Peptide-independent stabilization of MHC class I molecules breaches cellular quality control

Journal of Cell Science

Volumn 127, Issue 13, 2014, Pages 2885-2897

  Hein, Zeynep ^a   Uchtenhagen, Hannes ^b   Abualrous, Esam Tolba ^a   Saini, Sunil Kumar ^a   Janßen, Linda ^a   Hateren, Andy Van ^c   Wiek, Constanze ^d   Hanenberg, Helmut ^d   Momburg, Frank ^e   Achour, Adnane ^b   Elliott, Tim ^c   Springer, Sebastian ^a   Boulanger, Denise ^c  

^a JACOBS UNIVERSITY BREMEN   (Germany)

^b SCIENCE FOR LIFE LABORATORY   (Sweden)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d HEINRICH HEINE UNIVERSITY   (Germany)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Antigen presentation; Endocytosis; ER quality control; Major histocompatibility complex

Indexed keywords

BETA 2 MICROGLOBULIN; DISULFIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; EPITOPE; H2 ANTIGEN; HLA ANTIGEN CLASS 1;

ALPHA HELIX; ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL SURFACE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISULFIDE BOND; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; FIBROBLAST CULTURE; GOLGI COMPLEX; HEAVY CHAIN; LIGHT CHAIN; MOLECULAR DYNAMICS; MOLECULAR STABILITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; QUALITY CONTROL; 3T3 CELL LINE; ANIMAL; C57BL MOUSE; CHEMICAL STRUCTURE; CHEMISTRY; HELA CELL LINE; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PROTEIN SECONDARY STRUCTURE; T LYMPHOCYTE;

3T3 CELLS; ANIMALS; ANTIGEN PRESENTATION; ENDOCYTOSIS; EPITOPES; H-2 ANTIGENS; HELA CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MODELS, MOLECULAR; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; T-LYMPHOCYTES;

EID: 84903786827     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.145334     Document Type: Article

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