Integration of HIV-1 caused STAT3-associated B cell lymphoma in an AIDS patient

Microbes and Infection

Volumn 9, Issue 14-15, 2007, Pages 1581-1589

  Katano, Harutaka ^a   Sato, Yuko ^a   Hoshino, Satomi ^b   Tachikawa, Natsuo ^c   Oka, Shinichi ^c   Morishita, Yasuyuki ^d   Ishida, Takaomi ^e   Watanabe, Toshiki ^e   Rom, William N ^b   Mori, Shigeo ^f   Sata, Tetsutaro ^a   Weiden, Michael D ^b   Hoshino, Yoshihiko ^b  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

AIDS related lymphoma; HIV 1; Integration; STAT3

Indexed keywords

STAT3 PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; ARTICLE; B CELL LYMPHOMA; B LYMPHOCYTE; CASE REPORT; CELL NUCLEUS; CELL PROLIFERATION; CLINICAL FEATURE; EXON; FEVER; GENE DELETION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KAPOSI SARCOMA; LONG TERMINAL REPEAT; LYMPHOMA CELL; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SYMPTOM; UPREGULATION; VIRUS DNA CELL DNA INTERACTION;

BASE SEQUENCE; DNA, VIRAL; HIV-1; HUMANS; LYMPHOMA, AIDS-RELATED; LYMPHOMA, B-CELL; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PROVIRUSES; STAT3 TRANSCRIPTION FACTOR; VIRUS INTEGRATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 36749100011     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2007.09.008     Document Type: Article

References (30)

1. Carbone A. Emerging pathways in the development of AIDS-related lymphomas. Lancet Oncol. 4 (2003) 22-29
2. Boshoff C., and Weiss R. AIDS-related malignancies. Nat. Rev. Cancer 2 (2002) 373-382
3. Moore P.S., and Chang Y. Kaposi's Sarcoma-Associated Herpesvirus (2001), Lippincott Williams & Wilkins, Philadelphia
4. Chadburn A., Hyjek E., Mathew S., Cesarman E., Said J., and Knowles D.M. KSHV-positive solid lymphomas represent an extra-cavitary variant of primary effusion lymphoma. Am. J. Surg. Pathol. 28 (2004) 1401-1416
5. Hacein-Bey-Abina S., Von Kalle C., Schmidt M., McCormack M.P., Wulffraat N., Leboulch P., Lim A., Osborne C.S., Pawliuk R., Morillon E., Sorensen R., Forster A., Fraser P., Cohen J.I., de Saint Basile G., Alexander I., Wintergerst U., Frebourg T., Aurias A., Stoppa-Lyonnet D., Romana S., Radford-Weiss I., Gross F., Valensi F., Delabesse E., Macintyre E., Sigaux F., Soulier J., Leiva L.E., Wissler M., Prinz C., Rabbitts T.H., Le Deist F., Fischer A., and Cavazzana-Calvo M. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302 (2003) 415-419
6. Shiramizu B., Herndier B.G., and McGrath M.S. Identification of a common clonal human immunodeficiency virus integration site in human immunodeficiency virus-associated lymphomas. Cancer Res. 54 (1994) 2069-2072
7. Katano H., Sato Y., Kurata T., Mori S., and Sata T. Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease. Virology 269 (2000) 335-344
8. Katano H., Sato Y., Kurata T., Mori S., and Sata T. High expression of HHV-8-encoded ORF73 protein in spindle-shaped cells of Kaposi's sarcoma. Am. J. Pathol. 155 (1999) 47-52
9. Katano H., Hoshino Y., Morishita Y., Nakamura T., Satoh H., Iwamoto A., Herndier B., and Mori S. Establishing and characterizing a CD30-positive cell line harboring HHV-8 from a primary effusion lymphoma. J. Med. Virol. 58 (1999) 394-401
10. Katano H., Sato Y., and Sata T. Expression of p53 and human herpesvirus 8 (HHV-8)-encoded latency-associated nuclear antigen (LANA) with inhibition of apoptosis in HHV-8-associated malignancies. Cancer 92 (2001) 3076-3084
11. Asahi-Ozaki Y., Sato Y., Kanno T., Sata T., and Katano H. Quantitative analysis of Kaposi sarcoma-associated herpesvirus (KSHV) in KSHV-associated diseases. J. Infect. Dis. 193 (2006) 773-782
12. Koiwa T., Hamano-Usami A., Ishida T., Okayama A., Yamaguchi K., Kamihira S., and Watanabe T. 5′-long terminal repeat-selective CpG methylation of latent human T-cell leukemia virus type 1 provirus in vitro and in vivo. J. Virol. 76 (2002) 9389-9397
13. Hoshino Y., Nakata K., Hoshino S., Honda Y., Tse D.B., Shioda T., Rom W.N., and Weiden M. Maximal HIV-1 replication in alveolar macrophages during tuberculosis requires both lymphocyte contact and cytokines. J. Exp. Med. 195 (2002) 495-505
14. Katano H., Suda T., Morishita Y., Yamamoto K., Hoshino Y., Nakamura K., Tachikawa N., Sata T., Hamaguchi H., Iwamoto A., and Mori S. Human herpesvirus 8-associated solid lymphomas that occur in AIDS patients take anaplastic large cell morphology. Mod. Pathol. 13 (2000) 77-85
15. Hoshino Y., Tse D.B., Rochford G., Prabhakar S., Hoshino S., Chitkara N., Kuwabara K., Ching E., Raju B., Gold J.A., Borkowsky W., Rom W.N., Pine R., and Weiden M. Mycobacterium tuberculosis-induced CXCR4 and chemokine expression leads to preferential X4 HIV-1 replication in human macrophages. J. Immunol. 172 (2004) 6251-6258
16. Brown P.O., Bowerman B., Varmus H.E., and Bishop J.M. Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. Proc. Natl. Acad. Sci. USA 86 (1989) 2525-2529
17. Fujiwara T., and Mizuuchi K. Retroviral DNA integration: structure of an integration intermediate. Cell 54 (1988) 497-504
18. Hoshino Y., Hoshino S., Gold J.A., Raju B., Prabhakar S., Pine R., Rom W.N., Nakata K., and Weiden M. Mechanisms of PMN-mediated induction of HIV-1 replication in macrophages during pulmonary tuberculosis. J. Infect. Dis. (2007) 1303-1310
19. Bednarik D.P., Cook J.A., and Pitha P.M. Inactivation of the HIV LTR by DNA CpG methylation: evidence for a role in latency. Embo J 9 (1990) 1157-1164
20. Heinrich P.C., Behrmann I., Muller-Newen G., Schaper F., and Graeve L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334 Pt 2 (1998) 297-314
21. Bromberg J.F., Wrzeszczynska M.H., Devgan G., Zhao Y., Pestell R.G., Albanese C., and Darnell Jr. J.E. Stat3 as an oncogene. Cell 98 (1999) 295-303
22. Catlett-Falcone R., Dalton W.S., and Jove R. STAT proteins as novel targets for cancer therapy. Signal transducer an activator of transcription. Curr. Opin. Oncol. 11 (1999) 490-496
23. Lin T.S., Mahajan S., and Frank D.A. STAT signaling in the pathogenesis and treatment of leukemias. Oncogene 19 (2000) 2496-2504
24. Yang J., Chatterjee-Kishore M., Staugaitis S.M., Nguyen H., Schlessinger K., Levy D.E., and Stark G.R. Novel roles of unphosphorylated STAT3 in oncogenesis and transcriptional regulation. Cancer Res. 65 (2005) 939-947
25. Nelson K.L., Rogers J.A., Bowman T.L., Jove R., and Smithgall T.E. Activation of STAT3 by the c-Fes protein-tyrosine kinase. J. Biol. Chem. 273 (1998) 7072-7077
26. Pelicci P.G., Knowles II D.M., Arlin Z.A., Wieczorek R., Luciw P., Dina D., Basilico C., and Dalla-Favera R. Multiple monoclonal B cell expansions and c-myc oncogene rearrangements in acquired immune deficiency syndrome-related lymphoproliferative disorders. Implications for lymphomagenesis. J. Exp. Med. 164 (1986) 2049-2060
27. Merat R., Amara A., Lebbe C., de The H., Morel P., and Saib A. HIV-1 infection of primary effusion lymphoma cell line triggers Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation. Int. J. Cancer 97 (2002) 791-795
28. Caselli E., Galvan M., Santoni F., Rotola A., Caruso A., Cassai E., and Luca D.D. Human herpesvirus-8 (Kaposi's sarcoma-associated virus) ORF50 increases in vitro cell susceptibility to human immunodeficiency virus type 1 infection. J. Gen. Virol. 84 (2003) 1123-1131
29. Schroder A.R., Shinn P., Chen H., Berry C., Ecker J.R., and Bushman F. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110 (2002) 521-529
30. Hishima T., Oyaizu N., Fujii T., Tachikawa N., Ajisawa A., Negishi M., Nakamura T., Iwamoto A., Hayashi Y., Matsubara D., Sasao Y., Kimura S., Kikuchi Y., Teruya K., Yasuoka A., Oka S., Saito K., Mori S., Funata N., Sata T., and Katano H. Decrease in Epstein-Barr virus-positive AIDS-related lymphoma in the era of highly active antiretroviral therapy. Microbes Infect. 8 (2006) 1301-1307