Surface engineered nanostructured lipid carriers for efficient nose to brain delivery of ondansetron HCl using Delonix regia gum as a natural mucoadhesive polymer

Colloids and Surfaces B: Biointerfaces

Volumn 122, Issue , 2014, Pages 143-150

  Devkar, Tejas B ^a   Tekade, Avinash R ^a   Khandelwal, Kishanchandra R ^a  

^a Rajarshi Shahu College of Pharmacy and Research   (India)

Author keywords

Delonix regia gum; Mucoadhesion; Nanostructured lipid carrier; Nose to brain delivery; Ondansetron HCl; Surface modification

Indexed keywords

COLLOIDS; SURFACE TREATMENT; SURFACES;

BRAIN DELIVERY; DELONIX REGIA GUM; MUCOADHESION; NANOSTRUCTURED LIPID CARRIERS; ONDANSETRON HCL;

PARTICLE SIZE; SURFACE TREATMENT;

DRUG CARRIER; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; ONDANSETRON; PHOSPHATIDYLCHOLINE; PLANT GUM; POLOXAMER; UNCLASSIFIED DRUG; GLYCEROL STEARATE; POLYMER; LIPID; NANOMATERIAL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; BRAIN; CHEMICAL STRUCTURE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DELONIX REGIA; DISPERSION; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TARGETING; DRUG TRANSPORT; FABALES; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; NOSE; NOSE CAVITY; PARTICLE SIZE; PLANT SEED; PRIORITY JOURNAL; RAT; SHEEP; SUSTAINED DRUG RELEASE; THERMODYNAMICS; THERMOSTABILITY; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL; DRUG DISTRIBUTION; EX VIVO STUDY; FABACEAE; HISTOPATHOLOGY; IN VITRO STUDY; NANOFABRICATION; NOSE MUCOSA; ANIMAL; BLOOD BRAIN BARRIER; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; INTRANASAL DRUG ADMINISTRATION; METABOLISM; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TISSUE DISTRIBUTION; X RAY DIFFRACTION;

ADMINISTRATION, INTRANASAL; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CALORIMETRY, DIFFERENTIAL SCANNING; FABACEAE; LIPIDS; MICROSCOPY, ELECTRON, SCANNING; NANOSTRUCTURES; ONDANSETRON; PARTICLE SIZE; POLYMERS; SHEEP; SURFACE PROPERTIES; TISSUE DISTRIBUTION; X-RAY DIFFRACTION;

EID: 84904281871     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2014.06.037     Document Type: Article

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