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Volumn 6, Issue 1, 2012, Pages 5-14

Angiotensin II signalling and calcineurin in cardiac fibroblasts: Differential effects of calcineurin inhibitors FK506 and cyclosporine A

Author keywords

heart; immunomodulators; MAP kinase; signal transduction

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; CALCINEURIN; COLLAGEN; CYCLINE; CYCLOSPORIN A; FIBRONECTIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TACROLIMUS;

EID: 84856730362     PISSN: 17539447     EISSN: 17539455     Source Type: Journal    
DOI: 10.1177/1753944711432901     Document Type: Article
Times cited : (13)

References (46)
  • 1
    • 53149099360 scopus 로고    scopus 로고
    • Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506
    • Akool S. Doller A. Babelova A. Tsalastra W. Moreth K. Schaefer L. et al. (2008) Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506. J Immunol 181: 2831–2845.
    • (2008) J Immunol , vol.181 , pp. 2831-2845
    • Akool, S.1    Doller, A.2    Babelova, A.3    Tsalastra, W.4    Moreth, K.5    Schaefer, L.6
  • 2
    • 77956918119 scopus 로고    scopus 로고
    • Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy waters be cleared?
    • Balakumar P. Jagadeesh G. (2010) Multifarious molecular signaling cascades of cardiac hypertrophy: can the muddy waters be cleared? Pharmacol Res 62: 365–383.
    • (2010) Pharmacol Res , vol.62 , pp. 365-383
    • Balakumar, P.1    Jagadeesh, G.2
  • 4
    • 77957079503 scopus 로고    scopus 로고
    • What causes a broken heart–molecular insights into heart failure
    • Barry S.P. Townsend P.A. (2010) What causes a broken heart–molecular insights into heart failure. Int Rev Cell Mol Biol 284: 113–179.
    • (2010) Int Rev Cell Mol Biol , vol.284 , pp. 113-179
    • Barry, S.P.1    Townsend, P.A.2
  • 5
    • 0027325247 scopus 로고
    • FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818
    • Becker J.W. Rotonda J. McKeever B.M. Chan H.K. Marcy A.I. Wiederrecht G. et al. (1993) FK-506-binding protein: three-dimensional structure of the complex with the antagonist L-685,818. J Biol Chem 268:11335-11339.
    • (1993) J Biol Chem , vol.268 , pp. 11335-11339
    • Becker, J.W.1    Rotonda, J.2    McKeever, B.M.3    Chan, H.K.4    Marcy, A.I.5    Wiederrecht, G.6
  • 6
    • 0027527305 scopus 로고
    • Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology
    • Bierer B.E. Holländer G. Fruman D. Burakoff S.J. (1993) Cyclosporin A and FK506: molecular mechanisms of immunosuppression and probes for transplantation biology. Curr Opin Immunol: 763–773.
    • (1993) Curr Opin Immunol , pp. 763-773
    • Bierer, B.E.1    Holländer, G.2    Fruman, D.3    Burakoff, S.J.4
  • 7
    • 0028852791 scopus 로고
    • Three-dimensional structure and actions of immunosuppressants and their immunophilins
    • Braun W. Kallen J. Mikol V. Walkinshaw M.D. Wüthrich K. (1995) Three-dimensional structure and actions of immunosuppressants and their immunophilins. FASEB J 9: 63–72.
    • (1995) FASEB J , vol.9 , pp. 63-72
    • Braun, W.1    Kallen, J.2    Mikol, V.3    Walkinshaw, M.D.4    Wüthrich, K.5
  • 8
    • 34347403248 scopus 로고    scopus 로고
    • Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses
    • Clerk A. Cullingford T.E. Fuller S.J. Giraldo A. Markou T. Pikkarainen S. et al. (2007) Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses. J Cell Physiol 212: 311–322.
    • (2007) J Cell Physiol , vol.212 , pp. 311-322
    • Clerk, A.1    Cullingford, T.E.2    Fuller, S.J.3    Giraldo, A.4    Markou, T.5    Pikkarainen, S.6
  • 9
    • 78650173023 scopus 로고    scopus 로고
    • Novel aspects of angiotensin II action in the heart. Implications to myocardial ischemia and heart failure
    • de Mello W.C. (2011) Novel aspects of angiotensin II action in the heart. Implications to myocardial ischemia and heart failure. Regul Pept 166: 9–14.
    • (2011) Regul Pept , vol.166 , pp. 9-14
    • de Mello, W.C.1
  • 10
    • 77953913455 scopus 로고    scopus 로고
    • Impact of different long-term maintenance immunosuppressive therapy strategies on patients’ outcome after heart transplantation
    • Dandel M. Lehmkuhl H.B. Knosalla C. Hetzer R. (2010) Impact of different long-term maintenance immunosuppressive therapy strategies on patients’ outcome after heart transplantation. Transpl Immunol 23: 93–103.
    • (2010) Transpl Immunol , vol.23 , pp. 93-103
    • Dandel, M.1    Lehmkuhl, H.B.2    Knosalla, C.3    Hetzer, R.4
  • 11
    • 0034526195 scopus 로고    scopus 로고
    • Cellular and molecular biology of cardiac transplant rejection
    • Dengler T.J. Pober J.S. (2000) Cellular and molecular biology of cardiac transplant rejection. J Nucl Cardiol 7: 669–685.
    • (2000) J Nucl Cardiol , vol.7 , pp. 669-685
    • Dengler, T.J.1    Pober, J.S.2
  • 12
    • 0037304454 scopus 로고    scopus 로고
    • Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels
    • Dong D. Duan Y. Guo J. Roach D.E. Swirp S.L. Wang L. et al. (2003) Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels. Cardiovasc Res 57: 320–332.
    • (2003) Cardiovasc Res , vol.57 , pp. 320-332
    • Dong, D.1    Duan, Y.2    Guo, J.3    Roach, D.E.4    Swirp, S.L.5    Wang, L.6
  • 13
    • 3242770551 scopus 로고    scopus 로고
    • Interference of antihypertrophic molecules and signaling pathways with the Ca2+-calcineurin-NFAT cascade in cardiac myocytes
    • Fiedler B. Wollert K.C. (2004) Interference of antihypertrophic molecules and signaling pathways with the Ca2+-calcineurin-NFAT cascade in cardiac myocytes. Cardiovasc Res 63: 450–457.
    • (2004) Cardiovasc Res , vol.63 , pp. 450-457
    • Fiedler, B.1    Wollert, K.C.2
  • 14
    • 33747811792 scopus 로고    scopus 로고
    • Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by delta-opioid receptor activation
    • Ikeda Y. Miura T. Sakamoto J. Miki T. Tanno M. Kobayashi H. et al. (2006) Activation of ERK and suppression of calcineurin are interacting mechanisms of cardioprotection afforded by delta-opioid receptor activation. Basic Res Cardiol 101: 418–426.
    • (2006) Basic Res Cardiol , vol.101 , pp. 418-426
    • Ikeda, Y.1    Miura, T.2    Sakamoto, J.3    Miki, T.4    Tanno, M.5    Kobayashi, H.6
  • 15
    • 39749107259 scopus 로고    scopus 로고
    • Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-A resolution
    • Kajitani K. Fujihashi M. Kobayashi Y. Shimizu S. Tsujimoto Y. Miki K. (2008) Crystal structure of human cyclophilin D in complex with its inhibitor, cyclosporin A at 0.96-A resolution. Proteins 70: 1635–1639.
    • (2008) Proteins , vol.70 , pp. 1635-1639
    • Kajitani, K.1    Fujihashi, M.2    Kobayashi, Y.3    Shimizu, S.4    Tsujimoto, Y.5    Miki, K.6
  • 16
    • 85027947959 scopus 로고    scopus 로고
    • New take on the role of angiotensin II in cardiac hypertrophy and fibrosis
    • Kurdi M. Booz G.W. (2011) New take on the role of angiotensin II in cardiac hypertrophy and fibrosis. Hypertension 57: 1034–1038.
    • (2011) Hypertension , vol.57 , pp. 1034-1038
    • Kurdi, M.1    Booz, G.W.2
  • 17
    • 84860390540 scopus 로고    scopus 로고
    • New molecular mechanisms for cardiovascular disease: transcriptional pathways and novel therapeutic targets in heart failure
    • Kuwahara K. Nakao K. (2011) New molecular mechanisms for cardiovascular disease: transcriptional pathways and novel therapeutic targets in heart failure. J Pharmacol Sci 116: 337–342.
    • (2011) J Pharmacol Sci , vol.116 , pp. 337-342
    • Kuwahara, K.1    Nakao, K.2
  • 18
    • 58149351369 scopus 로고    scopus 로고
    • A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy
    • Lorenz K. Schmitt J.P. Schmitteckert E.M. Lohse M.J. ( 2009) A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy. Nat Med 15: 75–83.
    • (2009) Nat Med , vol.15 , pp. 75-83
    • Lorenz, K.1    Schmitt, J.P.2    Schmitteckert, E.M.3    Lohse, M.J.4
  • 19
    • 81355132744 scopus 로고    scopus 로고
    • Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes
    • Lunde I.G. Kvaløy H. Austbo B. Christensen G. Carlson C.R. (2011) Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes. J Appl Physiol 111: 1278–1289.
    • (2011) J Appl Physiol , vol.111 , pp. 1278-1289
    • Lunde, I.G.1    Kvaløy, H.2    Austbo, B.3    Christensen, G.4    Carlson, C.R.5
  • 20
    • 0141484390 scopus 로고    scopus 로고
    • Regulation of MAPK signaling pathways through immunophilin-ligand complex
    • Matsuda S. Koyasu S. (2003) Regulation of MAPK signaling pathways through immunophilin-ligand complex. Curr Top Med Chem 3: 1358–1367.
    • (2003) Curr Top Med Chem , vol.3 , pp. 1358-1367
    • Matsuda, S.1    Koyasu, S.2
  • 21
    • 0034331937 scopus 로고    scopus 로고
    • Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation
    • Matsuda S. Shibasaki F. Takehana K. Mori H. Nishida E. Koyasu S. (2000) Two distinct action mechanisms of immunophilin-ligand complexes for the blockade of T-cell activation. EMBO Rep 1: 428–434.
    • (2000) EMBO Rep , vol.1 , pp. 428-434
    • Matsuda, S.1    Shibasaki, F.2    Takehana, K.3    Mori, H.4    Nishida, E.5    Koyasu, S.6
  • 22
    • 33845318883 scopus 로고    scopus 로고
    • Tacrolimus: in heart transplant recipients
    • McCormack P.L. Keating G.M. (2006) Tacrolimus: in heart transplant recipients. Drugs 66: 2269–2279.
    • (2006) Drugs , vol.66 , pp. 2269-2279
    • McCormack, P.L.1    Keating, G.M.2
  • 23
    • 0034721924 scopus 로고    scopus 로고
    • Calcineurin and beyond: cardiac hypertrophic signaling
    • Molkentin J.D. (2000) Calcineurin and beyond: cardiac hypertrophic signaling. Circ Res 87: 731–738.
    • (2000) Circ Res , vol.87 , pp. 731-738
    • Molkentin, J.D.1
  • 24
    • 52449122086 scopus 로고    scopus 로고
    • Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways
    • Montezano A.C. Callera G.E. Yogi A. He Y. Tostes R.C. He G. et al. (2008) Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol 28: 1511–1518.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1511-1518
    • Montezano, A.C.1    Callera, G.E.2    Yogi, A.3    He, Y.4    Tostes, R.C.5    He, G.6
  • 25
    • 34249706297 scopus 로고    scopus 로고
    • Tacrolimus in heart transplant recipients: an overview
    • Patel J.K. Kobashigawa J.A. (2007) Tacrolimus in heart transplant recipients: an overview. BioDrugs 21: 139–143.
    • (2007) BioDrugs , vol.21 , pp. 139-143
    • Patel, J.K.1    Kobashigawa, J.A.2
  • 26
    • 0042393566 scopus 로고    scopus 로고
    • Calcineurin antagonists differentially affect mediator secretion, p 38 mitogen-activated protein kinase and extracellular signal-regulated kinases from immunologically activated human basophils
    • Plath K.E. Grabbe J. Gibbs B.F. (2003) Calcineurin antagonists differentially affect mediator secretion, p 38 mitogen-activated protein kinase and extracellular signal-regulated kinases from immunologically activated human basophils. Clin Exp Allergy 33: 342–350.
    • (2003) Clin Exp Allergy , vol.33 , pp. 342-350
    • Plath, K.E.1    Grabbe, J.2    Gibbs, B.F.3
  • 27
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: at the heart of myocardial remodeling
    • Porter K.E. Turner N.A. (2009) Cardiac fibroblasts: at the heart of myocardial remodeling. Pharmacol Ther 123: 255–278.
    • (2009) Pharmacol Ther , vol.123 , pp. 255-278
    • Porter, K.E.1    Turner, N.A.2
  • 29
    • 57849107130 scopus 로고    scopus 로고
    • Signaling to gene expression: calcium, calcineurin and NFAT
    • Rao A. (2009) Signaling to gene expression: calcium, calcineurin and NFAT. Nat Immunol 10: 3–5.
    • (2009) Nat Immunol , vol.10 , pp. 3-5
    • Rao, A.1
  • 31
    • 0036793133 scopus 로고    scopus 로고
    • Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes
    • Santana L.F. Chase E.G. Votaw V.S. Nelson M.T. Greven R. (2002) Functional coupling of calcineurin and protein kinase A in mouse ventricular myocytes. J Physiol 544: 57–69.
    • (2002) J Physiol , vol.544 , pp. 57-69
    • Santana, L.F.1    Chase, E.G.2    Votaw, V.S.3    Nelson, M.T.4    Greven, R.5
  • 33
    • 0035968265 scopus 로고    scopus 로고
    • Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2+ signals by enhancing Ca2+ uptake into the endoplasmic reticulum and mitochondria
    • Smaili S.S. Stellato K.A. Burnett P. Thomas A.P. Gaspers L.D. (2001) Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2+ signals by enhancing Ca2+ uptake into the endoplasmic reticulum and mitochondria. J Biol Chem 276: 23329–23340.
    • (2001) J Biol Chem , vol.276 , pp. 23329-23340
    • Smaili, S.S.1    Stellato, K.A.2    Burnett, P.3    Thomas, A.P.4    Gaspers, L.D.5
  • 34
    • 57749203355 scopus 로고    scopus 로고
    • Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin
    • Tan W.Q. Wang J.X. Lin Z.Q. Li Y.R. Lin Y. Li P.F. (2008) Novel cardiac apoptotic pathway: the dephosphorylation of apoptosis repressor with caspase recruitment domain by calcineurin. Circulation 118: 2268–2276.
    • (2008) Circulation , vol.118 , pp. 2268-2276
    • Tan, W.Q.1    Wang, J.X.2    Lin, Z.Q.3    Li, Y.R.4    Lin, Y.5    Li, P.F.6
  • 35
    • 0029662015 scopus 로고    scopus 로고
    • Intracellular Ca2+ modulation by angiotensin II and endothelin-1 in cardiomyocytes and fibroblasts from hypertrophied hearts of spontaneously hypertensive rats
    • Touyz R.M. Fareh J. Thibault G. Schiffrin E.L. (1996 a) Intracellular Ca2+ modulation by angiotensin II and endothelin-1 in cardiomyocytes and fibroblasts from hypertrophied hearts of spontaneously hypertensive rats. Hypertension 28: 797–805.
    • (1996) Hypertension , vol.28 , pp. 797-805
    • Touyz, R.M.1    Fareh, J.2    Thibault, G.3    Schiffrin, E.L.4
  • 36
    • 0029876291 scopus 로고    scopus 로고
    • Cytosolic calcium changes induced by angiotensin II in neonatal rat atrial and ventricular cardiomyocytes are mediated via angiotensin II subtype 1 receptors
    • Touyz R.M. Sventek P. Larivière R. Thibault G. Fareh J. Reudelhuber T. et al. (1996 b) Cytosolic calcium changes induced by angiotensin II in neonatal rat atrial and ventricular cardiomyocytes are mediated via angiotensin II subtype 1 receptors. Hypertension 27: 1090–1096.
    • (1996) Hypertension , vol.27 , pp. 1090-1096
    • Touyz, R.M.1    Sventek, P.2    Larivière, R.3    Thibault, G.4    Fareh, J.5    Reudelhuber, T.6
  • 37
    • 0345257216 scopus 로고    scopus 로고
    • Modulation of vascular smooth muscle cell growth by magnesium-role of mitogen-activated protein kinases
    • Touyz R.M. Yao G. (2003) Modulation of vascular smooth muscle cell growth by magnesium-role of mitogen-activated protein kinases. J Cell Physiol 197: 326–335.
    • (2003) J Cell Physiol , vol.197 , pp. 326-335
    • Touyz, R.M.1    Yao, G.2
  • 38
    • 53149101690 scopus 로고    scopus 로고
    • Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus
    • Wang S.S. Chou N.K. Chi N.H. Wu I.H. Chen Y.S. Yu H.Y. et al. (2008) Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus. Transplant Proc 40: 2607–2608.
    • (2008) Transplant Proc , vol.40 , pp. 2607-2608
    • Wang, S.S.1    Chou, N.K.2    Chi, N.H.3    Wu, I.H.4    Chen, Y.S.5    Yu, H.Y.6
  • 39
    • 34548695952 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in heart development and diseases
    • Wang Y. (2007) Mitogen-activated protein kinases in heart development and diseases. Circulation 116: 1413–1423.
    • (2007) Circulation , vol.116 , pp. 1413-1423
    • Wang, Y.1
  • 40
    • 20744457904 scopus 로고    scopus 로고
    • Conversion from cyclosporine microemulsion to tacrolimus-based immunoprophylaxis improves cholesterol profile in heart transplant recipients with treated but persistent dyslipidemia: the Canadian multicentre randomized trial of tacrolimus vs cyclosporine microemulsion
    • White M. Haddad H. Leblanc M.H. Giannetti N. Pflugfelder P. Davies R. et al. (2005) Conversion from cyclosporine microemulsion to tacrolimus-based immunoprophylaxis improves cholesterol profile in heart transplant recipients with treated but persistent dyslipidemia: the Canadian multicentre randomized trial of tacrolimus vs cyclosporine microemulsion. J Heart Lung Transplant 24: 798–809.
    • (2005) J Heart Lung Transplant , vol.24 , pp. 798-809
    • White, M.1    Haddad, H.2    Leblanc, M.H.3    Giannetti, N.4    Pflugfelder, P.5    Davies, R.6
  • 41
    • 33749125866 scopus 로고    scopus 로고
    • Subclinical inflammation and prothrombotic state in heart transplant recipients: impact of cyclosporin microemulsion vs. tacrolimus
    • White M. Ross H. Haddad H. LeBlanc M.H. Racine N. Pflugfelder P. et al. (2006) Subclinical inflammation and prothrombotic state in heart transplant recipients: impact of cyclosporin microemulsion vs. tacrolimus. Transplantation 82: 763–770.
    • (2006) Transplantation , vol.82 , pp. 763-770
    • White, M.1    Ross, H.2    Haddad, H.3    LeBlanc, M.H.4    Racine, N.5    Pflugfelder, P.6
  • 43
    • 0037439652 scopus 로고    scopus 로고
    • Preconditioning with cyclosporine A or FK 506 differentially regulates mitogen-activated protein kinase expression in rat kidneys with ischemia / reperfusion injury
    • Yang C.W. Ahn H.J. Jung J.Y. Kim W.Y. Li C. Choi B.S. et al. (2003) Preconditioning with cyclosporine A or FK 506 differentially regulates mitogen-activated protein kinase expression in rat kidneys with ischemia / reperfusion injury. Transplantation 75: 20–24.
    • (2003) Transplantation , vol.75 , pp. 20-24
    • Yang, C.W.1    Ahn, H.J.2    Jung, J.Y.3    Kim, W.Y.4    Li, C.5    Choi, B.S.6
  • 44
    • 58149166707 scopus 로고    scopus 로고
    • Tacrolimus versus cyclosporine microemulsion for heart transplant recipients: a meta-analysis
    • Ye F. Ying-Bin X. Yu-Guo W. Hetzer R. (2009) Tacrolimus versus cyclosporine microemulsion for heart transplant recipients: a meta-analysis. J Heart Lung Transplant 28: 58–66.
    • (2009) J Heart Lung Transplant , vol.28 , pp. 58-66
    • Ye, F.1    Ying-Bin, X.2    Yu-Guo, W.3    Hetzer, R.4
  • 45
    • 0036162159 scopus 로고    scopus 로고
    • Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy
    • Zhang W. (2002) Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy. Cardiovasc Res 53: 294–303.
    • (2002) Cardiovasc Res , vol.53 , pp. 294-303
    • Zhang, W.1
  • 46
    • 33847207513 scopus 로고    scopus 로고
    • CardioSignal: a database of transcriptional regulation in cardiac development and hypertrophy
    • Zhen Y. Wang Y. Zhang W. Zhou C. Hui R. (2007) CardioSignal: a database of transcriptional regulation in cardiac development and hypertrophy. Int J Cardiol 116: 338–347.
    • (2007) Int J Cardiol , vol.116 , pp. 338-347
    • Zhen, Y.1    Wang, Y.2    Zhang, W.3    Zhou, C.4    Hui, R.5


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