Antiinflammatory and antiallodynic actions of the lignan niranthin isolated from Phyllanthus amarus. Evidence for interaction with platelet activating factor receptor

European Journal of Pharmacology

Volumn 546, Issue 1-3, 2006, Pages 182-188

  Kassuya, Cândida A L ^a   Silvestre, Aline ^b   Menezes de Lima Jr , Octávio ^a   Marotta, Denise Mollica ^a   Rehder, Vera Lúcia G ^b   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

(Rodent); Inflammation; Lignan; Niranthin; Phyllanthus amarus; Platelet activating factor receptor

Indexed keywords

BEPAFANT; MYELOPEROXIDASE; NIRANTHIN; NIRTETRALIN; PHYLLANTHUS AMARUS EXTRACT; PHYLTETRALIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; IC 50; MALE; MOUSE; NONHUMAN; PAW EDEMA; PHYLLANTHUS AMARUS; PLEURISY; PRIORITY JOURNAL; RAT;

ANALGESICS; ANIMALS; ANISOLES; ANTI-INFLAMMATORY AGENTS; AZEPINES; BINDING, COMPETITIVE; CARRAGEENAN; CEREBRAL CORTEX; DIOXOLES; INFLAMMATION; LIGNANS; MALE; MICE; PAIN MEASUREMENT; PAIN THRESHOLD; PEROXIDASE; PHYLLANTHUS; PLANT EXTRACTS; PLATELET ACTIVATING FACTOR; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; PLEURISY; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; TETRAHYDRONAPHTHALENES; TIME FACTORS; TRIAZOLES;

EID: 33748323234     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.07.025     Document Type: Article

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