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Volumn 9, Issue 1, 2012, Pages

Active induction of experimental autoimmune encephalomyelitis by MOG 35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus

Author keywords

Choroid plexus; EAE; Laser capture microdissection (LCM); Neuroinflammation; Pertussis toxin

Indexed keywords

FREUND ADJUVANT; MYELIN OLIGODENDROCYTE GLYCOPROTEIN PEPTIDE; PEPTIDE VACCINE; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

EID: 84868712401     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-9-15     Document Type: Article
Times cited : (40)

References (76)
  • 1
    • 0014812865 scopus 로고
    • The effects of some inhibitors and accelerators of sodium transport on the turnover of 22Na in the cerebrospinal fluid and the brain
    • 1396036, 5499038
    • Davson H, Segal MB. The effects of some inhibitors and accelerators of sodium transport on the turnover of 22Na in the cerebrospinal fluid and the brain. J Physiol 1970, 209:131-153. 1396036, 5499038.
    • (1970) J Physiol , vol.209 , pp. 131-153
    • Davson, H.1    Segal, M.B.2
  • 2
    • 0035156659 scopus 로고    scopus 로고
    • Mechanisms of CSF secretion by the choroid plexus
    • 10.1002/1097-0029(20010101)52:1<49::AID-JEMT7>3.0.CO;2-C, 11135448
    • Speake T, Whitwell C, Kajita H, Majid A, Brown PD. Mechanisms of CSF secretion by the choroid plexus. Microsc Res Tech 2001, 52:49-59. 10.1002/1097-0029(20010101)52:1<49::AID-JEMT7>3.0.CO;2-C, 11135448.
    • (2001) Microsc Res Tech , vol.52 , pp. 49-59
    • Speake, T.1    Whitwell, C.2    Kajita, H.3    Majid, A.4    Brown, P.D.5
  • 3
    • 9344226762 scopus 로고    scopus 로고
    • Molecular mechanisms of cerebrospinal fluid production
    • 1890044, 15561411
    • Brown PD, Davies SL, Speake T, Millar ID. Molecular mechanisms of cerebrospinal fluid production. Neuroscience 2004, 129:957-970. 1890044, 15561411.
    • (2004) Neuroscience , vol.129 , pp. 957-970
    • Brown, P.D.1    Davies, S.L.2    Speake, T.3    Millar, I.D.4
  • 4
    • 0035153262 scopus 로고    scopus 로고
    • Involvement of the choroid plexus in central nervous system inflammation
    • 10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5, 11135454
    • Engelhardt B, Wolburg-Buchholz K, Wolburg H. Involvement of the choroid plexus in central nervous system inflammation. Microsc Res Tech 2001, 52:112-129. 10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5, 11135454.
    • (2001) Microsc Res Tech , vol.52 , pp. 112-129
    • Engelhardt, B.1    Wolburg-Buchholz, K.2    Wolburg, H.3
  • 5
    • 34247108119 scopus 로고    scopus 로고
    • Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis
    • 10.1002/cne.21307, 17348011
    • Brown DA, Sawchenko PE. Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis. J Comp Neurol 2007, 502:236-260. 10.1002/cne.21307, 17348011.
    • (2007) J Comp Neurol , vol.502 , pp. 236-260
    • Brown, D.A.1    Sawchenko, P.E.2
  • 9
    • 65649096159 scopus 로고    scopus 로고
    • Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis
    • 10.1002/ana.21379, 3305810, 18496841
    • Kivisakk P, Imitola J, Rasmussen S, Elyaman W, Zhu B, Ransohoff RM, Khoury SJ. Localizing central nervous system immune surveillance: meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis. Ann Neurol 2009, 65:457-469. 10.1002/ana.21379, 3305810, 18496841.
    • (2009) Ann Neurol , vol.65 , pp. 457-469
    • Kivisakk, P.1    Imitola, J.2    Rasmussen, S.3    Elyaman, W.4    Zhu, B.5    Ransohoff, R.M.6    Khoury, S.J.7
  • 11
    • 67349216357 scopus 로고    scopus 로고
    • Autoimmune T cell responses in the central nervous system
    • 10.1038/nri2550, 2813731, 19444307
    • Goverman J. Autoimmune T cell responses in the central nervous system. Nat Rev Immunol 2009, 9:393-407. 10.1038/nri2550, 2813731, 19444307.
    • (2009) Nat Rev Immunol , vol.9 , pp. 393-407
    • Goverman, J.1
  • 12
    • 77649192491 scopus 로고    scopus 로고
    • Choroid plexus: biology and pathology
    • 10.1007/s00401-009-0627-8, 20033190
    • Wolburg H, Paulus W. Choroid plexus: biology and pathology. Acta Neuropathol 2010, 119:75-88. 10.1007/s00401-009-0627-8, 20033190.
    • (2010) Acta Neuropathol , vol.119 , pp. 75-88
    • Wolburg, H.1    Paulus, W.2
  • 13
    • 0002645997 scopus 로고
    • Ultrastructural characteristics of adult choroid plexus: Relation to the blood-cerebral spinal fluid barrier to proteins
    • University Press of Virginia Charlottesville, VA, Netsky MG
    • Brightman M. Ultrastructural characteristics of adult choroid plexus: Relation to the blood-cerebral spinal fluid barrier to proteins. The Choroid Plexus in Health and Disease 1975, 86-112. University Press of Virginia Charlottesville, VA, Netsky MG.
    • (1975) The Choroid Plexus in Health and Disease , pp. 86-112
    • Brightman, M.1
  • 14
    • 0019491309 scopus 로고
    • The fate of plasma protein which escapes from blood vessels of the choroid plexus of the rat-an electron microscope study
    • 10.1002/path.1711340107, 7288528
    • Hurley JV, Anderson RM, Sexton PT. The fate of plasma protein which escapes from blood vessels of the choroid plexus of the rat-an electron microscope study. J Pathol 1981, 134:57-70. 10.1002/path.1711340107, 7288528.
    • (1981) J Pathol , vol.134 , pp. 57-70
    • Hurley, J.V.1    Anderson, R.M.2    Sexton, P.T.3
  • 15
    • 4644265281 scopus 로고    scopus 로고
    • The structure of the choroid plexus and the physiology of the choroid plexus epithelium
    • 10.1016/j.addr.2004.07.005, 15381330
    • Redzic ZB, Segal MB. The structure of the choroid plexus and the physiology of the choroid plexus epithelium. Adv Drug Deliv Rev 2004, 56:1695-1716. 10.1016/j.addr.2004.07.005, 15381330.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1695-1716
    • Redzic, Z.B.1    Segal, M.B.2
  • 16
    • 79951682931 scopus 로고    scopus 로고
    • The blood-cerebrospinal fluid barrier: structure and functional significance
    • 10.1007/978-1-60761-938-3_4, 21082368
    • Johanson CE, Stopa EG, McMillan PN. The blood-cerebrospinal fluid barrier: structure and functional significance. Methods Mol Biol 2011, 686:101-131. 10.1007/978-1-60761-938-3_4, 21082368.
    • (2011) Methods Mol Biol , vol.686 , pp. 101-131
    • Johanson, C.E.1    Stopa, E.G.2    McMillan, P.N.3
  • 17
    • 65249141706 scopus 로고    scopus 로고
    • Gaining entry to an uninflamed brain
    • 10.1038/ni0509-453, 19381137
    • Axtell RC, Steinman L. Gaining entry to an uninflamed brain. Nat Immunol 2009, 10:453-455. 10.1038/ni0509-453, 19381137.
    • (2009) Nat Immunol , vol.10 , pp. 453-455
    • Axtell, R.C.1    Steinman, L.2
  • 18
    • 70449102882 scopus 로고    scopus 로고
    • Immunology: In the beginning
    • 10.1038/462041a, 19890316
    • Ransohoff RM. Immunology: In the beginning. Nature 2009, 462:41-42. 10.1038/462041a, 19890316.
    • (2009) Nature , vol.462 , pp. 41-42
    • Ransohoff, R.M.1
  • 19
    • 0029952623 scopus 로고    scopus 로고
    • ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro
    • 1861637, 8669469
    • Steffen BJ, Breier G, Butcher EC, Schulz M, Engelhardt B. ICAM-1, VCAM-1, and MAdCAM-1 are expressed on choroid plexus epithelium but not endothelium and mediate binding of lymphocytes in vitro. Am J Pathol 1996, 148:1819-1838. 1861637, 8669469.
    • (1996) Am J Pathol , vol.148 , pp. 1819-1838
    • Steffen, B.J.1    Breier, G.2    Butcher, E.C.3    Schulz, M.4    Engelhardt, B.5
  • 20
    • 0037867698 scopus 로고    scopus 로고
    • Ultrastructural localization of adhesion molecules in the healthy and inflamed choroid plexus of the mouse
    • 10.1007/s004410051287, 10382270
    • Wolburg K, Gerhardt H, Schulz M, Wolburg H, Engelhardt B. Ultrastructural localization of adhesion molecules in the healthy and inflamed choroid plexus of the mouse. Cell Tissue Res 1999, 296:259-269. 10.1007/s004410051287, 10382270.
    • (1999) Cell Tissue Res , vol.296 , pp. 259-269
    • Wolburg, K.1    Gerhardt, H.2    Schulz, M.3    Wolburg, H.4    Engelhardt, B.5
  • 23
    • 84859091097 scopus 로고    scopus 로고
    • Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan((R)) Low Density Array
    • 10.1016/j.jneumeth.2012.02.023, 22425714
    • Demarest TG, Murugesan N, Shrestha B, Pachter JS. Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan((R)) Low Density Array. J Neurosci Methods 2012, 206:200-204. 10.1016/j.jneumeth.2012.02.023, 22425714.
    • (2012) J Neurosci Methods , vol.206 , pp. 200-204
    • Demarest, T.G.1    Murugesan, N.2    Shrestha, B.3    Pachter, J.S.4
  • 24
    • 50949109478 scopus 로고    scopus 로고
    • Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood-brain barrier gene expression in situ
    • 10.1016/j.jneumeth.2008.07.009, 18692089
    • Macdonald JA, Murugesan N, Pachter JS. Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood-brain barrier gene expression in situ. J Neurosci Methods 2008, 174:219-226. 10.1016/j.jneumeth.2008.07.009, 18692089.
    • (2008) J Neurosci Methods , vol.174 , pp. 219-226
    • Macdonald, J.A.1    Murugesan, N.2    Pachter, J.S.3
  • 25
    • 0033961796 scopus 로고    scopus 로고
    • Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis
    • Juedes AE, Hjelmstrom P, Bergman CM, Neild AL, Ruddle NH. Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. J Immunol 2000, 164:419-426.
    • (2000) J Immunol , vol.164 , pp. 419-426
    • Juedes, A.E.1    Hjelmstrom, P.2    Bergman, C.M.3    Neild, A.L.4    Ruddle, N.H.5
  • 26
    • 28844455058 scopus 로고    scopus 로고
    • Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection
    • 10.1016/j.brainresprot.2005.08.002, 16168706
    • Kinnecom K, Pachter JS. Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection. Brain Res Brain Res Protoc 2005, 16:1-9. 10.1016/j.brainresprot.2005.08.002, 16168706.
    • (2005) Brain Res Brain Res Protoc , vol.16 , pp. 1-9
    • Kinnecom, K.1    Pachter, J.S.2
  • 27
    • 77952035085 scopus 로고    scopus 로고
    • Endothelial cell heterogeneity of blood-brain barrier gene expression along the cerebral microvasculature
    • Macdonald JA, Murugesan N, Pachter JS. Endothelial cell heterogeneity of blood-brain barrier gene expression along the cerebral microvasculature. J Neurosci Res 2010, 88:1457-1474.
    • (2010) J Neurosci Res , vol.88 , pp. 1457-1474
    • Macdonald, J.A.1    Murugesan, N.2    Pachter, J.S.3
  • 28
    • 79955864356 scopus 로고    scopus 로고
    • Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics
    • 10.1007/978-1-60761-938-3_14, 21082378
    • Murugesan N, Macdonald JA, Lu Q, Wu SL, Hancock WS, Pachter JS. Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics. Methods Mol Biol 2011, 686:297-311. 10.1007/978-1-60761-938-3_14, 21082378.
    • (2011) Methods Mol Biol , vol.686 , pp. 297-311
    • Murugesan, N.1    Macdonald, J.A.2    Lu, Q.3    Wu, S.L.4    Hancock, W.S.5    Pachter, J.S.6
  • 30
    • 79961160742 scopus 로고    scopus 로고
    • Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
    • 10.1084/jem.20102657, 3149213, 21788405
    • Anandasabapathy N, Victora GD, Meredith M, Feder R, Dong B, Kluger C, Yao K, Dustin ML, Nussenzweig MC, Steinman RM, Liu K. Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain. J Exp Med 2011, 208:1695-1705. 10.1084/jem.20102657, 3149213, 21788405.
    • (2011) J Exp Med , vol.208 , pp. 1695-1705
    • Anandasabapathy, N.1    Victora, G.D.2    Meredith, M.3    Feder, R.4    Dong, B.5    Kluger, C.6    Yao, K.7    Dustin, M.L.8    Nussenzweig, M.C.9    Steinman, R.M.10    Liu, K.11
  • 31
    • 33645087923 scopus 로고    scopus 로고
    • Molecular mechanisms involved in T cell migration across the blood-brain barrier
    • 10.1007/s00702-005-0409-y, 16550326
    • Engelhardt B. Molecular mechanisms involved in T cell migration across the blood-brain barrier. J Neural Transm 2006, 113:477-485. 10.1007/s00702-005-0409-y, 16550326.
    • (2006) J Neural Transm , vol.113 , pp. 477-485
    • Engelhardt, B.1
  • 32
    • 17044372405 scopus 로고    scopus 로고
    • CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study
    • 10.1016/j.jneuroim.2005.01.020, 15833367
    • dos Santos AC, Barsante MM, Arantes RM, Bernard CC, Teixeira MM, Carvalho-Tavares J. CCL2 and CCL5 mediate leukocyte adhesion in experimental autoimmune encephalomyelitis-an intravital microscopy study. J Neuroimmunol 2005, 162:122-129. 10.1016/j.jneuroim.2005.01.020, 15833367.
    • (2005) J Neuroimmunol , vol.162 , pp. 122-129
    • dos Santos, A.C.1    Barsante, M.M.2    Arantes, R.M.3    Bernard, C.C.4    Teixeira, M.M.5    Carvalho-Tavares, J.6
  • 33
    • 13844275122 scopus 로고    scopus 로고
    • Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes
    • 10.1016/j.brainres.2004.12.017, 15722060
    • Moon C, Ahn M, Wie MB, Kim HM, Koh CS, Hong SC, Kim MD, Tanuma N, Matsumoto Y, Shin T. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res 2005, 1035:206-210. 10.1016/j.brainres.2004.12.017, 15722060.
    • (2005) Brain Res , vol.1035 , pp. 206-210
    • Moon, C.1    Ahn, M.2    Wie, M.B.3    Kim, H.M.4    Koh, C.S.5    Hong, S.C.6    Kim, M.D.7    Tanuma, N.8    Matsumoto, Y.9    Shin, T.10
  • 34
    • 77957358322 scopus 로고    scopus 로고
    • Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated
    • 10.1186/1742-2094-7-60, 2958904, 20929574
    • Perez-Nievas BG, Garcia-Bueno B, Madrigal JL, Leza JC. Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated. J Neuroinflammation 2010, 7:60. 10.1186/1742-2094-7-60, 2958904, 20929574.
    • (2010) J Neuroinflammation , vol.7 , pp. 60
    • Perez-Nievas, B.G.1    Garcia-Bueno, B.2    Madrigal, J.L.3    Leza, J.C.4
  • 35
    • 0034789247 scopus 로고    scopus 로고
    • Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis
    • 209380, 11544280
    • Chitnis T, Najafian N, Benou C, Salama AD, Grusby MJ, Sayegh MH, Khoury SJ. Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis. J Clin Invest 2001, 108:739-747. 209380, 11544280.
    • (2001) J Clin Invest , vol.108 , pp. 739-747
    • Chitnis, T.1    Najafian, N.2    Benou, C.3    Salama, A.D.4    Grusby, M.J.5    Sayegh, M.H.6    Khoury, S.J.7
  • 36
    • 65349149089 scopus 로고    scopus 로고
    • Molecular mechanism and function of CD40/CD40L engagement in the immune system
    • 10.1111/j.1600-065X.2009.00782.x, 19426221
    • Elgueta R, Benson MJ, de Vries VC, Wasiuk A, Guo Y, Noelle RJ. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol Rev 2009, 229:152-172. 10.1111/j.1600-065X.2009.00782.x, 19426221.
    • (2009) Immunol Rev , vol.229 , pp. 152-172
    • Elgueta, R.1    Benson, M.J.2    de Vries, V.C.3    Wasiuk, A.4    Guo, Y.5    Noelle, R.J.6
  • 37
    • 0025304044 scopus 로고
    • Beta 2-microglobulin: its significance and clinical usefulness
    • Bethea M, Forman DT. Beta 2-microglobulin: its significance and clinical usefulness. Ann Clin Lab Sci 1990, 20:163-168.
    • (1990) Ann Clin Lab Sci , vol.20 , pp. 163-168
    • Bethea, M.1    Forman, D.T.2
  • 38
    • 0035911254 scopus 로고    scopus 로고
    • Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis
    • 10.1084/jem.193.6.713, 2193420, 11257138
    • Huang DR, Wang J, Kivisakk P, Rollins BJ, Ransohoff RM. Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis. J Exp Med 2001, 193:713-726. 10.1084/jem.193.6.713, 2193420, 11257138.
    • (2001) J Exp Med , vol.193 , pp. 713-726
    • Huang, D.R.1    Wang, J.2    Kivisakk, P.3    Rollins, B.J.4    Ransohoff, R.M.5
  • 39
    • 47249098928 scopus 로고    scopus 로고
    • Production of CCL2 by central nervous system cells regulates development of murine experimental autoimmune encephalomyelitis through the recruitment of TNF- and iNOS-expressing macrophages and myeloid dendritic cells
    • Dogan RN, Elhofy A, Karpus WJ. Production of CCL2 by central nervous system cells regulates development of murine experimental autoimmune encephalomyelitis through the recruitment of TNF- and iNOS-expressing macrophages and myeloid dendritic cells. J Immunol 2008, 180:7376-7384.
    • (2008) J Immunol , vol.180 , pp. 7376-7384
    • Dogan, R.N.1    Elhofy, A.2    Karpus, W.J.3
  • 40
    • 0011791539 scopus 로고
    • Simple method for enhancing development of acute disseminated encephalomyelitis in mice
    • Lee JM, Olitsky PK. Simple method for enhancing development of acute disseminated encephalomyelitis in mice. Proc Soc Exp Biol Med 1955, 89:263-266.
    • (1955) Proc Soc Exp Biol Med , vol.89 , pp. 263-266
    • Lee, J.M.1    Olitsky, P.K.2
  • 41
    • 0015542715 scopus 로고
    • Experimental allergic encephalomyelitis in inbred and outbred mice
    • Levine S, Sowinski R. Experimental allergic encephalomyelitis in inbred and outbred mice. J Immunol 1973, 110:139-143.
    • (1973) J Immunol , vol.110 , pp. 139-143
    • Levine, S.1    Sowinski, R.2
  • 43
    • 0009671661 scopus 로고
    • Testicular and ovarian autoimmune diseases
    • Academic, San Diego, Cohen I, Miller A
    • Tung K, Taguchi O, Tester C. Testicular and ovarian autoimmune diseases. Autoimmune Disease Models 1994, 267-290. Academic, San Diego, Cohen I, Miller A.
    • (1994) Autoimmune Disease Models , pp. 267-290
    • Tung, K.1    Taguchi, O.2    Tester, C.3
  • 46
    • 0036314504 scopus 로고    scopus 로고
    • Critical involvement of p38 MAP kinase in pertussis toxin-induced cytoskeletal reorganization and lung permeability
    • 10.1096/fj.01-0895com, 12087068
    • Garcia JG, Wang P, Schaphorst KL, Becker PM, Borbiev T, Liu F, Birukova A, Jacobs K, Bogatcheva N, Verin AD. Critical involvement of p38 MAP kinase in pertussis toxin-induced cytoskeletal reorganization and lung permeability. FASEB J 2002, 16:1064-1076. 10.1096/fj.01-0895com, 12087068.
    • (2002) FASEB J , vol.16 , pp. 1064-1076
    • Garcia, J.G.1    Wang, P.2    Schaphorst, K.L.3    Becker, P.M.4    Borbiev, T.5    Liu, F.6    Birukova, A.7    Jacobs, K.8    Bogatcheva, N.9    Verin, A.D.10
  • 47
    • 0001973228 scopus 로고
    • Action of pertussigen (pertussis toxin) on the host immune system
    • Wiley, New York, Wardlaw AC, Partoin R
    • Munoz J. Action of pertussigen (pertussis toxin) on the host immune system. Pathogenesis and Immunity in Pertussis 1988, 173-187. Wiley, New York, Wardlaw AC, Partoin R.
    • (1988) Pathogenesis and Immunity in Pertussis , pp. 173-187
    • Munoz, J.1
  • 48
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice. I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system
    • 10.1016/0008-8749(82)90457-9, 6891621
    • Linthicum DS, Munoz JJ, Blaskett A. Acute experimental autoimmune encephalomyelitis in mice. I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system. Cell Immunol 1982, 73:299-310. 10.1016/0008-8749(82)90457-9, 6891621.
    • (1982) Cell Immunol , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 49
    • 0027279416 scopus 로고
    • Enhancement of histamine-induced vascular leakage by pertussis toxin in SJL/J mice but not BALB/c mice
    • 10.1016/0165-5728(93)90162-R, 8331165
    • Yong T, Meininger GA, Linthicum DS. Enhancement of histamine-induced vascular leakage by pertussis toxin in SJL/J mice but not BALB/c mice. J Neuroimmunol 1993, 45:47-52. 10.1016/0165-5728(93)90162-R, 8331165.
    • (1993) J Neuroimmunol , vol.45 , pp. 47-52
    • Yong, T.1    Meininger, G.A.2    Linthicum, D.S.3
  • 50
    • 33846930366 scopus 로고    scopus 로고
    • Pertussis toxin transiently affects barrier integrity, organelle organization and transmigration of monocytes in a human brain microvascular endothelial cell barrier model
    • 10.1111/j.1462-5822.2006.00813.x, 17002784
    • Kugler S, Bocker K, Heusipp G, Greune L, Kim KS, Schmidt MA. Pertussis toxin transiently affects barrier integrity, organelle organization and transmigration of monocytes in a human brain microvascular endothelial cell barrier model. Cell Microbiol 2007, 9:619-632. 10.1111/j.1462-5822.2006.00813.x, 17002784.
    • (2007) Cell Microbiol , vol.9 , pp. 619-632
    • Kugler, S.1    Bocker, K.2    Heusipp, G.3    Greune, L.4    Kim, K.S.5    Schmidt, M.A.6
  • 51
    • 17544401216 scopus 로고    scopus 로고
    • Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP
    • 10.1242/jcs.00378, 12665564
    • Bruckener KE, el Baya A, Galla HJ, Schmidt MA. Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP. J Cell Sci 2003, 116:1837-1846. 10.1242/jcs.00378, 12665564.
    • (2003) J Cell Sci , vol.116 , pp. 1837-1846
    • Bruckener, K.E.1    el Baya, A.2    Galla, H.J.3    Schmidt, M.A.4
  • 53
    • 0036644294 scopus 로고    scopus 로고
    • Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells
    • Hofstetter HH, Shive CL, Forsthuber TG. Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells. J Immunol 2002, 169:117-125.
    • (2002) J Immunol , vol.169 , pp. 117-125
    • Hofstetter, H.H.1    Shive, C.L.2    Forsthuber, T.G.3
  • 54
    • 19544363581 scopus 로고    scopus 로고
    • PTX cruiser: driving autoimmunity via TLR4
    • 10.1016/j.it.2005.03.012, 15922942
    • Racke MK, Hu W, Lovett-Racke AE. PTX cruiser: driving autoimmunity via TLR4. Trends Immunol 2005, 26:289-291. 10.1016/j.it.2005.03.012, 15922942.
    • (2005) Trends Immunol , vol.26 , pp. 289-291
    • Racke, M.K.1    Hu, W.2    Lovett-Racke, A.E.3
  • 55
    • 80054680995 scopus 로고    scopus 로고
    • Crawling phagocytes recruited in the brain vasculature after pertussis toxin exposure through IL6, ICAM1 and ITGalphaM
    • 10.1111/j.1750-3639.2011.00490.x, 21418369
    • Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L. Crawling phagocytes recruited in the brain vasculature after pertussis toxin exposure through IL6, ICAM1 and ITGalphaM. Brain Pathol 2011, 21:661-671. 10.1111/j.1750-3639.2011.00490.x, 21418369.
    • (2011) Brain Pathol , vol.21 , pp. 661-671
    • Richard, J.F.1    Roy, M.2    Audoy-Remus, J.3    Tremblay, P.4    Vallieres, L.5
  • 57
    • 57749189130 scopus 로고    scopus 로고
    • Caveolae and transcytosis in endothelial cells: role in atherosclerosis
    • 10.1007/s00441-008-0659-8, 18688651
    • Frank PG, Pavlides S, Lisanti MP. Caveolae and transcytosis in endothelial cells: role in atherosclerosis. Cell Tissue Res 2009, 335:41-47. 10.1007/s00441-008-0659-8, 18688651.
    • (2009) Cell Tissue Res , vol.335 , pp. 41-47
    • Frank, P.G.1    Pavlides, S.2    Lisanti, M.P.3
  • 58
    • 39749175539 scopus 로고    scopus 로고
    • Transcellular transport of CCL2 across brain microvascular endothelial cells
    • 10.1111/j.1471-4159.2007.05056.x, 18289346
    • Ge S, Song L, Serwanski DR, Kuziel WA, Pachter JS. Transcellular transport of CCL2 across brain microvascular endothelial cells. J Neurochem 2008, 104:1219-1232. 10.1111/j.1471-4159.2007.05056.x, 18289346.
    • (2008) J Neurochem , vol.104 , pp. 1219-1232
    • Ge, S.1    Song, L.2    Serwanski, D.R.3    Kuziel, W.A.4    Pachter, J.S.5
  • 59
    • 77951668726 scopus 로고    scopus 로고
    • Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation
    • 10.1093/cvr/cvq075, 2856194, 20202978
    • Chidlow JH, Sessa WC. Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation. Cardiovasc Res 2010, 86:219-225. 10.1093/cvr/cvq075, 2856194, 20202978.
    • (2010) Cardiovasc Res , vol.86 , pp. 219-225
    • Chidlow, J.H.1    Sessa, W.C.2
  • 60
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • 10.1146/annurev-physiol-021909-135833, 20148685
    • Komarova Y, Malik AB. Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol 2010, 72:463-493. 10.1146/annurev-physiol-021909-135833, 20148685.
    • (2010) Annu Rev Physiol , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 61
    • 0031179652 scopus 로고    scopus 로고
    • Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis
    • Brabb T, Goldrath AW, von Dassow P, Paez A, Liggitt HD, Goverman J. Triggers of autoimmune disease in a murine TCR-transgenic model for multiple sclerosis. J Immunol 1997, 159:497-507.
    • (1997) J Immunol , vol.159 , pp. 497-507
    • Brabb, T.1    Goldrath, A.W.2    von Dassow, P.3    Paez, A.4    Liggitt, H.D.5    Goverman, J.6
  • 62
    • 58249084574 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 in the choroid plexus: a potential link between vascular pro-inflammatory mediators and the CNS during peripheral tissue inflammation
    • 10.1016/j.neuroscience.2008.10.047, 2668531, 19032979
    • Mitchell K, Yang HY, Berk JD, Tran JH, Iadarola MJ. Monocyte chemoattractant protein-1 in the choroid plexus: a potential link between vascular pro-inflammatory mediators and the CNS during peripheral tissue inflammation. Neuroscience 2009, 158:885-895. 10.1016/j.neuroscience.2008.10.047, 2668531, 19032979.
    • (2009) Neuroscience , vol.158 , pp. 885-895
    • Mitchell, K.1    Yang, H.Y.2    Berk, J.D.3    Tran, J.H.4    Iadarola, M.J.5
  • 63
    • 84865344876 scopus 로고    scopus 로고
    • Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation
    • 10.1186/2045-8118-9-10, 3422203, 22546091
    • Schellenberg AE, Buist R, Del Bigio MR, Khorooshi R, Toft-Hansen H, Owens T, Peeling J. Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation. Fluids Barriers CNS 2012, 9:10. 10.1186/2045-8118-9-10, 3422203, 22546091.
    • (2012) Fluids Barriers CNS , vol.9 , pp. 10
    • Schellenberg, A.E.1    Buist, R.2    Del Bigio, M.R.3    Khorooshi, R.4    Toft-Hansen, H.5    Owens, T.6    Peeling, J.7
  • 64
    • 0027468174 scopus 로고
    • Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity
    • 10.1016/0092-8674(93)90074-Z, 7679952
    • Goverman J, Woods A, Larson L, Weiner LP, Hood L, Zaller DM. Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity. Cell 1993, 72:551-560. 10.1016/0092-8674(93)90074-Z, 7679952.
    • (1993) Cell , vol.72 , pp. 551-560
    • Goverman, J.1    Woods, A.2    Larson, L.3    Weiner, L.P.4    Hood, L.5    Zaller, D.M.6
  • 65
    • 78651073831 scopus 로고    scopus 로고
    • Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin
    • 10.1016/j.cellimm.2010.11.003, 3062196, 21130421
    • Murphey C, Chang S, Zhang X, Arulanandam B, Forsthuber TG. Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin. Cell Immunol 2011, 267:50-55. 10.1016/j.cellimm.2010.11.003, 3062196, 21130421.
    • (2011) Cell Immunol , vol.267 , pp. 50-55
    • Murphey, C.1    Chang, S.2    Zhang, X.3    Arulanandam, B.4    Forsthuber, T.G.5
  • 66
    • 70149097173 scopus 로고    scopus 로고
    • CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells
    • 10.4049/jimmunol.0800729, 19625643
    • Kuwabara T, Ishikawa F, Yasuda T, Aritomi K, Nakano H, Tanaka Y, Okada Y, Lipp M, Kakiuchi T. CCR7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells. J Immunol 2009, 183:2513-2521. 10.4049/jimmunol.0800729, 19625643.
    • (2009) J Immunol , vol.183 , pp. 2513-2521
    • Kuwabara, T.1    Ishikawa, F.2    Yasuda, T.3    Aritomi, K.4    Nakano, H.5    Tanaka, Y.6    Okada, Y.7    Lipp, M.8    Kakiuchi, T.9
  • 68
    • 79551558143 scopus 로고    scopus 로고
    • MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium
    • 10.1152/ajplung.00292.2010, 3043814, 21097527
    • Monzon ME, Forteza RM, Casalino-Matsuda SM. MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium. Am J Physiol Lung Cell Mol Physiol 2011, 300:L204-L215. 10.1152/ajplung.00292.2010, 3043814, 21097527.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.300
    • Monzon, M.E.1    Forteza, R.M.2    Casalino-Matsuda, S.M.3
  • 69
    • 69949181067 scopus 로고    scopus 로고
    • Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis
    • 10.1111/j.1365-2249.2009.03993.x, 2759069, 19737241
    • van der Veen BS, Petersen AH, Belperio JA, Satchell SC, Mathieson PW, Molema G, Heeringa P. Spatiotemporal expression of chemokines and chemokine receptors in experimental anti-myeloperoxidase antibody-mediated glomerulonephritis. Clin Exp Immunol 2009, 158:143-153. 10.1111/j.1365-2249.2009.03993.x, 2759069, 19737241.
    • (2009) Clin Exp Immunol , vol.158 , pp. 143-153
    • van der Veen, B.S.1    Petersen, A.H.2    Belperio, J.A.3    Satchell, S.C.4    Mathieson, P.W.5    Molema, G.6    Heeringa, P.7
  • 71
    • 71549130733 scopus 로고    scopus 로고
    • The choroid plexus response to a repeated peripheral inflammatory stimulus
    • 10.1186/1471-2202-10-135, 2784788, 19922669
    • Marques F, Sousa JC, Coppola G, Geschwind DH, Sousa N, Palha JA, Correia-Neves M. The choroid plexus response to a repeated peripheral inflammatory stimulus. BMC Neurosci 2009, 10:135. 10.1186/1471-2202-10-135, 2784788, 19922669.
    • (2009) BMC Neurosci , vol.10 , pp. 135
    • Marques, F.1    Sousa, J.C.2    Coppola, G.3    Geschwind, D.H.4    Sousa, N.5    Palha, J.A.6    Correia-Neves, M.7
  • 72
    • 77949358391 scopus 로고    scopus 로고
    • Major histocompatibility complex class I expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis
    • 10.1002/cne.22259, 20127802
    • Freria CM, Zanon RG, Santos LM, Oliveira AL. Major histocompatibility complex class I expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis. J Comp Neurol 2010, 518:990-1007. 10.1002/cne.22259, 20127802.
    • (2010) J Comp Neurol , vol.518 , pp. 990-1007
    • Freria, C.M.1    Zanon, R.G.2    Santos, L.M.3    Oliveira, A.L.4
  • 73
    • 68349106753 scopus 로고    scopus 로고
    • Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord
    • 10.1186/1477-5956-7-25, 2716311, 19607715
    • Jain MR, Bian S, Liu T, Hu J, Elkabes S, Li H. Altered proteolytic events in experimental autoimmune encephalomyelitis discovered by iTRAQ shotgun proteomics analysis of spinal cord. Proteome Sci 2009, 7:25. 10.1186/1477-5956-7-25, 2716311, 19607715.
    • (2009) Proteome Sci , vol.7 , pp. 25
    • Jain, M.R.1    Bian, S.2    Liu, T.3    Hu, J.4    Elkabes, S.5    Li, H.6
  • 74
    • 34247263694 scopus 로고    scopus 로고
    • Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease
    • 10.1016/j.molimm.2007.02.002, 1986644, 17353050
    • Szalai AJ, Hu X, Adams JE, Barnum SR. Complement in experimental autoimmune encephalomyelitis revisited: C3 is required for development of maximal disease. Mol Immunol 2007, 44:3132-3136. 10.1016/j.molimm.2007.02.002, 1986644, 17353050.
    • (2007) Mol Immunol , vol.44 , pp. 3132-3136
    • Szalai, A.J.1    Hu, X.2    Adams, J.E.3    Barnum, S.R.4
  • 75
    • 73449115641 scopus 로고    scopus 로고
    • The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction
    • 10.1007/s00281-009-0177-0, 19779720
    • Engelhardt B, Sorokin L. The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction. Semin Immunopathol 2009, 31:497-511. 10.1007/s00281-009-0177-0, 19779720.
    • (2009) Semin Immunopathol , vol.31 , pp. 497-511
    • Engelhardt, B.1    Sorokin, L.2


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