Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 24, 2010, Pages 11122-11127

  York, Brian ^a   Yu, Chundong ^a,b   Sagen, Jørn V ^a,c,d   Liu, Zhaoliang ^a,e   Nikolai, Bryan C ^a   Wu, Ray Chang ^a   Finegold, Milton ^a   Xu, Jianming ^a   O'Malley, Bert W ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b XIAMEN UNIVERSITY   (China)

^c UNIVERSITY OF BERGEN   (Norway)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^e UNIVERSITY OF TEXAS   (United States)

Author keywords

Coactivator; Metabolism; Obesity; Posttranslational modification

Indexed keywords

ALANINE; SOMATOMEDIN C; STEROID RECEPTOR COACTIVATOR 3;

ANIMAL EXPERIMENT; ARTICLE; BIOLOGY; CARCINOGENESIS; CELL GROWTH; CELL METABOLISM; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; IN VITRO STUDY; IN VIVO STUDY; INSULIN SENSITIVITY; LIVER TUMOR; MAMMAL; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; OBESITY; PHENOTYPE; PHYSIOLOGY; POINT MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; WEIGHT GAIN;

ADIPOSITY; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BODY COMPOSITION; BODY WEIGHT; GENE KNOCK-IN TECHNIQUES; HUMANS; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MAMMALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; NUCLEAR RECEPTOR COACTIVATOR 3; PHENOTYPE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; SYSTEMS BIOLOGY;

MAMMALIA; MUS;

EID: 77954648696     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1005262107     Document Type: Article

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