Disruption of histamine H2 receptor slows heart failure progression through reducing myocardial apoptosis and fibrosis

Clinical Science

Volumn 127, Issue 7, 2014, Pages 435-448

  Zeng, Zhi ^a   Shen, Liang ^a   Li, Xixian ^a   Luo, Tao ^a   Wei, Xuan ^a   Zhang, Jingwen ^a   Cao, Shiping ^a   Huang, Xiaobo ^a   Fukushima, Yasushi ^b   Bin, Jianping ^a   Kitakaze, Masafumi ^a,c   Xu, Dingli ^a   Liao, Yulin ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Apoptosis; Calcineurin; Fibrosis; Hypertrophy

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CALCINEURIN; CALMODULIN; CASPASE 3; FAMOTIDINE; FIBRONECTIN; HISTAMINE H2 RECEPTOR; INOSITOL TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROCOLLAGEN; SHORT HAIRPIN RNA; TUMOR NECROSIS FACTOR ALPHA; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA CONSTRICTION; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; FIBROBLAST; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HISTAMINE RELEASE; KNOCKOUT MOUSE; LUNG CONGESTION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESSURE GRADIENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSTHORACIC ECHOCARDIOGRAPHY; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; FIBROSIS; GENE INACTIVATION; GENETICS; HEART MUSCLE; HEMODYNAMICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PERMEABILITY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CALCINEURIN; DISEASE PROGRESSION; FIBROSIS; GENE KNOCKOUT TECHNIQUES; HEART FAILURE; HEMODYNAMICS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MODELS, BIOLOGICAL; MYOCARDIUM; PERMEABILITY; RECEPTORS, HISTAMINE H2;

EID: 84904015166     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20130716     Document Type: Article

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