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Volumn 28, Issue 3, 2014, Pages 145-154

Allograft rejection and tubulointerstitial fibrosis in human kidney allografts: Interrogation by urinary cell mRNA profiling

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; MESSENGER RNA;

EID: 84903697203     PISSN: 0955470X     EISSN: 15579816     Source Type: Journal    
DOI: 10.1016/j.trre.2014.05.003     Document Type: Review
Times cited : (8)

References (97)
  • 1
    • 33750694341 scopus 로고    scopus 로고
    • National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, U.S.Renal Data System
    • U.S.Renal Data System USRDS 2013 Annual Data Report: Atlas of End-Stage Renal Disease in the United States 2013, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
    • (2013) USRDS 2013 Annual Data Report: Atlas of End-Stage Renal Disease in the United States
  • 2
    • 84883427310 scopus 로고    scopus 로고
    • The gap between estimated incidence of end-stage renal disease and use of therapy
    • Anand S., Bitton A., Gaziano T. The gap between estimated incidence of end-stage renal disease and use of therapy. PLoS One 2013, 8:e72860.
    • (2013) PLoS One , vol.8
    • Anand, S.1    Bitton, A.2    Gaziano, T.3
  • 3
    • 84903688521 scopus 로고    scopus 로고
    • Kidney disease statistics for the United States, National Kidney and Urologic Diseases Information Clearinghouse, National Institutes of Health
    • Kidney disease statistics for the United States, National Kidney and Urologic Diseases Information Clearinghouse, National Institutes of Health, 2012.
    • (2012)
  • 4
    • 80053333600 scopus 로고    scopus 로고
    • Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes
    • Tonelli M., Wiebe N., Knoll G., et al. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant 2011, 11:2093-2109.
    • (2011) Am J Transplant , vol.11 , pp. 2093-2109
    • Tonelli, M.1    Wiebe, N.2    Knoll, G.3
  • 5
    • 0033518231 scopus 로고    scopus 로고
    • Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant
    • Wolfe R.A., Ashby V.B., Milford E.L., et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999, 341:1725-1730.
    • (1999) N Engl J Med , vol.341 , pp. 1725-1730
    • Wolfe, R.A.1    Ashby, V.B.2    Milford, E.L.3
  • 6
    • 84877252421 scopus 로고    scopus 로고
    • OPTN/SRTR 2011 Annual Data Report: kidney
    • Matas A.J., Smith J.M., Skeans M.A., et al. OPTN/SRTR 2011 Annual Data Report: kidney. Am J Transplant 2013, 13:11-46.
    • (2013) Am J Transplant , vol.13 , pp. 11-46
    • Matas, A.J.1    Smith, J.M.2    Skeans, M.A.3
  • 7
    • 40449114529 scopus 로고    scopus 로고
    • Solving the organ shortage crisis: the 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium
    • Pomfret E.A., Sung R.S., Allan J., Kinkhabwala M., Melancon J.K., Roberts J.P. Solving the organ shortage crisis: the 7th Annual American Society of Transplant Surgeons' State-of-the-Art Winter Symposium. Am J Transplant 2008, 8:745-752.
    • (2008) Am J Transplant , vol.8 , pp. 745-752
    • Pomfret, E.A.1    Sung, R.S.2    Allan, J.3    Kinkhabwala, M.4    Melancon, J.K.5    Roberts, J.P.6
  • 9
    • 0034667904 scopus 로고    scopus 로고
    • Increased impact of acute rejection on chronic allograft failure in recent era
    • Meier-Kriesche H.U., Ojo A.O., Hanson J.A., et al. Increased impact of acute rejection on chronic allograft failure in recent era. Transplantation 2000, 70:1098-1100.
    • (2000) Transplantation , vol.70 , pp. 1098-1100
    • Meier-Kriesche, H.U.1    Ojo, A.O.2    Hanson, J.A.3
  • 10
    • 44649146622 scopus 로고    scopus 로고
    • Impact of acute rejection and new-onset diabetes on long-term transplant graft and patient survival
    • Cole E.H., Johnston O., Rose C.L., Gill J.S. Impact of acute rejection and new-onset diabetes on long-term transplant graft and patient survival. Clin J Am Soc Nephrol 2008, 3:814-821.
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 814-821
    • Cole, E.H.1    Johnston, O.2    Rose, C.L.3    Gill, J.S.4
  • 11
    • 84891633515 scopus 로고    scopus 로고
    • Predictors of graft failure and death in elderly kidney transplant recipients
    • Faravardeh A., Eickhoff M., Jackson S., et al. Predictors of graft failure and death in elderly kidney transplant recipients. Transplantation 2013, 96:1089-1096.
    • (2013) Transplantation , vol.96 , pp. 1089-1096
    • Faravardeh, A.1    Eickhoff, M.2    Jackson, S.3
  • 12
    • 84897109225 scopus 로고    scopus 로고
    • Predicting 5-year risk of kidney transplant failure: a prediction instrument using data available at 1 year posttransplantation
    • Shabir S., Halimi J.M., Cherukuri A., et al. Predicting 5-year risk of kidney transplant failure: a prediction instrument using data available at 1 year posttransplantation. Am J Kidney Dis 2014, 63:643-651.
    • (2014) Am J Kidney Dis , vol.63 , pp. 643-651
    • Shabir, S.1    Halimi, J.M.2    Cherukuri, A.3
  • 13
    • 0030984291 scopus 로고    scopus 로고
    • Acute rejection of renal allografts: mechanistic insights and therapeutic options
    • Suthanthiran M. Acute rejection of renal allografts: mechanistic insights and therapeutic options. Kidney Int 1997, 51:1289-1304.
    • (1997) Kidney Int , vol.51 , pp. 1289-1304
    • Suthanthiran, M.1
  • 15
    • 77957734604 scopus 로고    scopus 로고
    • Rejection of the kidney allograft
    • Nankivell B.J., Alexander S.I. Rejection of the kidney allograft. N Engl J Med 2010, 363:1451-1462.
    • (2010) N Engl J Med , vol.363 , pp. 1451-1462
    • Nankivell, B.J.1    Alexander, S.I.2
  • 17
    • 84879776271 scopus 로고    scopus 로고
    • Urinary-cell mRNA profile and acute cellular rejection in kidney allografts
    • Suthanthiran M., Schwartz J.E., Ding R., et al. Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med 2013, 369:20-31.
    • (2013) N Engl J Med , vol.369 , pp. 20-31
    • Suthanthiran, M.1    Schwartz, J.E.2    Ding, R.3
  • 18
    • 84884907939 scopus 로고    scopus 로고
    • Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury
    • Hricik D.E., Nickerson P., Formica R.N., et al. Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury. Am J Transplant 2013, 13:2634-2644.
    • (2013) Am J Transplant , vol.13 , pp. 2634-2644
    • Hricik, D.E.1    Nickerson, P.2    Formica, R.N.3
  • 19
    • 84883456555 scopus 로고    scopus 로고
    • Kidney allograft survival after acute rejection, the value of follow-up biopsies
    • El Ters M., Grande J.P., Keddis M.T., et al. Kidney allograft survival after acute rejection, the value of follow-up biopsies. Am J Transplant 2013, 13:2334-2341.
    • (2013) Am J Transplant , vol.13 , pp. 2334-2341
    • El Ters, M.1    Grande, J.P.2    Keddis, M.T.3
  • 20
    • 0016683869 scopus 로고
    • Identity and cytotoxic capacity of cells infiltrating renal allografts
    • Strom T.B., Tilney N.L., Carpenter C.B., Busch G.J. Identity and cytotoxic capacity of cells infiltrating renal allografts. N Engl J Med 1975, 292:1257-1263.
    • (1975) N Engl J Med , vol.292 , pp. 1257-1263
    • Strom, T.B.1    Tilney, N.L.2    Carpenter, C.B.3    Busch, G.J.4
  • 21
    • 0016616138 scopus 로고
    • Detection of canine kidney allograft rejection with 51Cr-labeled lymphocytes
    • Williams L.E., Merino G.E., Goren G., Najarian J.S., Loken M.K. Detection of canine kidney allograft rejection with 51Cr-labeled lymphocytes. Radiology 1975, 115:205-206.
    • (1975) Radiology , vol.115 , pp. 205-206
    • Williams, L.E.1    Merino, G.E.2    Goren, G.3    Najarian, J.S.4    Loken, M.K.5
  • 23
    • 0036217977 scopus 로고    scopus 로고
    • Lymphocyte-mediated cytotoxicity
    • Russell J.H., Ley T.J. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 2002, 20:323-370.
    • (2002) Annu Rev Immunol , vol.20 , pp. 323-370
    • Russell, J.H.1    Ley, T.J.2
  • 24
    • 8044220289 scopus 로고    scopus 로고
    • Molecular executors of cell death-differential intrarenal expression of Fas ligand, Fas, granzyme B, and perforin during acute and/or chronic rejection of human renal allografts
    • Sharma V.K., Bologa R.M., Li B., et al. Molecular executors of cell death-differential intrarenal expression of Fas ligand, Fas, granzyme B, and perforin during acute and/or chronic rejection of human renal allografts. Transplantation 1996, 62:1860-1866.
    • (1996) Transplantation , vol.62 , pp. 1860-1866
    • Sharma, V.K.1    Bologa, R.M.2    Li, B.3
  • 25
    • 0028213824 scopus 로고
    • Heightened intragraft CTL gene expression in acutely rejecting renal allografts
    • Lipman M.L., Stevens A.C., Strom T.B. Heightened intragraft CTL gene expression in acutely rejecting renal allografts. J Immunol 1994, 152:5120-5127.
    • (1994) J Immunol , vol.152 , pp. 5120-5127
    • Lipman, M.L.1    Stevens, A.C.2    Strom, T.B.3
  • 26
    • 0031000670 scopus 로고    scopus 로고
    • Molecular analyses of human renal allografts: differential intragraft gene expression during rejection
    • Suthanthiran M. Molecular analyses of human renal allografts: differential intragraft gene expression during rejection. Kidney Int Suppl 1997, 58:S15-S21.
    • (1997) Kidney Int Suppl , vol.58
    • Suthanthiran, M.1
  • 27
    • 0029948767 scopus 로고    scopus 로고
    • The intragraft gene activation of markers reflecting T-cell-activation and -cytotoxicity analyzed by quantitative RT-PCR in renal transplantation
    • Strehlau J., Pavlakis M., Lipman M., Maslinski W., Shapiro M., Strom T.B. The intragraft gene activation of markers reflecting T-cell-activation and -cytotoxicity analyzed by quantitative RT-PCR in renal transplantation. Clin Nephrol 1996, 46:30-33.
    • (1996) Clin Nephrol , vol.46 , pp. 30-33
    • Strehlau, J.1    Pavlakis, M.2    Lipman, M.3    Maslinski, W.4    Shapiro, M.5    Strom, T.B.6
  • 29
    • 0020056186 scopus 로고
    • Hyperacute rejection of HLA-AB-identical renal allografts associated with B lymphocyte and endothelial reactive antibodies
    • Ahern A.T., Artruc S.B., DellaPelle P., et al. Hyperacute rejection of HLA-AB-identical renal allografts associated with B lymphocyte and endothelial reactive antibodies. Transplantation 1982, 33:103-106.
    • (1982) Transplantation , vol.33 , pp. 103-106
    • Ahern, A.T.1    Artruc, S.B.2    DellaPelle, P.3
  • 30
    • 3042743987 scopus 로고    scopus 로고
    • National conference to assess antibody-mediated rejection in solid organ transplantation
    • Takemoto S.K., Zeevi A., Feng S., et al. National conference to assess antibody-mediated rejection in solid organ transplantation. Am J Transplant 2004, 4:1033-1041.
    • (2004) Am J Transplant , vol.4 , pp. 1033-1041
    • Takemoto, S.K.1    Zeevi, A.2    Feng, S.3
  • 31
    • 0037446624 scopus 로고    scopus 로고
    • Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome
    • Worthington J.E., Martin S., Al-Husseini D.M., Dyer P.A., Johnson R.W. Posttransplantation production of donor HLA-specific antibodies as a predictor of renal transplant outcome. Transplantation 2003, 75:1034-1040.
    • (2003) Transplantation , vol.75 , pp. 1034-1040
    • Worthington, J.E.1    Martin, S.2    Al-Husseini, D.M.3    Dyer, P.A.4    Johnson, R.W.5
  • 32
    • 32844463757 scopus 로고    scopus 로고
    • Frequency and clinical implications of development of donor-specific and non-donor-specific HLA antibodies after kidney transplantation
    • Hourmant M., Cesbron-Gautier A., Terasaki P.I., et al. Frequency and clinical implications of development of donor-specific and non-donor-specific HLA antibodies after kidney transplantation. J Am Soc Nephrol 2005, 16:2804-2812.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2804-2812
    • Hourmant, M.1    Cesbron-Gautier, A.2    Terasaki, P.I.3
  • 33
    • 28544440639 scopus 로고    scopus 로고
    • Predictive value of HLA antibodies and serum creatinine in chronic rejection: results of a 2-year prospective trial
    • Terasaki P.I., Ozawa M. Predictive value of HLA antibodies and serum creatinine in chronic rejection: results of a 2-year prospective trial. Transplantation 2005, 80:1194-1197.
    • (2005) Transplantation , vol.80 , pp. 1194-1197
    • Terasaki, P.I.1    Ozawa, M.2
  • 35
    • 84866739055 scopus 로고    scopus 로고
    • Concurrent acute cellular rejection is an independent risk factor for renal allograft failure in patients with C4d-positive antibody-mediated rejection
    • Matignon M., Muthukumar T., Seshan S.V., Suthanthiran M., Hartono C. Concurrent acute cellular rejection is an independent risk factor for renal allograft failure in patients with C4d-positive antibody-mediated rejection. Transplantation 2012, 94:603-611.
    • (2012) Transplantation , vol.94 , pp. 603-611
    • Matignon, M.1    Muthukumar, T.2    Seshan, S.V.3    Suthanthiran, M.4    Hartono, C.5
  • 36
    • 81255171415 scopus 로고    scopus 로고
    • Our evolving understanding of late kidney allograft failure
    • Gaston R.S. Our evolving understanding of late kidney allograft failure. Curr Opin Organ Transplant 2011, 16:594-599.
    • (2011) Curr Opin Organ Transplant , vol.16 , pp. 594-599
    • Gaston, R.S.1
  • 37
    • 84896873720 scopus 로고    scopus 로고
    • Late kidney dysfunction in a kidney transplant recipient
    • Josephson M.A. Late kidney dysfunction in a kidney transplant recipient. Clin J Am Soc Nephrol 2014, 9:590-597.
    • (2014) Clin J Am Soc Nephrol , vol.9 , pp. 590-597
    • Josephson, M.A.1
  • 38
    • 84859649198 scopus 로고    scopus 로고
    • Renal interstitial fibrosis: mechanisms and evaluation
    • Farris A.B., Colvin R.B. Renal interstitial fibrosis: mechanisms and evaluation. Curr Opin Nephrol Hypertens 2012, 21:289-300.
    • (2012) Curr Opin Nephrol Hypertens , vol.21 , pp. 289-300
    • Farris, A.B.1    Colvin, R.B.2
  • 39
    • 42049107147 scopus 로고    scopus 로고
    • Chronic allograft nephropathy: what have we learned from protocol biopsies?
    • Bosmans J.L., Ysebaert D.K., Verpooten G.A. Chronic allograft nephropathy: what have we learned from protocol biopsies?. Transplantation 2008, 85:S38-S41.
    • (2008) Transplantation , vol.85
    • Bosmans, J.L.1    Ysebaert, D.K.2    Verpooten, G.A.3
  • 40
    • 84893312585 scopus 로고    scopus 로고
    • Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target?
    • Amer H., Griffin M.D. Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target?. Kidney Int 2014, 85:240-243.
    • (2014) Kidney Int , vol.85 , pp. 240-243
    • Amer, H.1    Griffin, M.D.2
  • 41
    • 41749096622 scopus 로고    scopus 로고
    • Late kidney allograft loss: what we know about it, and what we can do about it
    • Jevnikar A.M., Mannon R.B. Late kidney allograft loss: what we know about it, and what we can do about it. Clin J Am Soc Nephrol 2008, 3:S56-S67.
    • (2008) Clin J Am Soc Nephrol , vol.3
    • Jevnikar, A.M.1    Mannon, R.B.2
  • 42
    • 70349309684 scopus 로고    scopus 로고
    • The pathogenesis and treatment of chronic allograft nephropathy
    • Li C., Yang C.W. The pathogenesis and treatment of chronic allograft nephropathy. Nat Rev Nephrol 2009, 5:513-519.
    • (2009) Nat Rev Nephrol , vol.5 , pp. 513-519
    • Li, C.1    Yang, C.W.2
  • 44
    • 80053339743 scopus 로고    scopus 로고
    • The dual role of epithelial-to-mesenchymal transition in chronic allograft injury in pediatric renal transplantation
    • Vitalone M.J., Naesens M., Sigdel T., Li L., Hseih S., Sarwal M.M. The dual role of epithelial-to-mesenchymal transition in chronic allograft injury in pediatric renal transplantation. Transplantation 2011, 92:787-795.
    • (2011) Transplantation , vol.92 , pp. 787-795
    • Vitalone, M.J.1    Naesens, M.2    Sigdel, T.3    Li, L.4    Hseih, S.5    Sarwal, M.M.6
  • 45
    • 78149307632 scopus 로고    scopus 로고
    • Fibrosis with inflammation at one year predicts transplant functional decline
    • Park W.D., Griffin M.D., Cornell L.D., Cosio F.G., Stegall M.D. Fibrosis with inflammation at one year predicts transplant functional decline. J Am Soc Nephrol 2010, 21:1987-1997.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 1987-1997
    • Park, W.D.1    Griffin, M.D.2    Cornell, L.D.3    Cosio, F.G.4    Stegall, M.D.5
  • 46
    • 77956160622 scopus 로고    scopus 로고
    • Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failure
    • Mannon R.B., Matas A.J., Grande J., et al. Inflammation in areas of tubular atrophy in kidney allograft biopsies: a potent predictor of allograft failure. Am J Transplant 2010, 10:2066-2073.
    • (2010) Am J Transplant , vol.10 , pp. 2066-2073
    • Mannon, R.B.1    Matas, A.J.2    Grande, J.3
  • 47
    • 76949097789 scopus 로고    scopus 로고
    • Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients
    • Heilman R.L., Devarapalli Y., Chakkera H.A., et al. Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients. Am J Transplant 2010, 10:563-570.
    • (2010) Am J Transplant , vol.10 , pp. 563-570
    • Heilman, R.L.1    Devarapalli, Y.2    Chakkera, H.A.3
  • 48
    • 43749083711 scopus 로고    scopus 로고
    • Clinical factors associated with graft fibrosis in kidney-transplant recipients on steroid-avoidance immunosuppression
    • Heilman R.L., Chakkera H.A., Reddy K.S., et al. Clinical factors associated with graft fibrosis in kidney-transplant recipients on steroid-avoidance immunosuppression. Clin Transplant 2008, 22:309-315.
    • (2008) Clin Transplant , vol.22 , pp. 309-315
    • Heilman, R.L.1    Chakkera, H.A.2    Reddy, K.S.3
  • 49
    • 84862231537 scopus 로고    scopus 로고
    • Immunosuppressive regimen and interstitial fibrosis and tubules atrophy at 12months postrenal transplant
    • Gelens M.A., Steegh F.M., van Hooff J.P., et al. Immunosuppressive regimen and interstitial fibrosis and tubules atrophy at 12months postrenal transplant. Clin J Am Soc Nephrol 2012, 7:1010-1017.
    • (2012) Clin J Am Soc Nephrol , vol.7 , pp. 1010-1017
    • Gelens, M.A.1    Steegh, F.M.2    van Hooff, J.P.3
  • 50
    • 0028817544 scopus 로고
    • Stimulation of transforming growth factor-beta 1 transcription by cyclosporine
    • Prashar Y., Khanna A., Sehajpal P., Sharma V.K., Suthanthiran M. Stimulation of transforming growth factor-beta 1 transcription by cyclosporine. FEBS Lett 1995, 358:109-112.
    • (1995) FEBS Lett , vol.358 , pp. 109-112
    • Prashar, Y.1    Khanna, A.2    Sehajpal, P.3    Sharma, V.K.4    Suthanthiran, M.5
  • 51
    • 0028787493 scopus 로고
    • Regulation of transforming growth factor-beta 1 and its receptor by cyclosporine in human T lymphocytes
    • Ahuja S.S., Shrivastav S., Danielpour D., Balow J.E., Boumpas D.T. Regulation of transforming growth factor-beta 1 and its receptor by cyclosporine in human T lymphocytes. Transplantation 1995, 60:718-723.
    • (1995) Transplantation , vol.60 , pp. 718-723
    • Ahuja, S.S.1    Shrivastav, S.2    Danielpour, D.3    Balow, J.E.4    Boumpas, D.T.5
  • 52
    • 0030903515 scopus 로고    scopus 로고
    • In vivo hyperexpression of transforming growth factor-beta1 in mice: stimulation by cyclosporine
    • Khanna A., Kapur S., Sharma V., Li B., Suthanthiran M. In vivo hyperexpression of transforming growth factor-beta1 in mice: stimulation by cyclosporine. Transplantation 1997, 63:1037-1039.
    • (1997) Transplantation , vol.63 , pp. 1037-1039
    • Khanna, A.1    Kapur, S.2    Sharma, V.3    Li, B.4    Suthanthiran, M.5
  • 53
    • 0032519407 scopus 로고    scopus 로고
    • In vivo expression of transforming growth factor-beta1 in humans: stimulation by cyclosporine
    • Shin G.T., Khanna A., Ding R., et al. In vivo expression of transforming growth factor-beta1 in humans: stimulation by cyclosporine. Transplantation 1998, 65:313-318.
    • (1998) Transplantation , vol.65 , pp. 313-318
    • Shin, G.T.1    Khanna, A.2    Ding, R.3
  • 54
    • 0033608385 scopus 로고    scopus 로고
    • Tacrolimus induces increased expression of transforming growth factor-beta1 in mammalian lymphoid as well as nonlymphoid cells
    • Khanna A., Cairns V., Hosenpud J.D. Tacrolimus induces increased expression of transforming growth factor-beta1 in mammalian lymphoid as well as nonlymphoid cells. Transplantation 1999, 67:614-619.
    • (1999) Transplantation , vol.67 , pp. 614-619
    • Khanna, A.1    Cairns, V.2    Hosenpud, J.D.3
  • 55
    • 27144507950 scopus 로고    scopus 로고
    • Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells
    • McMorrow T., Gaffney M.M., Slattery C., Campbell E., Ryan M.P. Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells. Nephrol Dial Transplant 2005, 20:2215-2225.
    • (2005) Nephrol Dial Transplant , vol.20 , pp. 2215-2225
    • McMorrow, T.1    Gaffney, M.M.2    Slattery, C.3    Campbell, E.4    Ryan, M.P.5
  • 56
    • 48949116154 scopus 로고    scopus 로고
    • Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells
    • Slattery C., Ryan M.P., McMorrow T. Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells. Int J Biochem Cell Biol 2008, 40:2218-2229.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 2218-2229
    • Slattery, C.1    Ryan, M.P.2    McMorrow, T.3
  • 57
    • 0029937385 scopus 로고    scopus 로고
    • Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy
    • Sharma V.K., Bologa R.M., Xu G.P., et al. Intragraft TGF-beta 1 mRNA: a correlate of interstitial fibrosis and chronic allograft nephropathy. Kidney Int 1996, 49:1297-1303.
    • (1996) Kidney Int , vol.49 , pp. 1297-1303
    • Sharma, V.K.1    Bologa, R.M.2    Xu, G.P.3
  • 58
    • 33646672416 scopus 로고    scopus 로고
    • TGF-beta1 mRNA upregulation influences chronic renal allograft dysfunction
    • Pribylova-Hribova P., Kotsch K., Lodererova A., et al. TGF-beta1 mRNA upregulation influences chronic renal allograft dysfunction. Kidney Int 2006, 69:1872-1879.
    • (2006) Kidney Int , vol.69 , pp. 1872-1879
    • Pribylova-Hribova, P.1    Kotsch, K.2    Lodererova, A.3
  • 59
    • 84889673740 scopus 로고    scopus 로고
    • Expression of fibrosis-related genes in human renal allografts with interstitial fibrosis and tubular atrophy
    • Nogare A.L., Dalpiaz T., Pedroso J.A., et al. Expression of fibrosis-related genes in human renal allografts with interstitial fibrosis and tubular atrophy. J Nephrol 2013, 26:1179-1187.
    • (2013) J Nephrol , vol.26 , pp. 1179-1187
    • Nogare, A.L.1    Dalpiaz, T.2    Pedroso, J.A.3
  • 61
    • 77957273572 scopus 로고    scopus 로고
    • Intragraft tubular vimentin and CD44 expression correlate with long-term renal allograft function and interstitial fibrosis and tubular atrophy
    • Kers J., Xu-Dubois Y.C., Rondeau E., et al. Intragraft tubular vimentin and CD44 expression correlate with long-term renal allograft function and interstitial fibrosis and tubular atrophy. Transplantation 2010, 90:502-509.
    • (2010) Transplantation , vol.90 , pp. 502-509
    • Kers, J.1    Xu-Dubois, Y.C.2    Rondeau, E.3
  • 62
    • 49649101155 scopus 로고    scopus 로고
    • Early epithelial phenotypic changes predict graft fibrosis
    • Hertig A., Anglicheau D., Verine J., et al. Early epithelial phenotypic changes predict graft fibrosis. J Am Soc Nephrol 2008, 19:1584-1591.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1584-1591
    • Hertig, A.1    Anglicheau, D.2    Verine, J.3
  • 63
    • 84880141342 scopus 로고    scopus 로고
    • Reduction of chronic rejection of renal allografts by anti-transforming growth factor-beta antibody therapy in a rat model
    • Guan Q., Li S., Gao S., Chen H., Nguan C.Y., Du C. Reduction of chronic rejection of renal allografts by anti-transforming growth factor-beta antibody therapy in a rat model. Am J Physiol Renal Physiol 2013, 305:F199-F207.
    • (2013) Am J Physiol Renal Physiol , vol.305
    • Guan, Q.1    Li, S.2    Gao, S.3    Chen, H.4    Nguan, C.Y.5    Du, C.6
  • 64
    • 0025204364 scopus 로고
    • Percutaneous needle biopsy of the renal allograft. A clinical safety evaluation of 1129 biopsies
    • Wilczek H.E. Percutaneous needle biopsy of the renal allograft. A clinical safety evaluation of 1129 biopsies. Transplantation 1990, 50:790-797.
    • (1990) Transplantation , vol.50 , pp. 790-797
    • Wilczek, H.E.1
  • 66
    • 0141845131 scopus 로고    scopus 로고
    • Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates
    • Furness P.N., Philpott C.M., Chorbadjian M.T., et al. Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates. Transplantation 2003, 76:969-973.
    • (2003) Transplantation , vol.76 , pp. 969-973
    • Furness, P.N.1    Philpott, C.M.2    Chorbadjian, M.T.3
  • 67
    • 0037182920 scopus 로고    scopus 로고
    • Subclinical rejection in tacrolimus-treated renal transplant recipients
    • Gloor J.M., Cohen A.J., Lager D.J., et al. Subclinical rejection in tacrolimus-treated renal transplant recipients. Transplantation 2002, 73:1965-1968.
    • (2002) Transplantation , vol.73 , pp. 1965-1968
    • Gloor, J.M.1    Cohen, A.J.2    Lager, D.J.3
  • 68
    • 40449090625 scopus 로고    scopus 로고
    • National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, U.S.Renal Data System
    • U.S.Renal Data System USRDS 2007 Annual Data Report: Atlas of End-Stage Renal Disease in the United States 2007, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
    • (2007) USRDS 2007 Annual Data Report: Atlas of End-Stage Renal Disease in the United States
  • 69
    • 84893583540 scopus 로고    scopus 로고
    • Urinary cell mRNA profiles predictive of human kidney allograft status
    • Lee J.R., Muthukumar T., Dadhania D., et al. Urinary cell mRNA profiles predictive of human kidney allograft status. Immunol Rev 2014, 258:218-240.
    • (2014) Immunol Rev , vol.258 , pp. 218-240
    • Lee, J.R.1    Muthukumar, T.2    Dadhania, D.3
  • 70
    • 0035967217 scopus 로고    scopus 로고
    • Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine
    • Li B., Hartono C., Ding R., et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 2001, 344:947-954.
    • (2001) N Engl J Med , vol.344 , pp. 947-954
    • Li, B.1    Hartono, C.2    Ding, R.3
  • 71
    • 0037469042 scopus 로고    scopus 로고
    • CD103 mRNA levels in urinary cells predict acute rejection of renal allografts
    • Ding R., Li B., Muthukumar T., et al. CD103 mRNA levels in urinary cells predict acute rejection of renal allografts. Transplantation 2003, 75:1307-1312.
    • (2003) Transplantation , vol.75 , pp. 1307-1312
    • Ding, R.1    Li, B.2    Muthukumar, T.3
  • 72
    • 0038586415 scopus 로고    scopus 로고
    • Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts
    • Muthukumar T., Ding R., Dadhania D., et al. Serine proteinase inhibitor-9, an endogenous blocker of granzyme B/perforin lytic pathway, is hyperexpressed during acute rejection of renal allografts. Transplantation 2003, 75:1565-1570.
    • (2003) Transplantation , vol.75 , pp. 1565-1570
    • Muthukumar, T.1    Ding, R.2    Dadhania, D.3
  • 73
    • 2442652560 scopus 로고    scopus 로고
    • Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine
    • Tatapudi R.R., Muthukumar T., Dadhania D., et al. Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine. Kidney Int 2004, 65:2390-2397.
    • (2004) Kidney Int , vol.65 , pp. 2390-2397
    • Tatapudi, R.R.1    Muthukumar, T.2    Dadhania, D.3
  • 74
    • 28244444532 scopus 로고    scopus 로고
    • Messenger RNA for FOXP3 in the urine of renal-allograft recipients
    • Muthukumar T., Dadhania D., Ding R., et al. Messenger RNA for FOXP3 in the urine of renal-allograft recipients. N Engl J Med 2005, 353:2342-2351.
    • (2005) N Engl J Med , vol.353 , pp. 2342-2351
    • Muthukumar, T.1    Dadhania, D.2    Ding, R.3
  • 75
    • 78650842077 scopus 로고    scopus 로고
    • Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts
    • Afaneh C., Muthukumar T., Lubetzky M., et al. Urinary cell levels of mRNA for OX40, OX40L, PD-1, PD-L1, or PD-L2 and acute rejection of human renal allografts. Transplantation 2010, 90:1381-1387.
    • (2010) Transplantation , vol.90 , pp. 1381-1387
    • Afaneh, C.1    Muthukumar, T.2    Lubetzky, M.3
  • 76
    • 3042614142 scopus 로고    scopus 로고
    • Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection
    • Kotsch K., Mashreghi M.F., Bold G., et al. Enhanced granulysin mRNA expression in urinary sediment in early and delayed acute renal allograft rejection. Transplantation 2004, 77:1866-1875.
    • (2004) Transplantation , vol.77 , pp. 1866-1875
    • Kotsch, K.1    Mashreghi, M.F.2    Bold, G.3
  • 77
    • 0034103626 scopus 로고    scopus 로고
    • Prospects and applicability of molecular diagnosis of allograft rejection
    • Strom T.B., Suthanthiran M. Prospects and applicability of molecular diagnosis of allograft rejection. Semin Nephrol 2000, 20:103-107.
    • (2000) Semin Nephrol , vol.20 , pp. 103-107
    • Strom, T.B.1    Suthanthiran, M.2
  • 78
    • 0142092636 scopus 로고    scopus 로고
    • Optimization of RNA yield, purity and mRNA copy number by treatment of urine cell pellets with RNAlater
    • Medeiros M., Sharma V.K., Ding R., et al. Optimization of RNA yield, purity and mRNA copy number by treatment of urine cell pellets with RNAlater. J Immunol Methods 2003, 279:135-142.
    • (2003) J Immunol Methods , vol.279 , pp. 135-142
    • Medeiros, M.1    Sharma, V.K.2    Ding, R.3
  • 79
    • 0026009177 scopus 로고
    • Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction
    • Li B., Sehajpal P.K., Khanna A., et al. Differential regulation of transforming growth factor beta and interleukin 2 genes in human T cells: demonstration by usage of novel competitor DNA constructs in the quantitative polymerase chain reaction. J Exp Med 1991, 174:1259-1262.
    • (1991) J Exp Med , vol.174 , pp. 1259-1262
    • Li, B.1    Sehajpal, P.K.2    Khanna, A.3
  • 80
    • 0037109004 scopus 로고    scopus 로고
    • Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine
    • Ding R., Medeiros M., Dadhania D., et al. Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine. Transplantation 2002, 74:987-994.
    • (2002) Transplantation , vol.74 , pp. 987-994
    • Ding, R.1    Medeiros, M.2    Dadhania, D.3
  • 81
    • 0027324601 scopus 로고
    • Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells
    • Cepek K.L., Parker C.M., Madara J.L., Brenner M.B. Integrin alpha E beta 7 mediates adhesion of T lymphocytes to epithelial cells. J Immunol 1993, 150:3459-3470.
    • (1993) J Immunol , vol.150 , pp. 3459-3470
    • Cepek, K.L.1    Parker, C.M.2    Madara, J.L.3    Brenner, M.B.4
  • 82
    • 0031572578 scopus 로고    scopus 로고
    • The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL
    • Hadley G.A., Bartlett S.T., Via C.S., Rostapshova E.A., Moainie S. The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL. J Immunol 1997, 159:3748-3756.
    • (1997) J Immunol , vol.159 , pp. 3748-3756
    • Hadley, G.A.1    Bartlett, S.T.2    Via, C.S.3    Rostapshova, E.A.4    Moainie, S.5
  • 83
    • 0035956734 scopus 로고    scopus 로고
    • Tubulitis after renal transplantation: demonstration of an association between CD103+ T cells, transforming growth factor beta1 expression and rejection grade
    • Robertson H., Wong W.K., Talbot D., Burt A.D., Kirby J.A. Tubulitis after renal transplantation: demonstration of an association between CD103+ T cells, transforming growth factor beta1 expression and rejection grade. Transplantation 2001, 71:306-313.
    • (2001) Transplantation , vol.71 , pp. 306-313
    • Robertson, H.1    Wong, W.K.2    Talbot, D.3    Burt, A.D.4    Kirby, J.A.5
  • 85
    • 0034694024 scopus 로고    scopus 로고
    • Requirement of the chemokine receptor CXCR3 for acute allograft rejection
    • Hancock W.W., Lu B., Gao W., et al. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med 2000, 192:1515-1520.
    • (2000) J Exp Med , vol.192 , pp. 1515-1520
    • Hancock, W.W.1    Lu, B.2    Gao, W.3
  • 87
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005, 6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 88
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca L., Cobbold S.P., Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med 2002, 195:1641-1646.
    • (2002) J Exp Med , vol.195 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 89
    • 17144393320 scopus 로고    scopus 로고
    • Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
    • Lee I., Wang L., Wells A.D., Dorf M.E., Ozkaynak E., Hancock W.W. Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med 2005, 201:1037-1044.
    • (2005) J Exp Med , vol.201 , pp. 1037-1044
    • Lee, I.1    Wang, L.2    Wells, A.D.3    Dorf, M.E.4    Ozkaynak, E.5    Hancock, W.W.6
  • 90
    • 59849096875 scopus 로고    scopus 로고
    • OX40 costimulation prevents allograft acceptance induced by CD40-CD40L blockade
    • Burrell B.E., Lu G., Li X.C., Bishop D.K. OX40 costimulation prevents allograft acceptance induced by CD40-CD40L blockade. J Immunol 2009, 182:379-390.
    • (2009) J Immunol , vol.182 , pp. 379-390
    • Burrell, B.E.1    Lu, G.2    Li, X.C.3    Bishop, D.K.4
  • 91
    • 70350433514 scopus 로고    scopus 로고
    • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
    • Fife B.T., Pauken K.E., Eagar T.N., et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat Immunol 2009, 10:1185-1192.
    • (2009) Nat Immunol , vol.10 , pp. 1185-1192
    • Fife, B.T.1    Pauken, K.E.2    Eagar, T.N.3
  • 92
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments
    • Bustin S.A., Benes V., Garson J.A., et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 2009, 55:611-622.
    • (2009) Clin Chem , vol.55 , pp. 611-622
    • Bustin, S.A.1    Benes, V.2    Garson, J.A.3
  • 93
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen T.D., Livak K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 2008, 3:1101-1108.
    • (2008) Nat Protoc , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2
  • 94
    • 33846647537 scopus 로고    scopus 로고
    • Commonly used reference genes are actively regulated in in vitro stimulated lymphocytes
    • Roge R., Thorsen J., Torring C., Ozbay A., Moller B.K., Carstens J. Commonly used reference genes are actively regulated in in vitro stimulated lymphocytes. Scand J Immunol 2007, 65:202-209.
    • (2007) Scand J Immunol , vol.65 , pp. 202-209
    • Roge, R.1    Thorsen, J.2    Torring, C.3    Ozbay, A.4    Moller, B.K.5    Carstens, J.6
  • 95
    • 84862298374 scopus 로고    scopus 로고
    • Discovery and validation of a molecular signature for the noninvasive diagnosis of human renal allograft fibrosis
    • Anglicheau D., Muthukumar T., Hummel A., et al. Discovery and validation of a molecular signature for the noninvasive diagnosis of human renal allograft fibrosis. Transplantation 2012, 93:1136-1146.
    • (2012) Transplantation , vol.93 , pp. 1136-1146
    • Anglicheau, D.1    Muthukumar, T.2    Hummel, A.3
  • 96
    • 84879540321 scopus 로고    scopus 로고
    • Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling
    • Keslar K.S., Lin M., Zmijewska A.A., et al. Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling. Am J Transplant 2013, 13:1891-1897.
    • (2013) Am J Transplant , vol.13 , pp. 1891-1897
    • Keslar, K.S.1    Lin, M.2    Zmijewska, A.A.3
  • 97
    • 49249087744 scopus 로고    scopus 로고
    • Noninvasive prediction of organ graft rejection and outcome using gene expression patterns
    • Anglicheau D., Suthanthiran M. Noninvasive prediction of organ graft rejection and outcome using gene expression patterns. Transplantation 2008, 86:192-199.
    • (2008) Transplantation , vol.86 , pp. 192-199
    • Anglicheau, D.1    Suthanthiran, M.2


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