Spermatid count as a predictor of response to FSH therapy

Reproductive BioMedicine Online

Volumn 29, Issue 1, 2014, Pages 102-112

  Garolla, Andrea ^a   Selice, Riccardo ^a   Engl, Bruno ^b   Bertoldo, Alessandro ^a   Menegazzo, Massimo ^a   Finos, Livio ^a   Lenzi, Andrea ^c   Foresta, Carlo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b Obstetrics and Gynaecology Unit   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Assisted reproduction outcome; FSH therapy; male infertility; pregnancy rate; severe oligozoospermia; spermatid count

Indexed keywords

FOLLITROPIN; UROFOLLITROPIN;

ADULT; ANEUPLOIDY; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; EMBRYO TRANSFER; FERTILIZATION IN VITRO; FINE NEEDLE ASPIRATION BIOPSY; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLITROPIN BLOOD LEVEL; FOLLOW UP; HORMONAL THERAPY; HUMAN; HYPOSPERMATOGENESIS; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; INTRAUTERINE INSEMINATION; MAJOR CLINICAL STUDY; MALE; MALE INFERTILITY; NICK END LABELING; OBSTRUCTION; OLIGOSPERMIA; PATIENT SELECTION; PREGNANCY OUTCOME; PREGNANCY RATE; SEMEN ANALYSIS; SPERMATID; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS BIOPSY; TESTIS DISEASE; TREATMENT DURATION; TREATMENT RESPONSE; CELL COUNT; CYTOLOGY; DRUG EFFECTS; FEMALE; MIDDLE AGED; PATHOLOGY; PREGNANCY; SPERMATOZOON;

ADULT; CELL COUNT; FEMALE; FOLLICLE STIMULATING HORMONE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; IN SITU NICK-END LABELING; MALE; MIDDLE AGED; OLIGOSPERMIA; PREGNANCY; PREGNANCY RATE; SEMEN ANALYSIS; SPERMATIDS; SPERMATOZOA;

EID: 84904053134     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2014.02.014     Document Type: Article

References (56)

1. A.A. Acosta, S. Oehninger, H. Ertunc, and C. Philput Possible role of pure human follicle-stimulating hormone in the treatment of severe male infertility by assisted reproduction: preliminary report Fertil. Steril. 55 1991 1150 1156
2. A.A. Acosta, E. Khalifa, and S. Oehninger Pure human follicle stimulating hormone has a role in the treatment of severe male infertility by assisted reproduction: Norfolk's total experience Hum. Reprod. 7 1992 1067 1072
3. R.C. Adhikari Testicular fine needle aspiration cytology in azoospermic males Nepal Med. Coll. J. 11 2009 88 91
4. K. Aittomaki, J.L. Lucena, P. Pakarinen, P. Sistonen, J. Tapanainen, J. Gromoll, R. Kaskikari, E.M. Sankila, H. Lehväslaiho, A.R. Engel, E. Nieschlag, A. Huhtaniemi, and A. de la Chapelle Mutation in the follicle-stimulating hormone receptor gene causes hereditary hypergonadotropic ovarian failure Cell 82 1995 959 968
5. J. Ashkenazi, A. Bar-Hava, J. Farhi, T. Levy, D. Feldberg, R. Orvieto, and Z. Ben-Rafael The role of purified follicle stimulating hormone therapy in the male partner before intracytoplasmic sperm injection Fertil. Steril. 72 1999 670 673
6. A.M. Attia, H.G. Al-Inany, C. Farquhar, and M. Proctor Gonadotrophins for idiopathic male factor subfertility Cochrane Database Syst. Rev. 17 2007 CD005071
7. B. Baccetti, E. Strehler, S. Capitani, G. Collodel, M. De Santo, E. Moretti, P. Piomboni, R. Wiedeman, and K. Sterzik The effect of follicle stimulating hormone therapy on human sperm structure (Notulae seminologicae) Hum. Reprod. 12 1997 1955 1968
8. M.A. Baker, and R.J. Aitken Reactive oxygen species in spermatozoa: methods for monitoring and significance for the origins of genetic disease and infertility Reprod. Biol. Endocrinol. 3 2005 67
9. B. Bartoov, F. Eltes, E. Lunenfeld, D. Har-Even, H. Lederman, and B. Lunenfeld Sperm quality of subfertile males before and after treatment with human follicle-stimulating hormone Fertil. Steril. 61 1994 727 734
10. H.M. Behre, R.R. Greb, A. Mempel, B. Sonntag, L. Kiesel, P. Kaltwasser, E. Seliger, F. Röpke, J. Gromoll, E. Nieschlag, and M. Simoni Significance of a common single nucleotide polymorphism in exon 10 of the follicle-stimulating hormone (FSH) receptor gene for the ovarian response to FSH: a pharmacogenetic approach to controlled ovarian hyperstimulation Pharmacogenet. Genom. 15 2005 451 456
11. S. Bhasin Approach to the infertile man J. Clin. Endocrinol. Metab. 92 2007 1995 2004
12. N. Colacurci, M.G. Monti, F. Fornaro, G. Izzo, P. Izzo, C. Trotta, D. Mele, and P. De Franciscis Recombinant human FSH reduces sperm DNA fragmentation in men with idiopathic oligoasthenoteratozoospermia J. Androl. 33 2012 588 593
13. D.P. Evenson, and R. Wixon Data analysis of two in vivo fertility studies using Sperm Chromatin Structure Assay-derived DNA fragmentation index vs. pregnancy outcome Fertil. Steril. 90 2008 1229 1231
14. A. Ferlin, C. Vinanzi, R. Selice, A. Garolla, A.C. Frigo, and C. Foresta Toward a pharmacogenetic approach to male infertility: polymorphism of follicle-stimulating hormone beta-subunit promoter Fertil. Steril. 96 2011 1344 1349
15. C. Foresta, and A. Varotto Assessment of testicular cytology by fine needle aspiration as a diagnostic parameter in the evaluation of the oligospermia subject Fertil. Steril. 58 1992 1028 1033
16. C. Foresta, A. Varotto, and C. Scandellari Assessment of testicular cytology by fine needle aspiration as a diagnostic parameter in the evaluation of the azoospermic subject Fertil. Steril. 57 1992 858 865
17. C. Foresta, A. Ferlin, A. Bettella, M. Rossato, and A. Varotto Diagnostic and clinical features in azoospermia Clin. Endocrinol. 43 1995 537 543
18. C. Foresta, C. Galeazzi, A. Bettella, M. Stella, and C. Scandellari High incidence of sperm sex chromosomes aneuploidies in two patients with Klinefelter's syndrome J. Clin. Endocrinol. Metab. 83 1998 203 205
19. C. Foresta, A. Bettella, M. Merico, A. Garolla, M. Plebani, A. Ferlin, and M. Rossato FSH in the treatment of oligozoospermia Mol. Cell. Endocrinol. 161 2000 89 97
20. C. Foresta, A. Bettella, M. Merico, A. Garolla, A. Ferlin, and M. Rossato Use of recombinant human follicle-stimulating hormone in the treatment of male factor infertility Fertil. Steril. 77 2002 238 244
21. C. Foresta, A. Bettella, A. Garolla, G. Ambrosini, and A. Ferlin Treatment of male idiopathic infertility with recombinant human follicle-stimulating hormone: a prospective, controlled, randomized clinical study Fertil. Steril. 84 2005 654 661
22. C. Foresta, R. Selice, A. Ferlin, P. Arslan, and A. Garolla Hormonal treatment of male infertility: FSH Reprod. Biomed.Online 15 2007 666 672
23. C. Foresta, R. Selice, A. Moretti, M.A. Pati, M. Carraro, B. Engl, and A. Garolla Gonadotropin administration after gonadotropin-releasing-hormone agonist: a therapeutic option in severe testiculopathies Fertil. Steril. 92 2009 1326 1332
24. L. Gandini, A. Lenzi, F. Lombardo, R. Pacifici, and F. Dondero Immature germ cell separation using a modified discontinuous Percoll gradient technique in human semen Hum. Reprod. 14 1999 1022 1027
25. H.J. Glander, and J. Kratzsch Effects of pure human follicle-stimulating hormone (pFSH) on sperm quality correlate with the hypophyseal response to gonadotropin-releasing hormone (GnRH) Andrologia 29 1997 23 28
26. R.R. Greb, K. Grieshaber, J. Gromoll, B. Sonntag, E. Nieschlag, L. Kiesel, and M. Simoni A common single nucleotide polymorphism in exon 10 of the human follicle stimulating hormone receptor is a major determinant of length and hormonal dynamics of the menstrual cycle J. Clin. Endocrinol. Metab. 90 2005 4866 4872
27. M. Grigorova, K. Rull, and M. Laan Haplotype structure of FSHB, the beta-subunit gene for fertility-associated follicle-stimulating hormone: possible influence of balancing selection Ann. Hum. Genet. 71 2007 18 28
28. M. Grigorova, M. Punab, K. Ausmees, and M. Laan FSHB promoter polymorphism within evolutionary conserved element is associated with serum FSH level in men Hum. Reprod. 23 2008 2160 2166
29. T.G. Jenkins, and D.T. Carrell The sperm epigenome and potential implications for the developing embryo Reproduction 143 2012 727 734
30. U.B. Hacker-Klom, W. Göhde, E. Nieschlag, and H.M. Behre DNA flow cytometry of human semen Hum. Reprod. 14 1999 2506 2512
31. A. Kamischke, H.M. Behre, M. Bergmann, M. Simoni, T. Schäfer, and E. Nieschlag Recombinant human follicle stimulating hormone for treatment of male idiopathic infertility: a randomized, double-blind, placebo-controlled, clinical trial Hum. Reprod. 13 1998 596 603
32. M.R. Khalil, P.E. Rasmussen, K. Erb, S.B. Laursen, S. Rex, and L.G. Westergaard Homologous intrauterine insemination. An evaluation of prognostic factors based on a review of 2473 cycles Acta Obstet. Gynecol. Scand. 80 2001 74 81
33. C. Lalancette, A.E. Platts, G.D. Johnson, B.R. Emery, D.T. Carrell, and S.A. Krawetz Identification of human sperm transcripts as candidate markers of male fertility J. Mol. Med. 87 2009 735 748
34. S. La Vignera, E. Vicari, R.A. Condorelli, R. D'Agata, and A.E. Calogero Male accessory gland infection and sperm parameters Int. J. Androl. 34 2011 e330 e347
35. A. Lenzi, G. Balercia, A. Bellastella, A. Colao, A. Fabbri, C. Foresta, M. Galdiero, L. Gandini, C. Krausz, G. Lombardi, F. Lombardo, M. Maggi, A. Radicioni, R. Selice, A.A. Sinisi, and G. Forti Epidemiology, diagnosis, and treatment of male hypogonadotropic hypogonadism J. Endocrinol. Invest. 32 2009 934 938
36. N. Levek-Motola, Y. Soffer, L. Shochat, A. Raziel, L.M. Lewin, and R. Golan Flow cytometry of human semen: a preliminary study of a non-invasive method for the detection of spermatogenetic defects Hum. Reprod. 20 2005 3469 3475
37. G.R. Marshall, D.S. Zorub, and T.M. Plant Follicle-stimulating hormone amplifies the population of differentiated spermatogonial in the hypophysectomized testosterone-replaced adult rhesus monkey (Macaca mulatta) Endocrinology 136 1995 3504 3511
38. R. Matorras, C. Pérez, B. Corcóstegui, J.A. Pijoan, O. Ramón, P. Delgado, and F.J. Rodríguez-Escudero Treatment of the male with follicle-stimulating hormone in intrauterine insemination with husband's spermatozoa: a randomized study Hum. Reprod. 12 1997 24 28
39. A.M. Matsumoto Hormonal control of human spermatogenesis H. Burger, D. de Kretser, The Testis 1989 Raven Press New York 181 196
40. R.A. McLachlan, N.G. Wreford, D.M. de Kretser, and D.M. Robertson The effects of recombinant follicle-stimulating hormone on restoration of spermatogenesis in gonadotropin releasing hormone-immunized adult rat Endocrinology 136 1995 4035 4043
41. G. Merino, S. Carranza-Lira, and J.C. Martinez-Chequer Sperm characteristics and hormonal profile bifore and after treatment with follicle-stimulating hormone in infertile patients Arch. Androl. 37 1996 197 200
42. D. Montjean, C. Ravel, M. Benkhalifa, P. Cohen-Bacrie, A. Berthaut, A. Bashamboo, and K. McElreavey Methylation changes in mature sperm deoxyribonucleic acid from oligozoospermic men: assessment of genetic variants and assisted reproductive technology outcome Fertil. Steril. 100 2013 1241 1247
43. N.R. Moudgal, G.S. Murthy, K.M. Prasanna kumar, F. Martin, R. Suresh, R. Medhamurthy, S. Patil, S. Sehgal, and B.N. Saxena Responsiveness of human male volunteers to immunization with ovine follicle stimulating hormone vaccine: results of a pilot study Hum. Reprod. 12 1997 457 463
44. J. O'Brien, and A. Zini Sperm DNA integrity and male infertility Urology 65 2005 16 22
45. S. Oehninger Clinical and laboratory management of male infertility: an opinion on its current status J. Androl. 6 2000 814 821
46. W.A. Robbins, J.E. Baulch, D. Moore 2nd, H.U. Weier, D. Blakey, and A.J. Wyrobek Three-probe fluorescence in situ hybridization to assess chromosome X, Y, and 8 aneuploidy in sperm of 14 men from two healthy groups: evidence or a paternal age effect on sperm aneuploidy Reprod. Fertil. Dev. 7 1995 799 809
47. R. Selice, A. Garolla, M. Pengo, N. Caretta, A. Ferlin, and C. Foresta The response to FSH treatment in oligozoospermic men depends on FSH receptor gene polymorphisms Int. J. Androl. 34 2011 306 312
48. R.M. Sharpe Follicle-stimulating hormone and spermatogenesis in adult male J. Endocrinol. 57 1989 152 159
49. E. Strehler, K. Sterzik, M. De Santo, M. Abt, R. Wiedemann, U. Bellati, G. Collodel, P. Piomboni, and B. Baccetti The effect of follicle-stimulating hormone therapy on sperm quality: an ultrastructural mathematical evaluation J. Androl. 18 1997 439 447
50. J. Tesarik, E. Greco, and C. Mendoza Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation Hum. Reprod. 19 2004 611 615
51. O. Timm Jr.; A.P. Cedenho, D.M. Spaine, M.H. Buttignol, R. Fraietta, V. Ortiz, and M. Srougi Search and identification of spermatozoa and spermatids in the ejaculate of non-obstructive azoospermic patients Int. Braz. J. Urol. 31 2005 42 48
52. F. Tüttelmann, M. Laan, M. Grigorova, M. Punab, S. Sõber, and J. Gromoll Combined effects of the variants FSHB -211G>T and FSHR 2039A>G on male reproductive parameters J. Clin. Endocrinol. Metab. 97 2012 3639 3647
53. S. Venkatesh, M. Deecaraman, R. Kumar, M.B. Shamsi, and R. Dada Role of reactive oxygen species in the pathogenesis of mitochondrial DNA (mtDNA) mutations in male infertility Indian J. Med. Res. 129 2009 127 137
54. World Health Organization WHO Laboratory Manual for the Examination and Processing of Human Semen fifth ed. 2010 WHO Press Geneva, Switzerland
55. C.H. Yeung, L. Beiglböck-Karau, F. Tüttelmann, and E. Nieschlag The presence of germ cells in the semen of azoospermic, cryptozoospermic and severe oligozoospermic patients: stringent flow cytometric analysis and correlations with hormonal status Clin. Endocrinol. 67 2007 767 775
56. A. Zini, and J. Libman Sperm DNA damage: clinical significance in the era of assisted reproduction Can. Med. Assoc. J. 175 2006 495 500