Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in down syndrome

Genetics

Volumn 197, Issue 3, 2014, Pages 899-912

  Sahún, Ignasi ^a   Marechal, Damien ^b,c,d   Pereira, Patricia Lopes ^b,h   Nalesso, Valérie ^b,c,d   Gruart, Agnes ^e   Garcia, José Maria Delgado ^e   Antonarakis, Stylianos E ^f   Dierssen, Mara ^a   Herault, Yann ^b,c,d,g  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c INSERM   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^f UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^g INSTITUT CLINIQUE DE LA SOURIS   (France)

^h CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4,5,6,7 TETRAHYDROISOXAZOLO[4,5 C]PYRIDIN 3 OL; ABC TRANSPORTER G1; ANAPHASE PROMOTING COMPLEX SUBUNIT 1; BONE MORPHOGENETIC PROTEIN 2; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR SOX2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATIVE MEMORY; AUTISM; BRAIN ELECTROPHYSIOLOGY; CHROMOSOME ABERRATION; COGNITION; CONDITIONING; CONTROLLED STUDY; DENTATE GYRUS; DOWN SYNDROME; EXCITATORY POSTSYNAPTIC POTENTIAL; EXPLORATORY BEHAVIOR; FEAR; GENE EXPRESSION; GENOTYPE; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPUS; LEARNING; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; MONOSOMY; MORRIS WATER MAZE TEST; MOTOR COORDINATION; MOTOR PERFORMANCE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RECOGNITION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTAROD TEST; SHORT TERM MEMORY; SOCIAL BEHAVIOR; SOCIAL DISCRIMINATION; SOCIAL INTERACTION; SPATIAL LEARNING; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; CLUSTER ANALYSIS; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; GENOME; MOTOR ACTIVITY; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; BEHAVIOR, ANIMAL; CLUSTER ANALYSIS; COGNITION; CONDITIONING (PSYCHOLOGY); DISEASE MODELS, ANIMAL; DOWN SYNDROME; EXPLORATORY BEHAVIOR; GENE EXPRESSION REGULATION; GENOME; HIPPOCAMPUS; LEARNING; LONG-TERM POTENTIATION; MICE, INBRED C57BL; MONOSOMY; MOTOR ACTIVITY; NEURONAL PLASTICITY; SOCIAL BEHAVIOR;

EID: 84904268309     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.114.165241     Document Type: Article

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