-
1
-
-
77958470619
-
Gastrointestinal stromal tumors: Review on morphology, molecular pathology, diagnostics, prognosis and treatment options
-
Paral J, Slaninka I, Kalabova H, Hadzi-Nikolov D. Gastrointestinal stromal tumors: review on morphology, molecular pathology, diagnostics, prognosis and treatment options. Acta Gastroenterol Belg 2010;73: 349-359.
-
(2010)
Acta Gastroenterol Belg
, vol.73
, pp. 349-359
-
-
Paral, J.1
Slaninka, I.2
Kalabova, H.3
Hadzi-Nikolov, D.4
-
2
-
-
0035890740
-
KIT activation is a ubiquitous feature of gastrointestinal stromal tumors
-
Rubin BP, Singer S, Tsao C, Duensing A, Lux ML, Ruiz R, Hibbard MK, Chen CJ, Xiao S, Tuveson DA, Demetri GD, Fletcher CD, Fletcher JA. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 2001;61: 8118-8121. (Pubitemid 33091601)
-
(2001)
Cancer Research
, vol.61
, Issue.22
, pp. 8118-8121
-
-
Rubin, B.P.1
Singer, S.2
Tsao, C.3
Duensing, A.4
Lux, M.L.5
Ruiz, R.6
Hibbard, M.K.7
Chen, C.-J.8
Xiao, S.9
Tuveson, D.A.10
Demetri, G.D.11
Fletcher, C.D.M.12
Fletcher, J.A.13
-
3
-
-
80855139422
-
Adjuvant imatinib therapy for gastrointestinal stromal tumors
-
Pisters PW, Colombo C. Adjuvant imatinib therapy for gastrointestinal stromal tumors. J Surg Oncol 2011;104: 896-900.
-
(2011)
J Surg Oncol
, vol.104
, pp. 896-900
-
-
Pisters, P.W.1
Colombo, C.2
-
4
-
-
77949535841
-
Pharmacological management of gastrointestinal stromal tumours: An update on the role of sunitinib
-
Blay JY. Pharmacological management of gastrointestinal stromal tumours: an update on the role of sunitinib. Ann Oncol 2010;21: 208-215.
-
(2010)
Ann Oncol
, vol.21
, pp. 208-215
-
-
Blay, J.Y.1
-
5
-
-
84872561751
-
Understanding rechallenge and resistance in the tyrosine kinase inhibitor era: Imatinib in gastrointestinal stromal tumor
-
Epub 2012 Jul 3
-
Agulnik M, Giel JL. Understanding rechallenge and resistance in the tyrosine kinase inhibitor era: imatinib in gastrointestinal stromal tumor. Am J Clin Oncol. Epub 2012 Jul 3.
-
Am J Clin Oncol
-
-
Agulnik, M.1
Giel, J.L.2
-
6
-
-
84858179982
-
KRAS and BRAFmutations predict primary resistance to imatinib in gastrointestinal stromal tumors
-
Miranda C, Nucifora M, Molinari F, Conca E, Anania MC, Bordoni A, Saletti, P, Mazzucchelli L, Pilotti S, Pierotti MA, Tamborini E, Greco A, Frattini M. KRAS and BRAFmutations predict primary resistance to imatinib in gastrointestinal stromal tumors. Clin Cancer Res 2012;18: 1769-1776.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1769-1776
-
-
Miranda, C.1
Nucifora, M.2
Molinari, F.3
Conca, E.4
Anania, M.C.5
Bordoni, A.6
Saletti, P.7
Mazzucchelli, L.8
Pilotti, S.9
Pierotti, M.A.10
Tamborini, E.11
Greco, A.12
Frattini, M.13
-
7
-
-
77957943127
-
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours
-
Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL. ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature 2010;467: 849-853.
-
(2010)
Nature
, vol.467
, pp. 849-853
-
-
Chi, P.1
Chen, Y.2
Zhang, L.3
Guo, X.4
Wongvipat, J.5
Shamu, T.6
Fletcher, J.A.7
Dewell, S.8
Maki, R.G.9
Zheng, D.10
Antonescu, C.R.11
Allis, C.D.12
Sawyers, C.L.13
-
8
-
-
84859402717
-
MAPKAP kinase 2 overexpression influences prognosis in gastrointestinal stromal tumors and associates with copy number variations on chromosome 1 and expression of p38 MAP kinase and ETV1
-
Birner P, Beer A, Vinatzer U, Stary S, Hoftberger R, Nirtl N, Wrba F, Streubel B, Schoppmann SF. MAPKAP kinase 2 overexpression influences prognosis in gastrointestinal stromal tumors and associates with copy number variations on chromosome 1 and expression of p38 MAP kinase and ETV1. Clin Cancer Res 2012;18: 1879-1887.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1879-1887
-
-
Birner, P.1
Beer, A.2
Vinatzer, U.3
Stary, S.4
Hoftberger, R.5
Nirtl, N.6
Wrba, F.7
Streubel, B.8
Schoppmann, S.F.9
-
9
-
-
78751532247
-
ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicua
-
Dissanayake K, Toth R, Blakey J, Olsson O, Campbell DG, Prescott AR, Mac Kintosh C. ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicua. Biochem J 2011;433: 515-525.
-
(2011)
Biochem J
, vol.433
, pp. 515-525
-
-
Dissanayake, K.1
Toth, R.2
Blakey, J.3
Olsson, O.4
Campbell, D.G.5
Prescott, A.R.6
Mac Kintosh, C.7
-
10
-
-
79958195843
-
Gene regulation by MAPK substrate competition
-
Kim Y, Andreu MJ, Lim B, Chung K, Terayama M, Jimenez G, Berg CA, Lu H, Shvartsman SY. Gene regulation by MAPK substrate competition. Dev Cell 2011;20: 880-887.
-
(2011)
Dev Cell
, vol.20
, pp. 880-887
-
-
Kim, Y.1
Andreu, M.J.2
Lim, B.3
Chung, K.4
Terayama, M.5
Jimenez, G.6
Berg, C.A.7
Lu, H.8
Shvartsman, S.Y.9
-
11
-
-
33846946102
-
A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling
-
Astigarraga S, Grossman R, Diaz-Delfin J, Caelles C, Paroush Z, Jimenez G. A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling. Embo J 2007;26: 668-677.
-
(2007)
Embo J
, vol.26
, pp. 668-677
-
-
Astigarraga, S.1
Grossman, R.2
Diaz-Delfin, J.3
Caelles, C.4
Paroush, Z.5
Jimenez, G.6
-
12
-
-
77649190430
-
MAPK substrate competition integrates patterning signals in the Drosophila embryo
-
Kim Y, Coppey M, Grossman R, Ajuria L, Jimenez G, Paroush Z, Shvartsman SY. MAPK substrate competition integrates patterning signals in the Drosophila embryo. Curr Biol 2010;20: 446-451.
-
(2010)
Curr Biol
, vol.20
, pp. 446-451
-
-
Kim, Y.1
Coppey, M.2
Grossman, R.3
Ajuria, L.4
Jimenez, G.5
Paroush, Z.6
Shvartsman, S.Y.7
-
13
-
-
2542520755
-
Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs)
-
DOI 10.1038/sj.onc.1207525
-
Duensing A, Medeiros F, Mc Conarty B, Joseph NE, Panigrahy D, Singer S, Fletcher CD, Demetri GD, Fletcher JA. Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs). Oncogene 2004;23: 3999-4006. (Pubitemid 38747928)
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 3999-4006
-
-
Duensing, A.1
Medeiros, F.2
McConarty, B.3
Joseph, N.E.4
Panigrahy, D.5
Singer, S.6
Fletcher, C.D.M.7
Demetri, G.D.8
Fletcher, J.A.9
-
14
-
-
0036301722
-
Diagnosis of gastrointestinal stromal tumors: A consensus approach
-
DOI 10.1053/hupa.2002.123545
-
Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, Miettinen M, O'Leary TJ, Remotti H, Rubin BP, Shmookler B, Sobin LH, Weiss SW. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol 2002;33: 459-465. (Pubitemid 34747864)
-
(2002)
Human Pathology
, vol.33
, Issue.5
, pp. 459-465
-
-
Fletcher, C.D.M.1
Berman, J.J.2
Corless, C.3
Gorstein, F.4
Lasota, J.5
Longley B.Jack6
Miettinen, M.7
O'Leary, T.J.8
Remotti, H.9
Rubin, B.P.10
Shmookler, B.11
Sobin, L.H.12
Weiss, S.W.13
-
15
-
-
33750618188
-
Gastrointestinal stromal tumors: Pathology and prognosis at different sites
-
DOI 10.1053/j.semdp.2006.09.001, PII S0740257006001432
-
Miettinen M, Lasota J. Gastrointestinal stromal tumors: pathology and prognosis at different sites. Semin Diagn Pathol 2006;23: 70-83. (Pubitemid 44692418)
-
(2006)
Seminars in Diagnostic Pathology
, vol.23
, Issue.2
, pp. 70-83
-
-
Miettinen, M.1
Lasota, J.2
-
16
-
-
84878424169
-
Downregulation of phosphatidylethanolamine binding protein 1 associates with clinical risk factors in gastrointestinal stromal tumors, but not with activation of the RAF-1-MEK-ETV1 pathway
-
Schoppmann SF, Beer A, Nirtl N, Ba-Ssalamah A, Brodowicz T, Streubel B, Birner P. Downregulation of phosphatidylethanolamine binding protein 1 associates with clinical risk factors in gastrointestinal stromal tumors, but not with activation of the RAF-1-MEK-ETV1 pathway. Cancer Lett 2013;335: 26-30.
-
(2013)
Cancer Lett
, vol.335
, pp. 26-30
-
-
Schoppmann, S.F.1
Beer, A.2
Nirtl, N.3
Ba-Ssalamah, A.4
Brodowicz, T.5
Streubel, B.6
Birner, P.7
-
17
-
-
84864480217
-
Expression of podoplanin is a rare event in sporadic gastrointestinal stromal tumors and does not influence prognosis
-
Schoppmann SF, Berghoff AS, Jesch B, Zacherl J, Nirtl N, Jomrich G, Maroske F, Streubel B, Mesteri I, Birner P. Expression of podoplanin is a rare event in sporadic gastrointestinal stromal tumors and does not influence prognosis. Future Oncol 2012;8: 859-866.
-
(2012)
Future Oncol
, vol.8
, pp. 859-866
-
-
Schoppmann, S.F.1
Berghoff, A.S.2
Jesch, B.3
Zacherl, J.4
Nirtl, N.5
Jomrich, G.6
Maroske, F.7
Streubel, B.8
Mesteri, I.9
Birner, P.10
-
18
-
-
84886430852
-
Novel clinically relevant genes in gastrointestinal stromal tumors identified by exome sequencing
-
Schoppmann SF, Vinatzer U, Popitsch N, Mittlbock M, Liebmann- Reindl S, Jomrich G, Streubel B, Birner P. Novel clinically relevant genes in gastrointestinal stromal tumors identified by exome sequencing. Clin Cancer Res 2013;19: 5329-5339.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 5329-5339
-
-
Schoppmann, S.F.1
Vinatzer, U.2
Popitsch, N.3
Mittlbock, M.4
Liebmann- Reindl, S.5
Jomrich, G.6
Streubel, B.7
Birner, P.8
-
19
-
-
0343986271
-
Relief of gene repression by Torso RTK signaling: Role of capicua in Drosophila terminal and dorsoventral patterning
-
Jimenez G, Guichet A, Ephrussi A, Casanova J. Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning. Genes Dev 2000;14: 224-231. (Pubitemid 30070987)
-
(2000)
Genes and Development
, vol.14
, Issue.2
, pp. 224-231
-
-
Jimenez, G.1
Guichet, A.2
Ephrussi, A.3
Casanova, J.4
-
20
-
-
84861209129
-
The Capicua repressor - A general sensor of RTKsignaling indevelopment anddisease
-
Jimenez G, Shvartsman SY, Paroush Z.The Capicua repressor - a general sensor of RTKsignaling indevelopment anddisease. J Cell Sci 2012;125: 1383-1391.
-
(2012)
J Cell Sci
, vol.125
, pp. 1383-1391
-
-
Jimenez, G.1
Shvartsman, S.Y.2
Paroush, Z.3
-
21
-
-
34047276449
-
Capicua Regulates Cell Proliferation Downstream of the Receptor Tyrosine Kinase/Ras Signaling Pathway
-
DOI 10.1016/j.cub.2007.03.023, PII S0960982207011256
-
Tseng AS, Tapon N, Kanda H, Cigizoglu S, Edelmann L, Pellock B, White K, Hariharan IK. Capicua regulates cell proliferation downstreamof the receptor tyrosine kinase/ras signaling pathway. Curr Biol 2007;17: 728-733. (Pubitemid 46552255)
-
(2007)
Current Biology
, vol.17
, Issue.8
, pp. 728-733
-
-
Tseng, A.-S.K.1
Tapon, N.2
Kanda, H.3
Cigizoglu, S.4
Edelmann, L.5
Pellock, B.6
White, K.7
Hariharan, I.K.8
-
22
-
-
22144489134
-
CIC, a gene involved in cerebellar development and ErbB signaling, is significantly expressed in medulloblastomas
-
DOI 10.1007/s11060-004-4598-2
-
Lee CJ, Chan WI, Scotting PJ. CIC, a gene involved in cerebellar development and Erb B signaling, is significantly expressed in medulloblastomas. J Neurooncol 2005;73: 101-108. (Pubitemid 40974029)
-
(2005)
Journal of Neuro-Oncology
, vol.73
, Issue.2
, pp. 101-108
-
-
Lee, C.-J.1
Chan, W.-I.2
Scotting, P.J.3
-
23
-
-
80052608062
-
Mutations in CIC and FUBP1 contribute to human oligodendroglioma
-
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, Mc Lendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, Yan H, Papadopoulos N, Kinzler KW. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science 2011;333: 1453-1455.
-
(2011)
Science
, vol.333
, pp. 1453-1455
-
-
Bettegowda, C.1
Agrawal, N.2
Jiao, Y.3
Sausen, M.4
Wood, L.D.5
Hruban, R.H.6
Rodriguez, F.J.7
Cahill, D.P.8
Mc Lendon, R.9
Riggins, G.10
Velculescu, V.E.11
Oba-Shinjo, S.M.12
Marie, S.K.13
Vogelstein, B.14
Bigner, D.15
Yan, H.16
Papadopoulos, N.17
Kinzler, K.W.18
-
24
-
-
33745283008
-
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation
-
DOI 10.1093/hmg/ddl136
-
Kawamura-Saito M, Yamazaki Y, Kaneko, K, Kawaguchi N, Kanda H, Mukai H, Gotoh T, Motoi T, Fukayama M, Aburatani H, Takizawa T, Nakamura T. Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation. Hum Mol Genet 2006;15: 2125-2137. (Pubitemid 43923402)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.13
, pp. 2125-2137
-
-
Kawamura-Saito, M.1
Yamazaki, Y.2
Kaneko, K.3
Kawaguchi, N.4
Kanda, H.5
Mukai, H.6
Gotoh, T.7
Motoi, T.8
Fukayama, M.9
Aburatani, H.10
Takizawa, T.11
Nakamura, T.12
-
25
-
-
0029118034
-
Molecular characterization of the ets-related human transcription factor ER81
-
Monte D, Coutte L, Baert JL, Angeli I, Stehelin D, de Launoit Y. Molecular characterization of the ets-related human transcription factor ER81. Oncogene 1995;11: 771-779.
-
(1995)
Oncogene
, vol.11
, pp. 771-779
-
-
Monte, D.1
Coutte, L.2
Baert, J.L.3
Angeli, I.4
Stehelin, D.5
De Launoit, Y.6
-
26
-
-
0028903089
-
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1
-
Jeon IS, Davis JN, Braun BS, Sublett JE, Roussel MF, Denny CT, Shapiro DN. A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. Oncogene 1995;10: 1229-1234.
-
(1995)
Oncogene
, vol.10
, pp. 1229-1234
-
-
Jeon, I.S.1
Davis, J.N.2
Braun, B.S.3
Sublett, J.E.4
Roussel, M.F.5
Denny, C.T.6
Shapiro, D.N.7
-
27
-
-
27344451557
-
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
-
DOI 10.1126/science.1117679
-
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 2005;310: 644-648. (Pubitemid 41528150)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 644-648
-
-
Tomlins, S.A.1
Rhodes, D.R.2
Perner, S.3
Dhanasekaran, S.M.4
Mehra, R.5
Sun, X.-W.6
Varambally, S.7
Cao, X.8
Tchinda, J.9
Kuefer, R.10
Lee, C.11
Montie, J.E.12
Shah, R.B.13
Pienta, K.J.14
Rubin, M.A.15
Chinnaiyan, A.M.16
-
28
-
-
77950193693
-
An oncogenic role for ETV1 in melanoma
-
Jane-Valbuena J, Widlund HR, Perner S, Johnson LA, Dibner AC, Lin WM, Baker AC, Nazarian RM, Vijayendran KG, Sellers WR, Hahn WC, Duncan LM, Rubin MA, Fisher DE, Garraway LA. An oncogenic role for ETV1 in melanoma. Cancer Res 2010;70: 2075-2084.
-
(2010)
Cancer Res
, vol.70
, pp. 2075-2084
-
-
Jane-Valbuena, J.1
Widlund, H.R.2
Perner, S.3
Johnson, L.A.4
Dibner, A.C.5
Lin, W.M.6
Baker, A.C.7
Nazarian, R.M.8
Vijayendran, K.G.9
Sellers, W.R.10
Hahn, W.C.11
Duncan, L.M.12
Rubin, M.A.13
Fisher, D.E.14
Garraway, L.A.15
-
29
-
-
20344393896
-
Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation
-
DOI 10.1158/1078-0432.CCR-04-2245
-
Antonescu CR, Besmer P, Guo T, Arkun K, Hom G, Koryotowski B, Leversha MA, Jeffrey PD, Desantis D, Singer S, Brennan MF, Maki RG, De Matteo RP. Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res 2005;11: 4182-4190. (Pubitemid 40791584)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.11
, pp. 4182-4190
-
-
Antonescu, C.R.1
Besmer, P.2
Guo, T.3
Arkun, K.4
Hom, G.5
Koryotowski, B.6
Leversha, M.A.7
Jeffrey, P.D.8
Desantis, D.9
Singer, S.10
Brennan, M.F.11
Maki, R.G.12
DeMatteo, R.P.13
-
30
-
-
0031963488
-
Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity
-
PII S01654B0897NO010
-
Knuutila S, Armengol G, Bjorkqvist AM, el-Rifai W, Larramendy ML, Monni O, Szymanska J. Comparative genomic hybridization study on pooled DNAs from tumors of one clinical-pathological entity. Cancer Genet Cytogenet 1998;100: 25-30. (Pubitemid 128766338)
-
(1998)
Cancer Genetics and Cytogenetics
, vol.100
, Issue.1
, pp. 25-30
-
-
Knuutila, S.1
Armengol, G.2
Bjorkqvist, A.-M.3
El-Rifai, W.4
Larramendy, M.L.5
Monni, O.6
Szymanska, J.7
-
31
-
-
34548051808
-
Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: A report of three new cases with mutational analysis and comparative genomic hybridization
-
Agaimy A, Pelz AF, Corless CL, Wunsch PH, Heinrich MC, Hofstaedter F, Dietmaier W, Blanke CD, Wieacker P, Roessner A, Hartmann A, Schneider-Stock R. Epithelioid gastric stromal tumours of the antrum in young females with the Carney triad: a report of three new cases with mutational analysis and comparative genomic hybridization. Oncol Rep 2007;18: 9-15.
-
(2007)
Oncol Rep
, vol.18
, pp. 9-15
-
-
Agaimy, A.1
Pelz, A.F.2
Corless, C.L.3
Wunsch, P.H.4
Heinrich, M.C.5
Hofstaedter, F.6
Dietmaier, W.7
Blanke, C.D.8
Wieacker, P.9
Roessner, A.10
Hartmann, A.11
Schneider-Stock, R.12
|