A new and improved method for the preparation of drug nanosuspension formulations using acoustic mixing technology

International Journal of Pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 10-19

  Leung, Dennis H ^a   Lamberto, David J ^a   Liu, Lina ^a   Kwong, Elizabeth ^b   Nelson, Todd ^a   Rhodes, Timothy ^a   Bak, Annette ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Kwong Eureka Solutions   (Canada)

Author keywords

Formulation; High throughput technologies; Milling; Nanoparticles; Nanotechnology; Particle size

Indexed keywords

EXCIPIENT; NANOPARTICLE; NAPROXEN; NEW DRUG; PHOSPHATIDYLCHOLINE; POLOXAMER; POLYSORBATE 80; POVIDONE; ZIRCONIUM OXIDE; POLYMER; SURFACTANT; SUSPENSION;

ACOUSTIC MIXING; ANALYTIC METHOD; ARTICLE; AUDITORY SYSTEM; DRUG FORMULATION; ELECTRONICS; HIGH THROUGHPUT SCREENING; IN VIVO STUDY; NANOSUSPENSION; NANOTECHNOLOGY; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; SCALE UP; SHEAR STRESS; SUSPENSION; VISCOSITY; ACOUSTICS; CHEMISTRY; COMPUTER SIMULATION; DRUG STABILITY; HYDRODYNAMICS; PROCEDURES;

ACOUSTICS; COMPUTER SIMULATION; DRUG COMPOUNDING; DRUG STABILITY; HYDRODYNAMICS; NANOPARTICLES; NAPROXEN; PARTICLE SIZE; POLYMERS; SURFACE-ACTIVE AGENTS; SUSPENSIONS; VISCOSITY;

EID: 84903841118     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.05.003     Document Type: Article

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