Methylenedioxy flavonoids: Assessment of cytotoxic and anti-cancer potential in human leukemia cells

European Journal of Medicinal Chemistry

Volumn 84, Issue , 2014, Pages 173-180

  Orlikova, Barbora ^a,b   Menezes, José C J M D S ^c,d   Ji, Seungwon ^a   Kamat, Shrivallabh P ^d   Cavaleiro, José A S ^c   Diederich, Marc ^a  

^a Seoul National University   (South Korea)

^b LABORATOIRE DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE DU CANCER   (Luxembourg)

^c UNIVERSITY OF AVEIRO   (Portugal)

^d GOA UNIVERSITY   (India)

Author keywords

Anti inflammatory; Chalcones; Cytotoxic; Flavanones; Flavones; Leukemia

Indexed keywords

2' HYDROXY 3',4' METHYLENEDIOXY 2 METHOXYCHALCONE; 2' HYDROXY 3',4' METHYLENEDIOXY 3,4,5 TRIMETHOXYCHALCONE; 3',4' DIMETHOXY 7,8 METHYLENEDIOXYFLAVANONE; 3',4' DIMETHOXY 7,8 METHYLENEDIOXYFLAVONE; 3,4 DIMETHOXY 2' HYDROXY 3',4' METHYLENEDIOXYCHALCONE; 7,8 METHYLENEDIOXY 2' METHOXYFLAVANONE; 7,8 METHYLENEDIOXY 2' METHOXYFLAVONE; 7,8 METHYLENEDIOXY 3',4',5' TRIMETHOXYFLAVANONE; 7,8 METHYLENEDIOXY 3',4',5' TRIMETHOXYFLAVONE; ANTINEOPLASTIC AGENT; BENZALDEHYDE DERIVATIVE; CASPASE; CHALCONE DERIVATIVE; FLAVONE DERIVATIVE; FLAVONOID; METHYLENEDIOXY FLAVONOID; UNCLASSIFIED DRUG; 7,8 METHYLENEDIOXY 3',4',4' TRIMETHOXYFLAVANONE; 7,8 METHYLENEDIOXY 3',4',4' TRIMETHOXYFLAVONE; ANTILEUKEMIC AGENT; APOPTOSIS INDUCING FACTOR; CYTOTOXIC AGENT; ETOPOSIDE; FLAVANONE DERIVATIVE; METHYLENEDIOXY FLAVONOID DERIVATIVE; CYTOTOXIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ANALYSIS; HUMAN; HUMAN CELL; JURKAT CELL LINE; K562 CELL LINE; LEUKEMIA CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; STRUCTURE ACTIVITY RELATION; U937 CELL LINE; ANTIPROLIFERATIVE ACTIVITY; CELL SPECIFICITY; DOWN REGULATION; PROTEIN CLEAVAGE; TARGET CELL; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; LEUKEMIA; PATHOLOGY; SYNTHESIS;

ANTINEOPLASTIC AGENTS; CELL DEATH; CELL PROLIFERATION; CELL SURVIVAL; CYTOTOXINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVONOIDS; HUMANS; JURKAT CELLS; K562 CELLS; LEUKEMIA; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; U937 CELLS;

EID: 84904209353     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.07.003     Document Type: Article

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