Tapasin dependence of major histocompatibility complex class I molecules correlates with their conformational flexibility

FASEB Journal

Volumn 25, Issue 11, 2011, Pages 3989-3998

  Garstka, Malgorzata Anna ^a,f   Fritzsche, Susanne ^a   Lenart, Izabela ^b   Hein, Zeynep ^a   Jankevicius, Gytis ^a   Boyle, Louise H ^c   Elliott, Tim ^d   Trowsdale, John ^c   Antoniou, Antony N ^b   Zacharias, Martin ^e   Springer, Sebastian ^a  

^a JACOBS UNIVERSITY BREMEN   (Germany)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Ligand binding; Natively unstructured proteins; Peptide binding; Quality control

Indexed keywords

4 ACETAMIDO 4 MALEIMIDYLSTILBENE 2,2 DISULFONIC ACID; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; N ACETYL BETA GLUCOSAMINIDASE; PEPTIDE; SULFONIC ACID DERIVATIVE; TAPASIN; TRICHLOROACETIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CELL MEMBRANE; COMPUTER MODEL; CYTOTOXIC T LYMPHOCYTE; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOPRECIPITATION; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; POINT MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; THERMOSTABILITY;

CELL LINE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA-B44 ANTIGEN; HUMANS; MEMBRANE TRANSPORT PROTEINS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 80355148422     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.11-190249     Document Type: Article

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