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Volumn 307, Issue 2, 2014, Pages

Extranuclear estrogen receptor's roles in physiology: Lessons from mouse models

Author keywords

Membrane estrogen receptor; Signal transduction; Steroid receptors

Indexed keywords

MEMBRANE ESTROGEN RECEPTOR; SIGNAL TRANSDUCTION; STEROID RECEPTORS;

EID: 84904284909     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00626.2013     Document Type: Review
Times cited : (54)

References (66)
  • 3
    • 33847755409 scopus 로고    scopus 로고
    • G proteincoupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L, Madeo A, Lappano R, Vivacqua A, Rago V, Carpino A, Oprea TI, Prossnitz ER, Musti AM, Andò S, Maggiolini M. G proteincoupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 67: 1859-1866, 2007.
    • (2007) Cancer Res , vol.67 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6    Oprea, T.I.7    Prossnitz, E.R.8    Musti, A.M.9    Andò, S.10    Maggiolini, M.11
  • 5
    • 84861411190 scopus 로고    scopus 로고
    • Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex
    • Bhatt S, Xiao Z, Meng Z, Katzenellenbogen BS. Phosphorylation by p38 mitogen-activated protein kinase promotes estrogen receptor α turnover and functional activity via the SCF(Skp2) proteasomal complex. Mol Cell Biol 32: 1928-1943, 2012.
    • (2012) Mol Cell Biol , vol.32 , pp. 1928-1943
    • Bhatt, S.1    Xiao, Z.2    Meng, Z.3    Katzenellenbogen, B.S.4
  • 7
    • 15444368857 scopus 로고    scopus 로고
    • Mechanisms of estrogen receptor signaling: Convergence of genomic and nongenomic actions on target genes
    • Björnström L, Sjöberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes. Mol Endocrinol 19: 833-842, 2005.
    • (2005) Mol Endocrinol , vol.19 , pp. 833-842
    • Björnström, L.1    Sjöberg, M.2
  • 10
    • 0025081214 scopus 로고
    • Transcription factor interactions: Selectors of positive or negative regulation from a single DNA element
    • Diamond MI, Miner JN, Yoshinaga SK, Yamamoto KR. Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science 249: 1266-1272, 1990.
    • (1990) Science , vol.249 , pp. 1266-1272
    • Diamond, M.I.1    Miner, J.N.2    Yoshinaga, S.K.3    Yamamoto, K.R.4
  • 11
    • 77950354885 scopus 로고    scopus 로고
    • Insulinsensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression
    • Fierz Y, Novosyadlyy R, Vijayakumar A, Yakar S, LeRoith D. Insulinsensitizing therapy attenuates type 2 diabetes-mediated mammary tumor progression. Diabetes 59: 686-693, 2010.
    • (2010) Diabetes , vol.59 , pp. 686-693
    • Fierz, Y.1    Novosyadlyy, R.2    Vijayakumar, A.3    Yakar, S.4    LeRoith, D.5
  • 12
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, gpr30, and occurs via transactivation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo EJ, Quinn JA, Bland KI, Frackelton AR. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, gpr30, and occurs via transactivation of the epidermal growth factor receptor through release of HB-EGF. Mol Endocrinol 14: 1649-1660, 2000.
    • (2000) Mol Endocrinol , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton, A.R.4
  • 13
    • 0031785733 scopus 로고    scopus 로고
    • Differentially expressed messenger RNA isoforms of the human estrogen receptor-alpha gene are generated by alternative splicing and promoter usage
    • Flouriot G, Griffin C, Kennealy MR, Sonntag-Buck V, Gannon F. Differentially expressed messenger RNA isoforms of the human estrogen receptor-alpha gene are generated by alternative splicing and promoter usage. Mol Endocrinol 12: 1939-1954, 1998.
    • (1998) Mol Endocrinol , vol.12 , pp. 1939-1954
    • Flouriot, G.1    Griffin, C.2    Kennealy, M.R.3    Sonntag-Buck, V.4    Gannon, F.5
  • 14
    • 42549141260 scopus 로고    scopus 로고
    • The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation
    • Galluzzo P, Ascenzi P, Bulzomi P, Marino M. The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation. Endocrinology 149: 2567-2575, 2008.
    • (2008) Endocrinology , vol.149 , pp. 2567-2575
    • Galluzzo, P.1    Ascenzi, P.2    Bulzomi, P.3    Marino, M.4
  • 15
    • 37349081370 scopus 로고    scopus 로고
    • Extranuclear steroid receptors: Nature and actions
    • Hammes SR, Levin ER. Extranuclear steroid receptors: nature and actions. Endocr Rev 28: 726-741, 2007.
    • (2007) Endocr Rev , vol.28 , pp. 726-741
    • Hammes, S.R.1    Levin, E.R.2
  • 21
    • 79952179448 scopus 로고    scopus 로고
    • Minireview: Extranuclear steroid receptors: Roles in modulation of cell functions
    • Levin ER. Minireview: Extranuclear steroid receptors: roles in modulation of cell functions. Mol Endocrinol 25: 377-384, 2011.
    • (2011) Mol Endocrinol , vol.25 , pp. 377-384
    • Levin, E.R.1
  • 22
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells
    • Li L, Haynes MP, Bender JR. Plasma membrane localization and function of the estrogen receptor alpha variant (ER46) in human endothelial cells. Proc Natl Acad Sci USA 100: 4807-4812, 2003.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4807-4812
    • Li, L.1    Haynes, M.P.2    Bender, J.R.3
  • 23
    • 0037224484 scopus 로고    scopus 로고
    • Nongenomic actions of steroid hormones
    • Losel R, Wehling M. Nongenomic actions of steroid hormones. Nat Rev Mol Cell Biol 4: 46-56, 2003.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 46-56
    • Losel, R.1    Wehling, M.2
  • 25
    • 84878632677 scopus 로고    scopus 로고
    • The role of estrogens in control of energy balance and glucose homeostasis
    • Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev 34: 309-338, 2013.
    • (2013) Endocr Rev , vol.34 , pp. 309-338
    • Mauvais-Jarvis, F.1    Clegg, D.J.2    Hevener, A.L.3
  • 27
    • 84863318702 scopus 로고    scopus 로고
    • Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension
    • Nadadur RD, Umar S, Wong G, Eghbali M. Reverse right ventricular structural and extracellular matrix remodeling by estrogen in severe pulmonary hypertension. J Appl Physiol 113: 149-158, 2012.
    • (2012) J Appl Physiol , vol.113 , pp. 149-158
    • Nadadur, R.D.1    Umar, S.2    Wong, G.3    Eghbali, M.4
  • 29
    • 0033304691 scopus 로고    scopus 로고
    • Estrogen receptor-alpha detected on the plasma membrane of aldehyde-fixed GH3/B6/ F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry
    • Norfleet AM, Thomas ML, Gametchu B, Watson CS. Estrogen receptor-alpha detected on the plasma membrane of aldehyde-fixed GH3/B6/ F10 rat pituitary tumor cells by enzyme-linked immunocytochemistry. Endocrinology 140: 3805-3814, 1999.
    • (1999) Endocrinology , vol.140 , pp. 3805-3814
    • Norfleet, A.M.1    Thomas, M.L.2    Gametchu, B.3    Watson, C.S.4
  • 31
    • 84870360401 scopus 로고    scopus 로고
    • Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells
    • O'Mahony F, Pedram A, Razandi M, Harvey BH, Levin ER. Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells. Mol Endocrinol 26: 2058-2070, 2012.
    • (2012) Mol Endocrinol , vol.26 , pp. 2058-2070
    • O'Mahony, F.1    Pedram, A.2    Razandi, M.3    Harvey, B.H.4    Levin, E.R.5
  • 34
    • 0028925081 scopus 로고
    • Membrane estrogen receptors identified by multiple antibody labeling and impeded ligand binding
    • Pappas TC, Gametchu B, Yannariello-Brown J, Collins TJ, Watson CS. Membrane estrogen receptors identified by multiple antibody labeling and impeded ligand binding. FASEB J 9: 404-410, 1995.
    • (1995) FASEB J , vol.9 , pp. 404-410
    • Pappas, T.C.1    Gametchu, B.2    Yannariello-Brown, J.3    Collins, T.J.4    Watson, C.S.5
  • 36
  • 37
    • 33747841976 scopus 로고    scopus 로고
    • Nature of functional estrogen receptors at the plasma membrane
    • Pedram A, Razandi M, Levin ER. Nature of functional estrogen receptors at the plasma membrane. Mol Endocrinol 20: 1996-2009, 2006.
    • (2006) Mol Endocrinol , vol.20 , pp. 1996-2009
    • Pedram, A.1    Razandi, M.2    Levin, E.R.3
  • 38
    • 0037184912 scopus 로고    scopus 로고
    • Integration of the non-genomic and genomic actions of estrogen. Membraneinitiated signaling by steroid to transcription and cell biology
    • Pedram A, Razandi M, Aitkenhead M, Hughes CC, Levin ER. Integration of the non-genomic and genomic actions of estrogen. Membraneinitiated signaling by steroid to transcription and cell biology. J Biol Chem 277: 50768-50775, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 50768-50775
    • Pedram, A.1    Razandi, M.2    Aitkenhead, M.3    Hughes, C.C.4    Levin, E.R.5
  • 39
    • 34547928773 scopus 로고    scopus 로고
    • A conserved mechanism for steroid receptor translocation to the plasma membrane
    • Pedram A, Razandi M, Sainson RC, Kim JK, Hughes CC, Levin ER. A conserved mechanism for steroid receptor translocation to the plasma membrane. J Biol Chem 282: 22278-22288, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 22278-22288
    • Pedram, A.1    Razandi, M.2    Sainson, R.C.3    Kim, J.K.4    Hughes, C.C.5    Levin, E.R.6
  • 40
    • 84855398593 scopus 로고    scopus 로고
    • DHHC-7 and-21 are palmitoylacyltransferases for sex steroid receptors
    • Pedram A, Razandi M, Deschenes R, Levin ER. DHHC-7 and-21 are palmitoylacyltransferases for sex steroid receptors. Mol Biol Cell 23: 188-199, 2012.
    • (2012) Mol Biol Cell , vol.23 , pp. 188-199
    • Pedram, A.1    Razandi, M.2    Deschenes, R.3    Levin, E.R.4
  • 41
    • 46349084173 scopus 로고    scopus 로고
    • Estrogen inhibits cardiac hypertrophy: Role of estrogen receptor-beta to inhibit calcineurin
    • Pedram A, Razandi M, Lubahn D, Liu J, Vannan M, Levin ER. Estrogen inhibits cardiac hypertrophy: role of estrogen receptor-beta to inhibit calcineurin. Endocrinology 149: 3361-3369, 2008.
    • (2008) Endocrinology , vol.149 , pp. 3361-3369
    • Pedram, A.1    Razandi, M.2    Lubahn, D.3    Liu, J.4    Vannan, M.5    Levin, E.R.6
  • 42
    • 84886482116 scopus 로고    scopus 로고
    • ERβ selective agonist inhibits angiotensin-induced cardiovascular pathology in female mice
    • Pedram A, Razandi M, Korach K, Narayanan R, Dalton J, Levin ER. ERβ selective agonist inhibits angiotensin-induced cardiovascular pathology in female mice. Endocrinology 154: 4352-4364, 2013.
    • (2013) Endocrinology , vol.154 , pp. 4352-4364
    • Pedram, A.1    Razandi, M.2    Korach, K.3    Narayanan, R.4    Dalton, J.5    Levin, E.R.6
  • 43
    • 22544488420 scopus 로고    scopus 로고
    • Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1
    • Pedram A, Razandi R, Aitkenhead M, Levin ER. Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1. J Biol Chem 280: 26339-26348, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 26339-26348
    • Pedram, A.1    Razandi, R.2    Aitkenhead, M.3    Levin, E.R.4
  • 46
    • 84901412371 scopus 로고    scopus 로고
    • Membrane-Localized Estrogen Receptor α Is Required for Normal Organ Development and Function
    • Pedram A, Razandi M, Lewis M, Hammes S, Levin ER. Membrane-Localized Estrogen Receptor α Is Required for Normal Organ Development and Function. Dev Cell 29: 482-490, 2014.
    • (2014) Dev Cell , vol.29 , pp. 482-490
    • Pedram, A.1    Razandi, M.2    Lewis, M.3    Hammes, S.4    Levin, E.R.5
  • 47
    • 18144381249 scopus 로고    scopus 로고
    • Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells
    • Pietras RJ, Márquez DC, Chen HW, Tsai E, Weinberg O, Fishbein M. Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells. Steroids 70: 372-381, 2005.
    • (2005) Steroids , vol.70 , pp. 372-381
    • Pietras, R.J.1    Márquez, D.C.2    Chen, H.W.3    Tsai, E.4    Weinberg, O.5    Fishbein, M.6
  • 48
    • 0016436966 scopus 로고
    • Endometrial cell calcium and oestrogen action
    • Pietras RJ, Szego CM. Endometrial cell calcium and oestrogen action. Nature 253: 357-359, 1975.
    • (1975) Nature , vol.253 , pp. 357-359
    • Pietras, R.J.1    Szego, C.M.2
  • 49
    • 0017354142 scopus 로고
    • Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells
    • Pietras RJ, Szego CM. Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature 265: 69-72, 1977.
    • (1977) Nature , vol.265 , pp. 69-72
    • Pietras, R.J.1    Szego, C.M.2
  • 50
    • 77953460074 scopus 로고    scopus 로고
    • Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane
    • Razandi M, Pedram A, Levin ER. Heat shock protein 27 is required for sex steroid receptor trafficking to and functioning at the plasma membrane. Mol Cell Biol 30: 3249-3261, 2010.
    • (2010) Mol Cell Biol , vol.30 , pp. 3249-3261
    • Razandi, M.1    Pedram, A.2    Levin, E.R.3
  • 52
    • 0036139164 scopus 로고    scopus 로고
    • ERs associate with and regulate the production of caveolin: Implications for signaling and cellular actions
    • Razandi M, Oh P, Pedram A, Schnitzer J, Levin ER. ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions. Mol Endocrinol 16: 100-115, 2002.
    • (2002) Mol Endocrinol , vol.16 , pp. 100-115
    • Razandi, M.1    Oh, P.2    Pedram, A.3    Schnitzer, J.4    Levin, E.R.5
  • 53
    • 0037462733 scopus 로고    scopus 로고
    • Proximal events in ER signaling from the plasma membrane
    • Razandi M, Pedram A, Parks S, Levin ER. Proximal events in ER signaling from the plasma membrane. J Biol Chem 278: 2701-2712, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 2701-2712
    • Razandi, M.1    Pedram, A.2    Parks, S.3    Levin, E.R.4
  • 54
    • 0001548401 scopus 로고    scopus 로고
    • Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: Studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells
    • Razandi M, Pedram A, Greene GL, Levin ER. Cell membrane and nuclear estrogen receptors (ERs) originate from a single transcript: studies of ERalpha and ERbeta expressed in Chinese hamster ovary cells. Mol Endocrinol 13: 307-319, 1999.
    • (1999) Mol Endocrinol , vol.13 , pp. 307-319
    • Razandi, M.1    Pedram, A.2    Greene, G.L.3    Levin, E.R.4
  • 55
    • 0037351881 scopus 로고    scopus 로고
    • Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling
    • Reid G, Hubner MR, Metvier R, Brand H, Denger S, Manu D, Beaudouin J, Ellenberg J, Gannon F. Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling. Mol Cell 11: 695-707, 2003.
    • (2003) Mol Cell , vol.11 , pp. 695-707
    • Reid, G.1    Hubner, M.R.2    Metvier, R.3    Brand, H.4    Denger, S.5    Manu, D.6    Beaudouin, J.7    Ellenberg, J.8    Gannon, F.9
  • 56
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307: 1625-1630, 2005.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 57
    • 78049352549 scopus 로고    scopus 로고
    • Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP
    • Sanchez AM, Flamini MI, Baldacci C, Goglia L, Genazzani AR, Simoncini T. Estrogen receptor-alpha promotes breast cancer cell motility and invasion via focal adhesion kinase and N-WASP. Mol Endocrinol 24: 2114-2125, 2010.
    • (2010) Mol Endocrinol , vol.24 , pp. 2114-2125
    • Sanchez, A.M.1    Flamini, M.I.2    Baldacci, C.3    Goglia, L.4    Genazzani, A.R.5    Simoncini, T.6
  • 58
    • 0000221213 scopus 로고
    • Stress and the general adaptation syndrome
    • Selye H. Stress and the general adaptation syndrome. Br J Med 1: 1383-1392, 1950.
    • (1950) Br J Med , vol.1 , pp. 1383-1392
    • Selye, H.1
  • 59
    • 0014140501 scopus 로고
    • Adenosine 3',5'-monophosphate in rat uterus: Acute elevation by estrogen
    • Szego CM, Davis JS. Adenosine 3',5'-monophosphate in rat uterus: acute elevation by estrogen. Proc Natl Acad Sci USA 58: 1711-1718, 1967.
    • (1967) Proc Natl Acad Sci USA , vol.58 , pp. 1711-1718
    • Szego, C.M.1    Davis, J.S.2
  • 61
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P, Pang Y, Filardo EJ, Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146: 624-632, 2005.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 62
    • 84881027754 scopus 로고    scopus 로고
    • Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation
    • Ueda K, Lu Q, Baur W, Aronovitz MJ, Karas RH. Rapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation. Arterioscler Thromb Vasc Biol 33: 1837-1843, 2013.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1837-1843
    • Ueda, K.1    Lu, Q.2    Baur, W.3    Aronovitz, M.J.4    Karas, R.H.5
  • 63
    • 33745160700 scopus 로고    scopus 로고
    • A variant of estrogen receptor-{alpha}, hER-{alpha}36: Transduction of estrogenand antiestrogen-dependent membrane-initiated mitogenic signaling
    • Wang Z, Zhang X, Shen P, Loggie BW, Chang Y, Deuel TF. A variant of estrogen receptor-{alpha}, hER-{alpha}36: transduction of estrogenand antiestrogen-dependent membrane-initiated mitogenic signaling. Proc Natl Acad Sci USA 103: 9063-9068, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 9063-9068
    • Wang, Z.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 64
    • 0035869056 scopus 로고    scopus 로고
    • BRI1 is a critical component of a plasma-membrane receptor for plant steroids
    • Wang ZY, Seto H, Fujioka S, Yoshida S, Chory J. BRI1 is a critical component of a plasma-membrane receptor for plant steroids. Nature 410: 380-383, 2001.
    • (2001) Nature , vol.410 , pp. 380-383
    • Wang, Z.Y.1    Seto, H.2    Fujioka, S.3    Yoshida, S.4    Chory, J.5


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