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Volumn 9, Issue 7, 2014, Pages

Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEINASE; STRESS ACTIVATED PROTEIN KINASE 1; MAP2K4 PROTEIN, HUMAN; MMP2 PROTEIN, MOUSE;

EID: 84904251396     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102289     Document Type: Article
Times cited : (36)

References (48)
  • 3
    • 34248597048 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase kinase 4 in cancer
    • DOI 10.1038/sj.onc.1210410, PII 1210410
    • Whitmarsh AJ, Davis RJ (2007) Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene 26: 3172-3184. (Pubitemid 46763013)
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3172-3184
    • Whitmarsh, A.J.1    Davis, R.J.2
  • 4
    • 0032100617 scopus 로고    scopus 로고
    • Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene
    • Su GH, Hilgers W, Shekher MC, Tang DJ, Yeo CJ, et al. (1998) Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. Cancer Res 58: 2339-2342. (Pubitemid 28252690)
    • (1998) Cancer Research , vol.58 , Issue.11 , pp. 2339-2342
    • Su, G.H.1    Hilgers, W.2    Shekher, M.C.3    Tang, D.J.4    Yeo, C.J.5    Hruban, R.H.6    Kern, S.E.7
  • 6
    • 28244493042 scopus 로고    scopus 로고
    • 2-terminal kinase kinases JNKK1/MKK4 and MKK7
    • DOI 10.1158/0008-5472.CAN-05-2382
    • Vander Griend DJ, Kocherginsky M, Hickson JA, Stadler WM, Lin A, et al. (2005) Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7. Cancer Res 65: 10984-10991. (Pubitemid 41713368)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10984-10991
    • Vander, G.D.J.1    Kocherginsky, M.2    Hickson, J.A.3    Stadler, W.M.4    Lin, A.5    Rinker-Schaeffer, C.W.6
  • 7
    • 82255186525 scopus 로고    scopus 로고
    • MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression
    • Szmulewitz RZ, Clark R, Lotan T, Otto K, Taylor Veneris J, et al. (2012) MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression. Int J Cancer 130: 509-520.
    • (2012) Int J Cancer , vol.130 , pp. 509-520
    • Szmulewitz, R.Z.1    Clark, R.2    Lotan, T.3    Otto, K.4    Taylor Veneris, J.5
  • 9
    • 34547102745 scopus 로고    scopus 로고
    • Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: An important role for SAPK signalling in prostatic neoplasia
    • DOI 10.1002/path.2194
    • Lotan TL, Lyon M, Huo D, Taxy JB, Brendler C, et al. (2007) Up-regulation of MKK4, MKK6 and MKK7 during prostate cancer progression: an important role for SAPK signalling in prostatic neoplasia. J Pathol 212: 386-394. (Pubitemid 47099015)
    • (2007) Journal of Pathology , vol.212 , Issue.4 , pp. 386-394
    • Lotan, T.L.1    Lyon, M.2    Huo, D.3    Taxy, J.B.4    Brendler, C.5    Foster, B.A.6    Stadler, W.7    Rinker-Schaeffer, C.W.8
  • 11
    • 69249083967 scopus 로고    scopus 로고
    • MEK4 function, genistein treatment, and invasion of human prostate cancer cells
    • Xu L, Ding Y, Catalona WJ, Yang XJ, Anderson WF, et al. (2009) MEK4 function, genistein treatment, and invasion of human prostate cancer cells. J Natl Cancer Inst 101: 1141-1155.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1141-1155
    • Xu, L.1    Ding, Y.2    Catalona, W.J.3    Yang, X.J.4    Anderson, W.F.5
  • 12
    • 17144426480 scopus 로고    scopus 로고
    • Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells
    • Huang X, Chen S, Xu L, Liu Y, Deb DK, et al. (2005) Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells. Cancer Res 65: 3470-3478. (Pubitemid 40524634)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3470-3478
    • Huang, X.1    Chen, S.2    Xu, L.3    Liu, Y.4    Deb, D.K.5    Platanias, L.C.6    Bergan, R.C.7
  • 14
    • 0043068003 scopus 로고    scopus 로고
    • p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion
    • DOI 10.1038/sj.onc.1206730
    • Hayes SA, Huang X, Kambhampati S, Platanias LC, Bergan RC (2003) p38 MAP kinase modulates Smad-dependent changes in human prostate cell adhesion. Oncogene 22: 4841-4850. (Pubitemid 36981272)
    • (2003) Oncogene , vol.22 , Issue.31 , pp. 4841-4850
    • Hayes, S.A.1    Huang, X.2    Kambhampati, S.3    Platanias, L.C.4    Bergan, R.C.5
  • 15
    • 33646859435 scopus 로고    scopus 로고
    • MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer
    • DOI 10.1038/sj.onc.1209337, PII 1209337
    • Xu L, Chen S, Bergan RC (2006) MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer. Oncogene 25: 2987-2998. (Pubitemid 43780463)
    • (2006) Oncogene , vol.25 , Issue.21 , pp. 2987-2998
    • Xu, L.1    Chen, S.2    Bergan, R.C.3
  • 16
    • 33747618245 scopus 로고    scopus 로고
    • Genistein inhibits matrix metalloproteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway
    • DOI 10.1124/mol.106.023861
    • Xu L, Bergan RC (2006) Genistein Inhibits Matrix Metalloproteinase Type 2 Activation and Prostate Cancer Cell Invasion by Blocking the Transforming Growth Factor beta-Mediated Activation of Mitogen-Activated Protein Kinase- Activated Protein Kinase 2-27-kDa Heat Shock Protein Pathway. Mol Pharmacol 70: 869-877. (Pubitemid 44268444)
    • (2006) Molecular Pharmacology , vol.70 , Issue.3 , pp. 869-877
    • Xu, L.1    Bergan, R.C.2
  • 17
    • 4043110739 scopus 로고    scopus 로고
    • Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors
    • DOI 10.1038/sj.onc.1207802
    • Wang L, Pan Y, Dai JL (2004) Evidence of MKK4 pro-oncogenic activity in breast and pancreatic tumors. Oncogene 23: 5978-5985. (Pubitemid 39093542)
    • (2004) Oncogene , vol.23 , Issue.35 , pp. 5978-5985
    • Wang, L.1    Pan, Y.2    Jia, L.D.3
  • 18
    • 33646814635 scopus 로고    scopus 로고
    • Targeted deletion of MKK4 in cancer cells: A detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss
    • DOI 10.1158/0008-5472.CAN-06-0555
    • Cunningham SC, Gallmeier E, Hucl T, Dezentje DA, Calhoun ES, et al. (2006) Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss. Cancer Res 66: 5560-5564. (Pubitemid 43927105)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5560-5564
    • Cunningham, S.C.1    Gallmeier, E.2    Hucl, T.3    Dezentje, D.A.4    Calhoun, E.S.5    Falco, G.6    Abdelmohsen, K.7    Gorospe, M.8    Kern, S.E.9
  • 19
    • 33644502513 scopus 로고    scopus 로고
    • The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma
    • Hickson JA, Huo D, Vander Griend DJ, Lin A, Rinker-Schaeffer CW, et al. (2006) The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma. Cancer Res 66: 2264-2270.
    • (2006) Cancer Res , vol.66 , pp. 2264-2270
    • Hickson, J.A.1    Huo, D.2    Vander Griend, D.J.3    Lin, A.4    Rinker-Schaeffer, C.W.5
  • 21
    • 79952106612 scopus 로고    scopus 로고
    • Functional and clinicopathological analysis of loss of MKK4 expression in endometrial cancer
    • Ishikawa M, Nakayama K, Rahman MT, Rahman M, Katagiri A, et al. (2010) Functional and clinicopathological analysis of loss of MKK4 expression in endometrial cancer. Oncology 79: 238-246.
    • (2010) Oncology , vol.79 , pp. 238-246
    • Ishikawa, M.1    Nakayama, K.2    Rahman, M.T.3    Rahman, M.4    Katagiri, A.5
  • 23
    • 18744362140 scopus 로고    scopus 로고
    • Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion
    • DOI 10.1038/sj.onc.1206117
    • Liu Y, Jovanovic B, Pins M, Lee C, Bergan RC (2002) Over expression of endoglin in human prostate cancer suppresses cell detachment, migration and invasion. Oncogene 21: 8272-8281. (Pubitemid 35477867)
    • (2002) Oncogene , vol.21 , Issue.54 , pp. 8272-8281
    • Liu, Y.1    Jovanovic, B.2    Pins, M.3    Lee, C.4    Bergan, R.C.5
  • 24
    • 77955358312 scopus 로고    scopus 로고
    • Cell Line Verification Test Recommendations
    • ATCC
    • ATCC (2007) Cell Line Verification Test Recommendations. ATCC Technical Bulletin No.8: 1-3.
    • (2007) ATCC Technical Bulletin , Issue.8 , pp. 1-3
  • 26
    • 37349064255 scopus 로고    scopus 로고
    • Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells
    • DOI 10.1124/mol.107.038935
    • Craft CS, Xu L, Romero D, Vary CP, Bergan RC (2008) Genistein induces phenotypic reversion of endoglin deficiency in human prostate cancer cells. Mol Pharmacol 73: 235-242. (Pubitemid 350294214)
    • (2008) Molecular Pharmacology , vol.73 , Issue.1 , pp. 235-242
    • Craft, C.S.1    Xu, L.2    Romero, D.3    Vary, C.P.H.4    Bergan, R.C.5
  • 27
    • 38949133942 scopus 로고    scopus 로고
    • The methodology used to measure differential gene expression affects the outcome
    • Ding Y, Xu L, Jovanovic BD, Helenowski IB, Kelly DL, et al. (2007) The methodology used to measure differential gene expression affects the outcome. J Biomol Tech 18: 321-330.
    • (2007) J Biomol Tech , vol.18 , pp. 321-330
    • Ding, Y.1    Xu, L.2    Jovanovic, B.D.3    Helenowski, I.B.4    Kelly, D.L.5
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • -Delta DeltaCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh AJ, Shore P, Sharrocks AD, Davis RJ (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science 269: 403-407.
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sharrocks, A.D.3    Davis, R.J.4
  • 30
    • 17144426480 scopus 로고    scopus 로고
    • Genistein inhibits p38 map kinase activation, matrix metalloproteinase type 2, and cell invasion in human prostate epithelial cells
    • Huang X, Chen S, Xu L, Liu YQ, Deb DK, et al. (2005) Genistein inhibits p38 MAP kinase activation, MMP-2, and cell invasion in human prostate epithelial cells. Cancer Research 65: 3470-3478. (Pubitemid 40524634)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3470-3478
    • Huang, X.1    Chen, S.2    Xu, L.3    Liu, Y.4    Deb, D.K.5    Platanias, L.C.6    Bergan, R.C.7
  • 31
    • 15244342010 scopus 로고    scopus 로고
    • Matrix metalloproteinases as therapeutic targets in cancer
    • DOI 10.2174/1568009053765799
    • Vihinen P, Ala-aho R, Kahari VM (2005) Matrix metalloproteinases as therapeutic targets in cancer. Curr Cancer Drug Targets 5: 203-220. (Pubitemid 40694861)
    • (2005) Current Cancer Drug Targets , vol.5 , Issue.3 , pp. 203-220
    • Vihinen, P.1    Ala-Aho, R.2    Kahari, V.-M.3
  • 32
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • DOI 10.1038/35065000
    • Chang L, Karin M (2001) Mammalian MAP kinase signalling cascades. Nature 410: 37-40. (Pubitemid 32225829)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 33
    • 82955162775 scopus 로고    scopus 로고
    • Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways
    • Kannaiyan R, Manu KA, Chen L, Li F, Rajendran P, et al. (2011) Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways. Apoptosis 16: 1028-1041.
    • (2011) Apoptosis , vol.16 , pp. 1028-1041
    • Kannaiyan, R.1    Manu, K.A.2    Chen, L.3    Li, F.4    Rajendran, P.5
  • 34
    • 80052214870 scopus 로고    scopus 로고
    • Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation
    • Ben-Ami I, Yao Z, Naor Z, Seger R (2011) Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. J Biol Chem 286: 31022-31031.
    • (2011) J Biol Chem , vol.286 , pp. 31022-31031
    • Ben-Ami, I.1    Yao, Z.2    Naor, Z.3    Seger, R.4
  • 35
    • 79959765107 scopus 로고    scopus 로고
    • CXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activation
    • El-Haibi CP, Singh R, Sharma PK, Singh S, Lillard JW Jr (2011) CXCL13 mediates prostate cancer cell proliferation through JNK signalling and invasion through ERK activation. Cell Prolif 44: 311-319.
    • (2011) Cell Prolif , vol.44 , pp. 311-319
    • El-Haibi, C.P.1    Singh, R.2    Sharma, P.K.3    Singh, S.4    Lillard Jr., J.W.5
  • 36
    • 84866276473 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells
    • Bjorkblom B, Padzik A, Mohammad H, Westerlund N, Komulainen E, et al. (2012) c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells. Mol Cell Biol 32: 3513-3526.
    • (2012) Mol Cell Biol , vol.32 , pp. 3513-3526
    • Bjorkblom, B.1    Padzik, A.2    Mohammad, H.3    Westerlund, N.4    Komulainen, E.5
  • 37
    • 79955796236 scopus 로고    scopus 로고
    • Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways
    • Liu KC, Huang AC, Wu PP, Lin HY, Chueh FS, et al. (2011) Gallic acid suppresses the migration and invasion of PC-3 human prostate cancer cells via inhibition of matrix metalloproteinase-2 and -9 signaling pathways. Oncol Rep 26: 177-184.
    • (2011) Oncol Rep , vol.26 , pp. 177-184
    • Liu, K.C.1    Huang, A.C.2    Wu, P.P.3    Lin, H.Y.4    Chueh, F.S.5
  • 38
    • 77249096933 scopus 로고    scopus 로고
    • Expression of potential molecular markers in prostate cancer: Correlation with clinicopathological outcomes in patients undergoing radical prostatectomy
    • Miyake H, Muramaki M, Kurahashi T, Takenaka A, Fujisawa M (2010) Expression of potential molecular markers in prostate cancer: correlation with clinicopathological outcomes in patients undergoing radical prostatectomy. Urol Oncol 28: 145-151.
    • (2010) Urol Oncol , vol.28 , pp. 145-151
    • Miyake, H.1    Muramaki, M.2    Kurahashi, T.3    Takenaka, A.4    Fujisawa, M.5
  • 39
    • 4644237335 scopus 로고    scopus 로고
    • Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer
    • DOI 10.1158/0008-5472.CAN-03-3998
    • Rocchi P, So A, Kojima S, Signaevsky M, Beraldi E, et al. (2004) Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer. Cancer Res 64: 6595-6602. (Pubitemid 39297919)
    • (2004) Cancer Research , vol.64 , Issue.18 , pp. 6595-6602
    • Rocchi, P.1    So, A.2    Kojima, S.3    Signaevsky, M.4    Beraldi, E.5    Fazli, L.6    Hurtado-Coll, A.7    Yamanaka, K.8    Gleave, M.9
  • 40
    • 28244456529 scopus 로고    scopus 로고
    • Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis
    • DOI 10.1158/0008-5472.CAN-05-1840
    • Rocchi P, Beraldi E, Ettinger S, Fazli L, Vessella RL, et al. (2005) Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis. Cancer Res 65: 11083-11093. (Pubitemid 41713379)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 11083-11093
    • Rocchi, P.1    Beraldi, E.2    Ettinger, S.3    Fazli, L.4    Vessella, R.L.5    Nelson, C.6    Gleave, M.7
  • 42
    • 0027404982 scopus 로고
    • Type IV collagenase (M(r) 72,000) expression in human prostate: Benign and malignant tissue
    • Stearns ME, Wang M (1993) Type IV collagenase (M(r) 72,000) expression in human prostate: benign and malignant tissue. Cancer Res 53: 878-883. (Pubitemid 23077878)
    • (1993) Cancer Research , vol.53 , Issue.4 , pp. 878-883
    • Stearns, M.E.1    Wang, M.2
  • 43
    • 0029866005 scopus 로고    scopus 로고
    • Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression
    • Stearns M, Stearns ME (1996) Evidence for increased activated metalloproteinase 2 (MMP-2a) expression associated with human prostate cancer progression. Oncol Res 8: 69-75. (Pubitemid 26134926)
    • (1996) Oncology Research , vol.8 , Issue.2 , pp. 69-75
    • Stearns, M.1    Steams, M.E.2
  • 44
    • 0029928433 scopus 로고    scopus 로고
    • Immunohistochemical studies of activated matrix metalloproteinase-2 (MMP-2a)expression in human prostate cancer
    • Stearns ME, Stearns M (1996) Immunohistochemical studies of activated matrix metalloproteinase-2 (MMP-2a)expression in human prostate cancer. Oncol Res 8: 63-67.
    • (1996) Oncol Res , vol.8 , pp. 63-67
    • Stearns, M.E.1    Stearns, M.2
  • 45
    • 0030910423 scopus 로고    scopus 로고
    • In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer
    • DOI 10.1023/A:1018421431388
    • Wood M, Fudge K, Mohler JL, Frost AR, Garcia F, et al. (1997) In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer. Clin Exp Metastasis 15: 246-258. (Pubitemid 27240355)
    • (1997) Clinical and Experimental Metastasis , vol.15 , Issue.3 , pp. 246-258
    • Wood, M.1    Fudge, K.2    Mohler, J.L.3    Frost, A.R.4    Garcia, F.5    Wang, M.6    Stearns, M.E.7
  • 46
    • 84864911981 scopus 로고    scopus 로고
    • Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway
    • Liang H, Gu M, Yang C, Wang H, Wen X, et al. (2012) Sevoflurane inhibits invasion and migration of lung cancer cells by inactivating the p38 MAPK signaling pathway. J Anesth 26: 381-392.
    • (2012) J Anesth , vol.26 , pp. 381-392
    • Liang, H.1    Gu, M.2    Yang, C.3    Wang, H.4    Wen, X.5
  • 47
    • 73449134066 scopus 로고    scopus 로고
    • Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway
    • Shen KH, Hung SH, Yin LT, Huang CS, Chao CH, et al. (2010) Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway. Mol Cell Biochem 333: 279-291.
    • (2010) Mol Cell Biochem , vol.333 , pp. 279-291
    • Shen, K.H.1    Hung, S.H.2    Yin, L.T.3    Huang, C.S.4    Chao, C.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.