Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 677-686

  Hung, Hsin I ^a   Schwartz, Justin M ^a   Maldonado, Eduardo N ^a   Lemasters, John J ^a,b   Nieminens, Anna Liisa ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAFILOMYCIN; CELL KILLING; CELL LINES; CYTOSOLS; ENDOSOMES; HEAD-AND-NECK CANCER; HUMAN HEAD; INNER MEMBRANES; IRON CHELATORS; IRON RELEASE; IRON TRANSPORTER; IRON UPTAKE; MITOCHONDRIAL DYSFUNCTION; PROTEIN LEVEL; PROTON PUMP; SQUAMOUS CARCINOMA;

CELL CULTURE; CELL DEATH; IRON; PHOTODYNAMIC THERAPY; PHOTOSENSITIZERS;

MITOCHONDRIA;

BAFILOMYCIN; BIOLOGICAL MARKER; IRON BINDING PROTEIN; MITOFERRIN 2; PHTHALOCYANINE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CELL KILLING; CELL MEMBRANE DEPOLARIZATION; CELL TRANSPORT; CELLULAR DISTRIBUTION; CELLULAR SECRETION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG SENSITIVITY; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IRON KINETICS; IRON TRANSPORT; MITOCHONDRIAL MEMBRANE POTENTIAL; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN FUNCTION;

CARCINOMA, SQUAMOUS CELL; CATION TRANSPORT PROTEINS; CELL LINE, TUMOR; CHELATING AGENTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; IRON; LYSOSOMES; MACROLIDES; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MODELS, BIOLOGICAL; PHOTOCHEMOTHERAPY; REACTIVE OXYGEN SPECIES; TIME FACTORS;

EID: 84872069315     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.422667     Document Type: Article

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