MR imaging-detectable metabolic alterations in attention deficit/hyperactivity disorder: From preclinical to clinical studies

American Journal of Neuroradiology

Volumn 35, Issue 6 SUPPL., 2014, Pages

  Altabella, L ^a   Zoratto, F ^a,b   Adriani, W ^a   Canese, Rossella ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; CREATINE; DOPAMINE TRANSPORTER; GLUTAMIC ACID; METHYLPHENIDATE;

ADULTHOOD; ATTENTION DEFICIT DISORDER; BRAIN REGION; CEREBELLUM; CEREBELLUM VERMIS; CHILDHOOD; CORPUS CALLOSUM; CORPUS STRIATUM; FRONTAL CORTEX; HIPPOCAMPUS; HUMAN; META ANALYSIS (TOPIC); METABOLIC DISORDER; NEUROBIOLOGY; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOPHYSIOLOGY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; POSTERIOR CINGULATE; PREFRONTAL CORTEX; REVIEW; THALAMUS; ANIMAL; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN; DISEASE MODEL; METABOLISM; PROCEDURES; RODENT;

ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; RODENTIA;

EID: 84904093061     PISSN: 01956108     EISSN: 1936959X     Source Type: Journal    
DOI: 10.3174/ajnr.A3843     Document Type: Review

References (64)

1. Oades RD. Frontal, temporal and lateralized brain function in children with attention-deficit hyperactivity disorder: a psychophysiological and neuropsychological viewpoint on development. Behav Brain Res 1998;94:83-95 (Pubitemid 28352467)
2. Castellanos FX, Sonuga-Barke EJ, Milham MP, et al. Characterizing cognition in ADHD: beyond executive dysfunction. Trends Cogn Sci 2006;10:117-23
3. Sonuga-Barke EJ. Causal models of attention-deficit/hyperactivity disorder: from common simple deficits to multiple developmental pathways. Biol Psychiatry 2005;57:1231-38 (Pubitemid 40798540)
4. Casey BJ, Durston S. From behavior to cognition to the brain and back: what have we learned from functional imaging studies of attention deficit hyperactivity disorder? Am J Psychiatry 2006;163:957-60 (Pubitemid 44464479)
5. Sagvolden T, Aase H, Zeiner P, et al. Altered reinforcement mechanisms in attention-deficit/hyperactivity disorder. Behav Brain Res 1998;94:61-71 (Pubitemid 28352465)
6. Accardo P, Blondis TA. What's all the fuss about Ritalin? J Pediatr 2001;138:6-9 (Pubitemid 32097134)
7. Scheffler RM, Hinshaw SP, Modrek S, et al. The global market for ADHD medications. Health Aff (Millwood) 2007;26:450-57
8. Altabella L, Strolin S, Villani N, et al. Magnetic resonance imaging and spectroscopy in the study in ADHD syndrome: a short review. Biophysics and Bioeng Letters 2011;4:23-34
9. Bush G. Cingulate, frontal, and parietal cortical dysfunction in attention-deficit/hyperactivity disorder. Biol Psychiatry 2011;69:1160-67
10. Hart H, Radua J, Mataix-Cols D, et al. Meta-analysis of fMRI studies of timing in attention-deficit hyperactivity disorder (ADHD). Neurosci Biobehav Rev 2012;36:2248-56
11. de Graaf RA. In Vivo NMR Spectroscopy: Principles and Techniques. Chichester, UK: John Wiley; 2008
12. Posse S, Otazo R, Dager SR, et al. MR spectroscopic imaging: principles and recent advances. J Magn Reson Imaging 2013;37:1301-25
13. Canese R, Pisanu ME, Mezzanzanica D, et al. Characterisation of in vivo ovarian cancer models by quantitative 1H magnetic resonance spectroscopy and diffusion-weighted imaging. NMR Biomed 2012;25:632-42
14. Scheidegger O, Wingeier K, Stefan D, et al. Optimized quantitative magnetic resonance spectroscopy for clinical routine. Magn Reson Med 2013;70:25-32
15. Puts NA, Edden RA. In vivo magnetic resonance spectroscopy of GABA: a methodological review. Prog Nucl Magn Reson Spectrosc 2012;60:29-41
16. Blüml S, Wisnowski JL, NelsonMDJr, et al. Metabolic maturation of the human brain from birth through adolescence: insights from in vivo magnetic resonance spectroscopy. Cereb Cortex 2013;23:2944-55
17. Horská A, Kaufmann WE, Brant LJ, et al. In vivo quantitative proton MRSI study of brain development from childhood to adolescence. J Magn Reson Imaging 2002;15:137-43 (Pubitemid 34112902)
18. Vyas NS, Patel NH, Herscovitch P, et al. Recent developments in neurochemical imaging in schizophrenia: an update. Curr Med Chem 2013;20:351-56
19. Kraguljac NV, Reid M, White D, et al. Neurometabolites in schizophrenia and bipolar disorder: a systematic review and meta-analysis. Psychiatry Res 2012;203:111-25
20. Baruth JM, Wall CA, Patterson MC, et al. Proton magnetic resonance spectroscopy as a probe into the pathophysiology of autism spectrum disorders (ASD): a review. Autism Res 2013;6:119-33
21. Biederman J, Faraone SV. Attention-deficit hyperactivity disorder. Lancet 2005;366:237-48 (Pubitemid 40981053)
22. van der Staay FJ. Animal models of behavioral dysfunctions: basic concepts and classifications, and an evaluation strategy. Brain Res Rev 2006;52:131-59 (Pubitemid 44069577)
23. Shaywitz BA, Yager RD, Klopper JH. Selective brain dopamine depletion in developing rats: an experimental model of minimal brain dysfunction. Science 1976;191:305-08
24. Fan X, Bruno KJ, Hess EJ. Rodent models of ADHD. Curr Top Behav Neurosci 2012;9:273-300
25. Adriani W, Boyer F, Gioiosa L, et al. Increased impulsive behavior and risk proneness following lentivirus-mediated dopamine transporter over-expression in rats' nucleus accumbens. Neuroscience 2009;159:47-58
26. Adriani W, Boyer F, Leo D, et al. Social withdrawal and gambling-like profile after lentiviral manipulation of DAT expression in the rat accumbens. Int J Neuropsychopharmacol 2010;13:1329-42
27. Adriani W, Zoratto F, Laviola G. Brain processes in discounting: consequences of adolescent methylphenidate exposure. Curr Top Behav Neurosci 2012;9:113-43
28. Adriani W, Canese R, Podo F, et al. 1H MRS-detectable metabolic brain changes and reduced impulsive behavior in adult rats exposed to methylphenidate during adolescence. Neurotoxicol Teratol 2007;29:116-25 (Pubitemid 46205168)
29. Adriani W, Leo D, Greco D, et al. Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression. Neuropsychopharmacology 2006; 31:1946-56
30. Perlov E, Philipsen A, Matthies S, et al. Spectroscopic findings in attention-deficit/hyperactivity disorder: review and meta-analysis. World J Biol Psychiatry 2009;10:355-65
31. Hammerness P, Biederman J, Petty C, et al. Brain biochemical effects of methylphenidate treatment using proton magnetic spectroscopy in youth with attention-deficit hyperactivity disorder: a controlled pilot study. CNS Neurosci Ther 2012;18:34-40
32. Arcos-Burgos M, Londono AC, Pineda DA, et al. Analysis of brain metabolism by proton magnetic resonance spectroscopy (1H-MRS) in attention-deficit/hyperactivity disorder suggests a generalized differential ontogenic pattern from controls. Atten Defic Hyperact Disord 2012;4:205-12
33. Krain AL, Castellanos FX. Brain development and ADHD. Clin Psychol Rev 2006;26:433-44
34. Tafazoli S, O'Neill J, Bejjani A, et al. 1H MRSI of middle frontal gyrus in pediatric ADHD. J Psychiatr Res 2013;47:505-12
35. Soliva JC, Moreno A, Fauquet J, et al. Cerebellar neurometabolite abnormalities in pediatric attention/deficit hyperactivity disorder: a proton MR spectroscopic study. Neurosci Lett 2010;470:60-64
36. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30: 672-79 (Pubitemid 23360802)
37. Provencher SW. Automatic quantitation of localized in vivo 1H spectra with LCModel. NMR Biomed 2001;14:260-64 (Pubitemid 32611437)
38. Carrey NJ, MacMaster FP, Gaudet L, et al. Striatal creatine and glutamate/glutamine in attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol 2007;17:11-17 (Pubitemid 46452078)
39. Yang P, Wu MT, Dung SS, et al. Short-TE proton magnetic resonance spectroscopy investigation in adolescents with attention-deficit hyperactivity disorder. Psychiatry Res 2010;181:199-203
40. Hesslinger B, Thiel T, Tebartz van Elst L, et al. Attention-deficit disorder in adults with or without hyperactivity: where is the difference? Astudy inhumansusing short echo (1)H-magnetic resonance spectroscopy. Neurosci Lett 2001;304:117-19 (Pubitemid 32373328)
41. Edden RA, Crocetti D, Zhu H, et al. Reduced GABA concentration in attention-deficit/hyperactivity disorder. Arch Gen Psychiatry 2012;69:750-53
42. Stanley JA, Kipp H, Greisenegger E, et al. Evidence of developmental alterations in cortical and subcortical regions of children with attention-deficit/hyperactivity disorder: a multivoxel in vivo phosphorus 31 spectroscopy study. Arch Gen Psychiatry 2008;65:1419-28
43. Stanley JA, Kipp H, Greisenegger E, et al. Regionally specific alterations in membrane phospholipids in children with ADHD: an in vivo 31P spectroscopy study. Psychiatry Res 2006;148:217-21 (Pubitemid 44750591)
44. Colla M, Ende G, Alm B, et al. Cognitive MR spectroscopy of anterior cingulate cortex in ADHD: elevated choline signal correlates with slowed hit reaction times. J Psychiatr Res 2008;42:587-95 (Pubitemid 351400485)
45. Perlov E, Philipsen A, Hesslinger B, et al. Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder: a magnet resonance spectroscopy study. J Psychiatr Res 2007;41:934-41 (Pubitemid 47259094)
46. Dramsdahl M, Ersland L, Plessen KJ, et al. Adults with attention-deficit/hyperactivity disorder: a brain magnetic resonance spectroscopy study. Front Psychiatry 2011;2:65
47. Kronenberg G, Ende G, Alm B, et al. Increased NAA and reduced choline levels in the anterior cingulum following chronic methylphenidate: a spectroscopic test-retest study in adult ADHD. Eur Arch Psychiatry Clin Neurosci 2008;258:446-50
48. Perlov E, Tebarzt van Elst L, Buechert M, et al. H(1)-MR-spectroscopy of cerebellum in adult attention deficit/hyperactivity disorder. J Psychiatr Res 2010;44:938-43
49. Yin HH, Knowlton BJ, Balleine BW. Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning. Eur J Neurosci 2004;19:181-89 (Pubitemid 38122084)
50. Cardinal RN, Winstanley CA, Robbins TW, et al. Limbic corticostriatal systems and delayed reinforcement. Ann N Y Acad Sci 2004;1021:33-50 (Pubitemid 38879608)
51. Bjork JM, Knutson B, Fong GW, et al. Incentive-elicited brain activation in adolescents: similarities and differences from young adults. J Neurosci 2004;24:1793-802 (Pubitemid 38292790)
52. Dalley JW, Cardinal RN, Robbins TW. Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates. Neurosci Biobehav Rev 2004;28:771-84 (Pubitemid 39535871)
53. Arnsten AF. Toward a new understanding of attention-deficit hyperactivity disorder pathophysiology: an important role for prefrontal cortex dysfunction. CNS Drugs 2009;23(suppl 1):33-41
54. Seamans JK, Lapish CC, Durstewitz D. Comparing the prefrontal cortex of rats and primates: insights from electrophysiology. Neurotox Res 2008;14:249-62
55. Ridderinkhof KR, van den Wildenberg WP, Segalowitz SJ, et al. Neurocognitive mechanisms of cognitive control: the role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning. Brain Cogn 2004;56:129 - 40
56. Frodl T, Skokauskas N. Meta-analysis of structural MRI studies in children and adults with attention deficit hyperactivity disorder indicates treatment effects. Acta Psychiatr Scand 2012;125:114 -26
57. Hoerst M, Weber-Fahr W, Tunc-Skarka N, et al. Correlation of glutamate levels in the anterior cingulate cortex with self-reported impulsivity in patients with borderline personality disorder and healthy controls. Arch Gen Psychiatry 2010;67:946-54
58. Carlsson ML. On the role of prefrontal cortex glutamate for the antithetical phenomenology of obsessive compulsive disorder and attention deficit hyperactivity disorder. Prog Neuropsychopharmacol Biol Psychiatry 2001;25:5-26 (Pubitemid 32173787)
59. Todd RD, Botteron KN. Is attention-deficit/hyperactivity disorder an energy deficiency syndrome? Biol Psychiatry 2001;50:151-58 (Pubitemid 32763092)
60. Silveri MM, Sneider JT, Crowley DJ, et al. Frontal lobe gamma-aminobutyric acid levels during adolescence: associations with impulsivity and response inhibition. Biol Psychiatry 2013;74:296 -304
61. Dautry C, Vaufrey F, Brouillet E, et al. Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid. J Cereb Blood Flow Metab 2000;20:789-99 (Pubitemid 30317053)
62. Fagundes AO, Rezin GT, Zanette F, et al. Chronic administration of methylphenidate activates mitochondrial respiratory chain in brain of young rats. Int J Dev Neurosci 2007;25:47-51 (Pubitemid 46162062)
63. De Stefano N, Filippi M. MR spectroscopy in multiple sclerosis. J Neuroimaging 2007;17(suppl 1):31S-35S (Pubitemid 46558266)
64. Gujar SK, Maheshwari S, Bjorkman-Burtscher I, et al. Magnetic resonance spectroscopy. J Neuroophthalmol 2005;25:217-26 (Pubitemid 41306683)