Microcrystalline cellulose, a direct compression binder in a quality by design environment - A review

International Journal of Pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 64-72

  Thoorens, Gregory ^a,b   Krier, Fabrice ^a   Leclercq, Bruno ^b   Carlin, Brian ^c   Evrard, Brigitte ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b FMC Health and Nutrition   (Belgium)

^c FMC Health and Nutrition   (United States)

Author keywords

Binder; Critical material attributes; Direct compression; Microcrystalline cellulose; Quality by design; Tablets

Indexed keywords

MICROCRYSTALLINE CELLULOSE; CELLULOSE; EXCIPIENT; TABLET;

BIOMASS PRODUCTION; BULK DENSITY; CRYSTALLIZATION; DISSOLUTION; DRUG DOSAGE FORM; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG QUALITY; DRUG SOLUBILITY; DRUG STORAGE; ECONOMIC ASPECT; HUMIDITY; HYDROGEN BOND; MOISTURE; MORPHOLOGY; PARTICLE SIZE; PHARMACOLOGICAL PARAMETERS; PHYSICAL PARAMETERS; POLYMERIZATION; PRIORITY JOURNAL; REVIEW; SPRAY DRYING; SURFACE PROPERTY; TABLET COMPRESSION; TABLET DISINTEGRATION; TABLET FRIABILITY; TABLET HARDNESS; TABLET POROSITY; TABLET PROPERTY; TENSILE STRENGTH; CHEMISTRY; DRUG FORMULATION; PROCEDURES; QUALITY CONTROL; TABLET;

CELLULOSE; DRUG COMPOUNDING; EXCIPIENTS; QUALITY CONTROL; TABLETS;

EID: 84903974120     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.06.055     Document Type: Review

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