Curcumin-and natural extract-loaded nanofibres for potential treatment of lung and breast cancer: In vitro efficacy evaluation

Journal of Biomaterials Science, Polymer Edition

Volumn 25, Issue 10, 2014, Pages 985-998

  Sridhar, Radhakrishnan ^a   Ravanan, Swamy ^b   Venugopal, Jayarama Reddy ^a   Sundarrajan, Subramanian ^a   Pliszka, Damian ^a   Sivasubramanian, S ^c   Gunasekaran, P ^c   Prabhakaran, Mohana ^c   Madhaiyan, Kalaipriya ^a   Sahayaraj, Arockia ^b   Lim, Keith Hsiu Chin ^d   Ramakrishna, Seeram ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b BHARATHIDASAN UNIVERSITY   (India)

^c Institute of Preventive Medicine   (India)

^d National University Cancer Institute   (Singapore)

Author keywords

anti cancer; drug delivery; Nanofibre; natural ingredient; PCL

Indexed keywords

BIOLOGICAL ORGANS; CELL CULTURE; DISEASES; DRUG DELIVERY; POLYCAPROLACTONE; SCANNING ELECTRON MICROSCOPY; TENSILE TESTING;

ACTIVE PHARMACEUTICAL INGREDIENTS; ANTI-CANCER; ANTICANCER ACTIVITIES; HUMAN BREAST CANCER; NANOFIBRE; NATURAL INGREDIENTS; PCL; SUSTAINED DRUG RELEASE;

NANOFIBERS;

ALOE VERA EXTRACT; CISPLATIN; CURCUMIN; NANOFIBER; POLYCAPROLACTONE; ANTINEOPLASTIC AGENT; DRUG CARRIER; PLANT EXTRACT; POLYESTER;

ALOE VERA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELUTING STENT; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; LUNG CANCER; NANOENCAPSULATION; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; BREAST NEOPLASMS; CHEMISTRY; LUNG NEOPLASMS; PATHOLOGY; TUMOR CELL LINE;

ALOE VERA;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CURCUMIN; DRUG CARRIERS; HUMANS; LUNG NEOPLASMS; NANOFIBERS; PLANT EXTRACTS; POLYESTERS;

EID: 84903786581     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1080/09205063.2014.917039     Document Type: Article

References (52)

1. Stefanini GG, Holmes DR Jr. Drug-eluting coronary-artery stents. N. Engl. J. Med. 2013; 368: 254-265. 10.1056/NEJMra1210816
2. Zhang Z, Mei L, Feng SS. Paclitaxel drug delivery systems. Expert Opin. Drug Deliv. 2013; 10: 325-340. 10.1517/17425247.2013.752354
3. Schnorr B, Albrecht T. Drug-coated balloons and their place in treating peripheral arterial disease. Expert Rev. Med. Devices. 2013; 10: 105-114. 10.1586/erd.12.67
4. Wöhrle J. Drug-coated balloons for coronary and peripheral interventional procedures. Curr. Cardiol. Rep. 2012; 14: 635-641. 10.1007/s11886-012-0290-x
5. Ju MH, Rodríguez HE. Standard balloon angioplasty versus angioplasty with paclitaxel-eluting balloons for femoropopliteal artery stenosis. J. Cardiovasc. Surg. (Torino). 2012; 53: 459-463.
6. Puranik AS, Dawson ER, Peppas NA. Recent advances in drug eluting stents. Int. J. Pharm. 2013; 441: 665-679. 10.1016/j.ijpharm.2012.10.029
7. Seidlitz A, Nagel S, Semmling B, Sternberg K, Kroemer HK, Weitschies W. In vitro dissolution testing of drug-eluting stents. Curr. Pharm. Biotechnol. 2013; 14: 67-75.
8. Luk A, Junnarkar G. Critical challenges to the design of drug-eluting medical devices. Ther. Deliv. 2013; 4: 471-477. 10.4155/tde.13.17
9. Wolinsky JB, Colson YL, Grinstaff MW. Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J. Controlled Release. 2012; 159: 14-26. 10.1016/j.jconrel.2011.11.031
10. Wischke C, Lendlein A. Designing multifunctional polymers for cardiovascular implants. Clin. Hemorheol. Microcirc. 2011; 49: 347-355.
11. Weiner AL, Gilger BC. Advancements in ocular drug delivery. Vet. Ophthalmol. 2010; 13: 395-406. 10.1111/vop.2010.13.issue-6
12. Onuma Y, Ormiston J, Serruys PW. Bioresorbable scaffold technologies. Circ. J. 2011; 75: 509-520. 10.1253/circj.CJ-10-1135
13. Lansky AJ, Costa RA, Mintz GS, Tsuchiya Y, Midei M, Cox DA, OShaughnessy C, Applegate RA, Cannon LA, Mooney M, Farah A, Tannenbaum MA, Yakubov S, Kereiakes DJ, Wong SC, Kaplan B, Cristea E, Stone GW, Leon MB, Knopf WD, ONeill WW,. for the DELIVER Clinical Trial Investigators. Non-polymer-based paclitaxel-coated coronary stents for the treatment of patients with de novo coronary lesions: Angiographic follow-up of the DELIVER clinical trial. Circulation. 2004; 109: 1948-1954. 10.1161/01.CIR.0000127129.94129.6F
14. Lagerqvist B, James SK, Stenestrand U, Lindbäck J, Nilsson T, Wallentin L, SCAAR Study Group. Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden. N. Engl. J. Med. 2007; 356: 1009-1019. 10.1056/NEJMoa067722
15. Pfisterer M, Brunner-La Rocca HP, Buser PT, Rickenbacher P, Hunziker P, Mueller C, Jeger R, Bader F, Osswald S, Kaiser C, BASKET-LATE Investigators. Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: An observational study of drug-eluting versus bare-metal stents. J. Am. Coll. Cardiol. 2006; 48 (12): 2584-2591. 10.1016/j.jacc.2006.10. 026
16. Daemen J, Wenaweser P, Tsuchida K, Abrecht L, Vaina S, Morger C, Kukreja N, Jüni P, Sianos G, Hellige G, van Domburg RT, Hess OM, Boersma E, Meier B, Windecker S, Serruys PW. Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. Lancet. 2007; 369: 667-678. 10.1016/S0140-6736(07)60314-6
17. Khan W, Farah S, Domb AJ. Drug eluting stents: developments and current status. J. Controlled Release. 2012; 161: 703-712. 10.1016/j.jconrel.2012.02.010
18. Park KW, Lee JM, Kang SH, Ahn HS, Yang HM, Lee HY, Kang HJ, Koo BK, Cho J, Gwon HC, Lee SY, Chae IH, Youn TJ, Chae JK, Han KR, Yu CW, Kim HS. Safety and efficacy of second-generation everolimus-eluting Xience V stents versus zotarolimus-eluting resolute stents in real-world practice: patient-related and stent-related outcomes from the multicenter prospective EXCELLENT and RESOLUTE-Korea registries. J. Am. Coll. Cardiol. 2013; 61: 536-544. 10.1016/j.jacc.2012.11.015
19. Chen KY, Rha SW, Wang L, Li YJ, Li GP, Poddar KL, Park JY, Choi CU, Park CG, Seo HS, Oh DJ, Jeong MH, Ahn YK, Hong TJ, Kim YJ, Hur SH, Seong IW, Chae JK, Cho MC, Bae JH, Choi DH, Jang YS, Chae IH, Kim CJ, Yoon JH, Chung WS, Seung KB, Park SJ, KAMIR Investigators. Unrestricted use of 2 new-generation drug-eluting stents in patients with acute myocardial infarction: a propensity score-matched analysis. JACC: Cardiovasc. Interv. 2012; 5: 936-945. 10.1016/j.jcin.2012.05. 009
20. Sridhar R, Venugopal JR, Sundarrajan S, Ravichandran R, Ramalingam B, Ramakrishna S. Electrospun nanofibers for pharmaceutical and medical applications. J. Drug Del. Sci. Tech. 2013; 21: 451-468.
21. 12 loaded polycaprolactone nanofibers: a novel transdermal route for the water soluble energy supplement delivery. Int. J. Pharm. 2013; 444: 70-76. 10.1016/j.ijpharm.2013.01.040
22. Sridhar R, Sundarrajan S, Venugopal JR, Ravichandran R, Ramakrishna S. Electrospun inorganic and polymer composite nanofibers for biomedical applications. J. Biomater. Sci. Polym. Ed. 2013; 24: 365-385. 10.1080/09205063.2012.690711
23. Qingfa G, Xiang L, Ding Q, Li D, Zhao Q, Xie P, Tang X, Luo F, Qian Z. Preparation and characterization of poly(pluronic-co-l-lactide) nanofibers for tissue engineering. Int. J. Biol. Macromol. 2013; 58: 79-86.
24. Peng J, Qian Z, Wang B, Fu S, Guo G, Luo F, Li R, Wu D. Preparation and release characteristic of quercetin loaded poly(lactic acid) ultrafine fibers. J. Nanosci. Nanotechnol. 2011; 11: 3659-3668. 10.1166/jnn.2011.3807
25. Guo G, Fu S, Zhou L, Liang H, Fan M, Luo F, Qian Z, Wei Y. Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε- caprolactone) nanofibers and their in vitro antitumor activity against Glioma 9L cells. Nanoscale. 2011; 3: 3825-3832. 10.1039/c1nr10484e
26. Guo Q, Li X, Yang Y, Wei J, Zhao Q, Luo F, Qian Z. Enhanced 4T1 breast carcinoma anticancer activity by co-delivery of doxorubicin and curcumin with core-shell drug-carrier based on heparin modified poly(L-lactide) grafted polyethylenimine cationic nanoparticles. J. Biomed. Nanotechnol. 2014; 10: 227-237. 10.1166/jbn.2014.1785
27. Rejinold KPNS, Muthunarayanan M, Chennazhi KP, Nair SV, Jayakumar R. Curcumin loaded fibrinogen nanoparticles for cancer drug delivery. J. Biomed. Nanotechnol. 2011; 7: 521-534. 10.1166/jbn.2011.1320
28. Nikkola L, Vapalahti K, Huolman R, Seppälä J, Harlin A, Ashammakhi N. Multilayer implant with triple drug releasing properties. J. Biomed. Nanotechnol. 2008; 4: 331-338. 10.1166/jbn.2008.337
29. Yoo JJ, Kim C, Chung CW, Jeong YI, Kang DH. 5-aminolevulinic acid-incorporated poly(vinyl alcohol) nanofiber-coated metal stent for application in photodynamic therapy. Int. J. Nanomed. 2012; 7: 1997-2005.
30. Heo DN, Lee JB, Bae MS, Hwang YS, Kwon KH, Kwon IK. Development of nanofiber coated indomethacin-eluting stent for tracheal regeneration. J. Nanosci. Nanotechnol. 2011; 11: 5711-5716. 10.1166/jnn.2011.4495
31. Chen DW, Liao JY, Liu SJ, Chan EC. Novel biodegradable sandwich-structured nanofibrous drug-eluting membranes for repair of infected wounds: an in vitro and in vivo study. Int. J. Nanomedicine. 2012; 7: 763-771.
32. Ball C, Krogstad E, Chaowanachan T, Woodrow KA. Drug-eluting fibers for HIV-1 inhibition and contraception. PLoS One. 2012; 7: e49792. 10.1371/journal.pone.0049792
33. Tseng YY, Kao YC, Liao JY, Chen WA, Liu SJ. Biodegradable drug-eluting poly[lactic-co-glycol acid] nanofibers for the sustainable delivery of vancomycin to brain tissue: in vitro and in vivo Studies. ACS Chem. Neurosci. 2013; 4: 1314-1321. 10.1021/cn400108q
34. Tseng YY, Liao JY, Chen WA, Kao YC, Liu SJ. Biodegradable poly([D,L]-lactide-co-glycolide) nanofibers for the sustainable delivery of lidocaine into the epidural space after laminectomy. Nanomedicine. 2014; 9: 77-87. 10.2217/nnm.13.42
35. Zhu YQ, Cui WG, Cheng YS, Chang J, Chen NW, Yan L. Evaluation of biodegradable paclitaxel-eluting nanofibre-covered metal stents for the treatment of benign cardia stricture in an experimental model. Br. J. Surg. 2013; 100: 784-793. 10.1002/bjs.9106
36. Yallapu MM, Jaggi M, Chauhan SC. Curcumin nanoformulations: a future nanomedicine for cancer. Drug Dis. Today. 2012; 17: 71-80. 10.1016/j.drudis. 2011.09.009
37. Grynkiewicz G, Ślifirski P. Curcumin and curcuminoids in quest for medicinal status. Acta Biochim. Pol. 2012; 59: 201-212.
38. Bar-Sela G, Epelbaum R, Schaffer M. Curcumin as an anti-cancer agent: review of the gap between basic and clinical applications. Curr. Med. Chem. 2010; 17: 190-197. 10.2174/092986710790149738
39. Elakkiya T, Malarvizhi G, Sheeja R, Natarajan TS. Curcumin loaded electrospun Bombyx mori silk nanofibers for drug delivery. Polym. Int. 2014; 63: 100-105. 10.1002/pi.2014.63.issue-1
40. Elakkiya T, Sheeja R, Ramadhar K, Natarajan TS. Biocompatibility studies of electrospun nanofibrous membrane of PLLA-PVA blend. J. Appl. Polym. Sci. 2013; 128: 2840-2846. 10.1002/app.v128.5
41. Merrell JG, McLaughlin SW, Tie L, Laurencin CT, Chen AF, Nair LS. Curcumin-loaded poly(ε-caprolactone) nanofibres: diabetic wound dressing with anti-oxidant and anti-inflammatory properties. Clin. Exp. Pharmacol. Physiol. 2009; 36: 1149-1156. 10.1111/cep.2009.36.issue-12
42. Gang G, ShaoZhi F, LiangXue Z, Hang L, Min F, Feng L, ZhiYong Q, YuQuan W. Preparation of curcumin loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) nanofibers and their in vitro antitumor activity against Glioma 9L cells. Nanoscale. 2011; 3: 3825.
43. Ghosh D, Bose A, Haque E, Baral R. Neem (Azadirachta indica) leaf preparation prevents leukocyte apoptosis mediated by cisplatin plus 5-fluorouracil treatment in Swiss mice. Chemotherapy. 2009; 55: 137-144. 10.1159/000211558
44. Mahapatra S, Karnes RJ, Holmes MW, Young CY, Cheville JC, Kohli M, Klee EW, Tindall DJ, Donkena KV. Novel molecular targets of Azadirachta indica associated with inhibition of tumor growth in prostate cancer. AAPS J. 2011; 13: 365-377. 10.1208/s12248-011-9279-4
45. Vasenwala SM, Seth R, Haider N, Islam N, Khan T, Maheshwari V, Ur Rehman S. A study on antioxidant and apoptotic effect of Azadirachta Indica (neem) in cases of cervical cancer. Arch. Gynecol. Obstet. 2012; 286: 1255-1259. 10.1007/s00404-012-2428-x
46. Jin G, Prabhakaran MP, Kai D, Annamalai SK, Arunachalam KD, Ramakrishna S. Tissue engineered plant extracts as nanofibrous wound dressing. Biomaterials. 2013; 34: 724-734.
47. Lu JJ, Bao JL, Wu GS, Xu WS, Huang MQ, Chen XP, Wang YT. Quinones derived from plant secondary metabolites as anti-cancer agents. Anti-cancer Agents Med. Chem. 2013; 13: 456-463. 10.2174/1871520611313030008
48. Ibrahim U, Arda A, Halime S. Preparation of PVA/PAA/PEG/PVP nanofibers with HPMC and aloe vera. Curr. Nanosci. 2013; 9: 489-493.
49. Kolev TM, Velcheva EA, Stamboliyska BA, Spiteller M. DFT and experimental studies of the structure and vibrational spectra of curcumin. Int. J. Quantum Chem. 2005; 102: 1069-1079. 10.1002/(ISSN)1097-461X
50. Bich VT, Thuy NT, Binh NT, Huong NTM, Yen PND, Luong TT. Structural and spectral properties of curcumin and metal-curcumin complex derived from turmeric (Curcuma longa). In: DT Cat, A Pucci, K Wandelt., editor. Physics and engineering of new materials. Berlin: Springer; 2009; 271-278.
51. Chauhan A, Zubair S, Sherwani A, Owais M. Aloe vera induced biomimetic assemblage of nucleobase into nanosized particles. PLoS One. 2012; 7: e32049. 10.1371/journal.pone.0032049
52. Zhang YQ, Xu J, Yin ZQ, Jia RY, Lu Y, Yang F, Du YH, Zou P, Lv C, Hu TX, Liu SL, Shu G, Yi G. Isolation and identification of the antibacterial active compound from petroleum ether extract of neem oil. Fitoterapia. 2010; 81: 747-750. 10.1016/j.fitote.2010.03.015