Sensory-motor performance after acute glutathione depletion by l-buthionine sulfoximine injection into substantia nigra pars compacta

Behavioural Brain Research

Volumn 271, Issue , 2014, Pages 286-293

  Díaz Hung, Mei Li ^a   Blanco, Lisette ^a   Pavón, Nancy ^a   León, Rilda ^a   Estupiñan, Bárbara ^a   Orta, Eduardo ^a   Martínez, Klaudia ^b   Fernández, Isabel ^a  

^a CENTRO INTERNACIONAL DE RESTAURACIÓN NEUROLÓGICA CIREN   (Cuba)

^b UNIVERSITY OF HAVANA   (Cuba)

Author keywords

Antioxidant enzymes; Astrocytes; Dopaminergic cell; Glutathione; Malondialdehyde; Sensory motor function

Indexed keywords

BUTHIONINE SULFOXIMINE; CATALASE; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; TYROSINE 3 MONOOXYGENASE;

ADHESIVE REMOVAL TEST; AEROBIC METABOLISM; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; CORPUS STRIATUM; DEPLETION; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; GLUTATHIONE DEPLETION; IMMUNOHISTOCHEMISTRY; MALE; NERVE DEGENERATION; NEUROLOGIC EXAMINATION; NEUROPATHOLOGY; NONHUMAN; OPEN FIELD BEHAVIOR; OPEN FIELD TEST; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SENSORIMOTOR FUNCTION; SENSORIMOTOR NEUROPATHY; STAIRCASE TEST; SUBSTANTIA NIGRA PARS COMPACTA; TASK PERFORMANCE; TRAVERSE BEAM TEST; ANIMAL; DRUG EFFECTS; LOCOMOTION; METABOLISM; MICROINJECTION; MOTOR ACTIVITY; PSYCHOMOTOR PERFORMANCE; SPRAGUE DAWLEY RAT;

ANIMALS; BUTHIONINE SULFOXIMINE; CORPUS STRIATUM; DOPAMINERGIC NEURONS; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTATHIONE; LOCOMOTION; MALE; MICROINJECTIONS; MOTOR ACTIVITY; PARS COMPACTA; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY; TYROSINE 3-MONOOXYGENASE;

EID: 84903689215     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2014.05.066     Document Type: Article

References (58)

1. Aebi H. Catalase in vitro. Methods Enzymol 1984, 105:121-126.
2. Alcalay R.N., Mejia-Santana H., Tang M.X., Rosado L., Verbitsky M., Kisselev S., et al. Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease. Arch Neurol 2009, 66:1517-1522.
3. Almaguer-Melian W., Cruz-Aguado R., Bergado J.A. Synaptic plasticity is impaired in rats with a low glutathione content. Synapse 2000, 38:369-374.
4. Avshalumov M.V., Chen B.T., Koos T., Tepper J.M., Rice M.E. Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels. J Neurosci 2005, 25:4222-4231.
5. Ballatori N., Krance S.M., Notenboom S., Shi S., Tieu K., Hammond C.L. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem 2009, 390:191-214.
6. Binukumar B.K., Bal A., Kandimalla R.J., Gill K.D. Nigrostriatal neuronal death following chronic dichlorvos exposure: crosstalk between mitochondrial impairments, alpha synuclein aggregation, oxidative damage and behavioral changes. Mol Brain 2010, 3:35. 10.1186/1756-6606-3-35.
7. Boll M.C., Alcaraz-Zubeldia M., Rios C. Medical management of Parkinson's disease: focus on neuroprotection. Curr Neuropharmacol 2011, 9:350-359.
8. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
9. Brambilla D., Mancuso C., Scuderi M.R., Bosco P., Cantarella G., Lempereur L., et al. The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile. Nutr J 2008, 7:29. 10.1186/1475-2891-7-29.
10. Brunk U.T., Terman A. The mitochondrial-lysosomal axis theory of aging: accumulation of damaged mitochondria as a result of imperfect autophagocytosis. Eur J Biochem 2002, 269:1996-2002.
11. Buege J.A., Aust S.D. Microsomal lipid peroxidation. Methods Enzymol 1978, 52:302-310.
12. Cabungcal J.H., Preissmann D., Delseth C., Cuenod M., Do K.Q., Schenk F. Transitory glutathione deficit during brain development induces cognitive impairment in juvenile and adult rats: relevance to schizophrenia. Neurobiol Dis 2007, 26:634-645.
13. Carlberg I., Mannervik B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J Biol Chem 1975, 250:5475-5480.
14. Chi L., Ke Y., Luo C., Gozal D., Liu R. Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. Neuroscience 2007, 144:991-1003.
15. Chinta S.J., Kumar M.J., Hsu M., Rajagopalan S., Kaur D., Rane A., et al. Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration. J Neurosci 2007, 19(27):13997-14006.
16. Circu M.L., Yee A.T. Glutathione and apoptosis. Free Radic Res 2008, 42:689-706.
17. Clark J., Gebhart G., Gonder J., Keeling M., Kohn D. The 1998 guide for the care and use of laboratory animals: rodent. ILAR J 1998, 38:1-35.
18. Correa F., Ljunggren E., Mallard C., Nilsson M., Weber S.G., Sandberg M. The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia: involvement of p38 MAPK. Glia 2011, 59:785-799.
19. Cruz-Aguado R., Almaguer-Melian W., Diaz C.M., Lorigados L., Bergado J. Behavioral and biochemical effects of glutathione depletion in the rat brain. Brain Res Bull 2001, 55:327-333.
20. Danielson S.R., Andersen J.K. Oxidative and nitrative protein modifications in Parkinson's disease. Free Radic Biol Med 2008, 44:1787-1794.
21. de B.S., Canals S., Casarejos M.J., Solano R.M., Menendez J., Mena M.A. Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures. J Neurochem 2004, 91:667-682.
22. Díaz-Hung M.L., González M., Fernández I., Horruitiner I., Piedra S. Oxidative damage alters memory consolidation in adult rats. Biotecnol Apl 2011, 28:250-254.
23. Dringen R., Gutterer J.M., Hirrlinger J. Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species. Eur J Biochem 2000, 267:4912-4916.
24. Du Z.X., Zhang H.Y., Meng X., Guan Y., Wang H.Q. Role of oxidative stress and intracellular glutathione in the sensitivity to apoptosis induced by proteasome inhibitor in thyroid cancer cells. BMC Cancer 2009, 9:56. 10.1186/1471-2407-9-56.
25. Flohe L., Gunzler W.A. Assays of glutathione peroxidase. Methods Enzymol 1984, 105:114-121.
26. García R., González M.E., Fernández I., Castaño Y., Díaz M.L., Alberti E. Behavioral and oxidative metabolism disorders in a model of transient induced cerebral hypoperfusion in rats. Biotecnol Apl 2008, 25:339-344.
27. Garcia-Garcia A., Zavala-Flores L., Rodriguez-Rocha H., Franco R. Thiol-redox signaling, dopaminergic cell death, and Parkinson's disease. Antioxid Redox Signal 2012, 17:1764-1784.
28. Garrido M., Tereshchenko Y., Zhevtsova Z., Taschenberger G., Bahr M., Kugler S. Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons. Acta Neuropathol 2011, 121:475-485.
29. González-Fraguela M.E., Díaz-Hung M.L., Vera H., Maragoto C., Noris E., Blanco L., et al. Oxidative stress markers in children with autism spectrum disorders. Br J Med Med Res 2013, 3:307-317.
30. Haskew-Layton R.E., Payappilly J.B., Smirnova N.A., Ma T.C., Chan K.K., Murphy T.H., et al. Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway. Proc Natl Acad Sci USA 2010, 107:17385-17390.
31. Higuchi Y. Glutathione depletion-induced chromosomal DNA fragmentation associated with apoptosis and necrosis. J Cell Mol Med 2004, 8:455-464.
32. Lv S.W., Wang X.G., Mu Y., Zang T.Z., Ji Y.T., Liu J.Q., et al. A novel dicyclodextrinyl diselenide compound with glutathione peroxidase activity. FEBS J 2007, 274:3846-3854.
33. McGeer P.L., McGeer E.G. Glial reactions in Parkinson's disease. Mov Disord 2008, 23:474-483.
34. Meredith G.E., Kang U.J. Behavioral models of Parkinson's disease in rodents: a new look at an old problem. Mov Disord 2006, 21:1595-1606.
35. Michel P.P., Ruberg M., Hirsch E. Dopaminergic neurons reduced to silence by oxidative stress: an early step in the death cascade in Parkinson's disease?. Sci STKE 2006, 2006:e19.
36. Molina-Luna K., Pekanovic A., Rohrich S., Hertler B., Schubring-Giese M., Rioult-Pedotti M.S., et al. Dopamine in motor cortex is necessary for skill learning and synaptic plasticity. PLoS ONE 2009, 4:e7082.
37. Montoya C.P., Campbell-Hope L.J., Pemberton K.D., Dunnett S.B. The "staircase test": a measure of independent forelimb reaching and grasping abilities in rats. J Neurosci Methods 1991, 36:219-228.
38. Ng C.F., Schafer F.Q., Buettner G.R., Rodgers V.G. The rate of cellular hydrogen peroxide removal shows dependency on GSH: mathematical insight into in vivo H2O2 and GPx concentrations. Free Radic Res 2007, 41:1201-1211.
39. Nikam S., Nikam P., Ahaley S.K., Sontakke A.V. Oxidative stress in Parkinson's disease. Indian J Clin Biochem 2009, 24:98-101.
40. Niu C., Mei J., Pan Q., Fu X. Nigral degeneration with inclusion body formation and behavioral changes in rats after proteasomal inhibition. Stereotact Funct Neurosurg 2009, 87:69-81.
41. Olferd E., Cross B., Mc Willian D., Mc Willian A. Guidelines for the use of animals in Psychology. Canadian Council on Animal Care (CCAC) 1997, 155-162. Ottawa, Bradda Printing Services Inc.
42. Olferd E., Cross B., Mc Willian D., Mc Willian A. Guidelines for the use of animal in Neuroscience research. Canadian Council on Care (CCAC) 1997, 163-165. Bradda Printing Services Inc., Ottawa.
43. Parpura V., Heneka M.T., Montana V., Oliet S.H., Schousboe A., Haydon P.G., et al. Glial cells in (patho)physiology. J Neurochem 2012, 121:4-27.
44. Patki G., Che Y., Lau Y.S. Mitochondrial dysfunction in the striatum of aged chronic mouse model of Parkinson's disease. Front Aging Neurosci 2009, 1:3. 10.3389/neuro.24.003.2009.
45. Paxinos G., Watson C. The rat brain in stereotaxic coordenates 1986, Second Academic Press.
46. Ren J.P., Zhao Y.W., Sun X.J. Toxic influence of chronic oral administration of paraquat on nigrostriatal dopaminergic neurons in C57BL/6 mice. Chin Med J (Engl) 2009, 122:2366-2371.
47. Rose F.D., Davey M.J., Love S., Dell P.A. Environmental enrichment and recovery from contralateral sensory neglect in rats with large unilateral neocortical lesions. Behav Brain Res 1987, 24:195-202.
48. Rougemont M., Do K.Q., Castagne V. New model of glutathione deficit during development: effect on lipid peroxidation in the rat brain. J Neurosci Res 2002, 70:774-783.
49. Schallert T. Behavioral test for preclinical intervention assessment. NeuroRx 2006, 3:497-504.
50. Schallert T., Whishaw I.Q. Bilateral cutaneous stimulation of the somatosensory system in hemidecorticate rats. Behav Neurosci 1984, 98:518-540.
51. Singh S., Ahmed R., Sagar R.K., Krishana B. Neuroprotection of the nigrostriatal dopaminergic neurons by melatonin in hemiparkinsonium rat. Indian J Med Res 2006, 124:419-426.
52. Smith M.P., Cass W.A. Oxidative stress and dopamine depletion in an intrastriatal 6-hydroxydopamine model of Parkinson's disease. Neuroscience 2007, 144:1057-1066.
53. Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969, 27:502-522.
54. Toffa S., Kunikowska G.M., Zeng B.Y., Jenner P., Marsden C.D. Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration. J Neural Transm 1997, 104:67-75.
55. Torres E.B., Heilman K.M., Poizner H. Impaired endogenously evoked automated reaching in Parkinson's disease. J Neurosci 2011, 31:17848-17863.
56. Truong L., Allbutt H., Kassiou M., Henderson J.M. Developing a preclinical model of Parkinson's disease: a study of behaviour in rats with graded 6-OHDA lesions. Behav Brain Res 2006, 169:1-9.
57. Wang X., Michaelis E.K. Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci 2010, 2:12. 10.3389/fnagi.2010.00012.
58. Zhou C., Huang Y., Przedborski S. Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Ann NY Acad Sci 2008, 1147:93-104. 10.1196/annals.1427.023.