuer, R.3
Jensen, J.4
Hatsukami, D.K.5
Hecht, S.S.6
-
22
-
-
84877812583
-
TSNA levels in machine-generated mainstream cigarette smoke: 35 years of data
-
Appleton S, Olegario RM, Lipowicz PJ. TSNA levels in machine-generated mainstream cigarette smoke: 35 years of data. Regul Toxicol Pharmacol 2013;66:197-207.
-
(2013)
Regul Toxicol Pharmacol
, vol.66
, pp. 197-207
-
-
Appleton, S.1
Olegario, R.M.2
Lipowicz, P.J.3
-
23
-
-
84857030295
-
Carcinogenic tobacco-specific N-nitrosamines in U.S. cigarettes: Three decades of remarkable neglect by the tobacco industry
-
Stepanov I, Knezevich A, Zhang L, Watson CH, Hatsukami DK, Hecht SS. Carcinogenic tobacco-specific N-nitrosamines in U.S. cigarettes: three decades of remarkable neglect by the tobacco industry. Tob Control 2012;21:44-8.
-
(2012)
Tob Control
, vol.21
, pp. 44-48
-
-
Stepanov, I.1
Knezevich, A.2
Zhang, L.3
Watson, C.H.4
Hatsukami, D.K.5
Hecht, S.S.6
-
24
-
-
40449086665
-
Dose translation from animal to human studies revisited
-
DOI 10.1096/fj.07-9574LSF
-
Reagan-Shaw S, Nihal M, Ahmad N. Dose translation from animal to human studies revisited. FASEB J 2008;22:659-61. (Pubitemid 351348146)
-
(2008)
FASEB Journal
, vol.22
, Issue.3
, pp. 659-661
-
-
Reagan-Shaw, S.1
Nihal, M.2
Ahmad, N.3
-
25
-
-
84886666568
-
(S)-N′-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats
-
Balbo S, James-Yi S, Johnson CS, O'Sullivan G, Stepanov I, Wang M, et al. (S)-N′-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats. Carcinogenesis 2013;34:2178-83.
-
(2013)
Carcinogenesis
, vol.34
, pp. 2178-2183
-
-
Balbo, S.1
James-Yi, S.2
Johnson, C.S.3
O'Sullivan, G.4
Stepanov, I.5
Wang, M.6
-
26
-
-
0032439956
-
Inhibition of N'-nitrosonornicotine-induced esophageal tumorigenesis by 3-phenylpropyl isothiocyanate
-
DOI 10.1093/carcin/19.12.2139
-
Stoner GD, Adams C, Kresty LA, Hecht SS, Murphy SE, Morse MA. Inhibition of N′-nitrosonornicotine-induced esophageal tumorigenesis by 3-phenylpropyl isothiocyanate. Carcinogenesis 1998;19:2139-43. (Pubitemid 29010253)
-
(1998)
Carcinogenesis
, vol.19
, Issue.12
, pp. 2139-2143
-
-
Stoner, G.D.1
Adams, C.2
Kresty, L.A.3
Amin, S.G.4
Desai, D.5
Hecht, S.S.6
Murphy, S.E.7
Morsc, M.A.8
-
27
-
-
84904326429
-
-
National Institute of Environmental Health Sciences and National Toxicology Program [cited 2014 Mar 12]. Available from
-
National Institute of Environmental Health Sciences and National Institutes of Health. National Toxicology Program [cited 2014 Mar 12]. Available from: http://ntp.niehs.nih.gov.
-
-
-
-
29
-
-
0016733656
-
N′-nitrosonornicotine in tobacco: Analysis of possible contributing factors and biologic implications
-
Hecht SS, Ornaf RM, Hoffmann D. N′-nitrosonornicotine in tobacco: analysis of possible contributing factors and biologic implications. J Natl Cancer Inst 1974;54:1237-44.
-
(1974)
J Natl Cancer Inst
, vol.54
, pp. 1237-1244
-
-
Hecht, S.S.1
Ornaf, R.M.2
Hoffmann, D.3
-
30
-
-
0003526345
-
-
National Academy of Sciences - National Research Council Academy of Life Sciences. Washington, DC: National Academy Press
-
National Academy of Sciences - National Research Council Academy of Life Sciences. The health effects of nitrate, nitrite and n-nitroso compounds. Washington, DC: National Academy Press, 1981.
-
(1981)
The Health Effects of Nitrate, Nitrite and N-nitroso Compounds
-
-
-
31
-
-
0017803648
-
Reaction of nicotine and sodium nitrite: Formation of nitrosamines and fragmentation of the pyrrolidine ring
-
DOI 10.1021/jo00395a017
-
Hecht SS, Chen CB, Ornaf RM, Jacobs E, Adams JD, Hoffmann D. Reaction of nicotine and sodium nitrite: formation of nitrosamines and fragmentation of the pyrrolidine ring. J Org Chem 1978;43:72-6. (Pubitemid 8335053)
-
(1978)
Journal of Organic Chemistry
, vol.43
, Issue.1
, pp. 72-76
-
-
Hecht, S.S.1
Chen, C.H.B.2
Ornaf, R.M.3
-
32
-
-
77954774837
-
A collaborative study for the determination of tobacco specific nitrosamines in tobacco
-
Morgan WT, Reece JB, Risner CH, Bennett CB, Midgett CH, Johnson KS, et al. A collaborative study for the determination of tobacco specific nitrosamines in tobacco. Beitrage zur Tabakforsch Intl 2004; 21:192-203. (Pubitemid 39499590)
-
(2004)
BEITRAGE ZUR TABAKFORSCHUNG INTERNATIONAL
, vol.21
, Issue.3
, pp. 192-203
-
-
Morgan, W.T.1
Reece, J.B.2
Risner, C.H.3
Bennett, C.B.4
Midgett, C.H.5
Johnson, K.S.6
Burton, H.R.7
-
33
-
-
0141705532
-
Simultaneous determination of five tobacco-specific nitrosamines in mainstream cigarette smoke by isotope dilution liquid chromatography/ electrospray ionization tandem mass spectrometry
-
DOI 10.1021/ac030135y
-
Wu W, Ashley DL, Watson CH. Simultaneous determination of five tobacco-specific nitrosamines in mainstream cigarette smoke by isotope dilution liquid chromatography/electrospray ionization tandem mass spectrometry. Anal Chem 2003;75:4827-32. (Pubitemid 37139784)
-
(2003)
Analytical Chemistry
, vol.75
, Issue.18
, pp. 4827-4832
-
-
Wu, W.1
Ashley, D.L.2
Watson, C.H.3
-
34
-
-
20144369093
-
Tobacco smoke and involuntary smoking
-
International Agency for Research on Cancer. Lyon, FR: IARC
-
International Agency for Research on Cancer. Tobacco smoke and involuntary smoking. In: IARC monographs on the evaluation of carcinogenic risks to humans. Vol. 83. Lyon, FR: IARC; 2004. p. 33-1413.
-
(2004)
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
, vol.83
, pp. 33-1413
-
-
-
35
-
-
26444586762
-
Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from U.S.-brand and non-U.S.-brand cigarettes from 14 countries
-
DOI 10.1080/14622200500125898
-
Wu W, Zhang L, Jain RB, Ashley DL, Watson CH. Determination of carcinogenic tobacco-specific nitrosamines in mainstream smoke from U.S.-brand and non-U.S.-brand cigarettes from 14 countries. Nicotine Tob Res 2005;7:443-51. (Pubitemid 41418717)
-
(2005)
Nicotine and Tobacco Research
, vol.7
, Issue.3
, pp. 443-451
-
-
Wu, W.1
Zhang, L.2
Jain, R.B.3
Ashley, D.L.4
Watson, C.H.5
-
36
-
-
0038142365
-
Tobacco-specific nitrosamines in tobacco from U.S. brand and non-U.S. brand cigarettes
-
DOI 10.1080/14622200307202
-
Ashley DL, Beeson MD, Johnson DR, McCraw JM, Richter P, Pirkle JL, et al. Tobacco-specific nitrosamines in tobacco from U.S. brand and non-U.S. brand cigarettes. Nicotine Tob Res 2003;5:323-31. (Pubitemid 36764027)
-
(2003)
Nicotine and Tobacco Research
, vol.5
, Issue.3
, pp. 323-331
-
-
Ashley, D.L.1
Beeson, M.D.2
Johnson, D.R.3
McCraw, J.M.4
Richter, P.5
Pirkle, J.L.6
Pechacek, T.F.7
Song, S.8
Watson, C.H.9
-
37
-
-
84876784797
-
Determination of tobacco-specific nitrosamines in replacement liquids of electronic cigarettes by liquid chromatographytandem mass spectrometry
-
Kim HJ, Shin HS. Determination of tobacco-specific nitrosamines in replacement liquids of electronic cigarettes by liquid chromatographytandem mass spectrometry. J Chromatogr A 2013;1291:48-55.
-
(2013)
J Chromatogr A
, vol.1291
, pp. 48-55
-
-
Kim, H.J.1
Shin, H.S.2
-
38
-
-
84893908308
-
Levels of selected carcinogens and toxicants in vapour from electronic cigarettes
-
Goniewicz ML, Knysak J, Gawron M, Kosmider L, Sobczak A, Kurek J, et al. Levels of selected carcinogens and toxicants in vapour from electronic cigarettes. Tob Control 2013;23:133-9.
-
(2013)
Tob Control
, vol.23
, pp. 133-139
-
-
Goniewicz, M.L.1
Knysak, J.2
Gawron, M.3
Kosmider, L.4
Sobczak, A.5
Kurek, J.6
-
39
-
-
70350539591
-
Presence of the carcinogen N′-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products
-
Stepanov I, Carmella SG, Briggs A, Hertsgaard L, Lindgren B, Hatsukami DK, et al. Presence of the carcinogen N′-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products. Cancer Res 2009;69:8236-40.
-
(2009)
Cancer Res
, vol.69
, pp. 8236-8240
-
-
Stepanov, I.1
Carmella, S.G.2
Briggs, A.3
Hertsgaard, L.4
Lindgren, B.5
Hatsukami, D.K.6
-
40
-
-
84904293760
-
A comparative study of systemic carcinogen exposure in waterpipe smokers, cigarette smokers and non-smokers
-
Sep 2. [Epub ahead of print]
-
Al Ali R, Rastam S, Ibrahim I, Bazzi A, Fayad S, Shihadeh AL, et al. A comparative study of systemic carcinogen exposure in waterpipe smokers, cigarette smokers and non-smokers. Tob Control 2013 Sep 2. [Epub ahead of print].
-
(2013)
Tob Control
-
-
Al Ali, R.1
Rastam, S.2
Ibrahim, I.3
Bazzi, A.4
Fayad, S.5
Shihadeh, A.L.6
-
41
-
-
84871546022
-
Tobacco-specific nitrosamine exposures in smokers and nonsmokers exposed to cigarette or waterpipe tobacco smoke
-
Radwan G, Hecht SS, Carmella SG, Loffredo CA. Tobacco-specific nitrosamine exposures in smokers and nonsmokers exposed to cigarette or waterpipe tobacco smoke. Nicotine Tob Res 2013;15:130-8.
-
(2013)
Nicotine Tob Res
, vol.15
, pp. 130-138
-
-
Radwan, G.1
Hecht, S.S.2
Carmella, S.G.3
Loffredo, C.A.4
-
42
-
-
84902488467
-
Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers
-
Mar 3. [Epub ahead of print]
-
Kassem NO, Daffa RM, Liles S, Jackson SR, Kassem NO, Younis MA, et al. Children's exposure to secondhand and thirdhand smoke carcinogens and toxicants in homes of hookah smokers. Nicotine Tob Res 2014 Mar 3. [Epub ahead of print]
-
(2014)
Nicotine Tob Res
-
-
Kassem, N.O.1
Daffa, R.M.2
Liles, S.3
Jackson, S.R.4
Kassem, N.O.5
Younis, M.A.6
-
43
-
-
77953298450
-
Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers
-
Ashley DL, O'Connor RJ, Bernert JT, Watson CH, Polzin GM, Jain RB, et al. Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers. Cancer Epidemiol Biomarkers Prev 2010;19:1389-98.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 1389-1398
-
-
Ashley, D.L.1
O'Connor, R.J.2
Bernert, J.T.3
Watson, C.H.4
Polzin, G.M.5
Jain, R.B.6
-
44
-
-
0032842586
-
Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1- butanol enantiomers and metabolites in the A/J mouse
-
DOI 10.1093/carcin/20.8.1577
-
Upadhyaya P, Kenney PMJ, Hochalter JB, Wang M, Hecht SS. Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) enantiomers and metabolites in the A/J mouse. Carcinogenesis 1999;20:1577-82. (Pubitemid 29385448)
-
(1999)
Carcinogenesis
, vol.20
, Issue.8
, pp. 1577-1582
-
-
Upadhyaya, P.1
Kenney, P.M.J.2
Hochalter, J.B.3
Wang, M.4
Hecht, S.S.5
-
45
-
-
84882709238
-
High throughput liquid and gas chromatography-tandem mass spectrometry assays for tobacco-specific nitrosamine and polycyclic aromatic hydrocarbon metabolites associated with lung cancer in smokers
-
Carmella SG, Ming X, Olvera N, Brookmeyer C, Yoder A, Hecht SS. High throughput liquid and gas chromatography-tandem mass spectrometry assays for tobacco-specific nitrosamine and polycyclic aromatic hydrocarbon metabolites associated with lung cancer in smokers. Chem Res Toxicol 2013;26:1209-17.
-
(2013)
Chem Res Toxicol
, vol.26
, pp. 1209-1217
-
-
Carmella, S.G.1
Ming, X.2
Olvera, N.3
Brookmeyer, C.4
Yoder, A.5
Hecht, S.S.6
-
46
-
-
0027522682
-
Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanone in smokers' urine
-
Carmella SG, Akerkar S, Hecht SS. Metabolites of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers' urine. Cancer Res 1993;53:721-4. (Pubitemid 23077849)
-
(1993)
Cancer Research
, vol.53
, Issue.4
, pp. 721-724
-
-
Carmella, S.G.1
Akerkar, S.2
Hecht, S.S.3
-
47
-
-
77949782362
-
A review of the analysis of tobacco-specific nitrosamines in biological matrices
-
Shah KA, Karnes HT. A review of the analysis of tobacco-specific nitrosamines in biological matrices. Crit Rev Toxicol 2010;40:305-27.
-
(2010)
Crit Rev Toxicol
, vol.40
, pp. 305-327
-
-
Shah, K.A.1
Karnes, H.T.2
-
48
-
-
0027380766
-
A tobacco-specific lung carcinogen in the urine of men exposed to cigarette smoke
-
DOI 10.1056/NEJM199311183292105
-
Hecht SS, Carmella SG, Murphy SE, Akerkar S, Brunnemann KD, Hoffmann D. A tobacco-specific lung carcinogen in the urine of men exposed to cigarette smoke. N Engl J Med 1993;329:1543-6. (Pubitemid 23332440)
-
(1993)
New England Journal of Medicine
, vol.329
, Issue.21
, pp. 1543-1546
-
-
Hecht, S.S.1
Carmella, S.G.2
Murphy, S.E.3
Akerkar, S.4
Brunnemann, K.D.5
Hoffmann, D.6
-
49
-
-
0033518904
-
Metabolites of a tobacco-specific carcinogen in urine from newborns
-
Lackmann GM, Salzberger U, Tollner U, Chen M, Carmella SG, Hecht SS. Metabolites of a tobacco-specific carcinogen in the urine of newborns. J Natl Cancer Inst 1999;91:459-65. (Pubitemid 29128283)
-
(1999)
Journal of the National Cancer Institute
, vol.91
, Issue.5
, pp. 459-465
-
-
Lackmann, G.M.1
Salzberger, U.2
Tollner, U.3
Chen, M.4
Carmella, S.G.5
Hecht, S.S.6
-
50
-
-
0036313209
-
Human urinary carcinogen metabolites: Biomarkers for investigating tobacco and cancer
-
Hecht SS. Human urinary carcinogen metabolites: biomarkers for investigating tobacco and cancer. Carcinogenesis 2002;23:907-22. (Pubitemid 34752946)
-
(2002)
Carcinogenesis
, vol.23
, Issue.6
, pp. 907-922
-
-
Hecht, S.S.1
-
51
-
-
0034083584
-
A tobacco-specific carcinogen in the fetus
-
DOI 10.1002/(SICI)1097-0223(200004)20:4<307::AID-P
-
Milunsky A, Carmella SG, Ye M, Hecht SS. A tobacco-specific carcinogen in the fetus. Prenat Diagn 2000;20:307-10. (Pubitemid 30204163)
-
(2000)
Prenatal Diagnosis
, vol.20
, Issue.4
, pp. 307-310
-
-
Milunsky, A.1
Carmella, S.G.2
Ye, M.3
Hecht, S.S.4
-
52
-
-
79957880610
-
Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking
-
Goniewicz ML, Eisner MD, Lazcano-Ponce E, Zielinska-Danch W, Koszowski B, Sobczak A, et al. Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking. Nicotine Tob Res 2011;13:202-8.
-
(2011)
Nicotine Tob Res
, vol.13
, pp. 202-208
-
-
Goniewicz, M.L.1
Eisner, M.D.2
Lazcano-Ponce, E.3
Zielinska-Danch, W.4
Koszowski, B.5
Sobczak, A.6
-
53
-
-
78549278152
-
Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U. S. population from secondhand smoke exposure
-
Bernert JT, Pirkle JL, Xia Y, Jain RB, Ashley DL, Sampson EJ. Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U. S. population from secondhand smoke exposure. Cancer Epidemiol Biomarkers Prev 2010;19:2969-77.
-
(2010)
Cancer Epidemiol Biomarkers Prev
, vol.19
, pp. 2969-2977
-
-
Bernert, J.T.1
Pirkle, J.L.2
Xia, Y.3
Jain, R.B.4
Ashley, D.L.5
Sampson, E.J.6
-
54
-
-
79958043216
-
Metabolites of a tobacco-specific lung carcinogen in children exposed to secondhand or thirdhand tobacco smoke in their homes
-
Thomas JL, Guo H, Carmella SG, Balbo S, Han S, Davis A, et al. Metabolites of a tobacco-specific lung carcinogen in children exposed to secondhand or thirdhand tobacco smoke in their homes. Cancer Epidemiol Biomarkers Prev 2011;20:1213-21.
-
(2011)
Cancer Epidemiol Biomarkers Prev
, vol.20
, pp. 1213-1221
-
-
Thomas, J.L.1
Guo, H.2
Carmella, S.G.3
Balbo, S.4
Han, S.5
Davis, A.6
-
55
-
-
80052426180
-
Urinary levels of the tobacco-speci fic carcinogen N′- nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers
-
Yuan JM, Knezevich AD, Wang R, Gao YT, Hecht SS, Stepanov I. Urinary levels of the tobacco-speci fic carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers. Carcinogenesis 2011;32:1366-71.
-
(2011)
Carcinogenesis
, vol.32
, pp. 1366-1371
-
-
Yuan, J.M.1
Knezevich, A.D.2
Wang, R.3
Gao, Y.T.4
Hecht, S.S.5
Stepanov, I.6
-
56
-
-
16444374852
-
Tobacco-specific nitrosamines and their pyridine-N-glucuronides in the urine of smokers and smokeless tobacco users
-
DOI 10.1158/1055-9965.EPI-04-0753
-
Stepanov I, Hecht SS. Tobacco-specific nitrosamines and their N-glucuronides in the urine of smokers and smokeless tobacco users. Cancer Epidemiol Biomarkers Prev 2005;14:885-91. (Pubitemid 40478552)
-
(2005)
Cancer Epidemiology Biomarkers and Prevention
, vol.14
, Issue.4
, pp. 885-891
-
-
Stepanov, I.1
Hecht, S.S.2
-
57
-
-
72949106216
-
Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers
-
Kavvadias D, Scherer G, Cheung F, Errington G, Shepperd J, McEwan M. Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers. Biomarkers 2009;14:547-53.
-
(2009)
Biomarkers
, vol.14
, pp. 547-553
-
-
Kavvadias, D.1
Scherer, G.2
Cheung, F.3
Errington, G.4
Shepperd, J.5
McEwan, M.6
-
58
-
-
68949096343
-
Quantitation of N′-nitrosonornicotine (NNN) in smokers' urine by liquid chromatography-tandem mass spectrometry
-
Urban M, Scherer G, Kavvadias D, Hagedorn HW, Feng S, Serafin R, et al. Quantitation of N′-nitrosonornicotine (NNN) in smokers' urine by liquid chromatography-tandem mass spectrometry. J Anal Toxicol 2009;33:260-5.
-
(2009)
J Anal Toxicol
, vol.33
, pp. 260-265
-
-
Urban, M.1
Scherer, G.2
Kavvadias, D.3
Hagedorn, H.W.4
Feng, S.5
Serafin, R.6
-
59
-
-
84893728081
-
Quantitative analysis of five tobacco-specific N-nitrosamines in urine by liquid chromatography-atmospheric pressure ionization tandem mass spectrometry
-
Oct 11. [Epub ahead of print]
-
Xia B, Xia Y, Wong J, Nicodemus KJ, Xu M, Lee J, et al. Quantitative analysis of five tobacco-specific N-nitrosamines in urine by liquid chromatography-atmospheric pressure ionization tandem mass spectrometry. Biomed Chromatogr 2013 Oct 11. [Epub ahead of print].
-
(2013)
Biomed Chromatogr
-
-
Xia, B.1
Xia, Y.2
Wong, J.3
Nicodemus, K.J.4
Xu, M.5
Lee, J.6
-
61
-
-
78751574026
-
Do changes in cigarette design influence the rise in adenocarcinoma of the lung?
-
Burns DM, Anderson CM, Gray N. Do changes in cigarette design influence the rise in adenocarcinoma of the lung? Cancer Causes Control 2011;22:13-22.
-
(2011)
Cancer Causes Control
, vol.22
, pp. 13-22
-
-
Burns, D.M.1
Anderson, C.M.2
Gray, N.3
-
62
-
-
0027488025
-
Cigarette smoking and adenocarcinoma of the lung: The relevance of nicotine-derived N-nitrosamines
-
Hoffmann D, Rivenson A, Murphy SE, Chung FL, Amin S, Hecht SS. Cigarette smoking and adenocarcinoma of the lung: the relevance of nicotine-derivedN- nitrosamines. JSmokingRelatDisord1993;4:165-89. (Pubitemid 23344039)
-
(1993)
Journal of Smoking-Related Disorders
, vol.4
, Issue.3
, pp. 165-189
-
-
Hoffmann, D.1
Rivenson, A.2
Murphy, S.E.3
Chung, F.-L.4
Amin, S.5
Hecht, S.S.6
-
63
-
-
84877254889
-
Smoking-related mortality in the United States
-
Thun MJ, Lopez AD, Hartge P. Smoking-related mortality in the United States. N Engl J Med 2013;368:1753.
-
(2013)
N Engl J Med
, vol.368
, pp. 1753
-
-
Thun, M.J.1
Lopez, A.D.2
Hartge, P.3
-
65
-
-
1642284144
-
Mainstream smoke constituent yields and predicting relationships from a worldwide market sample of cigarette brands: ISO smoking conditions
-
DOI 10.1016/j.yrtph.2003.12.005, PII S027323000300148X
-
Counts ME, Hsu FS, Laffoon SW, Dwyer RW, Cox RH. Mainstream smoke constituent yields and predicting relationships from a worldwide market sample of cigarette brands: ISO smoking conditions. Regul Toxicol Pharmacol 2004;39:111-34. (Pubitemid 38388196)
-
(2004)
Regulatory Toxicology and Pharmacology
, vol.39
, Issue.2
, pp. 111-134
-
-
Counts, M.E.1
Hsu, F.S.2
Laffoon, S.W.3
Dwyer, R.W.4
Cox, R.H.5
-
66
-
-
78649298689
-
Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures
-
International Agency for Research on Cancer. Lyon, FR: IARC
-
International Agency for Research on Cancer. Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures. In: IARC monographs on the evaluation of carcinogenic risks to humans, vol. 92. Lyon, FR: IARC; 2010. p. 35-818.
-
(2010)
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
, vol.92
, pp. 35-818
-
-
-
67
-
-
58449110294
-
A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers
-
Church TR, Anderson KE, Caporaso NE, Geisser MS, Le C, Zhang Y, et al. A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers. Cancer Epidemiol Biomarkers Prev 2009;18:260-6.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 260-266
-
-
Church, T.R.1
Anderson, K.E.2
Caporaso, N.E.3
Geisser, M.S.4
Le, C.5
Zhang, Y.6
-
68
-
-
66149145341
-
Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers
-
Yuan JM, Koh WP, Murphy SE, Fan Y, Wang R, Carmella SG, et al. Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers. Cancer Res 2009;69:2990-5.
-
(2009)
Cancer Res
, vol.69
, pp. 2990-2995
-
-
Yuan, J.M.1
Koh, W.P.2
Murphy, S.E.3
Fan, Y.4
Wang, R.5
Carmella, S.G.6
-
69
-
-
80355139536
-
Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers
-
Yuan J-M, Gao Y-T, Murphy SE, Carmella SG, Wang R, Zhong Y, et al. Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers. Cancer Res 2011;71:6749-57.
-
(2011)
Cancer Res
, vol.71
, pp. 6749-6757
-
-
Yuan, J.-M.1
Gao, Y.-T.2
Murphy, S.E.3
Carmella, S.G.4
Wang, R.5
Zhong, Y.6
-
70
-
-
84892947651
-
Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer
-
Yuan JM, Butler LM, Stepanov I, Hecht SS. Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer. Cancer Res 2014;74:401-11.
-
(2014)
Cancer Res
, vol.74
, pp. 401-411
-
-
Yuan, J.M.1
Butler, L.M.2
Stepanov, I.3
Hecht, S.S.4
-
71
-
-
84891919590
-
Tobacco smoke biomarkers and cancer risk among male smokers in the Shanghai Cohort Study
-
Hecht SS, Murphy SE, Stepanov I, Nelson HH, Yuan J-M. Tobacco smoke biomarkers and cancer risk among male smokers in the Shanghai Cohort Study. Cancer Lett 2012;334:34-8.
-
(2012)
Cancer Lett
, vol.334
, pp. 34-38
-
-
Hecht, S.S.1
Murphy, S.E.2
Stepanov, I.3
Nelson, H.H.4
Yuan, J.-M.5
-
72
-
-
84895922218
-
Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: Remarkable coherence with rat tumor sites
-
Stepanov I, Sebero E, Wang R, Gao YT, Hecht SS, Yuan JM. Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: remarkable coherence with rat tumor sites. Int J Cancer 2014;134:2278-83.
-
(2014)
Int J Cancer
, vol.134
, pp. 2278-2283
-
-
Stepanov, I.1
Sebero, E.2
Wang, R.3
Gao, Y.T.4
Hecht, S.S.5
Yuan, J.M.6
-
73
-
-
31344479326
-
Ethnic and racial differences in the smoking-related risk of lung cancer
-
DOI 10.1056/NEJMoa033250
-
Haiman CA, Stram DO, Wilkens LR, Pike MC, Kolonel LN, Henderson BE, et al. Ethnic and racial differences in the smoking-related risk of lung cancer. N Engl J Med 2006;354:333-42. (Pubitemid 43145058)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.4
, pp. 333-342
-
-
Haiman, C.A.1
Stram, D.O.2
Wilkens, L.R.3
Pike, M.C.4
Kolonel, L.N.5
Henderson, B.E.6
Marchand, L.L.7
-
74
-
-
42149192001
-
Mandated lowering of toxicants in cigarette smoke: A description of the World Health Organization TobReg proposal
-
Burns DM, Dybing E, Gray N, Hecht S, Anderson C, Sanner T, et al. Mandated lowering of toxicants in cigarette smoke: a description of the World Health Organization TobReg proposal. Tob Control 2008; 17:132-41.
-
(2008)
Tob Control
, vol.17
, pp. 132-141
-
-
Burns, D.M.1
Dybing, E.2
Gray, N.3
Hecht, S.4
Anderson, C.5
Sanner, T.6
-
75
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
76
-
-
84892759866
-
Current cigarette smoking among adults - United States, 2005-2012
-
Agaku IT, King BA, Dube SR. Current cigarette smoking among adults - United States, 2005-2012. MMWR Morb Mortal Wkly Rep 2014;63:29-34.
-
(2014)
MMWR Morb Mortal Wkly Rep
, vol.63
, pp. 29-34
-
-
Agaku, I.T.1
King, B.A.2
Dube, S.R.3
-
77
-
-
84876709598
-
Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list
-
U. S. Food and Drug Administration
-
U. S. Food and Drug Administration. Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list. Fed Regist 2012;77:20034-7.
-
(2012)
Fed Regist
, vol.77
, pp. 20034-20037
-
-
-
78
-
-
0003989598
-
-
Institute of Medicine, Washington, DC: National Academy Press
-
Stratton K, Shetty P, Wallace R, Bondurant S. Clearing the smoke: assessing the science base for tobacco harm reduction. Institute of Medicine, Washington, DC: National Academy Press; 2001.
-
(2001)
Clearing the Smoke: Assessing the Science Base for Tobacco Harm Reduction
-
-
Stratton, K.1
Shetty, P.2
Wallace, R.3
Bondurant, S.4
-
80
-
-
73349135619
-
-
CEBP Focus: Tobacco Research
-
CEBP Focus: Tobacco Research. Cancer Epidemiol Biomarkers Prev 2009;18:3139-348.
-
(2009)
Cancer Epidemiol Biomarkers Prev
, vol.18
, pp. 3139-3348
-
-
-
81
-
-
84855170277
-
Research opportunities to inform tobacco product regulation in the United States
-
Leischow S, Zeller M. Research opportunities to inform tobacco product regulation in the United States. Nicotine Tob Res 2012;14:1-74.
-
(2012)
Nicotine Tob Res
, vol.14
, pp. 1-74
-
-
Leischow, S.1
Zeller, M.2
-
82
-
-
57449088841
-
Levels of tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons in mainstream smoke from different tobacco varieties
-
Ding YS, Zhang L, Jain RB, Jain N, Wang RY, Ashley DL, et al. Levels of tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons in mainstream smoke from different tobacco varieties. Cancer Epidemiol Biomarkers Prev 2008;17:3366-71.
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 3366-3371
-
-
Ding, Y.S.1
Zhang, L.2
Jain, R.B.3
Jain, N.4
Wang, R.Y.5
Ashley, D.L.6
-
83
-
-
84855169062
-
Postmarketing surveillance for "modified-risk" tobacco products
-
O'Connor RJ. Postmarketing surveillance for "modified-risk" tobacco products. Nicotine Tob Res 2012;14:29-42.
-
(2012)
Nicotine Tob Res
, vol.14
, pp. 29-42
-
-
O'Connor, R.J.1
-
84
-
-
0011365442
-
Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine
-
National Cancer Institute. Bethesda, MD: U.S. Dept of Health and Human Services, National Institutes of Health, National Cancer Institute, NIH Pub. No. 99-4645
-
National Cancer Institute. Risks associated with smoking cigarettes with low machine-measured yields of tar and nicotine. Smoking and tobacco control monograph no. 13. Bethesda, MD: U.S. Dept of Health and Human Services, National Institutes of Health, National Cancer Institute, NIH Pub. No. 99-4645; 2001.
-
(2001)
Smoking and Tobacco Control Monograph No. 13
-
-
|