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Volumn 307, Issue 1, 2014, Pages

Gi proteins mediate activation of the canonical hedgehog pathway in the myocardium

Author keywords

G proteins; Heart failure; Hedgehog; Smoothened

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; G PROTEIN COUPLED RECEPTOR; GLI PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; SMO PROTEIN, MOUSE;

EID: 84903589937     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00166.2014     Document Type: Article
Times cited : (20)

References (33)
  • 1
    • 77649161196 scopus 로고    scopus 로고
    • Sonic hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/ netrin-1/PKC pathway
    • Ahmed RP, Haider KH, Shujia J, Afzal MR, Ashraf M. Sonic hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/ netrin-1/PKC pathway. PLOS ONE 5: e8576, 2010.
    • (2010) PLOS ONE , vol.5
    • Ahmed, R.P.1    Haider, K.H.2    Shujia, J.3    Afzal, M.R.4    Ashraf, M.5
  • 2
    • 79952733097 scopus 로고    scopus 로고
    • Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord
    • Belgacem YH, Borodinsky LN. Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord. Proc Natl Acad Sci USA 108: 4482-4487, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4482-4487
    • Belgacem, Y.H.1    Borodinsky, L.N.2
  • 6
    • 77951932085 scopus 로고    scopus 로고
    • Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways
    • Chinchilla P, Xiao L, Kazanietz MG, Riobo NA. Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways. Cell Cycle 9: 570-579, 2010.
    • (2010) Cell Cycle , vol.9 , pp. 570-579
    • Chinchilla, P.1    Xiao, L.2    Kazanietz, M.G.3    Riobo, N.A.4
  • 7
    • 84872081347 scopus 로고    scopus 로고
    • In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration
    • Choi WY, Gemberling M, Wang J, Holdway JE, Shen MC, Karlstrom RO, Poss KD. In vivo monitoring of cardiomyocyte proliferation to identify chemical modifiers of heart regeneration. Development 140: 660-666, 2013.
    • (2013) Development , vol.140 , pp. 660-666
    • Choi, W.Y.1    Gemberling, M.2    Wang, J.3    Holdway, J.E.4    Shen, M.C.5    Karlstrom, R.O.6    Poss, K.D.7
  • 9
    • 67349089325 scopus 로고    scopus 로고
    • Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation
    • Dyer LA, Kirby ML. Sonic hedgehog maintains proliferation in secondary heart field progenitors and is required for normal arterial pole formation. Dev Biol 330: 305-317, 2009.
    • (2009) Dev Biol , vol.330 , pp. 305-317
    • Dyer, L.A.1    Kirby, M.L.2
  • 10
    • 78349308401 scopus 로고    scopus 로고
    • BMP signaling modulates hedgehog-induced secondary heart field proliferation
    • Dyer LA, Makadia FA, Scott A, Pegram K, Hutson MR, Kirby ML. BMP signaling modulates hedgehog-induced secondary heart field proliferation. Dev Biol 348: 167-176, 2010.
    • (2010) Dev Biol , vol.348 , pp. 167-176
    • Dyer, L.A.1    Makadia, F.A.2    Scott, A.3    Pegram, K.4    Hutson, M.R.5    Kirby, M.L.6
  • 11
    • 84934443730 scopus 로고    scopus 로고
    • A novel and efficient model of coronary artery ligation in the mouse
    • Gao E, Koch WJ. A novel and efficient model of coronary artery ligation in the mouse. Methods Mol Biol 1037: 299-311, 2013.
    • (2013) Methods Mol Biol , vol.1037 , pp. 299-311
    • Gao, E.1    Koch, W.J.2
  • 15
    • 46849087764 scopus 로고    scopus 로고
    • Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice
    • Lavine KJ, Kovacs A, Ornitz DM. Hedgehog signaling is critical for maintenance of the adult coronary vasculature in mice. J Clin Invest 118: 2404-2414, 2008.
    • (2008) J Clin Invest , vol.118 , pp. 2404-2414
    • Lavine, K.J.1    Kovacs, A.2    Ornitz, D.M.3
  • 16
    • 33745129425 scopus 로고    scopus 로고
    • Fibroblast growth factor signals regulate a wave of hedgehog activation that is essential for coronary vascular development
    • Lavine KJ, White AC, Park C, Smith CS, Choi K, Long F, Hui CC, Ornitz DM. Fibroblast growth factor signals regulate a wave of hedgehog activation that is essential for coronary vascular development. Genes Dev 20: 1651-1666, 2006.
    • (2006) Genes Dev , vol.20 , pp. 1651-1666
    • Lavine, K.J.1    White, A.C.2    Park, C.3    Smith, C.S.4    Choi, K.5    Long, F.6    Hui, C.C.7    Ornitz, D.M.8
  • 17
    • 49049108307 scopus 로고    scopus 로고
    • i proteins has little effect on Gli3 protein processing and hedgehog-regulated chick neural tube patterning
    • i proteins has little effect on Gli3 protein processing and hedgehog-regulated chick neural tube patterning. Dev Biol 321: 188-196, 2008.
    • (2008) Dev Biol , vol.321 , pp. 188-196
    • Low, W.C.1    Wang, C.2    Pan, Y.3    Huang, X.Y.4    Chen, J.K.5    Wang, B.6
  • 18
    • 50349087678 scopus 로고    scopus 로고
    • Purification and bioassay of hedgehog ligands for the study of cell death and survival
    • Martinez-Chinchilla P, Riobo NA. Purification and bioassay of hedgehog ligands for the study of cell death and survival. Methods Enzymol 446: 189-204, 2008.
    • (2008) Methods Enzymol , vol.446 , pp. 189-204
    • Martinez-Chinchilla, P.1    Riobo, N.A.2
  • 22
    • 79957613017 scopus 로고    scopus 로고
    • Heterotrimeric Gi proteins link hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration
    • Polizio AH, Chinchilla P, Chen X, Kim S, Manning DR, Riobo NA. Heterotrimeric Gi proteins link hedgehog signaling to activation of Rho small GTPases to promote fibroblast migration. J Biol Chem 286: 19589-19596, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 19589-19596
    • Polizio, A.H.1    Chinchilla, P.2    Chen, X.3    Kim, S.4    Manning, D.R.5    Riobo, N.A.6
  • 23
    • 81855183838 scopus 로고    scopus 로고
    • Sonic hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins
    • Polizio AH, Chinchilla P, Chen X, Manning DR, Riobo NA. Sonic hedgehog activates the GTPases Rac1 and RhoA in a Gli-independent manner through coupling of smoothened to Gi proteins. Sci Signal 4: pt7, 2011.
    • (2011) Sci Signal , vol.4
    • Polizio, A.H.1    Chinchilla, P.2    Chen, X.3    Manning, D.R.4    Riobo, N.A.5
  • 24
    • 33645220566 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase and Akt are essential for sonic hedgehog signaling
    • Riobo NA, Lu K, Ai X, Haines GM, Emerson CP Jr. Phosphoinositide 3-kinase and Akt are essential for sonic hedgehog signaling. Proc Natl Acad Sci USA 103: 4505-4510, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 4505-4510
    • Riobo, N.A.1    Lu, K.2    Ai, X.3    Haines, G.M.4    Emerson Jr., C.P.5
  • 25
    • 33747827890 scopus 로고    scopus 로고
    • Hedgehog signal transduction: Signal integration and cross talk in development and cancer
    • Riobo NA, Lu K, Emerson CP Jr. Hedgehog signal transduction: signal integration and cross talk in development and cancer. Cell Cycle 5: 1612-1615, 2006.
    • (2006) Cell Cycle , vol.5 , pp. 1612-1615
    • Riobo, N.A.1    Lu, K.2    Emerson Jr., C.P.3
  • 28
    • 39149102144 scopus 로고    scopus 로고
    • E-NTPDases and ecto-5′-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings
    • Rücker B, Almeida ME, Libermann TA, Zerbini LF, Wink MR, Sarkis JJ. E-NTPDases and ecto-5′-nucleotidase expression profile in rat heart left ventricle and the extracellular nucleotide hydrolysis by their nerve terminal endings. Life Sci 82: 477-486, 2008.
    • (2008) Life Sci , vol.82 , pp. 477-486
    • Rücker, B.1    Almeida, M.E.2    Libermann, T.A.3    Zerbini, L.F.4    Wink, M.R.5    Sarkis, J.J.6
  • 29
    • 33645211374 scopus 로고    scopus 로고
    • Purmorphamine activates the hedgehog pathway by targeting smoothened
    • Sinha S, Chen JK. Purmorphamine activates the hedgehog pathway by targeting smoothened. Nat Chem Biol 2: 29-30, 2006.
    • (2006) Nat Chem Biol , vol.2 , pp. 29-30
    • Sinha, S.1    Chen, J.K.2
  • 31
    • 0034681266 scopus 로고    scopus 로고
    • Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
    • Wang B, Fallon JF, Beachy PA. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434, 2000.
    • (2000) Cell , vol.100 , pp. 423-434
    • Wang, B.1    Fallon, J.F.2    Beachy, P.A.3
  • 32
    • 0028003464 scopus 로고
    • G protein expression and adenylate cyclase regulation in ventricular cardiomyocytes from STZdiabetic rats
    • Wichelhaus A, Russ M, Petersen S, Eckel J. G protein expression and adenylate cyclase regulation in ventricular cardiomyocytes from STZdiabetic rats. Am J Physiol Heart Circ Physiol 267: H548-H555, 1994.
    • (1994) Am J Physiol Heart Circ Physiol , vol.267
    • Wichelhaus, A.1    Russ, M.2    Petersen, S.3    Eckel, J.4
  • 33
    • 84865264805 scopus 로고    scopus 로고
    • Impaired sonic hedgehog pathway contributes to cardiac dysfunction in type 1 diabetic mice with myocardial infarction
    • Xiao Q, Hou N, Wang YP, He LS, He YH, Zhang GP, Yi Q, Liu SM, Chen MS, Luo JD. Impaired sonic hedgehog pathway contributes to cardiac dysfunction in type 1 diabetic mice with myocardial infarction. Cardiovasc Res 95: 507-516, 2012.
    • (2012) Cardiovasc Res , vol.95 , pp. 507-516
    • Xiao, Q.1    Hou, N.2    Wang, Y.P.3    He, L.S.4    He, Y.H.5    Zhang, G.P.6    Yi, Q.7    Liu, S.M.8    Chen, M.S.9    Luo, J.D.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.