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Volumn 2, Issue 2, 2009, Pages 127-134

From QTL to candidate gene: A genetic approach to alcoholism research

Author keywords

Alcoholism; Alpha synuclein (Snca); Candidate gene; Corticotrophin releasing factor receptor 2 (Crhr2); Neuropeptide Y (Npy); QTL mapping; Selective breeding

Indexed keywords

ALCOHOL; ALPHA SYNUCLEIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR 2; LEUCINE; NEUROPEPTIDE Y; PROLINE; UNCLASSIFIED DRUG; CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 2;

EID: 70349899234     PISSN: 18744737     EISSN: None     Source Type: Journal    
DOI: 10.2174/1874473710902020127     Document Type: Article
Times cited : (27)

References (61)
  • 1
    • 15944376562 scopus 로고    scopus 로고
    • Strategies for mapping and cloning quantitative trait genes in rodents
    • Flint J, Valdar W, Shifman S, Mott R. Strategies for mapping and cloning quantitative trait genes in rodents. Nat Rev Genet 2005; 6: 271-86.
    • (2005) Nat Rev Genet , vol.6 , pp. 271-286
    • Flint, J.1    Valdar, W.2    Shifman, S.3    Mott, R.4
  • 2
    • 0031815148 scopus 로고    scopus 로고
    • A quantitative trait locus for alcohol consumption in selectively bred rat lines
    • Carr LG, Foroud T, Bice P, et al. A quantitative trait locus for alcohol consumption in selectively bred rat lines. Alcohol Clin Exp Res 1998; 22: 884-7.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 884-887
    • Carr, L.G.1    Foroud, T.2    Bice, P.3
  • 4
    • 0026363055 scopus 로고
    • Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking
    • Li TK, Lumeng L, Doolittle DP, Carr LG. Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking. Alcohol Alcohol Suppl 1991; 1: 121-4.
    • (1991) Alcohol Alcohol Suppl , vol.1 , pp. 121-124
    • Li, T.K.1    Lumeng, L.2    Doolittle, D.P.3    Carr, L.G.4
  • 6
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • McBride WJ, Li TK. Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol 1998; 12: 339-69.
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 7
    • 0036751424 scopus 로고    scopus 로고
    • Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference
    • Murphy JM, Stewart RB, Bell RL, et al. Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low alcohol preference. Behav Genet 2002; 32: 363-88.
    • (2002) Behav Genet , vol.32 , pp. 363-388
    • Murphy, J.M.1    Stewart, R.B.2    Bell, R.L.3
  • 8
    • 0034566497 scopus 로고    scopus 로고
    • Selected lines and inbred strains. Tools in the hunt for the genes involved in alcoholism
    • Review
    • Grahame NJ. Selected lines and inbred strains. Tools in the hunt for the genes involved in alcoholism. Alcohol Res Health 2000; 24: 159-63. Review.
    • (2000) Alcohol Res Health , vol.24 , pp. 159-163
    • Grahame, N.J.1
  • 9
    • 0032569940 scopus 로고    scopus 로고
    • Ethanol consumption and resistance are inversely related to neuropeptide Y levels
    • Thiele TE, Marsh DJ, Ste-Marie L, Bernstein IL, Palmiter RD. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature 1998; 396: 366-9.
    • (1998) Nature , vol.396 , pp. 366-369
    • Thiele, T.E.1    Marsh, D.J.2    Ste-Marie, L.3    Bernstein, I.L.4    Palmiter, R.D.5
  • 11
    • 0037648675 scopus 로고    scopus 로고
    • Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence
    • Gilpin NW, Stewart RB, Murphy JM, Li TK, Badia-Elder NE. Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence. Alcohol Clin Exp Res 2003; 27: 787-94.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 787-794
    • Gilpin, N.W.1    Stewart, R.B.2    Murphy, J.M.3    Li, T.K.4    Badia-Elder, N.E.5
  • 12
    • 2942696164 scopus 로고    scopus 로고
    • Increased anxiety-like behavior and ethanol self-administration in dependent rats: Reversal via corticotropin-releasing factor-2 receptor activation
    • Valdez GR, Sabino V, Koob GF. Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activation. Alcohol Clin Exp Res 2004; 28: 865-72.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 865-872
    • Valdez, G.R.1    Sabino, V.2    Koob, G.F.3
  • 13
    • 34250175137 scopus 로고    scopus 로고
    • A CRF(2) agonist administered into the central nucleus of the amygdala decreases ethanol self-administration in ethanol-dependent rats
    • Funk CK, Koob GF. A CRF(2) agonist administered into the central nucleus of the amygdala decreases ethanol self-administration in ethanol-dependent rats. Brain Res 2007; 1155: 172-8.
    • (2007) Brain Res , vol.1155 , pp. 172-178
    • Funk, C.K.1    Koob, G.F.2
  • 14
    • 0036714864 scopus 로고    scopus 로고
    • A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States
    • Lappalainen J, Kranzler HR, Malison R, et al. A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States. Arch Gen Psychiatry 2002; 59: 825-31.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 825-831
    • Lappalainen, J.1    Kranzler, H.R.2    Malison, R.3
  • 15
    • 12244258210 scopus 로고    scopus 로고
    • NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations
    • Zhu G, Pollak L, Mottagui-Tabar S, et al. NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcohol Clin Exp Res 2003; 27: 19-24.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 19-24
    • Zhu, G.1    Pollak, L.2    Mottagui-Tabar, S.3
  • 16
    • 18844374771 scopus 로고    scopus 로고
    • Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving
    • Bonsch D, Greifenberg V, Bayerlein K, et al. Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving. Alcohol Clin Exp Res 2005; 29: 763-5.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 763-765
    • Bonsch, D.1    Greifenberg, V.2    Bayerlein, K.3
  • 17
    • 33947246702 scopus 로고    scopus 로고
    • Association of alcohol craving with alpha-synuclein (SNCA)
    • Foroud T, Wetherill LF, Liang T, et al. Association of alcohol craving with alpha-synuclein (SNCA). Alcohol Clin Exp Res 2007; 31: 537-45.
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 537-545
    • Foroud, T.1    Wetherill, L.F.2    Liang, T.3
  • 18
    • 0024508964 scopus 로고
    • Mapping mendelian factors underlying quantitative traits using RFLP linkage maps
    • Lander ES, Botstein D. Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 1989; 121: 185-99.
    • (1989) Genetics , vol.121 , pp. 185-199
    • Lander, E.S.1    Botstein, D.2
  • 19
    • 0032407814 scopus 로고    scopus 로고
    • Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines
    • Bice P, Foroud T, Bo R, et al. Genomic screen for QTLs underlying alcohol consumption in the P and NP rat lines. Mamm Genome 1998; 9: 949-55.
    • (1998) Mamm Genome , vol.9 , pp. 949-955
    • Bice, P.1    Foroud, T.2    Bo, R.3
  • 20
    • 0034487868 scopus 로고    scopus 로고
    • Congenic strains developed for alcohol- and drug-related phenotypes
    • Bennett B. Congenic strains developed for alcohol- and drug-related phenotypes. Pharmacol Biochem Behav 2000; 67: 671-81.
    • (2000) Pharmacol Biochem Behav , vol.67 , pp. 671-681
    • Bennett, B.1
  • 21
    • 33646368181 scopus 로고    scopus 로고
    • Development of congenic rat strains for alcohol consumption derived from the alcohol-preferring and nonpreferring rats
    • Carr LG, Habegger K, Spence JP, Liu L, Lumeng L, Foroud T. Development of congenic rat strains for alcohol consumption derived from the alcohol-preferring and nonpreferring rats. Behav Genet 2006; 36: 285-90.
    • (2006) Behav Genet , vol.36 , pp. 285-290
    • Carr, L.G.1    Habegger, K.2    Spence, J.P.3    Liu, L.4    Lumeng, L.5    Foroud, T.6
  • 23
    • 47249098328 scopus 로고    scopus 로고
    • Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3
    • Kozell L, Belknap JK, Hofstetter JR, Mayeda A, Buck KJ. Mapping a locus for alcohol physical dependence and associated withdrawal to a 1.1 Mb interval of mouse chromosome 1 syntenic with human chromosome 1q23.2-23.3. Genes Brain Behav 2008; 7: 560-7.
    • (2008) Genes Brain Behav , vol.7 , pp. 560-567
    • Kozell, L.1    Belknap, J.K.2    Hofstetter, J.R.3    Mayeda, A.4    Buck, K.J.5
  • 24
    • 9244236072 scopus 로고    scopus 로고
    • Confirmation and genetic dissection of a major quantitative trait locus for alcohol preference drinking
    • Ruf C, Carosone-Link P, Springett J, Bennett B. Confirmation and genetic dissection of a major quantitative trait locus for alcohol preference drinking. Alcohol Clin Exp Res 2004; 28: 1613-21.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 1613-1621
    • Ruf, C.1    Carosone-Link, P.2    Springett, J.3    Bennett, B.4
  • 25
    • 0034672582 scopus 로고    scopus 로고
    • Multiple seizure susceptibility genes on chromosome 7 in SWXL-4 congenic mouse strains
    • Legare ME, Frankel WN. Multiple seizure susceptibility genes on chromosome 7 in SWXL-4 congenic mouse strains. Genomics 2000; 70: 62-5.
    • (2000) Genomics , vol.70 , pp. 62-65
    • Legare, M.E.1    Frankel, W.N.2
  • 26
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • Morel L, Blenman KR, Croker BP, Wakeland EK. The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc Natl Acad Sci USA 2001; 98: 1787-92.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 27
    • 0037446854 scopus 로고    scopus 로고
    • alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats
    • Liang T, Spence J, Liu L, et al. alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats. 2003; Proc Natl Acad Sci USA 100: 4690-5.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4690-4695
    • Liang, T.1    Spence, J.2    Liu, L.3
  • 28
    • 34250616601 scopus 로고    scopus 로고
    • Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains
    • Carr LG, Kimpel MW, Liang T, et al. Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. Alcohol Clin Exp Res 2007; 31: 1089-98.
    • (2007) Alcohol Clin Exp Res , vol.31 , pp. 1089-1098
    • Carr, L.G.1    Kimpel, M.W.2    Liang, T.3
  • 29
    • 12444259663 scopus 로고    scopus 로고
    • Expression profiling and QTL analysis: A powerful complementary strategy in drug abuse research
    • Spence J, Liang T, Foroud T, Lo D, Carr L. Expression profiling and QTL analysis: a powerful complementary strategy in drug abuse research. Addict Biol 2005; 10: 47-51.
    • (2005) Addict Biol , vol.10 , pp. 47-51
    • Spence, J.1    Liang, T.2    Foroud, T.3    Lo, D.4    Carr, L.5
  • 30
    • 12444257327 scopus 로고    scopus 로고
    • DNA microarrays and expression profiling in drug abuse research
    • Gebicke-Haerter PJ, Sommer WH. DNA microarrays and expression profiling in drug abuse research. Addict Biol 2005; 10: 1-3.
    • (2005) Addict Biol , vol.10 , pp. 1-3
    • Gebicke-Haerter, P.J.1    Sommer, W.H.2
  • 31
    • 12444306306 scopus 로고    scopus 로고
    • Gene expression in animals with different acute responses to ethanol
    • Hoffman P, Tabakoff B. Gene expression in animals with different acute responses to ethanol. Addict Biol 2005; 10: 63-9.
    • (2005) Addict Biol , vol.10 , pp. 63-69
    • Hoffman, P.1    Tabakoff, B.2
  • 32
    • 28844475242 scopus 로고    scopus 로고
    • Addiction and its brain science
    • Spanagel R, Heilig M. Addiction and its brain science. Addiction 2005; 100: 1813-22.
    • (2005) Addiction , vol.100 , pp. 1813-1822
    • Spanagel, R.1    Heilig, M.2
  • 33
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3
  • 34
    • 0034051658 scopus 로고    scopus 로고
    • TOGA: An automated parsing technology for analyzing expression of nearly all genes
    • Sutcliffe JG, Foye PE, Erlander MG, et al. TOGA: an automated parsing technology for analyzing expression of nearly all genes. Proc Natl Acad Sci USA 2000; 97: 1976-81.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1976-1981
    • Sutcliffe, J.G.1    Foye, P.E.2    Erlander, M.G.3
  • 35
    • 34248644018 scopus 로고    scopus 로고
    • Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions
    • Kimpel MW, Strother WN, McClintick JN, et al. Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. Alcohol 2007; 41: 95-132.
    • (2007) Alcohol , vol.41 , pp. 95-132
    • Kimpel, M.W.1    Strother, W.N.2    McClintick, J.N.3
  • 36
    • 14644390950 scopus 로고    scopus 로고
    • Effect of polymorphism on expression of the neuropeptide Y gene in inbred alcohol-preferring and -nonpreferring rats
    • Spence JP, Liang T, Habegger K, Carr LG. Effect of polymorphism on expression of the neuropeptide Y gene in inbred alcohol-preferring and -nonpreferring rats. Neuroscience 2005; 131: 871-6.
    • (2005) Neuroscience , vol.131 , pp. 871-876
    • Spence, J.P.1    Liang, T.2    Habegger, K.3    Carr, L.G.4
  • 37
    • 77951590385 scopus 로고    scopus 로고
    • Polymorphism in the Corticotrophin-releasing factor 2 receptor of alcohol-preferring and alcohol-nonpreferring rats
    • Liang T, Watts V, Carr LG. Polymorphism in the Corticotrophin-releasing factor 2 receptor of alcohol-preferring and alcohol-nonpreferring rats. Alcohol Clin Exp Res 2006; 30: 124A.
    • (2006) Alcohol Clin Exp Res , vol.124 A , pp. 30
    • Liang, T.1    Watts, V.2    Carr, L.G.3
  • 38
    • 0031760196 scopus 로고    scopus 로고
    • Neuropeptide Y levels in ethanol-naive alcohol-preferring and nonpreferring rats and in Wistar rats after ethanol exposure
    • Ehlers CL, Li TK, Lumeng L, et al. Neuropeptide Y levels in ethanol-naive alcohol-preferring and nonpreferring rats and in Wistar rats after ethanol exposure. Alcohol Clin Exp Res 1998; 22: 1778-82.
    • (1998) Alcohol Clin Exp Res , vol.22 , pp. 1778-1782
    • Ehlers, C.L.1    Li, T.K.2    Lumeng, L.3
  • 39
    • 77951535578 scopus 로고    scopus 로고
    • Quantitative trait loci for body weight identified in male inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats
    • Spence JP, Liu L, Foroud T, Carr LG, Shekhar A. Quantitative trait loci for body weight identified in male inbred alcohol-preferring (iP) and -nonpreferring (iNP) rats. Alcohol Clin Exp Res 2007; 31: 134A.
    • (2007) Alcohol Clin Exp Res , vol.134 A , pp. 31
    • Spence, J.P.1    Liu, L.2    Foroud, T.3    Carr, L.G.4    Shekhar, A.5
  • 40
    • 77951599331 scopus 로고    scopus 로고
    • NPY, SNCA, Spr and Gtrap3-18 genes are strongly correlated with bone mass and strength phenotypes on congenic P/NP rats
    • Alam I, Carr LG, Lumeng L, Edenberg HJ, Econs MJ, Turner CH. NPY, SNCA, Spr and Gtrap3-18 genes are strongly correlated with bone mass and strength phenotypes on congenic P/NP rats. J Bone Miner Res 2006; 21: S145.
    • (2006) J Bone Miner Res , vol.21
    • Alam, I.1    Carr, L.G.2    Lumeng, L.3    Edenberg, H.J.4    Econs, M.J.5    Turner, C.H.6
  • 42
    • 0032981008 scopus 로고    scopus 로고
    • Innate differences of neuropeptide Y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference
    • Hwang BH, Zhang JK, Ehlers CL, Lumeng L, Li TK. Innate differences of neuropeptide Y (NPY) in hypothalamic nuclei and central nucleus of the amygdala between selectively bred rats with high and low alcohol preference. Alcohol Clin Exp Res 1999; 23: 1023-30.
    • (1999) Alcohol Clin Exp Res , vol.23 , pp. 1023-1030
    • Hwang, B.H.1    Zhang, J.K.2    Ehlers, C.L.3    Lumeng, L.4    Li, T.K.5
  • 43
    • 0027516283 scopus 로고
    • Comparison of alcohol-preferring (P) and nonpreferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol
    • Stewart RB, Gatto GJ, Lumeng L, Li TK, Murphy JM. Comparison of alcohol-preferring (P) and nonpreferring (NP) rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol 1993; 10: 1-10.
    • (1993) Alcohol , vol.10 , pp. 1-10
    • Stewart, R.B.1    Gatto, G.J.2    Lumeng, L.3    Li, T.K.4    Murphy, J.M.5
  • 44
    • 0034070207 scopus 로고    scopus 로고
    • Acoustic startle and fear-potentiated startle in alcohol-preferring (P) and -nonpreferring (NP) lines of rats
    • McKinzie DL, Sajdyk TJ, McBride WJ, et al. Acoustic startle and fear-potentiated startle in alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacol Biochem Behav 2000; 65: 691-6.
    • (2000) Pharmacol Biochem Behav , vol.65 , pp. 691-696
    • McKinzie, D.L.1    Sajdyk, T.J.2    McBride, W.J.3
  • 45
    • 38549123307 scopus 로고    scopus 로고
    • Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia
    • Sajdyk TJ, Johnson PL, Leitermann RJ, et al. Neuropeptide Y in the amygdala induces long-term resilience to stress-induced reductions in social responses but not hypothalamic-adrenal-pituitary axis activity or hyperthermia. J Neurosci 2008; 28: 893-903.
    • (2008) J Neurosci , vol.28 , pp. 893-903
    • Sajdyk, T.J.1    Johnson, P.L.2    Leitermann, R.J.3
  • 46
    • 4344566929 scopus 로고    scopus 로고
    • Interactions between NPY and CRF in the amygdala to regulate emotionality
    • Sajdyk TJ, Shekhar A, Gehlert DR. Interactions between NPY and CRF in the amygdala to regulate emotionality. Neuropeptides. 2004; 38: 225-34.
    • (2004) Neuropeptides , vol.38 , pp. 225-234
    • Sajdyk, T.J.1    Shekhar, A.2    Gehlert, D.R.3
  • 47
    • 4344622379 scopus 로고    scopus 로고
    • The NPY system in stress, anxiety and depression
    • Review
    • Heilig M. The NPY system in stress, anxiety and depression. Neuropeptides 2004; 38: 213-24. Review.
    • (2004) Neuropeptides , vol.38 , pp. 213-224
    • Heilig, M.1
  • 48
    • 0036278335 scopus 로고    scopus 로고
    • Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
    • Xu J, Kao SY, Lee FJ, Song W, Jin LW, Yankner BA. Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease. Nat Med 2002; 8: 600-6.
    • (2002) Nat Med , vol.8 , pp. 600-606
    • Xu, J.1    Kao, S.Y.2    Lee, F.J.3    Song, W.4    Jin, L.W.5    Yankner, B.A.6
  • 49
    • 0035834360 scopus 로고    scopus 로고
    • Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
    • Conway KA, Rochet JC, Bieganski RM, Lansbury PT. Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science 2001; 294: 1346-9.
    • (2001) Science , vol.294 , pp. 1346-1349
    • Conway, K.A.1    Rochet, J.C.2    Bieganski, R.M.3    Lansbury, P.T.4
  • 50
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
    • Lee FJ, Liu F, Pristupa ZB, Niznik HB. Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J 2001; 15: 916-26.
    • (2001) FASEB J , vol.15 , pp. 916-926
    • Lee, F.J.1    Liu, F.2    Pristupa, Z.B.3    Niznik, H.B.4
  • 52
    • 0037451858 scopus 로고    scopus 로고
    • Attenuation of dopamine transporter activity by alpha-synuclein
    • Wersinger C, Sidhu A. Attenuation of dopamine transporter activity by alpha-synuclein. Neurosci Lett 2003; 340: 189-92.
    • (2003) Neurosci Lett , vol.340 , pp. 189-192
    • Wersinger, C.1    Sidhu, A.2
  • 53
    • 14944348552 scopus 로고    scopus 로고
    • The role of {alpha}-synuclein in both neuroprotection and neurodegeneration
    • Sidhu A, Wersinger C, Moussa CE, Vernier P. The role of {alpha}-synuclein in both neuroprotection and neurodegeneration. Ann NY Acad Sci 2004; 1035: 250-70.
    • (2004) Ann NY Acad Sci , vol.1035 , pp. 250-270
    • Sidhu, A.1    Wersinger, C.2    Moussa, C.E.3    Vernier, P.4
  • 54
    • 10944243102 scopus 로고    scopus 로고
    • Role of alpha-synuclein in presynaptic dopamine recruitment
    • Yavich L, Tanila H, Vepsalainen S, Jakala P. Role of alpha-synuclein in presynaptic dopamine recruitment. J Neurosci 2004; 24: 11165-70.
    • (2004) J Neurosci , vol.24 , pp. 11165-11170
    • Yavich, L.1    Tanila, H.2    Vepsalainen, S.3    Jakala, P.4
  • 55
    • 33749165901 scopus 로고    scopus 로고
    • Regulation of alpha-synuclein expression in alcohol-preferring and -non preferring rats
    • Liang T, Carr LG. Regulation of alpha-synuclein expression in alcohol-preferring and -non preferring rats. J Neurochem 2006; 99: 470-82.
    • (2006) J Neurochem , vol.99 , pp. 470-482
    • Liang, T.1    Carr, L.G.2
  • 56
    • 33744552229 scopus 로고    scopus 로고
    • Peripheral blood alpha-synuclein mRNA levels are elevated in cynomolgus monkeys that chronically self-administer ethanol
    • Walker SJ, Grant KA. Peripheral blood alpha-synuclein mRNA levels are elevated in cynomolgus monkeys that chronically self-administer ethanol. Alcohol 2006; 38: 1-4.
    • (2006) Alcohol , vol.38 , pp. 1-4
    • Walker, S.J.1    Grant, K.A.2
  • 58
    • 21044435021 scopus 로고    scopus 로고
    • Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice
    • Ziolkowska B, Gieryk A, Bilecki W, et al. Regulation of alpha-synuclein expression in limbic and motor brain regions of morphine-treated mice. J Neurosci 2005; 25: 4996-5003.
    • (2005) J Neurosci , vol.25 , pp. 4996-5003
    • Ziolkowska, B.1    Gieryk, A.2    Bilecki, W.3
  • 59
    • 39049097066 scopus 로고    scopus 로고
    • Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers
    • Mash DC, Adi N, Duque L, Pablo J, Kumar M, Ervin FR. Alpha synuclein protein levels are increased in serum from recently abstinent cocaine abusers. Drug Alcohol Depend 2008; 94: 246-50.
    • (2008) Drug Alcohol Depend , vol.94 , pp. 246-250
    • Mash, D.C.1    Adi, N.2    Duque, L.3    Pablo, J.4    Kumar, M.5    Ervin, F.R.6
  • 60
    • 1342281225 scopus 로고    scopus 로고
    • CRF and CRF receptors: Role in stress responsivity and other behaviors
    • Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 2004; 44: 525-57.
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 525-557
    • Bale, T.L.1    Vale, W.W.2
  • 61
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: From adaptation to disease
    • Review
    • de Kloet ER, Joels M, Holsboer F. Stress and the brain: from adaptation to disease. Nat Rev Neurosci 2005; 6: 463-75. Review.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 463-475
    • de Kloet, E.R.1    Joels, M.2    Holsboer, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.