Protective mechanism of lignans from Phyllanthus amarus against galactosamine/ lipopolysaccharide-induced hepatitis: An in-vivo and in-silico studies

Current Topics in Medicinal Chemistry

Volumn 14, Issue 8, 2014, Pages 1045-1055

  Bawankule, Dnyaneshwar U ^a   Trivedi, Priyanka ^a   Pal, Anirban ^a   Shanker, Karuna ^a   Singh, Manju ^a   Sharma, Pooja ^a   Khan, Feroz ^a   Maurya, Anil K ^a   Verma, Ram K ^a   Gupta, Madan M ^a  

^a CSIR CENTRAL INSTITUTE OF MEDICINAL AND AROMATIC PLANTS   (India)

Author keywords

Hepatoprotective; Inflammation; Lignans; Mice; Molecular docking; Phyllanthus amarus

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CATALASE; DICLOFENAC; GALACTOSAMINE; HYPOPHYLLANTHIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIGNAN; LIPOPOLYSACCHARIDE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NIRANTHIN; NIRTETRALIN; PHYLLANTHIN; PLANT MEDICINAL PRODUCT; SILYMARIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRGATUSIN; ANTIOXIDANT; CYTOKINE;

ACUTE HEPATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILIRUBIN BLOOD LEVEL; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; COLORIMETRY; COMPUTER MODEL; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DOSE COMPARISON; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; MALE; MOLECULAR DOCKING; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; TOXIC HEPATITIS; ANIMAL; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG-INDUCED LIVER INJURY; METABOLISM; PHYLLANTHUS; TOXICITY;

ANIMALS; ANTIOXIDANTS; COMPUTER SIMULATION; CYTOKINES; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; LIGNANS; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; MICE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; PHYLLANTHUS;

EID: 84903694059     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/1568026614666140324130047     Document Type: Article

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