Is the alcohol deprivation effect genetically mediated? Studies with HXB/BXH recombinant inbred rat strains

Alcoholism: Clinical and Experimental Research

Volumn 38, Issue 7, 2014, Pages 2148-2157

  Vanderlinden, Lauren A ^a   Saba, Laura M ^a   Printz, Morton P ^b   Flodman, Pamela ^c   Koob, George ^d,f   Richardson, Heather N ^d,g   Hoffman, Paula L ^e   Tabakoff, Boris ^a,e  

^a UNIVERSITY OF COLORADO   (United States)

^b San Diego   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^f NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^g UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Alcohol consumption; Alcohol deprivation effect; Heritability; HXB BXH recombinant inbred rat strains; Quantitative trait loci

Indexed keywords

ALCOHOL; WATER;

ALCOHOL ABSTINENCE; ALCOHOL CONSUMPTION; ALCOHOL DEPRIVATION EFFECT; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BROWN NORWAY RAT; CHROMOSOME 1; CHROMOSOME 12; CHROMOSOME 2; CHROMOSOME 6; CONTROLLED STUDY; FLUID INTAKE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HERITABILITY; HXB BXH RECOMBINANT INBRED RAT STRAIN; INBRED RAT STRAIN; MALE; NONHUMAN; PHENOTYPE; POPULATION STRUCTURE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE TRAIT LOCUS; RAT; RELAPSE; SINGLE NUCLEOTIDE POLYMORPHISM; SPONTANEOUSLY HYPERTENSIVE RAT; ADDICTION; ANIMAL; DECISION MAKING; DRINKING BEHAVIOR; GENETICS; PSYCHOLOGY; QUANTITATIVE TRAIT; SPECIES DIFFERENCE;

ALCOHOL DRINKING; ALCOHOLISM; ANIMALS; BEHAVIOR, ADDICTIVE; CHOICE BEHAVIOR; GENOTYPE; MALE; PHENOTYPE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE; RATS; RATS, INBRED STRAINS; SPECIES SPECIFICITY;

EID: 84904279257     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12471     Document Type: Article

References (50)

1. Anton RF, O'Malley SS, Ciraulo DA, Cisler RA, Couper D, Donovan DM, Gastfriend DR, Hosking JD, Johnson BA, LoCastro JS, Longabaugh R, Mason BJ, Mattson ME, Miller WR, Pettinati HM, Randall CL, Swift R, Weiss RD, Williams LD, Zweben A (2006) Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA 295:2003-2017.
2. Becker HC, Lopez MF (2004) Increased ethanol drinking after repeated chronic ethanol exposure and withdrawal experience in C57BL/6 mice. Alcohol Clin Exp Res 28:1829-1838.
3. Bell RL, Rodd ZA, Boutwell CL, Hsu CC, Lumeng L, Murphy JM, Li TK, McBride WJ (2004) Effects of long-term episodic access to ethanol on the expression of an alcohol deprivation effect in low alcohol-consuming rats. Alcohol Clin Exp Res 28:1867-1874.
4. Bell RL, Rodd ZA, Schultz JA, Peper CL, Lumeng L, Murphy JM, McBride WJ (2008) Effects of short deprivation and re-exposure intervals on the ethanol drinking behavior of selectively bred high alcohol-consuming rats. Alcohol 42:407-416.
5. Bossert JM, Marchant NJ, Calu DJ, Shaham Y (2013) The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology 229:453-476.
6. Breese GR, Sinha R, Heilig M (2011) Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse. Pharmacol Ther 129:149-171.
7. Broman KW, Wu H, Sen S, Churchill GA (2003) R/qtl: QTL mapping in experimental crosses. Bioinformatics 19:889-890.
8. Camarini R, Hodge CW (2004) Ethanol preexposure increases ethanol self-administration in C57BL/6J and DBA/2J mice. Pharmacol Biochem Behav 79:623-632.
9. Carlborg O, De Koning DJ, Manly KF, Chesler E, Williams RW, Haley CS (2005) Methodological aspects of the genetic dissection of gene expression. Bioinformatics 21:2383-2393.
10. Carter BL, Tiffany ST (1999) Meta-analysis of cue-reactivity in addiction research. Addiction 94:327-340.
11. Churchill GA, Doerge RW (1994) Empirical threshold values for quantitative trait mapping. Genetics 138:963-971.
12. Colombo G, Lobina C, Carai MA, Gessa GL (2006) Phenotypic characterization of genetically selected Sardinian alcohol-preferring (sP) and -non-preferring (sNP) rats. Addict Biol 11:324-338.
13. Cox BR, Olney JJ, Lowery-Gionta EG, Sprow GM, Rinker JA, Navarro M, Kash TL, Thiele TE (2013) Repeated cycles of binge-like ethanol (EtOH)-drinking in male C57BL/6J mice augments subsequent voluntary EtOH intake but not other dependence-like phenotypes. Alcohol Clin Exp Res 37:1688-1695.
14. Crabbe JC, Harkness JH, Spence SE, Huang LC, Metten P (2012) Intermittent availability of ethanol does not always lead to elevated drinking in mice. Alcohol Alcohol 47:509-517.
15. Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, Styrkarsdottir U, Gretarsdottir S, Magnusson KP, Stefansson H, Fossdal R, Kristjansson K, Gislason HG, Stefansson T, Leifsson BG, Thorsteinsdottir U, Lamb JR, Gulcher JR, Reitman ML, Kong A, Schadt EE, Stefansson K (2008) Genetics of gene expression and its effect on disease. Nature 452:423-428.
16. Falconer DS, Mackay TFC (1996) Introduction to Quantitative Genetics. 4th ed. Longman Group Ltd., Essex, UK.
17. Gilpin NW, Richardson HN, Lumeng L, Koob GF (2008) Dependence-induced alcohol drinking by alcohol-preferring (P) rats and outbred Wistar rats. Alcohol Clin Exp Res 32:1688-1696.
18. Heyser CJ, Schulteis G, Koob GF (1997) Increased ethanol self-administration after a period of imposed ethanol deprivation in rats trained in a limited access paradigm. Alcohol Clin Exp Res 21:784-791.
19. Kent WJ (2002) BLAT-the BLAST-like alignment tool. Genome Res 12:656-664.
20. Koob GF, Le Moal M (1997) Drug abuse: hedonic homeostatic dysregulation. Science 278:52-58.
21. Le A, Shaham Y (2002) Neurobiology of relapse to alcohol in rats. Pharmacol Ther 94:137-156.
22. Li J, Burmeister M (2005) Genetical genomics: combining genetics with gene expression analysis. Hum Mol Genet 14 Spec No. 2: R163-9.
23. Li TK, Lumeng L, Doolittle DP (1993) Selective breeding for alcohol preference and associated responses. Behav Genet 23:163-170.
24. Lopez MF, Becker HC (2005) Effect of pattern and number of chronic ethanol exposures on subsequent voluntary ethanol intake in C57BL/6J mice. Psychopharmacology 181:688-696.
25. Lumeng L, Hawkins DT, Li TK (1977) New strains of rats with alcohol preference and nonpreference, in Alcohol and Aldehyde Metabolizing Systems, Vol. 3 (Thurman RG ed), pp 537-544. Academic Press, New York, NY.
26. Martin-Fardon R, Weiss F (2013) Modeling relapse in animals. Curr Top Behav Neurosci 13:403-432.
27. McBride WJ, Li TK (1998) Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol 12:339-369.
28. McKinzie DL, Eha R, Murphy JM, McBride WJ, Lumeng L, Li TK (1996) Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD rat lines. Alcohol Clin Exp Res 20:682-687.
29. Murphy JM, Stewart RB, Bell RL, Badia-Elder NE, Carr LG, McBride WJ, Lumeng L, Li TK (2002) Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference. Behav Genet 32:363-388.
30. O'Brien CP (2005) Anticraving medications for relapse prevention: a possible new class of psychoactive medications. Am J Psychiatry 162:1423-1431.
31. O'Dell LE, Roberts AJ, Smith RT, Koob GF (2004) Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure. Alcohol Clin Exp Res 28:1676-1682.
32. Printz MP, Jirout M, Jaworski R, Alemayehu A, Kren V (2003) Genetic models in applied physiology. HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics. J Appl Physiol (1985) 94: 2510-2522.
33. Roberts AJ, Heyser CJ, Cole M, Griffin P, Koob GF (2000) Excessive ethanol drinking following a history of dependence: animal model of allostasis. Neuropsychopharmacology 22:581-594.
34. Rodd ZA, Bell RL, Kuc KA, Murphy JM, Lumeng L, Li TK, McBride WJ (2003) Effects of repeated alcohol deprivations on operant ethanol self-administration by alcohol-preferring (P) rats. Neuropsychopharmacology 28:1614-1621.
35. Rodd-Henricks ZA, McKinzie DL, Murphy JM, McBride WJ, Lumeng L, Li TK (2000a) The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent on repeated deprivations. Alcohol Clin Exp Res 24:747-753.
36. Rodd-Henricks ZA, McKinzie DL, Shaikh SR, Murphy JM, McBride WJ, Lumeng L, Li TK (2000b) Alcohol deprivation effect is prolonged in the alcohol preferring (P) rat after repeated deprivations. Alcohol Clin Exp Res 24:8-16.
37. Rosenwasser AM, Fixaris MC, Crabbe JC, Brooks PC, Ascheid S (2013) Escalation of intake under intermittent ethanol access in diverse mouse genotypes. Addict Biol 18:496-507.
38. Sajja RK, Rahman S (2013) Nicotinic receptor partial agonists modulate alcohol deprivation effect in C57BL/6J mice. Pharmacol Biochem Behav 110:161-167.
39. Salimov R, Salimova N, Klodt P, Maisky A (1993) Interaction between alcohol deprivation and morphine withdrawal in mice. Drug Alcohol Depend 34:59-66.
40. Salimov R, Salimova N, Ratkin A, Shvets L, Maisky A (1995) Genetic control of alcohol deprivation effect in congenic mice. Alcohol 12:469-474.
41. Schadt EE, Monks SA, Drake TA, Lusis AJ, Che N, Colinayo V, Ruff TG, Milligan SB, Lamb JR, Cavet G, Linsley PS, Mao M, Stoughton RB, Friend SH (2003) Genetics of gene expression surveyed in maize, mouse and man. Nature 422:297-302.
42. Sinclair JD, Li TK (1989) Long and short alcohol deprivation: effects on AA and P alcohol-preferring rats. Alcohol 6:505-509.
43. Sinclair JD, Senter RJ (1967) Increased preference for ethanol in rats following deprivation. Psychon Sci 8:11-12.
44. Sommer W, Hyytia P, Kiianmaa K (2006) The alcohol-preferring AA and alcohol-avoiding ANA rats: neurobiology of the regulation of alcohol drinking. Addict Biol 11:289-309.
45. Spanagel R, Holter SM (1999) Long-term alcohol self-administration with repeated alcohol deprivation phases: an animal model of alcoholism? Alcohol Alcohol 34:231-243.
46. Spence JP, Liang T, Liu L, Johnson PL, Foroud T, Carr LG, Shekhar A (2009) From QTL to candidate gene: a genetic approach to alcoholism research. Curr Drug Abuse Rev 2:127-134.
47. Suchankova P, Steensland P, Fredriksson I, Engel JA, Jerlhag E (2013) Ghrelin receptor (GHS-R1A) antagonism suppresses both alcohol consumption and the alcohol deprivation effect in rats following long-term voluntary alcohol consumption. PLoS ONE 8:e71284.
48. Tabakoff B, Saba L, Printz M, Flodman P, Hodgkinson C, Goldman D, Koob G, Richardson HN, Kechris K, Bell RL, Hubner N, Heinig M, Pravenec M, Mangion J, Legault L, Dongier M, Conigrave KM, Whitfield JB, Saunders J, Grant B, Hoffman PL (2009) Genetical genomic determinants of alcohol consumption in rats and humans. BMC Biol 7:70.
49. Vengeliene V, Siegmund S, Singer MV, Sinclair JD, Li TK, Spanagel R (2003) A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake. Alcohol Clin Exp Res 27:1048-1054.
50. Vinuela A, Snoek LB, Riksen JA, Kammenga JE (2012) Aging uncouples heritability and expression-qtl in Caenorhabditis elegans. G3 (Bethesda) 2: 597-605.