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Volumn 47, Issue 1, 2012, Pages 152-161

QSAR, docking and in vivo studies for immunomodulatory activity of isolated triterpenoids from Eucalyptus tereticornis and Gentiana kurroo

Author keywords

Docking; Immunomodulatory; QSAR; Triterpenoids

Indexed keywords

ANTIINFLAMMATORY AGENT; BOSWELLIC ACID; CICHORIC ACID; CYCLOOXYGENASE 2; EUCALYPTUS TERETICORNIS EXTRACT; GENTIANA KURROO EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; LEVAMISOLE; LUPEOL; PLANT EXTRACT; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; URSOLIC ACID;

EID: 84862299873     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.05.009     Document Type: Article
Times cited : (40)

References (34)
  • 1
    • 0022834814 scopus 로고
    • Immunomodulating agents of plant origin I: Preliminary screening
    • C.K. Atal, M.L. Sharma, A. Kaul, and A. Khajuria Immunomodulating agents of plant origin I: preliminary screening J. Ethnopharmacol. 18 1986 133 141
    • (1986) J. Ethnopharmacol. , vol.18 , pp. 133-141
    • Atal, C.K.1    Sharma, M.L.2    Kaul, A.3    Khajuria, A.4
  • 2
    • 78951476685 scopus 로고    scopus 로고
    • Isolation, structural elucidation and immunomodulatory activity of fructans from aged garlic extract
    • P.M. Chandrashekar, K.V. Prashanth, and Y.P. Venkatesh Isolation, structural elucidation and immunomodulatory activity of fructans from aged garlic extract Phytochemistry 72 2011 255 265
    • (2011) Phytochemistry , vol.72 , pp. 255-265
    • Chandrashekar, P.M.1    Prashanth, K.V.2    Venkatesh, Y.P.3
  • 3
    • 0041379649 scopus 로고    scopus 로고
    • Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species
    • L.C. Chiang, L.T. Ng, W. Chiang, M.Y. Chang, Chun-Ching, and C.C. Lin Immunomodulatory activities of flavonoids, monoterpenoids, triterpenoids, iridoid glycosides and phenolic compounds of Plantago species Planta Med. 69 2003 600 604
    • (2003) Planta Med. , vol.69 , pp. 600-604
    • Chiang, L.C.1    Ng, L.T.2    Chiang, W.3    Chang, M.Y.4    Chun-Ching5    Lin, C.C.6
  • 7
    • 0034609833 scopus 로고    scopus 로고
    • Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties
    • P. Ertl, B. Rohde, and P. Selzer Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties J. Med. Chem. 43 2000 3714 3717
    • (2000) J. Med. Chem. , vol.43 , pp. 3714-3717
    • Ertl, P.1    Rohde, B.2    Selzer, P.3
  • 8
    • 67649126476 scopus 로고    scopus 로고
    • Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: Why they are needed and how they might work
    • D.S. Fedson Confronting the next influenza pandemic with anti-inflammatory and immunomodulatory agents: why they are needed and how they might work Influenza Resp. Viruses 3 2009 129 142
    • (2009) Influenza Resp. Viruses , vol.3 , pp. 129-142
    • Fedson, D.S.1
  • 9
    • 26444436361 scopus 로고    scopus 로고
    • Immunomodulatory effects of seabuckthorn (Hippophae rhamnoides L.) against chromium (VI) induced immunosuppression
    • S. Geetha, V. Singh, M.S. Ram, G. Ilavazhagan, P.K. Banerjee, and R.C. Sawhney Immunomodulatory effects of seabuckthorn (Hippophae rhamnoides L.) against chromium (VI) induced immunosuppression Mol. Cell Biochem. 278 2005 101 109
    • (2005) Mol. Cell Biochem. , vol.278 , pp. 101-109
    • Geetha, S.1    Singh, V.2    Ram, M.S.3    Ilavazhagan, G.4    Banerjee, P.K.5    Sawhney, R.C.6
  • 10
    • 0024235988 scopus 로고
    • Ocimum sanctum - A preliminary study evaluating its immunoregulatory profile in albino rats
    • S. Godhwani, J.L. Godhwani, and D.S. Was Ocimum sanctum - a preliminary study evaluating its immunoregulatory profile in albino rats J. Ethnopharmacol. 24 1988 193 198
    • (1988) J. Ethnopharmacol. , vol.24 , pp. 193-198
    • Godhwani, S.1    Godhwani, J.L.2    Was, D.S.3
  • 11
    • 34347266530 scopus 로고    scopus 로고
    • Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn
    • S. Imam, I. Azhar, M.M. Hasan, M.S. Ali, and S.W. Ahmed Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn Pak. J. Pharm. Sci. 20 2007 125 127
    • (2007) Pak. J. Pharm. Sci. , vol.20 , pp. 125-127
    • Imam, S.1    Azhar, I.2    Hasan, M.M.3    Ali, M.S.4    Ahmed, S.W.5
  • 12
    • 33847027186 scopus 로고    scopus 로고
    • Immunomodulatory effects of two sapogenins 1 and 2 isolated from Luffa cylindrica in Balb/C mice
    • A. Khajuria, Gupta, S. Garaib, and B.P. Wakhloo Immunomodulatory effects of two sapogenins 1 and 2 isolated from Luffa cylindrica in Balb/C mice Bioorg. Med. Chem. Lett. 17 2007 1608 1612
    • (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 1608-1612
    • Khajuria, A.1    Gupta2    Garaib, S.3    Wakhloo, B.P.4
  • 14
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • C.A. Lipinski, F. Lombardo, B.W. Dominy, and P.J. Feeney Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings Adv. Drug Deliv. Rev. 46 2001 3 26
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 15
    • 67650267721 scopus 로고    scopus 로고
    • Triterpene glycosides from the underground parts of Caulophyllum thalictroides
    • Y. Matsuo, K. Watanabe, and Y. Mimaki Triterpene glycosides from the underground parts of Caulophyllum thalictroides J. Nat. Prod. 72 2009 1155 1160
    • (2009) J. Nat. Prod. , vol.72 , pp. 1155-1160
    • Matsuo, Y.1    Watanabe, K.2    Mimaki, Y.3
  • 17
    • 0033673508 scopus 로고    scopus 로고
    • A knowledge-based scoring function for protein-ligand interactions: Probing the reference state
    • I.A. Muegge A knowledge-based scoring function for protein-ligand interactions: probing the reference state Perspect. Drug Discovery Des. 20 2000 99 114
    • (2000) Perspect. Drug Discovery Des. , vol.20 , pp. 99-114
    • Muegge, I.A.1
  • 18
    • 0033545622 scopus 로고    scopus 로고
    • A general and fast scoring function for protein-ligand interactions: A simplified potential approach
    • I. Muegge, and Y.C. Martin A general and fast scoring function for protein-ligand interactions: a simplified potential approach J. Med. Chem. 42 1999 791 804
    • (1999) J. Med. Chem. , vol.42 , pp. 791-804
    • Muegge, I.1    Martin, Y.C.2
  • 19
    • 0032979004 scopus 로고    scopus 로고
    • Theoretical calculation and prediction of intestinal absorption of drugs in humans using MolSurf parametrization and PLS statistics
    • U. Norinder, T. Osterberg, and P. Artursson Theoretical calculation and prediction of intestinal absorption of drugs in humans using MolSurf parametrization and PLS statistics Eur. J. Pharm. Sci 8 1999 49 56
    • (1999) Eur. J. Pharm. Sci , vol.8 , pp. 49-56
    • Norinder, U.1    Osterberg, T.2    Artursson, P.3
  • 21
    • 33745611216 scopus 로고
    • The so-called Eucalyptus hybrid of Mysore origine
    • M. Qureshi The so-called Eucalyptus hybrid of Mysore origine Indian Forester 92 1966 213 217
    • (1966) Indian Forester , vol.92 , pp. 213-217
    • Qureshi, M.1
  • 23
    • 84859040914 scopus 로고
    • Eucalyptus oil potential from large-scale plantations
    • H.S. Rao, M.P. Shiva, and P.P. Jain Eucalyptus oil potential from large-scale plantations Indian Forester 96 1970 135 140
    • (1970) Indian Forester , vol.96 , pp. 135-140
    • Rao, H.S.1    Shiva, M.P.2    Jain, P.P.3
  • 24
    • 0034811190 scopus 로고    scopus 로고
    • Immunomodulatory activity of Punica granatum in rabbits - A preliminary study
    • R.G. Ross, S. Selvasubramanian, and S. Jayasundar Immunomodulatory activity of Punica granatum in rabbits - a preliminary study J. Ethnopharmacol. 78 2001 85 87
    • (2001) J. Ethnopharmacol. , vol.78 , pp. 85-87
    • Ross, R.G.1    Selvasubramanian, S.2    Jayasundar, S.3
  • 25
    • 0142087956 scopus 로고    scopus 로고
    • 13C NMR resonances of oleanolic acid, 18α-oleanolic acid, ursolic acid and their 11-oxo derivatives
    • 13C NMR resonances of oleanolic acid, 18α-oleanolic acid, ursolic acid and their 11-oxo derivatives Magn. Reson. Chem. 41 2003 636 638
    • (2003) Magn. Reson. Chem. , vol.41 , pp. 636-638
    • Seebacher, W.1    Simic, N.2    Weis, R.3    Saf, R.4    Kunert, O.5
  • 26
    • 0000276934 scopus 로고
    • In vitro propagation of Gentiana kurroo an indigenous threatened plant of medicinal importance
    • N. Sharma, K.P.S. Chandal, and A. Paul In vitro propagation of Gentiana kurroo an indigenous threatened plant of medicinal importance Plant Cell Tissue Organ Cult. 34 1993 307 309
    • (1993) Plant Cell Tissue Organ Cult. , vol.34 , pp. 307-309
    • Sharma, N.1    Chandal, K.P.S.2    Paul, A.3
  • 31
    • 0034729673 scopus 로고    scopus 로고
    • QSAR model for drug human oral bioavailability
    • F. Yoshida, and J.G. Topliss QSAR model for drug human oral bioavailability J. Med. Chem. 43 2000 2575 2585
    • (2000) J. Med. Chem. , vol.43 , pp. 2575-2585
    • Yoshida, F.1    Topliss, J.G.2
  • 32
    • 33947228423 scopus 로고    scopus 로고
    • Antitumor agents 252. Application of validated QSAR models to database mining: Discovery of novel tylophorine derivatives as potential anticancer agents
    • S.X. Zhang, L.Y. Wei, K. Bastow, W.F. Zheng, A. Brossi, K.H. Lee, and A. Tropsha Antitumor agents 252. Application of validated QSAR models to database mining: Discovery of novel tylophorine derivatives as potential anticancer agents J. Comput. Aided Mol. Des. 21 2007 97 112
    • (2007) J. Comput. Aided Mol. Des. , vol.21 , pp. 97-112
    • Zhang, S.X.1    Wei, L.Y.2    Bastow, K.3    Zheng, W.F.4    Brossi, A.5    Lee, K.H.6    Tropsha, A.7
  • 33
    • 0034797192 scopus 로고    scopus 로고
    • Three new sesquiterpene glycosides from Dendrobium nobile with immunomodulatory activity
    • W. Zhao, Q. Ye, X. Tan, H. Jiang, X. Li, K. Chen, and A.D. Kinghorn Three new sesquiterpene glycosides from Dendrobium nobile with immunomodulatory activity J. Nat. Prod. 64 2001 1196 1200
    • (2001) J. Nat. Prod. , vol.64 , pp. 1196-1200
    • Zhao, W.1    Ye, Q.2    Tan, X.3    Jiang, H.4    Li, X.5    Chen, K.6    Kinghorn, A.D.7
  • 34
    • 0000378338 scopus 로고    scopus 로고
    • Novel variable selection quantitative structure-property relationship approach based on the k-nearest-neighbor principle
    • W. Zheng, and A. Tropsha Novel variable selection quantitative structure-property relationship approach based on the k-nearest-neighbor principle J. Chem. Inf. Comput. Sci 40 2000 185 194
    • (2000) J. Chem. Inf. Comput. Sci , vol.40 , pp. 185-194
    • Zheng, W.1    Tropsha, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.