메뉴 건너뛰기




Volumn 9, Issue 6, 2014, Pages

A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis

(25)  Real, Luis M a,b,c   Ruiz, Agustín a,d   Gayán, Javier a,e   González Pérez, Antonio a,f   Sáez, María E a,f   Ramírez Lorca, Reposo a,c   Morón, Francisco J a,c   Velasco, Juan a,g   Marginet Flinch, Ruth a,h   Musulén, Eva h   Carrasco, José M a   Moreno Rey, Concha a,i   Vázquez, Enrique a   Chaves Conde, Manuel i   Moreno Nogueira, Jose A i   Hidalgo Pascual, Manuel j   Ferrero Herrero, Eduardo j   Castellví Bel, Sergi k   Castells, Antoni k   Fernandez Rozadilla, Ceres l   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BASE PAIRING; CANCER SUSCEPTIBILITY; CHROMOSOME; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; ETHNICITY; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; SINGLE NUCLEOTIDE POLYMORPHISM; SPANISH; CHROMOSOME 4; COLORECTAL TUMOR; GENETIC DATABASE; GENETIC PREDISPOSITION; GENETICS; META ANALYSIS (TOPIC); REPRODUCIBILITY; SPAIN;

EID: 84903555268     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0101178     Document Type: Article
Times cited : (24)

References (43)
  • 3
    • 42349112088 scopus 로고    scopus 로고
    • Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
    • McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, et al. (2008) Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 9: 356-369.
    • (2008) Nat Rev Genet , vol.9 , pp. 356-369
    • McCarthy, M.I.1    Abecasis, G.R.2    Cardon, L.R.3    Goldstein, D.B.4    Little, J.5
  • 4
    • 37549072226 scopus 로고    scopus 로고
    • Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk
    • Jaeger E, Webb E, Howarth K, Carvajal-Carmona L, Rowan A, et al. (2008) Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet 40: 26-28.
    • (2008) Nat Genet , vol.40 , pp. 26-28
    • Jaeger, E.1    Webb, E.2    Howarth, K.3    Carvajal-Carmona, L.4    Rowan, A.5
  • 5
    • 84863005628 scopus 로고    scopus 로고
    • Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
    • Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, et al. (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet 44: 770-776.
    • (2012) Nat Genet , vol.44 , pp. 770-776
    • Dunlop, M.G.1    Dobbins, S.E.2    Farrington, S.M.3    Jones, A.M.4    Palles, C.5
  • 6
    • 78049353079 scopus 로고    scopus 로고
    • Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33
    • Houlston RS, Cheadle J, Dobbins SE, Tenesa A, Jones AM, et al. (2010) Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat Genet 42: 973-977.
    • (2010) Nat Genet , vol.42 , pp. 973-977
    • Houlston, R.S.1    Cheadle, J.2    Dobbins, S.E.3    Tenesa, A.4    Jones, A.M.5
  • 7
    • 56749176944 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
    • Houlston RS, Webb E, Broderick P, Pittman AM, Di Bernardo MC, et al. (2008) Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet 40: 1426-1435.
    • (2008) Nat Genet , vol.40 , pp. 1426-1435
    • Houlston, R.S.1    Webb, E.2    Broderick, P.3    Pittman, A.M.4    Di Bernardo, M.C.5
  • 8
    • 84873080361 scopus 로고    scopus 로고
    • Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer
    • Jia WH, Zhang B, Matsuo K, Shin A, Xiang YB, et al. (2013) Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer. Nat Genet 45: 191-196.
    • (2013) Nat Genet , vol.45 , pp. 191-196
    • Jia, W.H.1    Zhang, B.2    Matsuo, K.3    Shin, A.4    Xiang, Y.B.5
  • 9
    • 84856703651 scopus 로고    scopus 로고
    • Meta-analysis of new genome-wide association studies of colorectal cancer risk
    • Peters U, Hutter CM, Hsu L, Schumacher FR, Conti DV, et al. (2012) Meta-analysis of new genome-wide association studies of colorectal cancer risk. Hum Genet 131: 217-234.
    • (2012) Hum Genet , vol.131 , pp. 217-234
    • Peters, U.1    Hutter, C.M.2    Hsu, L.3    Schumacher, F.R.4    Conti, D.V.5
  • 10
    • 84875253066 scopus 로고    scopus 로고
    • Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis
    • Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, et al. (2013) Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. Gastroenterology 144: 799-807 e724.
    • (2013) Gastroenterology , vol.144
    • Peters, U.1    Jiao, S.2    Schumacher, F.R.3    Hutter, C.M.4    Aragaki, A.K.5
  • 11
    • 42649124305 scopus 로고    scopus 로고
    • Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
    • Tenesa A, Farrington SM, Prendergast JG, Porteous ME, Walker M, et al. (2008) Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet 40: 631-637.
    • (2008) Nat Genet , vol.40 , pp. 631-637
    • Tenesa, A.1    Farrington, S.M.2    Prendergast, J.G.3    Porteous, M.E.4    Walker, M.5
  • 12
    • 34547498546 scopus 로고    scopus 로고
    • A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21
    • Tomlinson I, Webb E, Carvajal-Carmona L, Broderick P, Kemp Z, et al. (2007) A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 39: 984-988.
    • (2007) Nat Genet , vol.39 , pp. 984-988
    • Tomlinson, I.1    Webb, E.2    Carvajal-Carmona, L.3    Broderick, P.4    Kemp, Z.5
  • 13
    • 79959851441 scopus 로고    scopus 로고
    • Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer
    • Tomlinson IP, Carvajal-Carmona LG, Dobbins SE, Tenesa A, Jones AM, et al. (2011) Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer. PLoS Genet 7: e1002105.
    • (2011) PLoS Genet , vol.7
    • Tomlinson, I.P.1    Carvajal-Carmona, L.G.2    Dobbins, S.E.3    Tenesa, A.4    Jones, A.M.5
  • 14
    • 42649136554 scopus 로고    scopus 로고
    • A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3
    • Tomlinson IP, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, et al. (2008) A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 40: 623-630.
    • (2008) Nat Genet , vol.40 , pp. 623-630
    • Tomlinson, I.P.1    Webb, E.2    Carvajal-Carmona, L.3    Broderick, P.4    Howarth, K.5
  • 15
    • 34547092701 scopus 로고    scopus 로고
    • Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24
    • Zanke BW, Greenwood CM, Rangrej J, Kustra R, Tenesa A, et al. (2007) Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 39: 989-994.
    • (2007) Nat Genet , vol.39 , pp. 989-994
    • Zanke, B.W.1    Greenwood, C.M.2    Rangrej, J.3    Kustra, R.4    Tenesa, A.5
  • 16
    • 84876950573 scopus 로고    scopus 로고
    • Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals
    • Dunlop MG, Tenesa A, Farrington SM, Ballereau S, Brewster DH, et al. (2013) Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42,103 individuals. Gut 62: 871-881.
    • (2013) Gut , vol.62 , pp. 871-881
    • Dunlop, M.G.1    Tenesa, A.2    Farrington, S.M.3    Ballereau, S.4    Brewster, D.H.5
  • 18
    • 51349122031 scopus 로고    scopus 로고
    • A method for detecting epistasis in genome-wide studies using case-control multilocus association analysis
    • Gayan J, Gonzalez-Perez A, Bermudo F, Saez ME, Royo JL, et al. (2008) A method for detecting epistasis in genome-wide studies using case-control multilocus association analysis. BMC Genomics 9: 360.
    • (2008) BMC Genomics , vol.9 , pp. 360
    • Gayan, J.1    Gonzalez-Perez, A.2    Bermudo, F.3    Saez, M.E.4    Royo, J.L.5
  • 19
    • 58949084541 scopus 로고    scopus 로고
    • Genetic association tests in the presence of epistasis or gene-environment interaction
    • Wang K (2008) Genetic association tests in the presence of epistasis or gene-environment interaction. Genet Epidemiol 32: 606-614.
    • (2008) Genet Epidemiol , vol.32 , pp. 606-614
    • Wang, K.1
  • 20
    • 34548352849 scopus 로고    scopus 로고
    • Bayesian inference of epistatic interactions in case-control studies
    • Zhang Y, Liu JS (2007) Bayesian inference of epistatic interactions in case-control studies. Nat Genet 39: 1167-1173.
    • (2007) Nat Genet , vol.39 , pp. 1167-1173
    • Zhang, Y.1    Liu, J.S.2
  • 21
    • 84871535193 scopus 로고    scopus 로고
    • Genome-wide search for gene-gene interactions in colorectal cancer
    • Jiao S, Hsu L, Berndt S, Bezieau S, Brenner H, et al. (2012) Genome-wide search for gene-gene interactions in colorectal cancer. PLoS One 7: e52535.
    • (2012) PLoS One , vol.7
    • Jiao, S.1    Hsu, L.2    Berndt, S.3    Bezieau, S.4    Brenner, H.5
  • 22
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 23
    • 84872801878 scopus 로고    scopus 로고
    • A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12
    • Fernandez-Rozadilla C, Cazier JB, Tomlinson IP, Carvajal-Carmona LG, Palles C, et al. (2013) A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12. BMC Genomics 14: 55.
    • (2013) BMC Genomics , vol.14 , pp. 55
    • Fernandez-Rozadilla, C.1    Cazier, J.B.2    Tomlinson, I.P.3    Carvajal-Carmona, L.G.4    Palles, C.5
  • 24
    • 77953225304 scopus 로고    scopus 로고
    • Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma
    • Arai Y, Honda S, Haruta M, Kasai F, Fujiwara Y, et al. (2010) Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma. Genes Chromosomes Cancer 49: 596-609.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 596-609
    • Arai, Y.1    Honda, S.2    Haruta, M.3    Kasai, F.4    Fujiwara, Y.5
  • 25
    • 63449140725 scopus 로고    scopus 로고
    • Genomic profiles associated with early micrometastasis in lung cancer: Relevance of 4q deletion
    • Wrage M, Ruosaari S, Eijk PP, Kaifi JT, Hollmen J, et al. (2009) Genomic profiles associated with early micrometastasis in lung cancer: relevance of 4q deletion. Clin Cancer Res 15: 1566-1574.
    • (2009) Clin Cancer Res , vol.15 , pp. 1566-1574
    • Wrage, M.1    Ruosaari, S.2    Eijk, P.P.3    Kaifi, J.T.4    Hollmen, J.5
  • 26
    • 33644860129 scopus 로고    scopus 로고
    • Genome-wide differences between microsatellite stable and unstable colorectal tumors
    • Camps J, Armengol G, del Rey J, Lozano JJ, Vauhkonen H, et al. (2006) Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis 27: 419-428.
    • (2006) Carcinogenesis , vol.27 , pp. 419-428
    • Camps, J.1    Armengol, G.2    Del Rey, J.3    Lozano, J.J.4    Vauhkonen, H.5
  • 27
    • 84879405575 scopus 로고    scopus 로고
    • NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer
    • Tzeng ST, Tsai MH, Chen CL, Lee JX, Jao TM, et al. (2013) NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer. PLoS One 8: e67040.
    • (2013) PLoS One , vol.8
    • Tzeng, S.T.1    Tsai, M.H.2    Chen, C.L.3    Lee, J.X.4    Jao, T.M.5
  • 28
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs: Insights into functions
    • Mercer TR, Dinger ME, Mattick JS (2009) Long non-coding RNAs: insights into functions. Nat Rev Genet 10: 155-159.
    • (2009) Nat Rev Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 29
    • 84861904178 scopus 로고    scopus 로고
    • Genome regulation by long noncoding RNAs
    • Rinn JL, Chang HY (2012) Genome regulation by long noncoding RNAs. Annu Rev Biochem 81: 145-166.
    • (2012) Annu Rev Biochem , vol.81 , pp. 145-166
    • Rinn, J.L.1    Chang, H.Y.2
  • 30
    • 0036122682 scopus 로고    scopus 로고
    • Cloning of the mRNA of overexpression in colon carcinoma-1: A sequence overexpressed in a subset of colon carcinomas
    • Pibouin L, Villaudy J, Ferbus D, Muleris M, Prosperi MT, et al. (2002) Cloning of the mRNA of overexpression in colon carcinoma-1: a sequence overexpressed in a subset of colon carcinomas. Cancer Genet Cytogenet 133: 55-60.
    • (2002) Cancer Genet Cytogenet , vol.133 , pp. 55-60
    • Pibouin, L.1    Villaudy, J.2    Ferbus, D.3    Muleris, M.4    Prosperi, M.T.5
  • 31
    • 84875057736 scopus 로고    scopus 로고
    • Long non-coding RNA in cancer
    • Hauptman N, Glavac D (2013) Long non-coding RNA in cancer. Int J Mol Sci 14: 4655-4669.
    • (2013) Int J Mol Sci , vol.14 , pp. 4655-4669
    • Hauptman, N.1    Glavac, D.2
  • 32
    • 84890000516 scopus 로고    scopus 로고
    • Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer
    • Li L, Sun R, Liang Y, Pan X, Li Z, et al. (2013) Association between polymorphisms in long non-coding RNA PRNCR1 in 8q24 and risk of colorectal cancer. J Exp Clin Cancer Res 32: 104.
    • (2013) J Exp Clin Cancer Res , vol.32 , pp. 104
    • Li, L.1    Sun, R.2    Liang, Y.3    Pan, X.4    Li, Z.5
  • 35
    • 84888610885 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects
    • World Medical Association
    • World Medical Association (2013) World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 310: 2191-2194.
    • (2013) JAMA , vol.310 , pp. 2191-2194
  • 38
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904-909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5
  • 39
    • 46149098096 scopus 로고    scopus 로고
    • Long-range LD can confound genome scans in admixed populations
    • author reply 135-139
    • Price AL, Weale ME, Patterson N, Myers SR, Need AC, et al. (2008) Long-range LD can confound genome scans in admixed populations. Am J Hum Genet 83: 132-135; author reply 135-139.
    • (2008) Am J Hum Genet , vol.83 , pp. 132-135
    • Price, A.L.1    Weale, M.E.2    Patterson, N.3    Myers, S.R.4    Need, A.C.5
  • 41
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 42
    • 0026702157 scopus 로고
    • Confidence interval estimation of interaction
    • Hosmer DW, Lemeshow S (1992) Confidence interval estimation of interaction. Epidemiology 3: 452-456.
    • (1992) Epidemiology , vol.3 , pp. 452-456
    • Hosmer, D.W.1    Lemeshow, S.2
  • 43
    • 0032915780 scopus 로고    scopus 로고
    • Case-only design to measure gene-gene interaction
    • Yang Q, Khoury MJ, Sun F, Flanders WD (1999) Case-only design to measure gene-gene interaction. Epidemiology 10: 167-170.
    • (1999) Epidemiology , vol.10 , pp. 167-170
    • Yang, Q.1    Khoury, M.J.2    Sun, F.3    Flanders, W.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.