MOG extracellular domain (p1-125) triggers elevated frequency of CXCR3+ CD4+ Th1 cells in the CNS of mice and induces greater incidence of severe EAE

Multiple Sclerosis

Volumn 20, Issue 10, 2014, Pages 1312-1321

  Mony, Jyothi T ^a   Khorooshi, Reza ^a   Owens, Trevor ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Central nervous system; Chemokine receptors; Cytokines; Experimental autoimmune encephalomyelitis; Immunogen; Inflammation; Interferon gamma; Mouse study; Myelin oligodendrocyte glycoprotein; T cells

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR3; CYTOKINE; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 17; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN IMMUNOGLOBULIN LIKE DOMAIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN P35-55; UNCLASSIFIED DRUG; CXCR3 PROTEIN, MOUSE; MOG PROTEIN, RAT; MYELIN OLIGODENDROCYTE GLYCOPROTEIN (1-125); MYELIN OLIGODENDROCYTE GLYCOPROTEIN (35-55); PEPTIDE FRAGMENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CD4 LYMPHOCYTE PERCENTAGE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE SEVERITY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; EXTRACELLULAR SPACE; FEMALE; FLOW CYTOMETRY; IMMUNOPATHOGENESIS; INCIDENCE; INTERFERON PRODUCTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NEUROPATHOLOGY; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; SPINAL CORD; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; TH17 CELL; TIME; UPREGULATION; ANIMAL; C57BL MOUSE; CENTRAL NERVOUS SYSTEM; COMPARATIVE STUDY; IMMUNIZATION; IMMUNOLOGY; METABOLISM; RAT; SEVERITY OF ILLNESS INDEX;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; DISEASE PROGRESSION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; EPITOPES; FEMALE; IMMUNIZATION; INTERFERON-GAMMA; MICE, INBRED C57BL; MYELIN-OLIGODENDROCYTE GLYCOPROTEIN; PEPTIDE FRAGMENTS; RATS; RECEPTORS, CXCR3; SEVERITY OF ILLNESS INDEX; TH1 CELLS; TH17 CELLS; TIME FACTORS;

EID: 84904054652     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458514524086     Document Type: Article

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