Dynamical characterization of two differentially disease associated MHC class i proteins in complex with viral and self-peptides

Journal of Molecular Biology

Volumn 415, Issue 2, 2012, Pages 429-442

  Narzi, Daniele ^a   Becker, Caroline M ^a   Fiorillo, Maria T ^b   Uchanska Ziegler, Barbara ^c   Ziegler, Andreas ^c   Böckmann, Rainer A ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

ankylosing spondylitis; HLA B27; MHC conformational flexibility; molecular dynamics simulation; peptide MHC complex

Indexed keywords

ASPARTIC ACID; EPITOPE; HISTIDINE; HLA B ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE DERIVATIVE; VIRUS PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ANKYLOSING SPONDYLITIS; ANTIGEN PRESENTATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; EFFECTOR CELL; ENTROPY; IMMUNE SYSTEM; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN POLYMORPHISM; PROTEIN STABILITY; RECEPTOR BINDING; SIMULATION;

EID: 84855767247     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.11.021     Document Type: Article

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