Molecular conformation of the full-length tumor suppressor NF2/merlin - A small-angle neutron scattering study

Journal of Molecular Biology

Volumn 426, Issue 15, 2014, Pages 2755-2768

  Ali Khajeh, Jahan ^a   Ju, Jeong Ho ^a   Atchiba, Moussoubaou ^a   Allaire, Marc ^b   Stanley, Christopher ^c   Heller, William T ^c   Callaway, David J E ^a   Bu, Zimei ^a  

^a CITY COLLEGE OF NEW YORK   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

Ezrin; Merlin; neurofibromatosis type 2; phosphatidylinositol 4,5 bisphosphate; small angle neutron scattering

Indexed keywords

MERLIN; MERLIN(S518D) PROTEIN; MUTANT PROTEIN; NHERF1 PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN; UNCLASSIFIED DRUG; EZRIN; MOESIN;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; HUMAN; NEUTRON SCATTERING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; WILD TYPE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHEMICAL STRUCTURE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; DISSOCIATION CONSTANT; FLUORESCENCE RESONANCE ENERGY TRANSFER; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR SIZE; MOLECULAR WEIGHT; MUTATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; STATIC ELECTRICITY; SURFACE PLASMON RESONANCE; ULTRACENTRIFUGATION;

EZRIN; MERLIN; NEUROFIBROMATOSIS TYPE 2; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE; SMALL-ANGLE NEUTRON SCATTERING;

CALORIMETRY; CIRCULAR DICHROISM; GENES, TUMOR SUPPRESSOR; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NEUROFIBROMIN 2; NEUTRON DIFFRACTION; PHOSPHOPROTEINS; PHOSPHORYLATION; SCATTERING, SMALL ANGLE; SODIUM-HYDROGEN ANTIPORTER; SURFACE PLASMON RESONANCE;

EID: 84904268344     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.05.011     Document Type: Article

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