Polyclonal B cell activation for accurate analysis of pre-existing antigen-specific memory B cells

Clinical and Experimental Immunology

Volumn 177, Issue 1, 2014, Pages 333-340

  Karahan, G E ^a   Eikmans, M ^a   Anholts, J D H ^a   Claas, F H J ^a   Heidt, S ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Antibodies; Antibody secreting cells; B cells; ELISPOT

Indexed keywords

CD69 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 21; OLIGODEOXYNUCLEOTIDE;

ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL DEATH; COMPLEMENTARITY DETERMINING REGION; ENZYME LINKED IMMUNOSPOT ASSAY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; MEMORY CELL; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIBODIES; ANTIBODY-SECRETING CELLS; B CELLS; ELISPOT;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD40; B-LYMPHOCYTES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSPOT ASSAY; HUMANS; IMMUNOGLOBULIN G; IMMUNOLOGIC MEMORY; INTERLEUKINS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE SUBSETS; OLIGODEOXYRIBONUCLEOTIDES;

EID: 84904242647     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12305     Document Type: Article

References (37)

1. Kyu SY, Kobie J, Yang H etal. Frequencies of human influenza-specific antibody secreting cells or plasmablasts post vaccination from fresh and frozen peripheral blood mononuclear cells. J Immunol Methods 2009; 340:42-47.
2. Crotty S, Ahmed R. Immunological memory in humans. Semin Immunol 2004; 16:197-203.
3. Halliley JL, Kyu S, Kobie JJ etal. Peak frequencies of circulating human influenza-specific antibody secreting cells correlate with serum antibody response after immunization. Vaccine 2010; 28:3582-3587.
4. Weiss GE, Ndungu FM, McKittrick N etal. High efficiency human memory B cell assay and its application to studying Plasmodium falciparum-specific memory B cells in natural infections. J Immunol Methods 2012; 375:68-74.
5. Titanji K, De Milito A, Cagigi A etal. Loss of memory B cells impairs maintenance of long-term serologic memory during HIV-1 infection. Blood 2006; 108:1580-1587.
6. Ren S, Yu F, Zuo S etal. Inhibition of tumor angiogenesis in lung cancer by T4 phage surface displaying mVEGFR2 vaccine. Vaccine 2011; 29:5802-5811.
7. Tait BD, Susal C, Gebel HM etal. Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation. Transplantation 2013; 95:19-47.
8. Mulder A, Kardol MJ, Kamp J etal. Determination of the frequency of HLA antibody secreting B lymphocytes in alloantigen sensitized individuals. Clin Exp Immunol 2001; 124:9-15.
9. Zachary AA, Kopchaliiska D, Montgomery RA, Leffell MS. HLA-specific B cells: I. A method for their detection, quantification, and isolation using HLA tetramers. Transplantation 2007; 83:982-988.
10. Wadia PP, Herrera ND, Abecassis MM, Tambur AR. Mycophenolic acid inhibits maturation and function of human dendritic cells and B cells. Hum Immunol 2009; 70:692-700.
11. Heidt S, Roelen DL, de Vaal YJ etal. A novel ELISPOT assay to quantify HLA-specific B cells in HLA-immunized individuals. Am J Transplant 2012; 12:1469-1478.
12. Lynch RJ, Silva IA, Chen BJ, Punch JD, Cascalho M, Platt JL. Cryptic B cell response to renal transplantation. Am J Transplant 2013; 13:1713-1723.
13. Banchereau J, Rousset F. Growing human B lymphocytes in the CD40 system. Nature 1991; 353:678-679.
14. Rousset F, Garcia E, Banchereau J. Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen. J Exp Med 1991; 173:705-710.
15. Huggins J, Pellegrin T, Felgar RE etal. CpG DNA activation and plasma-cell differentiation of CD27- naive human B cells. Blood 2007; 109:1611-1619.
16. Giordani L, Sanchez M, Libri I, Quaranta MG, Mattioli B, Viora M. IFN-alpha amplifies human naive B cell TLR-9-mediated activation and Ig production. J Leukoc Biol 2009; 86:261-271.
17. Fecteau JF, Neron S. CD40 stimulation of human peripheral B lymphocytes: distinct response from naive and memory cells. J Immunol 2003; 171:4621-4629.
18. Ettinger R, Sims GP, Fairhurst AM etal. IL-21 induces differentiation of human naive and memory B cells into antibody-secreting plasma cells. J Immunol 2005; 175:7867-7879.
19. Nagumo H, Agematsu K, Kobayashi N etal. The different process of class switching and somatic hypermutation; a novel analysis by CD27(-) naive B cells. Blood 2002; 99:567-575.
20. Heidt S, Roelen DL, Eijsink C, van Kooten C, Claas FH, Mulder A. Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin. Transplantation 2008; 86:1292-1300.
21. Heidt S, Hester J, Shankar S, Friend PJ, Wood KJ. B-cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naive B cells. Am J Transplant 2012; 12:1784-1792.
22. Eikmans M, Rekers NV, Anholts JD, Heidt S, Claas FH. Blood cell mRNAs and microRNAs: optimized protocols for extraction and preservation. Blood 2013; 121:e81-89.
23. Silva HM, Takenaka MC, Moraes-Vieira PM etal. Preserving the B-cell compartment favors operational tolerance in human renal transplantation. Mol Med 2012; 18:733-743.
24. Lim A, Lemercier B, Wertz X, Pottier SL, Huetz F, Kourilsky P. Many human peripheral VH5-expressing IgM+ B cells display a unique heavy-chain rearrangement. Int Immunol 2008; 20:105-116.
25. Berek C, Berger A, Apel M. Maturation of the immune response in germinal centers. Cell 1991; 67:1121-1129.
26. Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R. SAP is required for generating long-term humoral immunity. Nature 2003; 421:282-287.
27. Manz RA, Arce S, Cassese G, Hauser AE, Hiepe F, Radbruch A. Humoral immunity and long-lived plasma cells. Curr Opin Immunol 2002; 14:517-521.
28. Bernasconi NL, Onai N, Lanzavecchia A. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 2003; 101:4500-4504.
29. Jiang W, Lederman MM, Harding CV, Rodriguez B, Mohner RJ, Sieg SF. TLR9 stimulation drives naive B cells to proliferate and to attain enhanced antigen presenting function. Eur J Immunol 2007; 37:2205-2213.
30. Eriksen AB, Indrevaer RL, Holm KL, Landskron J, Blomhoff HK. TLR9-signaling is required for turning retinoic acid into a potent stimulator of RP105 (CD180)-mediated proliferation and IgG synthesis in human memory B cells. Cell Immunol 2012; 279:87-95.
31. Tangye SG, Avery DT, Deenick EK, Hodgkin PD. Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses. J Immunol 2003; 170:686-694.
32. Ireland SJ, Blazek M, Harp CT etal. Antibody-independent B cell effector functions in relapsing remitting multiple sclerosis: clues to increased inflammatory and reduced regulatory B cell capacity. Autoimmunity 2012; 45:400-414.
33. Bernasconi NL, Traggiai E, Lanzavecchia A. Maintenance of serological memory by polyclonal activation of human memory B cells. Science 2002; 298:2199-2202.
34. Crotty S, Aubert RD, Glidewell J, Ahmed R. Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system. J Immunol Methods 2004; 286:111-122.
35. Han M, Rogers J, Lavingia B, Stastny P. Peripheral blood B cells producing donor-specific HLA antibodies in vitro. Hum Immunol 2009; 70:29-34.
36. Gupta S, Agrawal S, Gollapudi S. Increased activation and cytokine secretion in B cells stimulated with leptin in aged humans. Immun Ageing 2013; 10:3.
37. Kamburova EG, Koenen HJ, Boon L, Hilbrands LB, Joosten I. In vitro effects of rituximab on the proliferation, activation and differentiation of human B cells. Am J Transplant 2011; 12:341-350.