Enhanced efficacy of photodynamic therapy via a sequential targeting protocol

Photochemistry and Photobiology

Volumn 90, Issue 4, 2014, Pages 889-895

  Kessel, David ^a   Reiners, John J ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROLIDE; PHOTOSENSITIZING AGENT; PORPHYRIN; REACTIVE OXYGEN METABOLITE; TALAPORFIN; VERTEPORFIN;

ANIMAL; MITOCHONDRION; MOUSE; PHOTOCHEMOTHERAPY; RADIATION RESPONSE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; MACROLIDES; MICE; MITOCHONDRIA; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PORPHYRINS; REACTIVE OXYGEN SPECIES;

EID: 84903815473     PISSN: 00318655     EISSN: 17511097     Source Type: Journal    
DOI: 10.1111/php.12270     Document Type: Article

References (33)

1. Dougherty, T. J., C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan, and, Q. Peng, (1998) Photodynamic therapy. J. Natl Cancer Inst. 90, 889-905.
2. Agostinis, P., K. Berg, K. A. Cengel, T. H. Foster, A. W. Girotti, S. O. Gollnick, S. M. Hahn, M. R. Hamblin, A. Juzeniene, D. Kessel, M. Korbelik, J. Moan, P. Mroz, D. Nowis, J. Piette, B. C. Wilson, and, J. Golan, (2011) Photodynamic therapy of cancer: An update. CA Cancer J. Clin. 61, 250-281.
3. Trivedi, N. S., (2000) Quantitative analysis of Pc 4 localization in mouse lymphoma (LY-R) cells via double-label confocal fluorescence microscopy. Photochem. Photobiol. 71, 634-639.
4. Lam, M., N. L. Oleinick, and, A. L. Nieminen, (2001) Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. J. Biol. Chem. 276, 47379-47386.
5. Kessel, D., and, J. J. Jr Reiners, (2007) Apoptosis and autophagy after mitochondrial or endoplasmic reticulum photodamage. Photochem. Photobiol. 83, 1024-1028.
6. Usuda, J., K. Azizuddin, S. M. Chiu, and, N. L. Oleinick, (2003) Association between the photodynamic loss of Bcl-2 and the sensitivity to apoptosis caused by phthalocyanine photodynamic therapy. Photochem. Photobiol. 78, 1-8.
7. Peng, T. I., C. J. Chang, M. J. Guo, Y. H. Wang, J. S. Yu, H. Y. Wu, and, M. J. Jou, (2005) Mitochondrion-targeted photosensitizer enhances the photodynamic effect-induced mitochondrial dysfunction and apoptosis. Ann. N. Y. Acad. Sci. 1042, 419-428.
8. Kessel, D., and, N. L. Oleinick, (2010) Photodynamic therapy and cell death pathways. Methods Mol. Biol. 635, 35-46.
9. Saggu, S., H. I. Hung, G. Quiogue, J. J. Lemasters, and, A. L. Nieminen, (2012) Lysosomal signaling enhances mitochondria-mediated photodynamic therapy in A431 cancer cells: Role of iron. Photochem. Photobiol. 88, 461-468.
10. Hung, H. I., J. M. Schwartz, E. N. Maldonado, J. J. Lemasters, and, A. L. Nieminen, (2013) Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy. J. Biol. Chem. 288, 677-686.
11. Reiners, J. J. Jr, J. A. Caruso, P. Mathieu, B. Chelladurai, X. M. Yin, and, D. Kessel, (2002) Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage. Cell Death Differ. 9, 934-944.
12. Reiners, J. J. Jr, M. Kleinman, D. Kessel, P. A. Mathieu, and, J. A. Caruso, (2012) Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization. Free Radic. Biol. Med. 50, 281-294.
13. Stoka, V., B. Turk, S. L. Schendel, T.-H. Kim, T. Cirman, S. J. Snipas, L. M. Ellerby, D. Bredesen, H. Freeze, M. Abrahamson, D. Brommer, S. Krajewski, J. C. Reed, X.-M. Yin, V. Turk, and, G. S. Salvesen, (2001) Lysosomal protease pathways to apoptosis: Cleavage of Bid, not pro-caspases, is the most likely route. J. Biol. Chem. 276, 3149-3157.
14. Korsmeyer, S. J., M. C. Wei, M. Saito, S. Weiler, K. J. Oh, and, P. H. Schlesinger, (2000) Proapoptotic cascade activated by BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c. Cell Death Differ. 7, 1166-1173.
15. Kessel, D., M. Price, J. Caruso, and, J. J. Jr Reiners, (2011) Effects of photodynamic therapy on the endocytic pathway. Photchem. Photobiol. Sci. 10, 491-498.
16. Kessel, D., and, M. Price, (2012) Evaluation of diethyl-3-3-(9,10- anthracenediyl)bis acrylate as a probe for singlet oxygen formation during photodynamic therapy. Photochem. Photobiol. 88, 717-720.
17. Hirayama, T., O. Kensuke, and, H. Nagasawa, (2013) A highly selective turn-on fluorescent probe for iron(II) to visualize labile iron in living cells. Chem. Sci. 4, 1250-1256.
18. Andrzejak, M., M. Price, and, D. Kessel, (2011) Apoptotic and autophagic responses to photodynamic therapy in 1c1c7 murine hepatoma cells. Autophagy 7, 979-984.
19. Price, M., J. J. Reiners, A. M. Santiago, and, D. Kessel, (2009) Monitoring singlet oxygen and hydroxyl radical formation with fluorescent probes during photodynamic therapy. Photochem. Photobiol. 85, 1177-1181.
20. Kessel, D., and, J. J. Jr Reiners, (2012) Light-Activated Pharmaceuticals: Mechanisms and Detection. Isr. J. Chem. 52, 674-680.
21. Kessel, D., J. A. Caruso, and, J. J. Jr Reiners, (2000) Potentiation of photodynamic therapy by ursodeoxycholic acid. Cancer Res. 60, 6985-6988.
22. Kessel, D., Y. Luo, P. Mathieu, and, J. J. Jr Reiners, (2000) Determinants of the apoptotic response to lysosomal photodamage. Photochem. Photobiol. 71, 196-200.
23. Price, M., L. Heilbrun, and, D. Kessel, (2013) Effects of the oxygenation level on formation of different reactive oxygen species during photodynamic therapy. Photochem. Photobiol. 89, 683-686.
24. Bowman, E. J., A. Siebers, and, K. Altendorf, (1988) Bafilomycins: A class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells. Proc. Natl Acad. Sci. USA 85, 7972-7976.
25. Gagliardi, S., M. Rees, and, C. Farina, (1999) Chemistry and structure activity relationships of bafiomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase. Curr. Med. Chem. 6, 1197-1212.
26. Uchiyama, A., J.-S. Kim, K. Kon, H. Jaeschke, K. Ikejima, S. Watanabe, and, J. J. Lemaster, (2008) Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology 48, 1644-1654.
27. Ying, W. L., J. Emerson, M. J. Clarke, and, D. R. Sanadi, (1991) Inhibition of mitochondrial calcium ion transport by an oxo-bridged dinuclear ruthenium ammine complex. Biochemistry 30, 4949-4952.
28. Price, M., S. R. Terlecky, and, D. Kessel, (2009) A role for hydrogen peroxide in the pro-apoptotic effects of photodynamic therapy. Photochem. Photobiol. 85, 1491-1496.
29. Setsukinai, K., Y. Urano, K. Kakinuma, H. J. Majima, and, T. Nagano, (2003) Development of novel fluorescence probes that can reliably detect reactive oxygen species and distinguish specific species. J. Biol. Chem. 278, 3170-3175.
30. Caruso, J. A., P. A. Mathieu, A. Joiakim, B. Leeson, D. Kessel, B. F. Sloane, and, J. J. Jr Reiners, (2004) Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: Influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. Mol. Pharmacol. 65, 1016-1028.
31. Kessel, D., (2011) Inhibition of endocytic processes by photodynamic therapy. Lasers Surg. Med. 43, 542-547.
32. Weyergang, A., K. Berg, O. Kaalhus, Q. Peng, and, P. K. Selbo, (2009) Photodynamic therapy targets the mTOR signaling network in vitro and in vivo. Mol. Pharm. 6, 255-264.
33. Dewaele, M., W. Martinet, N. Rubio, T. Verfaillie, P. A. de Witte, J. Piette, and, P. Agostinis, (2011) Autophagy pathways activated in response to PDT contribute to cell resistance against ROS damage. J. Cell Mol. Med. 15, 1402-1414.