Unified synthesis of (-)-folicanthine and (-)-ditryptophenaline enabled by a room temperature nickel-mediated reductive dimerization

Synthesis (Germany)

Volumn 46, Issue 14, 2014, Pages 1908-1916

  Luo, Long ^a   Zhang, Jian Jian ^a   Ling, Wei Jian ^a   Shao, Yong Liang ^a   Wang, Ya Wen ^a   Peng, Yu ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

dimeric alkaloids; nickel catalysis; reductive homocoupling; total synthesis; vicinal quaternary stereocenters

Indexed keywords

ALKALOIDS; CARBOXYLATION; METABOLITES; NITROGEN COMPOUNDS; SYNTHESIS (CHEMICAL);

DIMERIC ALKALOIDS; HOMOCOUPLING; NICKEL CATALYSIS; QUATERNARY STEREOCENTERS; TOTAL SYNTHESIS;

NICKEL;

1,1',8,8' TETRA TERT BUTYL 2,2' DIMETHYL 2,2',3,3' TETRAHYDRO 1H,1'H 3A,3'A BIPYRROLO[2,3 B]INDOLE 1,1',2,2',8,8' HEXACARBOXYLIC ACID; 1,8 DI TERT BUTYL 2 METHYL 3A BROMO 3,3A DIHYDROPYRROLO [2,3 B]INDOLE 1,2,8 TRICARBOXYLIC ACID; BROMINE DERIVATIVE; DIMETHYL 1,1' BIS[2 [TERT BUTOXYCARBONYL(METHYL)AMINO] 3 PHENYLPROPANOYL]2,2',3,3',8,8A,8',8'A OCTAHYDRO 1H,1'H 3A,3'A BIPYRROLO[2,3 B]INDOLE 2,2' DICARBOXYLIC ACID; DIMETHYL 1,1',8,8' TETRAMETHYL 2,2',3,3',8,8A,8',8'A OCTAHYDRO 1H,1'H 3A,3'A BIPYRROLO[2,3 B]INDOLE 2,2' DICARBOXYLIC ACID; DIMETHYL 2,2',3,3',8,8A,8',8'A OCTAHYDRO 1H,1'H 3A,3'A BIPYRROLO[2,3 B]INDOLE 2,2' DICARBOXYLIC ACID; DITRYPTOPHENALINE; FOLICANTHINE; FUNCTIONAL GROUP; NICKEL; TERT BUTYL 2,2',3,3' TETRAHYDRO 1H 1'H 3A,3'A BIPYRROLO[2,3 B]INDOLE 1,1',8,8' TETRACARBOXYLIC ACID; TERT BUTYL 3 [2 (TERT BUTOXYCARBONYLAMINO) 3 METHOXY 3 OXOPROPYL] 1H INDOLE 1 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CROSS COUPLING REACTION; DECARBOXYLATION; DIMERIZATION; ESTERIFICATION; ROOM TEMPERATURE; STOICHIOMETRY;

EID: 84904046210     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0033-1339126     Document Type: Article

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