메뉴 건너뛰기




Volumn 5, Issue 6, 2014, Pages

Validation of a chloroquine-induced cell death mechanism for clinical use against malaria

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; ANTIMALARIAL AGENT; HEMOPROTEIN; HEMOZOIN;

EID: 84903766653     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2014.265     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 79957703902 scopus 로고    scopus 로고
    • A research agenda for malaria eradication: Drugs
    • The malERA Consultative Group on Drugs
    • The malERA Consultative Group on Drugs. A research agenda for malaria eradication: drugs. PLoS Med 2011; 8: e1000402.
    • (2011) PLoS Med , vol.8
  • 2
    • 77954745330 scopus 로고    scopus 로고
    • Spirotetrahydro beta-carbolines (spiroindolones): A new class of potent and orally efficacious compounds for the treatment of malaria
    • Yeung BK, Zou B, Rottmann M, Lakshminarayana SB, Ang SH, Leong SY et al. Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria. J Med Chem 2010; 53: 5155-5164.
    • (2010) J Med Chem , vol.53 , pp. 5155-5164
    • Yeung, B.K.1    Zou, B.2    Rottmann, M.3    Lakshminarayana, S.B.4    Ang, S.H.5    Leong, S.Y.6
  • 4
    • 84877735534 scopus 로고    scopus 로고
    • A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria
    • Ch'ng JH, Mok S, Bozdech Z, Lear MJ, Boudhar A, Russell B et al. A whole cell pathway screen reveals seven novel chemosensitizers to combat chloroquine resistant malaria. Sci Rep 2013; 3: 1734.
    • (2013) Sci Rep , vol.3 , pp. 1734
    • Ch'ng, J.H.1    Mok, S.2    Bozdech, Z.3    Lear, M.J.4    Boudhar, A.5    Russell, B.6
  • 5
    • 79959211816 scopus 로고    scopus 로고
    • A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases
    • Ch'ng JH, Kotturi SR, Chong AG, Lear MJ, Tan KS. A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases. Cell Death Dis 2010; 1: e26.
    • (2010) Cell Death Dis , vol.1
    • Ch'ng, J.H.1    Kotturi, S.R.2    Chong, A.G.3    Lear, M.J.4    Tan, K.S.5
  • 6
    • 80055012546 scopus 로고    scopus 로고
    • Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum
    • Ch'ng JH, Liew K, Goh AS, Sidhartha E, Tan KS. Drug-induced permeabilization of parasite's digestive vacuole is a key trigger of programmed cell death in Plasmodium falciparum. Cell Death Dis 2011; 2: e216.
    • (2011) Cell Death Dis , vol.2
    • Ch'ng, J.H.1    Liew, K.2    Goh, A.S.3    Sidhartha, E.4    Tan, K.S.5
  • 8
    • 0014004971 scopus 로고
    • Chloroquine: Physiological basis of drug resistance in Plasmodium berghei
    • Macomber PB, O'Brien RL, Hahn FE. Chloroquine: physiological basis of drug resistance in Plasmodium berghei. Science 1966; 152: 1374-1375.
    • (1966) Science , vol.152 , pp. 1374-1375
    • Macomber, P.B.1    O'brien, R.L.2    Hahn, F.E.3
  • 9
    • 0023226814 scopus 로고
    • Lysis of malarial parasites and erythrocytes by ferriprotoporphyrin IX-chloroquine and the inhibition of this effect by proteins
    • Zhang Y, Hempelmann E. Lysis of malarial parasites and erythrocytes by ferriprotoporphyrin IX-chloroquine and the inhibition of this effect by proteins. Biochem Pharmacol 1987; 36: 1267-1273.
    • (1987) Biochem Pharmacol , vol.36 , pp. 1267-1273
    • Zhang, Y.1    Hempelmann, E.2
  • 10
    • 0037154180 scopus 로고    scopus 로고
    • Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine
    • Banerjee R, Liu J, Beatty W, Pelosof L, Klemba M, Goldberg DE. Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine. Proc Natl Acad Sci USA 2002; 99: 990-995.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 990-995
    • Banerjee, R.1    Liu, J.2    Beatty, W.3    Pelosof, L.4    Klemba, M.5    Goldberg, D.E.6
  • 11
    • 80053336043 scopus 로고    scopus 로고
    • Falcipains and other cysteine proteases of malaria parasites
    • Rosenthal PJ. Falcipains and other cysteine proteases of malaria parasites. Adv Exp Med Biol 2011; 712: 30-48.
    • (2011) Adv Exp Med Biol , vol.712 , pp. 30-48
    • Rosenthal, P.J.1
  • 13
    • 0031847073 scopus 로고    scopus 로고
    • Quinoline antimalarials: Mechanisms of action and resistance and prospects for new agents
    • Foley M, Tilley L. Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents. Pharmacol Ther 1998; 79: 55-87.
    • (1998) Pharmacol Ther , vol.79 , pp. 55-87
    • Foley, M.1    Tilley, L.2
  • 14
    • 0020953385 scopus 로고
    • Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro
    • Yayon A, Vande Waa JA, Yayon M, Geary TG, Jensen JB. Stage-dependent effects of chloroquine on Plasmodium falciparum in vitro. J Protozool 1983; 30: 642-647.
    • (1983) J Protozool , vol.30 , pp. 642-647
    • Yayon, A.1    Vande Waa, J.A.2    Yayon, M.3    Geary, T.G.4    Jensen, J.B.5
  • 15
    • 0001360814 scopus 로고
    • Spontaneous resistance to chloroquine in a strain of rodent malaria (Plasmodium berghei yoelii)
    • Warhurst DC, Killick-Kendrick R. Spontaneous resistance to chloroquine in a strain of rodent malaria (Plasmodium berghei yoelii). Nature 1967; 213: 1048-1049.
    • (1967) Nature , vol.213 , pp. 1048-1049
    • Warhurst, D.C.1    Killick-Kendrick, R.2
  • 16
    • 0014218449 scopus 로고
    • Mode of action of chloroquine on Plasmodium berghei and P
    • Warhurst DC, Hockley DJ. Mode of action of chloroquine on Plasmodium berghei and P. cynomolgi. Nature 1967; 214: 935-936.
    • (1967) Cynomolgi. Nature , vol.214 , pp. 935-936
    • Warhurst, D.C.1    Hockley, D.J.2
  • 17
    • 0014218407 scopus 로고
    • Morphological effects of chloroquine on Plasmodium berghei in mice
    • Macomber PB, Sprinz H. Morphological effects of chloroquine on Plasmodium berghei in mice. Nature 1967; 214: 937-939.
    • (1967) Nature , vol.214 , pp. 937-939
    • Macomber, P.B.1    Sprinz, H.2
  • 18
    • 0021891710 scopus 로고
    • Chloroquine and desethylchloroquine in plasma, serum, and whole blood: Problems in assay and handling of samples
    • Rombo L, Ericsson O, Alvan G, Lindstrom B, Gustafsson LL, Sjoqvist F. Chloroquine and desethylchloroquine in plasma, serum, and whole blood: problems in assay and handling of samples. Ther Drug Monit 1985; 7: 211-215.
    • (1985) Ther Drug Monit , vol.7 , pp. 211-215
    • Rombo, L.1    Ericsson, O.2    Alvan, G.3    Lindstrom, B.4    Gustafsson, L.L.5    Sjoqvist, F.6
  • 20
    • 0028505208 scopus 로고
    • The pharmacokinetics of chloroquine in healthy and Plasmodium chabaudi-infected mice: Implications for chronotherapy
    • Cambie G, Verdier F, Gaudebout C, Clavier F, Ginsburg H. The pharmacokinetics of chloroquine in healthy and Plasmodium chabaudi-infected mice: implications for chronotherapy. Parasite 1994; 1: 219-226.
    • (1994) Parasite , vol.1 , pp. 219-226
    • Cambie, G.1    Verdier, F.2    Gaudebout, C.3    Clavier, F.4    Ginsburg, H.5
  • 24
    • 79851487308 scopus 로고    scopus 로고
    • Similar efficacy and tolerability of double-dose chloroquine and artemether-lumefantrine for treatment of Plasmodium falciparum infection in Guinea-Bissau: A randomized trial
    • Ursing J, Kofoed PE, Rodrigues A, Blessborn D, Thoft-Nielsen R, Bjorkman A et al. Similar efficacy and tolerability of double-dose chloroquine and artemether-lumefantrine for treatment of Plasmodium falciparum infection in Guinea-Bissau: a randomized trial. J Infect Dis 2011; 203: 109-116.
    • (2011) J Infect Dis , vol.203 , pp. 109-116
    • Ursing, J.1    Kofoed, P.E.2    Rodrigues, A.3    Blessborn, D.4    Thoft-Nielsen, R.5    Bjorkman, A.6
  • 25
    • 0026081226 scopus 로고
    • Efficacy of a loading dose of oral chloroquine in a 36-hour treatment schedule for uncomplicated Plasmodium falciparum malaria
    • Pussard E, Lepers JP, Clavier F, Raharimalala L, Le Bras J, Frisk-Holmberg M et al. Efficacy of a loading dose of oral chloroquine in a 36-hour treatment schedule for uncomplicated Plasmodium falciparum malaria. Antimicrob Agents Chemother 1991; 35: 406-409.
    • (1991) Antimicrob Agents Chemother , vol.35 , pp. 406-409
    • Pussard, E.1    Lepers, J.P.2    Clavier, F.3    Raharimalala, L.4    Le Bras, J.5    Frisk-Holmberg, M.6
  • 27
    • 84859738849 scopus 로고    scopus 로고
    • A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development
    • Malleret B, Claser C, Ong AS, Suwanarusk R, Sriprawat K, Howland SW et al. A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development. Sci Rep 2011; 1: 118.
    • (2011) Sci Rep , vol.1 , pp. 118
    • Malleret, B.1    Claser, C.2    Ong, A.S.3    Suwanarusk, R.4    Sriprawat, K.5    Howland, S.W.6
  • 28
    • 79955101097 scopus 로고    scopus 로고
    • Comparison of the in vitro invasive capabilities of Plasmodium falciparum schizonts isolated by Percoll gradient or using magnetic based separation
    • Spadafora C, Gerena L, Kopydlowski KM. Comparison of the in vitro invasive capabilities of Plasmodium falciparum schizonts isolated by Percoll gradient or using magnetic based separation. Malar J 2011; 10: 55.
    • (2011) Malar J , vol.10 , pp. 55
    • Spadafora, C.1    Gerena, L.2    Kopydlowski, K.M.3
  • 29
    • 79851482799 scopus 로고    scopus 로고
    • Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes
    • Ecker A, Lakshmanan V, Sinnis P, Coppens I, Fidock DA. Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytes. J Infect Dis 2011; 203: 228-236.
    • (2011) J Infect Dis , vol.203 , pp. 228-236
    • Ecker, A.1    Lakshmanan, V.2    Sinnis, P.3    Coppens, I.4    Fidock, D.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.