Aerobic exercise and not a diet supplemented with jussara açaí (Euterpe edulis Martius) alters hepatic oxidative and inflammatory biomarkers in ApoE-deficient mice

British Journal of Nutrition

Volumn 112, Issue 3, 2014, Pages 285-294

  De Castro, Cynthia Aparecida ^a   Natali, Antonio José ^a   Cardoso, Luciana Marques ^a   Ferreira Machado, Alessandra Barbosa ^b   Novello, Alexandre Azevedo ^a   Da Silva, Karina Ana ^a   Tafuri, Natalia Filard ^a   Da Matta, Sergio Luis Pinto ^a   Pedrosa, Maria Lucia ^c   Peluzio, Maria Do Carmo Gouveia ^a  

^a FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^b FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

^c FEDERAL UNIVERSITY OF OURO PRETO   (Brazil)

Author keywords

Anthocyanins; Antioxidants; Atherosclerosis; Physical activity

Indexed keywords

BIOLOGICAL MARKER; LIPID; MONOCYTE CHEMOTACTIC PROTEIN 1; SUPEROXIDE DISMUTASE; ANTHOCYANIN; APOLIPOPROTEIN E; CITRATE SYNTHASE; EUTERPE EDULIS EXTRACT; MESSENGER RNA; PLANT EXTRACT; UNCLASSIFIED DRUG;

AEROBIC EXERCISE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARECACEAE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; EUTERPE EDULIS MARTIUS; FOOD INTAKE; FRUIT; GENE EXPRESSION; HISTOPATHOLOGY; INFLAMMATION; LIPID BLOOD LEVEL; LIVER LEVEL; LIVER WEIGHT; MALE; MOUSE; NONHUMAN; OXIDATION; PHYSICAL ACTIVITY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RUNNING; TISSUE LEVEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; HYPOBETALIPOPROTEINEMIA; LIVER; MEDICINAL PLANT; PULPING;

EUTERPE EDULIS; JUSSARA; MUS;

ANIMALS; ANTHOCYANINS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOLIPOPROTEINS E; ARECACEAE; BIOLOGICAL MARKERS; CHEMOKINE CCL2; CITRATE (SI)-SYNTHASE; DIET; DIETARY SUPPLEMENTS; FRUIT; INFLAMMATION; LIVER; MALE; MICE; MICE, KNOCKOUT; MUSCLES; OXIDATION-REDUCTION; PHYSICAL CONDITIONING, ANIMAL; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 84903758210     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S000711451400083X     Document Type: Article

References (56)

1. De Brito ES, de Araujo MC, Alves RE, et al. (2007) Anthocyanins present in selected tropical fruits: acerola, jambolao, jussara, and guajiru. J Agric Food Chem 55, 9389-9394. (Pubitemid 350205287)
2. Kong JM, Chia LS, Goh NK, et al. (2003) Analysis and biological activities of anthocyanins. Phytochemistry 64, 923-933.
3. Wallace TC (2011) Anthocyanins in cardiovascular disease. Adv Nutr 2, 1-7.
4. Mozaffarian D, Wilson PW & Kannel WB (2008) Beyond established and novel risk factors: lifestyle risk factors for cardiovascular disease. Circulation 117, 3031-3038.
5. World Health Organization (2011) Global Atlas on Cardiovascular Disease Prevention and Control. Geneva: WHO.
6. Hansson G (2005) Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352, 1685-1695.
7. Targher G, Bertolini L, Padovani R, et al. (2006) Nonalcoholic fatty liver disease is associated with carotid artery wall thickness in diet-controlled type 2 diabetic patients. J Endocrinol Invest 29, 55-60. (Pubitemid 43355836)
8. Albano E (2006) Alcohol, oxidative stress and free radical damage. Proc Nutr Soc 65, 278-290. (Pubitemid 46323842)
9. Baggiolini M (1998) Chemokines and leukocyte traffic. Nature 392, 565-568. (Pubitemid 28207705)
10. Kanda H, Tateya S, Tamori Y, et al. (2006) MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 116, 1494-1505.
11. Smith SC, Allen J, Blair SN, et al. (2006) AHA/ACC guidelines for secondary prevention for patients with coronary and other atherosclerotic vascular disease: 2006 update: endorsed by the National Heart, Lung, and Blood Institute. Circulation 113, 2363-2372. (Pubitemid 43947981)
12. Jensen GS, Wu X, Patterson KM, et al. (2008) In vitro and in vivo antioxidant and anti-inflammatory capacities of an antioxidant-rich fruit and berry juice blend. Results of a pilot and randomized, double-blinded, placebo-controlled, crossover study. J Agric Food Chem 56, 8326-8333.
13. Xie C, Kang J, Burris R, et al. (2011) Aça?́ juice attenuates atherosclerosis in ApoE deficient mice through antioxidant and anti-inflammatory activities. Atherosclerosis 216, 327-333.
14. Souza MO, Silva M, Silva ME, et al. (2010) Diet supplementation with aça?́ (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats. Nutrition 26, 804-810.
15. Radak Z, Chung HY, Naito H, et al. (2004) Age-associated increases in oxidative stress and nuclear transcription factor kB activation are attenuated in rat liver by regular exercise. FASEB J 18, 749-750.
16. Brooks SV, Vasilaki A, Larkin LM, et al. (2008) Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kB activation. J Physiol 596, 3979-3990.
17. Radak Z, Chung HY & Goto S (2008) Systemic adaptation to oxidative challenge induced by regular exercise. Free Rad Biol Med 44, 153-159.
18. Da Silva LA, Pinho CA, Rocha LGC, et al. (2009) Effect of different models of physical exercise on oxidative stress markers in mouse liver. Appl Physiol Nut Met 34, 60-65.
19. Teodoro BG, Natali AJ, Fernandes SAT, et al. (2012) Improvements of atherosclerosis and hepatic oxidative stress are independent of exercise intensity in LDLr2/2 mice. J Atheroscler Thromb 19, 904-911.
20. Association of Official Analytical Chemists (1989) Guidelines for collaborative study procedure to validate characteristics of a method of analysis. J Assoc Off Anal Chem 72, 694-704.
21. Giusti MM & Wrosltad RE (2001) Anthocyanins. Characterization and measurement of anthocyanins by UV-visible spectroscopy. In Current Protocols in Food Analytical Chemistry Hand Book of Food Analytical Chemistry, pp. 1-13 [RE Wrolstad, editor]. New York, NY: John Wiley & Sons.
22. Schauss AG, Wu X, Prior RL, et al. (2006) Phytochemical and nutrient composition of the freeze-dried Amazonian palm berry, Euterpe oleracea Mart. (aça?́). J Agric Food Chem 54, 8598-8603. (Pubitemid 44747671)
23. Reeves PG, Nielsen FH & Fahey GC (1993) AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939-1951. (Pubitemid 23342492)
24. World Health Organization (2003) Fruit and vegetable promotion initiative report of the meeting, Geneva, 25-27 August 2003. Geneva: WHO
25. Souza MO, Silva LS, Magalha?es CLB, et al. (2012) The hypocholesterolemic activity of aça?́ (Euterpe oleracea Mart.) is mediated by the enhanced expression of the ATP-binding cassette, subfamily G transporters 5 and 8 and low-density lipoprotein receptor genes in the rat. Nutr Res 32, 976-984.
26. Høydal MA, Wisløff U, Kemi OJ, et al. (2007) Running speed and maximal oxygen uptake in rats and mice: practical implications for exercise training. Eur J Cardiovas Prev Rehab 14, 753-760. (Pubitemid 350197002)
27. Alp PR, Newsholme EA & Zammit VA (1976) Activities of citrate synthase and NAD-linked and NADP-linked isocitrate dehydrogenase in muscle from vertebrates and invertebrates. Biochem J 154, 689-700.
28. Dieterich S, Bieligk U, Beulich K, et al. (2000) Gene expression of antioxidative enzymes in the human heart: increased expression of catalase in the end-stage failing heart. Circulation 101, 33-39. (Pubitemid 30039073)
29. Lowry OH, Rosebrough NJ, Farr AL, et al. (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193, 265-275.
30. Aebi H (1984) Catalase in vitro. Methods Enzimol 105, 121-127.
31. Pfall MW (2001) A new mathematical model for relative quantification in real-time PCR. Nucleic Acids Res 29, 45-53.
32. Livak KJ & Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 (2DDCT) method. Methods 25, 402-408. (Pubitemid 34164012)
33. Palinski W, Ord VA, Plump AS, et al. (1994) ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb 14, 605-616.
34. Alessio HM & Goldfarb AH (1988) Lipid peroxidation and scavenger enzymes during exercise: adaptative response to training. J Appl Physiol 64, 1333-1336.
35. Spada PDS, Dani C, Bortolini GV, et al. (2009) Frozen fruit pulp of Euterpe oleracea Mart. (aça?́) prevents hydrogen peroxide-induced damage in the cerebral cortex, cerebellum, and hippocampus of rats. J Med Food 12, 1084-1088.
36. Dragsted LO, Pedersen A, Hermetter A, et al. (2004) The 6-a-day study: effects of fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers. Am J Clin Nutr 79, 1060-1072. (Pubitemid 41095959)
37. Trøseid M, Lappegard KT, Claudi T, et al. (2004) Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J 25, 349-355. (Pubitemid 38295445)
38. Garelnabi M, Veledar E, White-Welkley J, et al. (2012) Vitamin E differentially affects short term exercise induced changes in oxidative stress, lipids, and inflammatory markers. Nutr Metab Cardiovasc 22, 907-913.
39. Vieira VJ, Valentine RJ, Wilund KR, et al. (2009) Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. Am J Physiol Endocrinol Metab 296, E1164-E1171.
40. Maiorana A, O'Driscoll G, Cheetham C, et al. (2001) The effect of combined aerobic and resistance exercise training on vascular function in type 2 diabetes. J Am Coll Cardiol 38, 860-866. (Pubitemid 32835765)
41. Daugherty A (2002) Mouse models of atherosclerosis. Am J Med Sci 323, 3-10. (Pubitemid 34650115)
42. Garcia-Alonso M, Minihane AM, Rimbach G, et al. (2009) Red wine anthocyanins are rapidly absorbed in humans and affect monocyte chemoattractant protein 1 levels and antioxidant capacity of plasma. J Nutr Biochem 20, 521-529.
43. Rector RS, Thyfault JP, Morris RT, et al. (2008) Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. Am J Physiol Gastrointest Liver Physiol 294, G619-G626. (Pubitemid 351468778)
44. Helge JW (2002) Long-term fat diet adaptation effects on performance, training capacity, and fat utilization. Med Sci Sports Exerc 34, 1499-1504. (Pubitemid 35006824)
45. Rull A, Rodriguez F, Aragones G, et al. (2009) Hepatic monocyte chemoattractant protein-1 is upregulated by dietary cholesterol and contributes to liver steatosis. Cytokine 48, 273-279.
46. Gao B (2005) Cytokines, STATs and liver disease. Cell Mol Immunol 2, 92-100.
47. Qin X, Xie X, Fan Y, et al. (2008) Peroxisome proliferatoractivated receptor-delta induces insulin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. Hepatology 48, 432-441.
48. Mulvihill E, Assini JM, Sutherland BG, et al. (2010) Naringenin decreases progression of atherosclerosis by improving dyslipidemia in high-fat-fed low-density lipoprotein receptor- null mice. Arterioscler Thromb Vasc Biol 30, 742-748.
49. Decorde K, Ventura E, Lacan D, et al. (2010) An SOD rich melon extract Extramel prevents aortic lipids and liver steatosis in diet-induced model of atherosclerosis. Nutr Metab Cardiovasc Dis 20, 301-307.
50. Miyazaki K, Makino K, Iwadate E, et al. (2008) Anthocyanins from purple sweet potato Ipomoea batatas cultivar Ayamurasaki suppress the development of atherosclerotic lesions and both enhancements of oxidative stress and soluble vascular cell adhesion molecule-1 in apolipoprotein E-deficient mice. J Agric Food Chem 56, 11485-11492.
51. Piedrahita JA, Zhang SH, Hagaman JR, et al. (1992) Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci U S A 89, 4471-4475.
52. Shimada K, Mikami Y, Murayama T, et al. (2011) Atherosclerotic plaques induced by marble-burying behavior are stabilized by exercise training in experimental atherosclerosis. Int J Cardiol 151, 284-289.
53. Meilhac O, Ramachandran S, Chiang K, et al. (2001) Role of arterial wall antioxidant defense in beneficial effects of exercise on atherosclerosis in mice. Arterioscler Thromb Vasc Biol 21, 1681-1688. (Pubitemid 34215591)
54. Fukai T, Siegfried MR, Ushio-Fukai M, et al. (2000) Regulation of the vascular extracellular superoxide dismutase by nitric oxide and exercise training. J Clin Invest 105, 1631-1639.
55. Braz DJ Jr, Gutierrez PS & Da Luz PL (2007) Coronary fat content evaluated by morphometry in patients with severe atherosclerosis has no relation with serum lipid levels. Braz J Med Biol Res 40, 467-473. (Pubitemid 46605019)
56. Xia M, Ling W, Zhu H, et al. (2009) Anthocyanin attenuates CD40-mediated endothelial cell activation and apoptosis by inhibiting CD40-induced MAPK activation. Atherosclerosis 202, 41-47.