Osthole attenuates doxorubicin-induced apoptosis in PC12 cells through inhibition of mitochondrial dysfunction and ROS production

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Shokoohinia, Yalda ^a   Hosseinzadeh, Leila ^a   Moieni Arya, Maryam ^a   Mostafaie, Ali ^b   Mohammadi Motlagh, Hamid Reza ^b  

^a KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b KERMANSHAH UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; COUMARIN DERIVATIVE; DOXORUBICIN; OSTHOLE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; PLANT EXTRACT;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG CYTOTOXICITY; ENZYME ACTIVITY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PC12 CELL LINE; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ADRENAL GLAND NEOPLASMS; ANIMAL; APIACEAE; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; PATHOLOGY; PHEOCHROMOCYTOMA;

ADRENAL GLAND NEOPLASMS; ANIMALS; APIACEAE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; COUMARINS; DOXORUBICIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; OXIDATIVE STRESS; PC12 CELLS; PHEOCHROMOCYTOMA; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REACTIVE OXYGEN SPECIES;

EID: 84903639565     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/156848     Document Type: Article

References (32)

1. Hosseinzadeh L., Behravan J., Mosaffa F., Bahrami G., Bahrami A., Karimi G., Curcumin potentiates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells through generation of reactive oxygen species. Food and Chemical Toxicology 2011 49 5 1102 1109 2-s2.0-79953042525 10.1016/j.fct.2011.01.021
2. Tangpong J., Miriyala S., Noel T., Sinthupibulyakit C., Jungsuwadee P., St. Clair D. K., Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia mangostana. Neuroscience 2011 175 292 299 2-s2.0-78951481922 10.1016/j.neuroscience.2010.11.007
3. Angelo Lopes M., Meisel A., Dirnagl U., Carvalho F. D., Bastos M. D. L., Doxorubicin induces biphasic neurotoxicity to rat cortical neurons. NeuroToxicology 2008 29 2 286 293 2-s2.0-39749200035 10.1016/j.neuro.2007.12.003
4. 2+-induced permeability transition and oxidative damage. Free Radical Biology and Medicine 2008 45 10 1395 1402 2-s2.0-54349099428 10.1016/j.freeradbiomed.2008.08.008
5. Klaassen C. D., Casarett & Doull's Toxicology 2007 7th McGraw Hill
6. Park E.-S., Kim S.-D., Lee M.-H., Lee H.-S. S., Lee I.-S., Sung J.-K., Yoon Y.-S., Protective effects of N-acetylcysteine and selenium against doxorubicin toxicity in rats. Journal of Veterinary Science 2003 4 2 129 136 2-s2.0-1542439108
7. Moreira P. I., Smith M. A., Zhu X., Nunomura A., Castellani R. J., Perry G., Oxidative stress and neurodegeneration. Annals of the New York Academy of Sciences 2005 1043 545 552 2-s2.0-23744439419 10.1196/annals.1333.062 (Pubitemid 41123944)
8. Naseri M., Monsef- Esfehani H. R., Saeidnia S., Dastan D., Gohari A. R., Antioxidative coumarins from the roots of Ferulago subvelutina. Asian Journal of Chemistry 2013 25 4 1875 1878 2-s2.0-84875170841
9. Kahkeshani N., Farahaniki B., Mahdaviani P., Abdolghaffari A., Hassanzadeh G., Abdollahi M., Khanavi M., Antioxidant and burn healing potential of Galium odoratum extracts. Research in Pharmaceutical Sciences 2013 8 3 197 203 2-s2.0-84873336122
10. Liu C., Gong K., Mao X., Li W., Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human Hepatocellular carcinoma. International Journal of Cancer 2011 129 6 1519 1531 2-s2.0-79959757676 10.1002/ijc.25817
11. Sadraei H., Shokoohinia Y., Sajjadi S. E., Mozafari M., Antispasmodic effects of Prangos ferulacea acetone extract and its main component osthole on ileum contraction. Research in Pharmaceutical Sciences 2013 8 2 137 144 2-s2.0-84873357270
12. Luszczki J. J., Andres-Mach M., Cisowski W., Mazol I., Glowniak K., Czuczwar S. J., Osthole suppresses seizures in the mouse maximal electroshock seizure model. European Journal of Pharmacology 2009 607 1-3 107 109 2-s2.0-62149147196 10.1016/j.ejphar.2009.02.022
13. Ogawa H., Sasai N., Kamisako T., Baba K., Effects of osthol on blood pressure and lipid metabolism in stroke-prone spontaneously hypertensive rats. Journal of Ethnopharmacology 2007 112 1 26 31 2-s2.0-34247889815 10.1016/j.jep.2007.01.028 (Pubitemid 46702410)
14. Chao X., Zhou J., Chen T., Liu W., Dong W., Qu Y., Jiang X., Ji X., Zhen H., Fei Z., Neuroprotective effect of osthole against acute ischemic stroke on middle cerebral ischemia occlusion in rats. Brain Research 2010 1363 206 211 2-s2.0-78149469425 10.1016/j.brainres.2010.09.052
15. +-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production. Neurochemistry International 2010 57 3 206 215 2-s2.0-77955092871 10.1016/j.neuint.2010.05.011
16. Xiao H., Yue-Jiang C., Wen L., Reversal effect of osthole on adriamycin resistance in human breast cancer cells. Chinese Journal of Hospital Pharmacy 2011 12 990 993
17. Hatanaka H., Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line. Brain Research 1981 222 2 225 233 2-s2.0-0019354927 10.1016/0006-8993(81)91029-5 (Pubitemid 11000335)
18. Rebois R. V., Reynolds E. E., Toll L., Howard B. D., Storage of dopamine and acetylcholine in granules of PC12, a clonal pheochromocytoma cell line. Biochemistry 1980 19 6 1240 1248 2-s2.0-0019308385 (Pubitemid 10033206)
19. You L., An R., Wang X., Li Y., Discovery of novel osthole derivatives as potential anti-breast cancer treatment. Bioorganic and Medicinal Chemistry Letters 2010 20 24 7426 7428 2-s2.0-78449298875 10.1016/j.bmcl.2010.10.027
20. Sajjadi S. E., Zeinvand H., Shokoohinia Y., Isolation and identification of osthol from the fruits and essential oil composition of the leaves of Prangos asperula Boiss. Research in Pharmaceutical Sciences 2009 4 1 19 23 2-s2.0-74549115954
21. Sajjadi S. E., Shokoohinia Y., Hemmati S., Isolation and identification of furanocoumarins and a phenylpropanoid from the acetone extract and identification of volatile constituents from the essential oil of Peucedanum pastinacifolium. Chemistry of Natural Compounds 2012 48 4 668 671 2-s2.0-84865800650 10.1007/s10600-012-0343-9
22. +-induced cytotoxicity in PC12 cells via inhibition of mitochondrial dysfunction and ROS production. Neurochemistry International 2010 57 3 206 215 2-s2.0-77955092871 10.1016/j.neuint.2010.05.011
23. 2+ concentration. European Journal of Pharmacology 2011 650 1 41 47 2-s2.0-78649726904 10.1016/j.ejphar.2010.09.049
24. Mojarrab M., Jamshidi M., Ahmadi F., Aliadeh E., Hosseinzadeh L., Extracts of Artemisia ciniformis protect cytotoxicity induced by hydrogen peroxide in H9c2 cardiac muscle cells through the inhibition of reactive oxygen species. Advances in Pharmacological Sciences 2013 2013 5 141683 10.1155/2013/141683
25. Hosseinzadeh L., Behravan J., Mosaffa F., Bahrami G., Bahrami A. R., Karimi G., Effect of curcumin on doxorubicin-induced cytotoxicity in h9c2 cardiomyoblast cells. Iranian Journal of Basic Medical Sciences 2011 14 1 49 56 2-s2.0-78651404983
26. Keen C. L., Chocolate: food as medicine/medicine as food. Journal of the American College of Nutrition 2001 20 5, supplement 436S 439S 2-s2.0-0034789527 (Pubitemid 32948026)
27. Hosseinzadeh L., Khorand A., Aliabadi A., Discovery of 2-Phenyl-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamid derivatives as apoptosis inducer via caspase pathway with potential anticancer activity. Archiv der Pharmazie: Chemistry in Life Sciences 2013 346 812 818
28. Corsetti G., Pasini E., Assanelli D., Bianchi R., Effects of acute caffeine administration on NOS and Bax/Bcl2 expression in the myocardium of rat. Pharmacological Research 2008 57 1 19 25 2-s2.0-39149092059 10.1016/j.phrs.2007.07.007
29. Mao H. L., Liu P. S., Zheng J. F., Zhang P. H., Zhou L. G., Xin G., Liu C., Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro. Pharmacological Research 2007 56 6 483 492 2-s2.0-36249022057 10.1016/j.phrs.2007.09.010 (Pubitemid 350137770)
30. Conklin K. A., Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness. Integrative Cancer Therapies 2004 3 4 294 300 2-s2.0-9244261938 10.1177/1534735404270335 (Pubitemid 39552423)
31. Öz E., Ilhan M. N., Effects of melatonin in reducing the toxic effects of doxorubicin. Molecular and Cellular Biochemistry 2006 286 1-2 11 15 2-s2.0-33646263853 10.1007/s11010-005-9003-8
32. Ji H.-J., Hu J.-F., Wang Y.-H., Chen X.-Y., Zhou R., Chen N.-H., Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus. European Journal of Pharmacology 2010 636 1-3 96 101 2-s2.0-77952674708 10.1016/j.ejphar.2010.03.038